CafeMedico CafeMedico Supportive Cancer Care with Chinese Medicine CafeMedico William C.S. Cho Editor Supportive Cancer Care with Chinese Medicine 1 3 CafeMedico Editor Dr.WilliamChi-ShingCho DepartmentClinicalOncology QueenElizabethHospital 13/FBlockR30GascoigneRoad Kowloon HongKongSAR [email protected] ISBN978-90-481-3554-7 e-ISBN978-90-481-3555-4 DOI10.1007/978-90-481-3555-4 SpringerDordrechtHeidelbergLondonNewYork LibraryofCongressControlNumber:2009942718 ©SpringerScience+BusinessMediaB.V.2010 Nopartofthisworkmaybereproduced,storedinaretrievalsystem,ortransmittedinanyformorby anymeans,electronic,mechanical,photocopying,microfilming,recordingorotherwise,withoutwritten permissionfromthePublisher,withtheexceptionofanymaterialsuppliedspecificallyforthepurpose ofbeingenteredandexecutedonacomputersystem,forexclusiveusebythepurchaserofthework. Printedonacid-freepaper SpringerispartofSpringerScience+BusinessMedia(www.springer.com) CafeMedico Preface Cancer is a chronic disease. There are increasing cancer survivors after curative cancertreatmentandthismakessupportivecancercareanimportantareathatmore attentionisneeded.Chinesemedicinehasalonghistoryofpractice;ithasaroused much interest from both Oriental and Western countries. A number of laboratory evidencesandclinicaltrialsdemonstratedtheeffectivenessandefficaciesofChinese medicine for supportive cancer care. This book attempts to take a comprehensive approachtooverviewthedifferentareasofChinesemedicineforsupportivecancer care. Thisbooknotonlyservesasanintroductiontonovicestotheareaandauseful referenceforthosealreadyinvolved,butalsoservesasastimulustotheseandothers toemployalternativeapproachestocurrentcancercare. HongKong WilliamC.S.Cho December2009 v CafeMedico Contents 1 SupportiveCancerCareUsingChineseMedicine . . . . . . . . . . 1 RaimondWongandStephenM.Sagar 2 SupportiveCancerCarewithAcupuncture . . . . . . . . . . . . . 39 Jaung-GengLinandYi-HungChen 3 ChineseMedicinalHerbsUseinManagingCancer . . . . . . . . . 55 PeterDorsherandZengfuPeng 4 SupportiveCancerCarewithQigong . . . . . . . . . . . . . . . . . 77 MyeongSooLee,KevinW.ChenandEdzardErnst 5 Traditional Chinese Medicine in the Reduction of DiscomfortandSide-EffectsofSurgery. . . . . . . . . . . . . . . . 95 Kok-YangTan,XiaoxiuWuandFrancisSeow-Choen 6 Increasing Therapeutic Gain and Controlling Radiation-InducedInjurieswithAsianBotanicalsandAcupuncture 109 StephenM.SagarandRaimondK.Wong 7 ControllingChemotherapy-RelatedSideEffectswith ChineseMedicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 Shwu-HueyLiu,Yung-ChiCheng,andMuhammadW.Saif 8 CancerPainControlwithTraditionalChineseMedicine . . . . . . 169 TingBao,LixingLao,andAdityaBardia 9 NovelDevelopmentsonArtemisininandItsDerivativesfor CancerTherapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 SerkanSertel,PeterK.Plinkert,andThomasEfferth 10 ModernCancerResearchonChineseMedicine:Acupuncture . . . 253 RuixinZhangandLixingLao 11 ClinicalTrialsofChineseMedicinefortheTreatmentofCancer. . 271 HenryL.M.LiangandDennisH.T.Chang vii CafeMedico viii Contents 12 Toxicology,SafetyandHerb–drugInteractionsinCancerTherapy 293 Shu-FengZhou 13 IntegratingChineseandWesternMedicineinCancerTreatment . 341 DeliaChiaramonteandLixingLao 14 Traditional Chinese Medicine in the Prevention and TreatmentofCancerDisease:AReviewoftheEvidence . . . . . . 363 JianpingLiu,XunLi,HuijuanCao,andTorkelSnellingen Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381 CafeMedico Contributors TingBao MarleneandStewartGreenebaumCancerCenter;SchoolofMedicine, CenterforIntegrativeMedicine,UniversityofMaryland,Baltimore,MD,USA, [email protected] AdityaBardia SchoolofMedicine,TheSidneyKimmelComprehensiveCancer Center,JohnsHopkinsUniversity,Baltimore,MD,USA,[email protected] HuijuanCao CentreforEvidenceBasedChineseMedicine,BeijingUniversityof ChineseMedicine,Beijing,China,[email protected] DennisHTChang CollegeofHealthandScience,CentreforComplementary MedicineResearch,PenrithSouthDC,NSW,Australia,[email protected] Yi-HungChen GraduateInstituteofAcupunctureScience,ChinaMedical University,Taichung,Taiwan,[email protected] KevinW.Chen CenterforIntegrativeMedicine,UniversityofMarylandSchool ofMedicine,Baltimore,MD,USA,[email protected] Yung-ChiCheng PharmacologyDepartment,SchoolofMedicine,Yale University,NewHaven,CT,USA,[email protected] DeliaChiaramonte CenterforIntegrativeMedicine,SchoolofMedicine, UniversityofMaryland,Baltimore,MD,USA,[email protected] PeterDorsher MayoClinic,Rochester,MN,USA,[email protected] ThomasEfferth GermanCancerResearchCentre(DKFZ),Pharmaceutical Biology(C015),Heidelberg,Germany,[email protected] EdzardErnst ComplementaryMedicine,PeninsulaMedicalSchool,Universities ofExeterandPlymouth,Exeter,UK,[email protected] LixingLao SchoolofMedicine,CenterforIntegrativeMedicine,Universityof Maryland,Baltimore,MD,USA,[email protected] MyeongS.Lee DivisionofStandardResearch,KoreaInstituteofOriental Medicine,Daejeon,SouthKorea;ComplementaryMedicine,PeninsulaMedical School,UniversitiesofExeterandPlymouth,Exeter,UK,[email protected] [email protected] ix CafeMedico x Contributors XunLi CentreforEvidenceBasedChineseMedicine,BeijingUniversityof ChineseMedicine,Beijing,China,[email protected] HenryLMLiang CollegeofHealthandScience,CentreforComplementary MedicineResearch,UniversityofWesternSydney,PenrithSouthDC,NSW, Australia,[email protected] Jaung-GengLin GraduateInstituteofChineseMedicalScience,ChinaMedical University,Taichung,Taiwan,[email protected]. Shwu-HueyLiu PhytoCeuticaInc,NewHaven,CT,USA, [email protected] JianpingLiu CentreforEvidenceBasedChineseMedicine,BeijingUniversityof ChineseMedicine,Beijing,China,[email protected] ZengfuPeng MayoClinic,Rochester,MN,USA,[email protected] PeterKPlinkert DepartmentofOtorhinolaryngology,HeadandNeckSurgery, UniversityHeidelberg,Heidelberg,Germany,peter.plinkert@med. uni-heidelberg.de StephenM.Sagar RadiationOncology,JuravinskiCancerCentre,Hamilton,ON, Canada,[email protected] MuhammadW.Saif PharmacologyDepartment;DepartmentofMedicine, SchoolofMedicine,YaleCancerCenter,YaleUniversity,NewHaven,CT,USA, [email protected] FrancisSeow-Choen Seow-ChoenColorectalCentre,3MtElizabethMedical Centre,Singapore,[email protected] SerkanSertel DepartmentofOtorhinolaryngology,HeadandNeckSurgery, UniversityHeidelberg;GermanCancerResearchCentre(DKFZ),Pharmaceutical Biology(C015),Heidelberg,Germany,[email protected] ZhouShu-feng DisciplineofChineseMedicine,SchoolofHealthSciences, RMITUniversity,Bundoora,VIC,Australia,[email protected] TorkelSnellingen CentreforInternationalHealth,UniversityofTromsø,Tromsø, Norway,[email protected] Kok-YangTan DepartmentofSurgery,ColorectalService,AlexandraHospital, Singapore,[email protected] RaimondK.Wong DepartmentofMedicine,JuravinskiCancerCentre, McMasterUniversity,Hamilton,ON,Canada,[email protected] XiaoxiuWu BeijingTon-Ren-TangScienceArts(Singapore)Co.Pte.Ltd, Singapore,[email protected] RuixinZhang SchoolofMedicine,CenterforIntegrativeMedicine,Universityof Maryland,Baltimore,MD,USA,[email protected] CafeMedico Chapter 1 Supportive Cancer Care Using Chinese Medicine RaimondWongandStephenM.Sagar Abstract Complementary and alternative medicine (CAM) has been increasingly utilized by cancer patients in developed countries. Among the various forms of CAM, traditional Chinese medicine (TCM) is one of the few that has a well con- structed theoretical framework and established treatment approaches for diseases including cancer. Recent research has revealed growing evidence suggesting that TCM is effective in the supportive care of cancer patients during and after major conventional cancer treatments (surgery, chemotherapy and radiotherapy). This effectivenessseemstomediatemainlythroughthreeapproaches:(1)Improvement oftumourresponseandreductionofadversetreatmenteffects;(2)Immunitymodu- lationand(3)Enhancementofsymptomcontrol.Thischapterreviewedtheconcepts behindwhichTCMtreatmentapproaches insupportivecareofcancer patientsare formulatedandthepublishedlaboratoryandclinicalevidencesupportingtheusage ofvariousTCMtreatmentstrategiesincludingherbalmedicine,acupuncture,dietary modificationsandqigongenergytherapy. 1.1 Introduction Upto80%ofcancerpatientsintheWesterncountrieshaveutilizedsomeformsof complementaryandalternativemedicine(CAM)tosupporttheirconventionalcan- certherapies(ErnstandCassileth1998;Boonetal.1999).Amongthevariousforms ofCAM,traditionalChinesemedicine(TCM)isoneofthefewthathasawellcon- structed theoretical framework and established treatment approaches for diseases includingcancer.Initscountryoforigin,TCMhasbeenusedforthousandsofyears fortreatingcancersandcontinuoustobeawellacceptedformoftreatmentmodality foreffectivecancermanagement,particularlywhenusedincombinationwithother majorconventionaltherapiessuchassurgery,radiotherapyandchemotherapy. B R.Wong( ) JuravinskiCancerCentre,Hamilton,ON,L8V5C2,Canada e-mail:[email protected] W.C.S.Cho(ed.),SupportiveCancerCarewithChineseMedicine, 1 DOI10.1007/978-90-481-3555-4_1,(cid:2)C SpringerScience+BusinessMediaB.V.2010
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