Special Issue Substance and Behavioral Addictions: Co-Occurrence and Specificity 2012 Steve Sussman (Ed.) MDPI OPEN ACCESS ExternalEditors EditorialOffice Editor-in-Chief MDPIAG Prof. Dr. PaulB.Tchounwou Kandererstrasse25 MolecularToxicologyResearchLaboratory Basel,Switzerland JacksonStateUniversity Phone: +41616837734 Jackson,Mississippi39217,USA Website: http://www.mdpi.com/journal/ijerph/ Phone: +16019793321 E-Mail: [email protected] Fax: +16019792349 Website: http://www.jsums.edu/cset/Biology/ Publisher faculty/tchounwou.htm Dr. Shu-KunLin E-Mail: [email protected] ProductionEditor GuestEditor Dr. BriettaPike Prof. Dr. SteveSussman Institute for Health Promotion and Disease ManagingEditor PreventionResearch Ms. MasoomaHassan DivisionofHealthBehaviorResearch Department of Preventive Medicine, School ofMedicine DepartmentofPsychology,SchoolofLiberal ArtsandSciences UniversityofSouthernCalifornia SotoStreetBuilding 2001NorthSotoStreet,Room302A LosAngeles,CA90032-3628,USA Phone: +13234428220 Fax: +13234428201 E-Mail: [email protected] Coverpicture: IhrzuFu¨ßen! Author: GustavImlauer In: U¨ber Land und Meer. Allgemeine illustrirteZeitung,H.13,1883,S.265 Availableonlineat: simple.wikipedia.org/wiki/ File:Imlauer Ihr zu Fuessen 1883.jpg ISBN3-906980-32-4 Table of Contents Preface SteveSussman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . I AFrameworkfortheSpecificityofAddictions Steve Sussman, Adam Leventhal, Ricky N. Bluthenthal, Marilyn Freimuth, Myriam Forster andSusanL.Ames Int. J.Environ. Res. PublicHealth2011,8,3399-3415;doi:10.3390/ijerph8083399 . . . . 1 Generational Association Studies of Dopaminergic Genes in Reward Deficiency Syn- drome (RDS) Subjects: Selecting Appropriate Phenotypes for Reward Dependence Be- haviors KennethBlum,AmandaL.C.Chen,MarleneOscar-Berman,ThomasJ.H.Chen,JoelLubar, Nancy White, Judith Lubar, Abdalla Bowirrat, Eric Braverman, John Schoolfield, Roger L. Waite, Bernard W. Downs, Margaret Madigan, David E. Comings, Caroline Davis, Mal- lory M. Kerner, Jennifer Knopf, Tomas Palomo, John J. Giordano, Siobhan A. Morse, Frank Fornari,DebmalyaBarh,JohnFeminoandJohnA.Bailey Int. J.Environ. Res. PublicHealth2011,8,4425-4459;doi:10.3390/ijerph8124425 . . . . 18 Long-Term Effects of Self-Control on Alcohol Use and Sexual Behavior among Urban MinorityYoungWomen Kenneth W. Griffin, Lawrence M. Scheier, Bianca Acevedo, Jerry L. Grenard and Gilbert J. Botvin Int. J.Environ. Res. PublicHealth2012,9,1-23;doi:10.3390/ijerph9010001 . . . . . . . . 53 ClarifyingExerciseAddiction: DifferentialDiagnosis,Co-occurringDisorders,andPhases ofAddiction MarilynFreimuth,SandyMonizandShariR.Kim Int. J.Environ. Res. PublicHealth2011,8,4069-4081;doi:10.3390/ijerph8104069 . . . . 76 ExtensiveInternetInvolvement—AddictionorEmergingLifestyle? KarinHelmerssonBergmark,AndersBergmarkandOlleFindahl Int. J.Environ. Res. PublicHealth2011,8,4488-4501;doi:10.3390/ijerph8124488 . . . . 89 Concurrent and Predictive Relationships Between Compulsive Internet Use and Sub- stanceUse: FindingsfromVocationalHighSchoolStudentsinChinaandtheUSA Ping Sun, Carl Anderson Johnson, Paula Palmer, Thalida E. Arpawong, Jennifer B. Unger, BinXie,LouiseA.Rohrbach,DonnaSpruijt-MetzandSteveSussman Int. J.Environ. Res. PublicHealth2012,9,660-673;doi:10.3390/ijerph9030660 . . . . . . 103 OnlineSocialNetworkingandAddiction—AReviewofthePsychologicalLiterature DariaJ.KussandMarkD.Griffiths Int. J.Environ. Res. PublicHealth2011,8,3528-3552;doi:10.3390/ijerph8093528 . . . . 117 High Calorie, Low Nutrient Food/Beverage Intake and Video Gaming in Children as PotentialSignalsforAddictiveBehavior MaryAnnPentz,DonnaSpruijt-Metz,ChihPingChouandNathanielR.Riggs Int. J.Environ. Res. PublicHealth2011,8,4406-4424;doi:10.3390/ijerph8124406 . . . . 142 PatternsofandMotivationsforConcurrentUseofVideoGamesandSubstances GeoffreyL.Ream,LutherC.ElliottandEloiseDunlap Int. J.Environ. Res. PublicHealth2011,8,3999-4012;doi:10.3390/ijerph8103999 . . . . 161 Playing Video Games While Using or Feeling the Effects of Substances: Associations withSubstanceUseProblems GeoffreyL.Ream,LutherC.ElliottandEloiseDunlap Int. J.Environ. Res. PublicHealth2011,8,3979-3998;doi:10.3390/ijerph8103979 . . . . 175 ConsideringtheDefinitionofAddiction SteveSussmanandAlanN.Sussman Int. J.Environ. Res. PublicHealth2011,8,4025-4038;doi:10.3390/ijerph8104025 . . . . 195 I Preface Researchers and practitioners have discussed the existence of several types of substance and behavioral addictions. That is, in general, they have agreed that individuals may fall victim to maladaptive, repetitive patterns of behavior involving recreational drugs (e.g., tobacco, alcohol, illicit drugs), other substances (e.g., binge eating), and other behaviors (e.g., gambling, the internet, shopping, workaholism, exercise addiction, love, or sex), that reflect attempts at achievement of appetitive physiological outcomes but result eventually in negative outcomes to self or others. Research over the last two decades suggests that a wide range of substance and behavioral addictions may serve similar functions. Overall, 12-month prevalence of one or more of the 11 addictions just listed above among adults in the U.S. has been estimated to be 46% based on an exhaustive review of the literature [1]. As such, it may be useful to think of the addictions in terms of problems of lifestyle as well as of a person. Yet, “co-occurrence” of addictions has been reported among only a minority of sufferers, and is estimated to be approximately 23% [1]. “Addiction specificity” pertains to a phenomenon in which one pattern of addiction may be acquired whereas another is not [2]. Differential patterns of addiction may be a function of such variables as accessibility, intrinsic appetitive effects, differential socialization, and specific outcome expectations. The present Special Issue examines addiction co-occurrence and addiction specificity across several addictive behaviors. The goal of the Issue is to comprehensively describe notable addictive behaviors, and elaborate on what the associational pathways might be of addiction co-occurrence and specificity. A total of 11 papers are included. The first paper by Sussman et al. [2] introduces the topic of the Special Issue and presents a model that might help explain addiction specificity (the “PACE” model). Pragmatics (e.g., access), attraction (e.g., subjective effects), communication (e.g., addictive behavior jargon), and expectation (e.g., number of experiential solutions provided by a given addictive behavior) variables are described, and examples in the development of different addictions are derived from this model. The second paper by Blum et al. [3] presents literature on the Reward Deficiency Syndrome, and how it might apply to various addictions and other problem behaviors as a nonspecific reward phenotype. Further, these authors present results of a genotype analysis which indicates extremely high presence of certain gene alleles (e.g., TacA1) across two families with high prevalence of the phenotype. Their article highlights more an underlying potential mechanism of addiction co-occurrence which might fall mostly within the “A” (attraction) facet of the PACE model. The third paper by Griffin et al. [4] examines the prospective relationships of alcohol use and sexual behavior among urban minority women from the beginning of high school to young adulthood, eight years later. Self-control was found to serve as a protective factor of latent class membership — those who would end up exhibiting low levels on both behaviors, high levels of alcohol use-low levels of risky sexual behavior, or high levels on both behaviors. This paper II highlighted both the operations of addition co-occurrence and specificity and one potential determinant (lack of self-control; also an “A” variable). The fourth paper by Freimuth et al. [5] provides one of the first reviews of exercise addiction, how it might develop, and its developmental specificity (e.g., reliance on exercise for its mood altering effects) and co-occurrence (e.g., with eating disorders, alcohol use). Treatment implications of exercise addiction also are discussed. The next three papers pertain to internet addiction. The fifth paper by Bergmark et al. [6] provides data from a large Swedish survey on internet use (mean age of sample = 45 years). It is observed that while face-to-face contact is decreased due to internet use, total number of social contacts appears to increase. Addiction-type problems pertaining to internet use appear to be a function of engaging in time intensive activities such as online gaming. Internet addiction may be best understood as being a modality in which other types of addictions (e.g., gambling, sex) are expressed. The sixth paper by Sun et al. [7] presents data from Chinese and U.S. adolescents on the bidirectional one-year prospective relationships between compulsive internet use and drug use (cigarette smoking and alcohol binge drinking). Each behavior predicted itself over time. In addition, compulsive internet use positively predicted later smoking or binge drinking among females but not males, in both countries. The authors speculate that females that take on male gender roles, possibly through on-line gaming, are at relatively greater risk for drug use (illustrating both addiction co-occurrence and specificity). The seventh paper by Kuss et al. [8] is the first review paper on social network sites (SNS) addiction. While SNS are used mainly for maintenance of offline pre-established social networks, relatively high levels of use are related to decrease in real life social participation, relationship problems, and academic achievement, suggestive of addiction. There may be co-occurrence of SNS addiction with drug misuse and overeating. The next three papers pertain to playing videogames. The eighth paper by Pentz et al. [9] examines the relations among high calorie, low nutrient (HCLN) intake and videogaming among a large sample of initially 9-to-10 year olds over an 18 month period. Male gender, free/reduced lunch, low perceived physical safety and low inhibitory control predicted both behaviors, whereas ethnicity and low stress predicted HCLN intake. Possibly, staying indoors (that may characterize some poor areas), may reflect a “P” (pragmatics) variable conducive to both behaviors. The ninth and tenth papers, both by Ream, Elliott, and Dunlap [10,11] were drawn from a nationally-representative survey of U.S. adults who regularly or occasionally played videogames and had played at least one hour in the past week. These authors found that problem videogame playing and substance use problems involved the same types of motivations: to pass time/regulate negative emotion, enhance positive emotion, or balance each type of behavior out (videogame play versus use of a substance). In their other paper, they found that (controlling for the shared variance of problem substance use (caffeine, tobacco alcohol, or marijuana) and problem videogame playing) videogame playing while concurrently feeling the effects of a drug III was uniquely associated with problem substance use, but not with problem levels of videogame playing. That is, it appeared that concurrent activity was fundamentally related to substance use difficulties but not the converse. The final paper in this Special Issue, by Sussman and Sussman [12] revisited the definition of addiction. These authors suggested that cycles of engaging in addictive behaviors to attempt to satiate an appetitive effect that become associated with preoccupation, loss of control and negative life consequences, were the criteria that defined addictive behaviors. They also suggested that there were philosophical concerns regarding the relations of these criteria with each other and with the concept of addiction. Taken together, it is hoped that these 11 papers assist in the arduous task of moving the study of addictive behaviors forward through considering pathways and associations of the many types of behaviors that might encompass, at least in part, the same types of underlying mechanisms. Steve Sussman, Ph.D. Guest Editor References 1. Sussman, S.; Lisha, N.; Griffiths, M. Prevalence of the Addictions: A Problem of the Majority or the Minority. Eval. Health Prof. 2011, 34, 3-56. 2. Sussman, S.; Leventhal, A.; Bluthenthal, R.N.; Freimuth, M.; Forster, M.; Ames, S.L. A Framework for the Specificity of Addictions. Int. J. Environ. Res. Public Health 2011, 8, 3399-3415. 3. Blum, K.; Chen, A.L.C.; Oscar-Berman, M.; Chen, T.J.H.; Lubar, J.; White, N.; Lubar, J.; Bowirrat, A.; Braverman, E.; Schoolfield, J.; et al. Generational Association Studies of Dopaminergic Genes in Reward Deficiency Syndrome (RDS) Subjects: Selecting Appropriate Phenotypes for Reward Dependence Behaviors. Int. J. Environ. Res. Public Health 2011, 8, 4425-4459. 4. Griffin, K.W.; Scheier, L.M.; Acevedo, B.; Grenard, J.L.; Botvin, G.J. Long-Term Effects of Self-Control on Alcohol Use and Sexual Behavior among Urban Minority Young Women. Int. J. Environ. Res. Public Health 2012, 9, 1-23. 5. Freimuth, M.; Moniz, S.; Kim, S.R. Clarifying Exercise Addiction: Differential Diagnosis, Co-occurring Disorders, and Phases of Addiction. Int. J. Environ. Res. Public Health 2011, 8, 4069-4081. 6. Bergmark, K.H.; Bergmark, A.; Findahl, O. Extensive Internet Involvement—Addiction or Emerging Lifestyle? Int. J. Environ. Res. Public Health 2011, 8, 4488-4501. IV 7. Sun, P.; Johnson, C.A.; Palmer, P.; Arpawong, T.E.; Unger, J.B.; Xie, B.; Rohrbach, L.A.; Spruijt-Metz, D.; Sussman, S. Concurrent and Predictive Relationships Between Compulsive Internet Use and Substance Use: Findings from Vocational High School Students in China and the USA. Int. J. Environ. Res. Public Health 2012, 9, 660-673. 8. Kuss, D.J.; Griffiths, M.D. Online Social Networking and Addiction—A Review of the Psychological Literature. Int. J. Environ. Res. Public Health 2011, 8, 3528-3552. 9. Pentz, M.A.; Spruijt-Metz, D.; Chou, C.P.; Riggs, N.R. High Calorie, Low Nutrient Food/Beverage Intake and Video Gaming in Children as Potential Signals for Addictive Behavior. Int. J. Environ. Res. Public Health 2011, 8, 4406-4424. 10. Ream, G.L.; Elliott, L.C.; Dunlap, E. Patterns of and Motivations for Concurrent Use of Video Games and Substances. Int. J. Environ. Res. Public Health 2011, 8, 3999-4012. 11. Ream, G.L.; Elliott, L.C.; Dunlap, E. Playing Video Games While Using or Feeling the Effects of Substances: Associations with Substance Use Problems. Int. J. Environ. Res. Public Health 2011, 8, 3979-3998. 12. Sussman, S.; Sussman, A.N. Considering the Definition of Addiction. Int. J. Environ. Res. Public Health 2011, 8, 4025-4038. Reprinted from Int. J. Environ. Res. Public Health. Cite as: Sussman, S.; Leventhal, A.; Bluthenthal, R.N.; Freimuth, M.; Forster, M.; Ames, S.L. A Framework for the Specificity of Addictions. Int.J.Environ. Res. PublicHealth2011,8,3399-3415;doi:10.3390/ijerph8083399. G Int. J. Environ. Res. Public Health 2011, 8, 3399-3415; doi:10.3390/ijerph8083399 OPEN ACCESS International Journal of Environmental Research and Public Health ISSN 1660-4601 www.mdpi.com/journal/ijerph Article A Framework for the Specificity of Addictions Steve Sussman 1,*, Adam Leventhal 1, Ricky N. Bluthenthal 1, Marilyn Freimuth 2, Myriam Forster 1 and Susan L. Ames 3 1 Departments of Preventive Medicine and Psychology, University of Southern California, California 90032, CA, USA; E-Mails: [email protected] (A.L.); [email protected] (R.N.B.); [email protected] (M.F.) 2 Clinical Psychology, Fielding Graduate University, Santa Barbara, California 93105, CA, USA; E-Mail: [email protected] 3 School of Community and Global Health, Claremont Graduate University, Claremont, California 91711,CA, USA; E-Mail: [email protected] * Author to whom correspondence should be addressed; E-Mail: [email protected]; Tel.: +1-626-457-6635; Fax: +1-626-457-4012. Received: 24 July 2011 / Accepted: 5 August 2011 / Published: 18 August 2011 Abstract: Research over the last two decades suggests that a wide range of substance and behavioral addictions may serve similar functions. Yet, co-occurrence of addictions has only been reported among a minority of addicts. “Addiction specificity” pertains to a phenomenon in which one pattern of addictive behaviors may be acquired whereas another is not. This paper presents the PACE model as a framework which might help explain addiction specificity. Pragmatics, attraction, communication, and expectation (PACE) variables are described, which may help give some direction to future research needs in this arena. Keywords: addiction specificity; PACE model 2 G Int. J. Environ. Res. Public Health 2011, 8 3400 1. Introduction: Addiction as a Biopsychosocial Phenomenon Involving a Range of Different Behaviors For many years, researchers and practitioners have discussed various seemingly irrational behaviors that exhibit patterns of self-destruction similar to drug abuse [1-8]. Indeed, the concept of “addiction” has broadened in scope from referring to only physiologic processes related to drug misuse (pharmacodynamic tolerance and withdrawal) to a more elaborate biopsychosocial syndrome with commonalities across several behaviors. An overarching feature of the addictive process includes compulsively performing a behavior, for example, continuous drug taking, binge eating, gambling or working [2,4,9-14]. During the “addictive process” [2,4,5] initially one may pursue some course of action for appetitive effects such as pain reduction, affect enhancement, arousal manipulation, or fantasy. Over repeated engagement in the behavior, the individual becomes intensely preoccupied with the behavior despite diminishing appetitive effects [15,16]. Subsequently, the individual, if desiring to control or stop the behavior, experiences subjective loss control over when the behavior is initiated, how it is manifested, or when it will stop. Finally, one incurs negative consequences (e.g., social, role, physical, emotional) while continuing to engage in the self-defeating behavior. Stopping the behavior becomes difficult for several reasons, including having a lack of awareness of the “stimuli” or triggers that influence the behavior and the cognitive salience of immediate gratification relative to delayed adverse effects. That is, the behavior becomes increasingly more automatic and less under one’s control-ability [17-20]. At this point, the individual also may fear having to cope with day-to-day perceived stress and other life experiences upon cessation (possibly due to accumulation of addiction-related consequences, or having to endure “raw” emotional experiences without concurrent self-medication [5]), as well as having to suffer withdrawal-related phenomena [4,11,14]). Various substance and process/behavioral addictions appear to be intricately connected in terms of etiology, patterns of behavior, and consequences [12,21]. 1.1. Patterns of Addiction Co-Occurrence While it is not entirely clear what differentiates addictive-prone from non-addictive prone behaviors [22], Sussman, Lisha and Griffiths [14] identified 11 relatively common behaviors that appear to have addiction propensity (tobacco use, alcohol use, illicit drug use, binge eating, gambling, internet use, love, sex, exercise, work, and shopping). That article reported the prevalence and co- occurrence of these behaviors based on a systematic review of the literature. Data from 83 studies (each study n equal to or greater than 500 subjects) was presented and supplemented with smaller-scale data. The authors noted a 23% average co-occurrence among the 11 addictions (with a range from 10% to 50% overlap among 110 pairs of co-occurrence examined), and determined that approximately 50% of the U.S. adult population has suffered from signs of some type of addictive behavior over a 12-month period, controlling for co-occurrence. Although there are some methodological limitations [14], their findings suggest that there is marked variability in the pattern of addiction co-occurrence. As examples, addictions to cigarettes, alcohol, and illicit drugs are highly associated with each other and with sex and love addiction, which also are highly associated with each other. In addition, gambling addiction is strongly associated with cigarette smoking addiction but not as much with illicit
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