studies on the efficacy of essential fatty acid on spontaneous alopecia and pruritus in dog ...

112 Pages·2017·13.81 MB·English

STUDIES ON THE EFFICACY OF ESSENTIAL
FATTY ACID ON SPONTANEOUS ALOPECIA
AND PRURITUS IN DOG
)I Th£sis
Su6mitted to the
of
West CBenea{ Vniversity )lnima{ aruf Pisfzery Sciences
of of
In partia{f u(fillment tlie requirement for the degree
of
9rtaster Veterinary Science
In
VETERINAR\, MEDI£INE!t t:THI£S
A JURISI·RUDEN£E
By
SUMANASADHUKHAN
B.V.Se. & A.H.
DEPARTMENT OF
VETERINARY MEDICINE, ETHICS AND JURISPRUDENCE
FACUL1Y OF VETERINARY AND ANIMAL SCIENCES
WEST BENGAL UNIVERSITY OF ANIMAL AND FISHERY SCIENCES
37 & 68, KSHUDIRAM BOSE SARANI, KOLKATA-700 037
WEST BENGAL, INDIA
2013
1Jeaicatea
to
:lvly'Be{ovea
Parents
DEPARTMENT OF VETERINARY MEDICINE,
ETHICS AND JURISPRUDENCE
WEST BENGAlIINMRSITY OF 4NIM41 AND FISHERY S(IEN(ES
FACULTY OF VETERINARY AND ANIMAL SCIENCES
37 & 68 KSHUDIRAM BOSE SARANI, KOLKATA-700 037
WEST BENGAL
Im
l
IllIm)
•
Prof.(Dr.) Amalendu Chakrabarti
M.V.Sc., Ph.D.
Former Dean ofF/O-VAS
Former Head of Dept. VMEJ Date:.. ..... .•
CER'I'IFICATE
This is to certify tfiat tfie thesis entit{etf "stwfies on tlie
efficacy of essential fatty acicf on ~ontaneous afopecia ami
pruritus in dog" sUbmitted fly Sumana Satffiukfian, in partia{
fu(fi{(ment of tile requirem.ents fOY the ''Degree of Master of
Yeterinary Science in Yeterinary :Medicine, 'Etfiics and
Jurisprudence' of tfie West 13enga{ 'University of :4.nima{ ana
:fishery Sciences, is the faithfu{ ana 60naficfe researcfi work carried
out unaer my personaf supervision andg uidance. The resu{ts of tlie
investigation reyorted in the thesis have not so far fleen su6mittea
for any otfier Degree or Vip{oma.
'lfie assistance ana he[p recelvea during the course 0/
investigation fiave been dU(V acknowfedjjecf.
Dated, Kolk.lla.
(Prof. A NDU CHAKRABARTI)
'I"lle -!f'~ {[}JI.201a Chairman,
Advisory Committee
APPROVAL OF EXAMINERS FOR THE AWARD OF THE
DEGREE OF MASTER OF VETERINARY SCIENCE IN
VETERINARY MEDICINE, ETHICS AND JURISPRUDENCE
We, the undersigned having been satisfied with the performance of
Sumana Sadhukhan in the viva-voce Examination, conducted today,
the ~ ...... 2013. recommend that the thesis be accepted
for the award of the degree of Master of Veterinary Science in
Veterinary Medicine, Ethics and Jurisprudence.
NAME SIGNATURE
..
az~
1. Prof. Amalendu Chakrabarti Chairman,
M.V.Sc., Ph.D. Advisory Committee ,
.~~
'" External Examiner
3. Prof. N. R. Pradhan Member,
M.V.Sc., Ph. D. Advisory Committee
~
4. Prof. S. Sarkar Member,
M.V.Sc., Ph. D. Advisor Committee ................ ,
"0("
G!'~
5. Dr. C. Lodh Member,
M.V.Sc., Ph.D. Advisory Committee . ........................
6. Dr. S. Batabyal Member,
M.V.Sc., Ph.D. Advisor Committee
JU this important juncture of my research, J woul£( aRe to
express my lieartfe{t gratttude to a[(yersonaCities, wlio either
direct(\f or indirect{y ftefped me towards tfie successJu{
comy(etion of my thesis.
J wou{{{ aRe to taRe tliis ~pyortunity to convey my sincere
and lieartfuI tftanks to my cogent advisor, Prof
and~prescriytive
(1Jr.) Ama{enau Chakra6arti, Veyartment of 'Veterinary
_'Medicine, 'Ethics and lurisyrudence, :facufty of Yeterinary ana
:4.nima{ Sciences, West 'Benga{ 'University of Anima{ ana
:fishery Sciences, for his exyert guiaance, constant insyiration,
who{ehearted' co-,?peration, constant suyervision, ana vafua6fe
suggestions for carrying out the research work.
J am extremefy gratefuf to Prof C. S. Chakraborty, 'Vice
Cfiance{{or, Prof To X . .1vtonda{, Dean, J'acu(ty ofYeterinary ana
.J\nima[ Sciences, Prof. P. Biswas, 'Registrar, West Benga[
'University of Animal" ana :Fishery Sciences for giving me tfie
oyportunity for carrying out my thesis worR without any
problem.
J wish to extena my stncere gratitude to Prof ·N. 'R.
Pradfian, Prof S. Sarkar and 'Dr. C. Loaft, Senior Lecturer,
'Department of Yeterinary Jv1eaicine, 'Etftics ana lurisprudence,
:Facu{ty of Yeterinary and- Anima{ Sciences, West 'Bengaf
'University of Animaf and :Fishery Sciences ana member,
Advisory committee for tfieir co-oyeration ana constant
encouragement auring entire yeriod '?f my thesis worR.
I afso express my sincere thanks to Dr. S. 'Batavyf, Senior
Lecturer, Veyartment of lIeterinary 'Biochemistry, :FacuCty of
lIeterinary ana .Jtnima{ Sciences, 'West 'Benea{ llniversity of
.7tnima{ ana :Fishery Sciences ami memver, .Jtavisory committee
for liis active liefp ana selft:ess suyyort aurine my researcfi.
I am sincere{y ovfieea ana inaevtea to Prof C. (julia, Dr.
11. 'B isw as, Senior Lecturer, am;[ Dr. 'P. S. lana, .7tssociate
yrofessor, Veyartment of lIeterinary 'Eyiaemio{ogy and
Preventive Mdicine, :FacuCty of lIeterinary ana .7tnima{
Sciences, 'West 'Benea{ l1niversity of .Jtnima{ ana :Fisliery
Sciences for their keen he[p, va{uav{e sUfJgestions aurine the
entire perioa of this work.
I wish to extena my grateJufness ana owe my indevtness
anar espect to Vr. 11. Sarkar, .7tssociate yrofessor, Department of
.Jtnima{ (jenetics ana 'Breeding, :Facu{ty of lIeterinary ana
.Jtnima{ Sciences, 'West 'Rengaf l1niversity of .Jtnimaf ana
:Fishery Sciences for his kina liefp am;[ innate interest w"hich
ftefpea to comy{ete the thesis programme smoothfy ana timefy.
:My sincere thank.s to Vr. (gurucharan Vatta ana Dr.
Ravindra Natfi (ghosfi, Jtsst. Director, (gavt. of 'West 'Renea{ for
tfieir keen he[p and constant encouragement throueflOut the
stuay.
I wou{a fike to convey my thanks to my seniors 'Dr .
.Jtnnayurna Singha, Vr. Nayan 'Batuf, 'Dr. Triytenau J{ar, 'Dr.
Prasun :M.ukfierjee, 'Dr. Sliamya Chakravorty, Vr. Surojit Vas,
'Dr. Suni{ Xumar; juniors .Jtvanisfi, Samarjit, Supra6fia,
.7t6um~
Nivecfita ana year-mates Madfiurima, Sfiu6liamoy, Suyama
ana 'Waa for tfieir active lie(p ana constant encouragement
tfirougliout tfie stuay.
I would a~e to tfian~ 5tsfW~e da ana otlier non-teaching
staff of aog-ward, Jl.yur6a cia and otfier non-teaching staff of
'Deyartment of 'Veterinary 'Biochemistry and the non-teaching
staffs of 'Deyartment of 'Veterinary :Medicine, Ttfiics and
Jurisyrudence for their assistance and active he(p tfiroughout
tfie stuay.
I wish to exyress my syecia{ tlianks to my room-mates
di, 'Diya; brothers Indranil; .Jtrinda111, Sougat,
'E~antika ~oura6,
.:Ajgar aa ana sisters .Jtjuswita, Susmita, Sohe[i, dl for
'Priyan~a
their constant encouragement througfwut tfie study.
I wou{a to convey my rove to my sister 'Romi for lier
a~e
whore heartea suyyort and constant encouragement auring my
thesis
wor~.
It would 6e incomy[ete without syecia{ mention of my
ensem6{e 'Rakesh wliose se[f[ess aedication, cheerfu.[ insyiration,
menta[ support, va{ua6fe fie[p ana constant encouragement
me to reach at aestination.
ma~es
J'ina{[y, :My yrofound inae6tness to my 6e[oveay arents for
their rent{ess 6[essings, rove, great sacrifice and heartfert
affection throughout my fife.
'Date" 'Befeachia,
Xo~ata c5\-\~ ·~dkk~~ .
'11i e_ __"_;f_ ~___ __0_ ~\ _-__I ___ J 2013 (Sumana SadJiuRlian)
CONTENTS
Chapter No. Particulars Page No.
Chapter 1 : Introduction 1 - 3
Chapter 2 : Review of the Literature 4 - 36
Chapter 3 : Materials and Methods 37 - 43
Chapter 4: Result and Discussion 44 - 60
Chapter 6 : Summary and Conclusion 61 - 63
Chapter 7 : Future Scope of Research 64
...
Chapter 8 : Bibliography
1 - XV111
E1STOFFIGURES AND TABlJEL{j,
Figure
No. Subject
1 Photograph showing collection of blood sample.
2 Photograph showing collection of skin scrap.ing.
3 Photograph showing test tubes with reagents while test
was done for estimation of cholesterol.
4 Photograph showing test tubes with reagents while test
was done for estimation of HDL.
5 Photograph showing test tubes with reagents while test
was done for estimation of triglyceride.
6 Picture showing the bar diagram depending on type of
alopecia.
7 Picture of pie chart depending on severity of pruritus.
8 Picture showing the bar diagram depending on age group.
9 Picture showing the bar diagram depending on sex.
I
Photographs of a. The dog with generalised alopecia and
moderate pruritus (++) before treatment.
10a-b b.The same dog without alopecia and reduced pruritus(+)
after treatment with Velcote.
Photographs of a.The dog with discrete alopecia and
severe pruritus (+++) before treatment.
l1a-b b.The same dog after treatment with Velcote without
alopecia and no pruritus.
Photographs of a. The dog with discrete alopecia and mild
12a-b pruritus (+) before treatment.
b.The same dog after treatment with Ve1cote with
resurgence of hair and no pruritus.
Photographs of a. The dog with discrete alopecia and
13a-b moderate pruritus (++) before treatment.
b.The same dog without alopecia and no pruritus after
treatment with Rice-bran oil.
Photographs of a. The dog with discrete alopecia and
14a-b moderate pruritus (++) before treatment
b. The same dog no alopecia, no pruritus and increased
glossiness after treatment with Rice-bran oil
Photographs of a. The dog with discrete alopecia and
lSa-b moderate pruritus (++) before treatment.
b.The same dog no alopecia, no pruritus and increased
glossiness after treatment with Rice-bran oil.