Studies on Pediatric Disorders PDF
Preview Studies on Pediatric Disorders
Oxidative Stress in Applied Basic Research and Clinical Practice Hirokazu Tsukahara Kazunari Kaneko Editors Studies on Pediatric Disorders Oxidative Stress in Applied Basic Research and Clinical Practice Editor-in-Chief Donald Armstrong For further volumes: http://www.springer.com/series/8145 Note from the Editor-in-Chief All books in this series illustrate point-of-care testing and critically evaluate the potential of antioxidant supplementation in various medical disorders associated with oxidative stress. Future volumes will be updated as warranted by emerging new technology, or from studies reporting clinical trials. Donald Armstrong Editor-in-Chief Hirokazu Tsukahara (cid:129) Kazunari Kaneko Editors Studies on Pediatric Disorders Editors Hirokazu Tsukahara Kazunari Kaneko Department of Pediatrics Department of Pediatrics Okayama University Graduate School of Kansai Medical University Medicine, Dentistry and Pharmaceutical Hirakata-shi Sciences Osaka , Japan Okayama , Japan ISSN 2197-7224 ISSN 2197-7232 (electronic) ISBN 978-1-4939-0678-9 ISBN 978-1-4939-0679-6 (eBook) DOI 10.1007/978-1-4939-0679-6 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2014937525 © Springer Science+Business Media, LLC 2014 T his work is subject to copyright. 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Printed on acid-free paper Humana Press is a brand of Springer Springer is part of Springer Science+Business Media (www.springer.com) Contents Part I General Topics 1 Oxygen and Oxidative Stress in the Newborn ...................................... 3 Ola Didrik Saugstad 2 Reactive Oxygen Species and Nitric Oxide in Vascular Function ...... 15 Michael S. Wolin 3 Nitrite-Dependent Nitric Oxide Production Pathway: Diversity of NO Production Systems ..................................................... 35 Hideo Yamasaki, Naoko S. Watanabe, Jon Fukuto, and Michael F. Cohen 4 Nitric Oxide and Endothelial Dysfunction ........................................... 55 Eisei Noiri and Kousuke Minami 5 Multifunctional Roles of Nitric Oxide (NO) in Neurons ..................... 71 Tayo Katano and Seiji Ito Part II Basic Science Topics 6 Oxidative Stress Biomarkers: Current Status and Future Perspective ........................................................................... 87 Hirokazu Tsukahara 7 Urinary L-Type Fatty Acid-Binding Protein as a New Renal Biomarker ..................................................................... 115 Tsuyoshi Oikawa and Takeshi Sugaya 8 Rapid Diagnostic Tests for Oxidative Stress Status ............................. 137 Kazunari Kaneko 9 Analytical Procedures for Nitrative/Nitrosative Stress ........................ 149 Masayuki Kubo and Keiki Ogino v vi Contents 10 An Animal Model of Citrin Defi ciency, the Citrin/Mitochondrial Glycerol 3-Phosphate Dehydrogenase Double-Knockout Mouse ............................................. 159 Takeyori Saheki 11 Antioxidant Supplementation and Therapies ...................................... 183 Varadarajan Sudhahar and Tohru Fukai 12 Edaravone Therapy: From Bench to Bedside ...................................... 211 Toru Yamashita and Koji Abe 13 The Use of Melatonin against Oxidative Stress in Pediatric Disorders ............................................................................. 219 You-Lin Tain and Li-Tung Huang 14 Thioredoxin Therapy: Challenges in Translational Research ............ 233 Masato Yashiro, Hirokazu Tsukahara, and Tsuneo Morishima Part III Clinical Topics 15 Allergic and Immunological Disorders ................................................. 255 Akihiro Yachie 16 Oxidative Stress in Kawasaki Disease ................................................... 271 Tomoyo Yahata and Kenji Hamaoka 17 Environmental Pollution and Health Consequences............................ 283 Pavel Rossner Jr. and Radim J. Sram 18 Oxidative Stress in Infl ammatory Bowel Disease ................................. 301 Tomohisa Takagi, Kazuhiko Uchiyama, and Yuji Naito 19 Genetic Disorders and Oxidative Stress (Especially Chronic Granulomatous Disease) ...................................... 315 Shoji Tsuji and Kazunari Kaneko 20 Growth, Puberty, and Nutritional Disturbances .................................. 329 Valentina Chiavaroli, Aurelia Guarini, Francesco Chiarelli, and Angelika Mohn 21 Hematologic Disorders ........................................................................... 349 Stephen Rogers, Manuel Silva, and Allan Doctor 22 Infectious and Infl ammatory Disorders ................................................ 371 Hirokazu Tsukahara, Masato Yashiro, Yoshiharu Nagaoka, and Tsuneo Morishima 23 Oxidative Stress in Inherited Metabolic Diseases ................................ 387 Hironori Nagasaka, Hirokazu Tsukahara, and Takashi Miida Contents vii 24 Neurological Disorders (Especially Developmental Brain Disorders) ...................................................................................... 405 Masaharu Hayashi, Rie Miyata, and Naoyuki Tanuma 25 Oxidative Stress in Kidney Diseases ...................................................... 421 Kazunari Kaneko 26 Trauma ..................................................................................................... 441 Fukashi Serizawa, Eric Patterson, Gediminas Cepinskas, and Douglas D. Fraser 27 Oxidative Stress and Pulmonary Vascular Disorders .......................... 457 Christine M . Gross, Saurabh Aggarwal, Ruslan Rafi kov, and Stephen M. Black Index ................................................................................................................. 481 Contributors Koji Abe , M.D., Ph.D. Department of Neurology , Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences , Okayama , Japan Saurabh Aggarwal T he Pulmonary Disease Program, Vascular Biology Center, Georgia Regents University , Augusta , GA , USA Stephen M . Black , Ph.D. The Pulmonary Disease Program, Vascular Biology Center , Georgia Regents University , Augusta , GA , USA Gediminas Cepinskas , D.V.M., Ph.D. C entre for Critical Illness Research, London , ON , Canada Francesco Chiarelli Department of Pediatrics , University of Chieti , Chieti , Italy Valentina Chiavaroli Department of Pediatrics , University of Chieti , Chieti , Italy Michael F. Cohen , Ph.D. Department of Biology , Sonoma State University , Rohnert Park , CA , USA Allan Doctor , M.D. D epartments of Pediatrics and Biochemistry, W ashington University in Saint Louis, School of Medicine , St. Louis , MO , USA Douglas D. Fraser , M.D., Ph.D. Pediatric Critical Care Medicine, Translational Research Centre, Children’s Health Research Institute and Centre for Critical Illness Research, Western University, London, Ontario, Canada Tohru Fukai , M.D., Ph.D. D epartments of Medicine (Section of Cardiology) and Pharmacology , Center for Cardiovascular Research, University of Illinois at Chicago , Chicago , IL , USA Jon Fukuto , Ph.D. Department of Chemistry , Sonoma State University , Rohnert Park , CA , USA Christine M. Gross T he Pulmonary Disease Program, Vascular Biology Center, Georgia Regents University , Augusta , GA , USA ix
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