Table Of Content

Author Index Abbondanza, C., 4 Desai, U. R., 170 Jalaludin, S., 387 Abdullah, S. H., 387 Di Salle, E., 527 Janssen, G. A., 351 Acosta, C. K., 205 Djerassi, C., 508 Jaskoll, T., 400 Adlercreutz H., 301 Dmitrenok, A. S., 508 Joseph-Nathan, P., 396 Akanni, O. A., 234 Drayer, N. M., 495 Anjo, T., 540 Durell, S., 370 Antoine, P. A., 335 Dwivedy, I., 69 Kaleczyc, J., 466 Armanini, D., 611 Dwyer, T. M., 305 Kalinin, V. I., 508 Armetta, I., 4 Kalin, M., 291 Kapustina, I. I., 508 Asano, N., 40 Axelson, M., 119 Ebrahimian, S., 414 Kasahara, N., 551 Egorov, A. M., 547 Katzenellenbogen, J. A., Eyssen, H. J., 351 Kawai, C., 472 Bakos, T., 115, 185, 220 Ezell, E., 260 Kaye, A. M., 126 Banerjee, S., 484 Kermici, M., 429 Banos, G., 407 Khan, M. N., 387 Baran, D. T., 491 Fantin, G., 524 Kieslich K., 278 Bartok, M., 533 Faure, A., 335 Kim, H. K., 205 Bague, A., 429 Fernandez, G. J. M., Kirk, D. N., 59 Belanger, A., 29 Fiet, J., 29 Kirschenbaum, A., 439 Belanger, B., 29 Filthuth, P. H., 429 Kiss, R., 64 Bender, W. H., 106 Fogagnolo, M., 524 Kitajima, M., 215 Bermudez, E., 225 French, A. N., 157 Kornel, L., 564, 580 Billaudel, J. L., 335 Futo, L., 64 Kraan, G. P. B., 495 Blackwell, L. F., 452 Krieg, Jr., R. J., 126 Boguslavsky, V. M., 508 Krieger, N., 112 Garcia-Martinez, C., 396 Booth, A., 348 Garcia-Mondragon, J., 457 Krischenowski, D., 278 Bradlow, H. L., 215 Gavrilova, E. M., 547 Kubota, T., 215 Bremner, J. B., 387 Giordano, F., 134 Kudo, H., 551 Briatico, G., 527 Kumar, V. P. S., 518 Glasier, M. A., 478 Brown, K. A., 178 Glaz, E., 64 Kurosawa, T., 52 Brown, T. J., 13 Godlray, D., 126 Kuwa, K., 551 Brueggemeier, R. W., 414 Gomez-Sanchez, C. E., 384 BBuukcuhsaongalnu,, TC.. ,A .,1 126 21 Gondos, G., 533 LaBella, F. S., 518 BBuuzszseotnt,i , R.F .,H .5,2 73 51 GGGoortevogi,on rdyaJ,.n, , R1.4M,8. ,, 2 63861 27 8 LLLaaetjgiiafs,n, , SN..M .A H..,V, . ,5 398 573 6 Gros, E. G., 181 Lemini, C., 457 Callard, G. V., 87 Gunter, A., 320 Levashov, A. V., 547 Cameron, K. J., 230 Levine, A. C., 439 Carroll, M. A., 573 Hadd, H. E., 445 Lin, F.-T., 106 Cassorla, F., 126 Hammond, G. L., 275 Ling, Y., 518 Castro, D., 457 Hanninen, E., 330 Li, P.-K., 106 Chang, F. C., 148, 362 Hayashi, T., 580 Litasova, E. E., 536 Chen, H.-H., 414 Llanos, M. N., 314 Herz, J., 260 Chen, S.-M., 35 Lokos, M., 115, 185, 220 Hirata, M., 74 Chetrite, G., 209 Hobkirk, R., 478 Longo, A., 527 Chigurupati, R., 580 Hochberg, R. B., 13 Luttge, W. G., 400 Collins, K., 87 Hodge, J. D., 178 Cordeiro, M. L., 508 Holick, M. F., 462 Cova, U., 524 Horhold-Schubert, C., 320 Maalouf, N., 621 Cozza, E. N., 384 Hoyte, R. M., 13 MacLusky, N. J., 13 Cruz—Almanza, R., 457 Huang, Y.-S., 35 Mahara, R., 52 Cuevas, M. E., 87 Mahato, S. B., 79, 484 Cummins, C., 245 Makarieva, T. N., 508 Ichihara, K., 472 Mak, M., 220 Iguchi, K., 410 Malozowski, S., 126 Dabbs, J., 348 lida, T., 148, 362 Mandoki, J. J., 407, 457 Dancsi, A., 220 Ikegawa, S., 52 Manisundaram, B., 580 Darwin, H., 621 Iki, K., 282 Mannaerts, G. P., 351 Davioud, E., 141 Illera, J. C., 324 Marandici, A., 153 de Falco, A., 4 Illera, M., 324 Markaverich, B., 268 De la Pena, A., 407 Ito, Y., 40 Marples, B. A., 234 del Carmen Vila, M., 384 Ivanova, L.N., 536 Marquet, A., 141 Delbancut, P. A., 335 Izaguirre, R., 407 Martella, L., 611 Steroids, 1993, vol. 58, December 635 Author Index Martino, D. M., 106 Quilley, C. P., 573 Templeton, J. F., 518 Matsuki, Y., 540 ‘Vit, ¥., 35 Matsuzaki, H., 423 Tinnikov, A. A., 536 Max, S. R., 357 Racz, K., 64 Tohma, M., 52 Mazumder, I., 79 Radwanska, E., 605 Tonda, K., 74 Mazur, A., 348 Rajkumar, K., 100 Toth, M., 64 McCabe, R. D., 305 Rao, M., 170 Trivedi, G. K., 170 McGiff, J. C., 573 Rao, P. N., 205 Tuckey, R. C., 230 Medici, A., 524 Ray, R., 462 Medici, N., 4 Ray, S., 69, 462 Meehan, W. P., 621 Ren, M., 439 Melnick, M., 400 Revelli, G. A., 181 Uomori, A., 74 Mendoza-Patino, N., 457 Reyes-Lopez, J., 396 Urabe, M., 209 Migliuolo, A., 134 Rockwell, J. C., 491 Mikola, H., 330 Roder, H., 370 Miyamori, I., 282 Ronco, A., 314 Valladares, L. E., 314 MMoolki,n arWi., MA.., M.1,1 2 4 RRoossee,n thSa.l,, 46J2. , 566 vvaann Wdeere ,M oKl.e n,T. , J.4 9C5. , 495 Moncharmont, B., 4 Rubio-Poo, C., 457 van Leusen, D., 495 Monder, C., 153 Van Baelen, H., 275 Moore, K. S., 370 Saad, M. F., 621 Varga, I., 64 Mori, T., 551 Saegusa, K., 540 Viger, A., 141 Morris, D. J., 24, 59 Sakai, D. D., 400 Vincze, I., 115, 185, 220 Mousavi, Y., 301 Sakamoto, S., 551 Vingler, P., 429 Mukherjee, E., 484 Salim, S., 387 Viscardi, R. M., 357 Mutsumi, A., 40 Sassa, S., 551 Voigt, B., 320 Scali, M., 611 Volford, J., 115 Nagasawa, H., 551 Schambel, P., 141 Nagel, G. T., 495 Schroder, M. H., 59 Nambara, T., 148, 362, 540 Seo, S., 74 Walker, B. R., 614 Nandedkar, T. D., 379 Sergev, O., 64 Wang, K., 225 Naumann, H., 320 Shimura, H., 410 Wang, Z.-Q., 35 Nelson, W. A., 580 Shoda, J., 119 Wehrli, S. L., 370 Nichols, N. R., 400 Sica, D., 134 Weisman, Y., 126 Nigro, V., 4 Silva, G., 457 Welch, M. J., 157 Nishida, S., 148 Silvan, G., 324 Whorwood, C. B., 614 Singh, A. K., 69 Niwa, T., 148, 362 Wilson, S. R., 157 Numazawa, M., 40, 423 Singh, M. M., 69 Wittman, G., 533 Nufiez-Smith, M., 178 Sjovall, J., 119 Wolthers, B. G., 495 Smith, L., 260 Wong, G. Y., 215 Smith, M. J., 305 Wu, Y., 452 Orlowski, J. M., 580 Somjen, D., 126 Wyrzykowski, Z., 466 Or, 3: €.. 533 Sorensen, A. M., 491 Osborne, M. P., 215 Souness, G. W., 24, 59 Oshibe, M., 423 Sridharan, R., 170 Stewart, P. M., 614 Yamada, Y., 410 Stonik, V. A., 508 Yang, Z., 410 Parmentier, G. G., 351 Sugiura, Y., 551 Yatsimirskaya, E. A., 547 Pasqualini, J. R., 209 Sundell, A.-C., 330 Ye, Y.-H., 35 Pavlova, I. P., 536 Suto, A., 215 Yongue, B. G., 594 Pedrini, P., 524 Sutter, C. J., 335 Yoshimura, T., 52 Phillips, G. B., 286, 554 Suzuki, E., 540 Young, B. L., 106 Piccialli, V., 134 Suzuki, S., 551 Pillai, R., 106 Porzel, A., 320 Power, S. G. A., 275 Takeda, K., 74 Zampollo, V., 611 Pratesi, C., 611 Takeda, R., 282 Zasloff, M., 370 Pruche, F., 429 Takeda, Y., 282 Zavala, E., 457 Pryor, W. A., 225 Tamaru, T., 362 Zennaro, C. M., 611 Przybylska, B., 466 Tambe, S. S., 379 Zumoff, B., 196 Puca, G. A., 4 Telang, N. T., 215 Zumoff, B., 291 636 Steroids, 1993, vol. 58, December Subject Index Breast cancer, 196 Breast cancer risk, 196 Bridge, 330 A-aromatic pregnenes, 185 Bromosteroids, 170 A and B rings, 170 Brown algae, 178 ACE inhibition,566, 588 Buame, 407 Acetoxylation, 52 Butanolide, 234 Acid, 148 Butolame, 457 ACTH, 29 Adaptation, 305 C NMR spectra of azasteroids, 13 Addition reaction, 1, 4, 423 C-19 steroids, 29 Adrenal tissue and aldosterone, 282 C-ring unsaturated steroids, 396 Adrenocortical adenoma cells (human), 64 Ca?* transport, 580 Affinity, 275 Calcium channels, 305 Affinity ligands, 268 Calcium handling, 335 Affinity of transcortin leuven, 275 Calvaria cells, 126 Alcaligenes recti, 79 Cancer, 245 Aldosterone, 305, 611 Carbenoxolone, 24 Aldosterone inhibitor, 64 Cardiac arrest, 536 Aldosterone-producing adenoma, 282 Cardiac glycoside receptor, 518 Aldosterone stimulation, 384 Catechol estrogen, 540 Aldosterone stimulation, hemin, 384 Catechol O-methyltransferase, 540 Algae, marine sterols, 178 Chemical synthesis, 40 Allo bile acids, 148 Chemosuppression, 215 Amino acids, 35 Children, 536 Aminoestrogens, 407 Chiral reduction, 533 Aminoestrogens, 178-, min 457 Chloro-19-norpregna-4, 17(20),20-trien-3-one, 220 Anchorage-independent growth, 215 Cholestanoic acids, 351 Androgen receptor ligand, 13 Cholesterol, 74, 178, 225, 260 Androgen analog, 13 Cholesterol distribution, 178 Androgenized female rats, 126 Cholesterol in marine algae, 178 Androgens, 439 Cholesterol, [3Beta-17 O], 260 Anesthetic, 112 Cholesterol side-chain cleavage, 230 Angiotensinogen, 594 Cholesterol ozonation products, 225 Animal models, 196 Cholic acid, 484 Antibacterial, 370 Cloning-efficiency, 215 Anticarcinogen, 301 Conformation analysis, 170 Anticoagulant effect, 457 Conjugate, 547 Antiestrogens, 209, 215 Contraceptives, 69 Antiestrogens, effects in fetal guinea pig cells, 209 Coronary disease, 286 Antimicrobial, 370 Coronary heart disease and sex hormones, Antimineralocorticoid, 24 Corticosteroid biosynthesis (human), 64 Antral follicles, 379 Corticosteroid inhibitor, 64 Arachidonic acid, 573 Corticosteroid-binding globulin, 275, 536 Aromatase, 40, 414 Corticosteroid-binding globulin/transcortin, Aromatase inhibitor, 423, 527 Corticosteroid intermediates, 396 Arthrobacter simplex, 484 Corticosteroid responsiveness, 400 Assay, 462 Corticosteroids, 495 Atherosclerosis, 605 Corticosterone, 153 Axinyssa genus, 410 Cortisol, 29 Axinysterol, 410 Cortisol inhibitor, 64 Azahomoestranes, 69 Cortisol metabolism, 614 Azasteroids, 69, 181 Corynespora melonis CBS 16260, 278 Azasteroids, synthesis of, 181 Cosegregation, 594 Cunninghamella achinulata, 320 Bacterial transformation, 79 Cytochrome P450, 573 B, 8-, 278 Cytochrome P450,.., 230 B, 11-, 278 Bile acid 52, 79, 351, 362 D-homoaromatic gonenone, 220 Bile acid biosynthesis, 119 D-homoaromatic steroids, 220 Binding affinity, 35 Danazol, 551 Biosynthesis, 74 Dehydration of gem hydroxyethynylsteroids, 220 Biosynthesis of sea cucumber sterols, 508 Dehydration of 17a—ethynyl steroids, 220 Biosynthesis of sea cucumber triterpenoids, 508 Dehydrocorticosterone, 11-, 24 Biotransformations, 320 Dehydrogenase/176-dehydrogenase, 429 Birch reduction of A-aromatic pregnenes, 185 Deuterium labeling, 119 Body weight, 348 Diagnosis, 245 Brain, 112 Diaphyseal bone, 126 Brassinosteroids, 320 Difluoroandrost—4—ene—3,6,17-trione, 19,19-, 40 Breast tumor imaging, 157 Digital autoradiography, 429 Steroids, 1993, vol. 58, December 637 Subject Index Dihydrotestosterone, 29, 126 Gonadal steroids, 126 Dihydrotesterone, perinatal modulation, 126 Green algae, 178 Dihydroxy-3-keto-58-cholanoic-24-oic acid, 7, 12-, 524 Guaiacol estrogen, 540 Dihydroxy-Sa-cholanoic acids, 3,6—, 362 Guinea pig, 209, 478 Dihydroxycholesterol, (22R)-20a,22-, 230 Guyton’s hypothesis, 588 Dihydroxyprogesterone, 88, 17a—, 278 Dihydroxyvitamin D,;, la, 25-, 462, 491 H NMR spectra of azasteroids, 181 Dihydroxyvitamin D, receptor, la, 25—, 462 H-2 congenic mice, 400 DNA synthesis, 551 Haloarylestradiol, 245 DNPH Derivatization, 225 Haloestradiol, 16, 245 Haloethynylestradiol, 245 ELISA, 324 Halovinylestradiol, 245 Enamine functionality, 225 Heart disease (coronary) and sex hormones, 286 Endometrium, 551 Heat shock proteins, 400 Enzyme inhibition, 153 Hemin, 384 Enzyme-mediated inactivation, 414 Hep-G2, 301 Enzymeimmunoassay, 324 Hepatocellular cancer, 301 Epi-sarsasapogenin, 387 High-performance liquid chromatography, 74 Epi-smilagenin, 387 Hormone-dependent, 106 Epibrassinolide, 24-, 320 HPLC, 362, 495 Epicastasterone, 24—, 320 Human chorionic gonadotropin, 314 Epidemiology, 196 Human mammary carcinoma cells, 215 Epididymis, 472 Human mammary tumor cells, 215 Epidioxyergosta—6,22,25—trien—38-ol,Sa—,8a—, 410 Hydration of ethynyl group, 185 Epitope mapping, 4 Hydroxy-3-keto-58-cholanoic-24-oic acid, 7-, 524 Essential hypertension, 611 Hydroxy-3-keto-58-cholanoic-24-oic acid, 12-, 524 Estra-1,3,5(10)-trien-17-one-3-sulfonamide, 106 Hydroxy-3-oxo-4-cholesten-27-acid, 7a-, 119 Estradiol, 100, 126, 286, 301, 324, 407, 466 Hydroxy-Sa-pregnanes, 148-, 518 Estradiol, perinatal modulation, 126 Hydroxy-Sa-pregnan-20-one, 3a-, 112 Estradiol and progesterone, 466 Hydroxy-24-epibrassinolide, 128, 320 Estradiol biotransformation, 215 Hydroxy-5-oxo-5,6-secocholestan-6-al, 3B-, 225 Estradiol and coronary heart disease, 286 Hydroxy-24-epicastasterone, 128, 320 Estradiol metabolism, 215 Hydroxy-Sa-cholanoic acids, 6-, 362 Estriol, 452 Hydroxycholesterol, (22R)-22-, 230 Estriol 16- and 17-glucuronides, 452 Hydroxylated 5-cholesten-27-oic acids, 119 Estrogen, 245, 478 Hydroxylated 4-cholesten-3-ones, 119 Estrogen hydroxylation, 196 Hydroxylation, 6a, 495 Estrogen therapy, 196 Hydroxylation, 7a-, 119 Estrogen replacement therapy, 196 Hydroxylation, 21-, 185 Estrogen in fetal guinea pig cells, 209 Hydroxylation, 128-, 320 Estrogen receptor, 4, 35, 157 Hydroxylation, l6a, 196 Estrogenic effect, 457 Hydroxysteroids, deuterium-labeled, 27-, 119 Estrogens, 69, 196, 209, 234, 605 Hydroxysteroids, 27-, 119 Estrone sulfate, 209 Hydroxysteroid dehydrogenase, 118-, 614 Estrone sulfate, transformation in fetal cells, 209 Hypertension, 566, 594, 605, 614, 621 Estrone sulfatase, 106 Hypothermia, 536 Ethisterone trifluoracetate, 220 Ethyl-21-hydroxy-3-methoxy-19-norpregna-3,5-dien-20-one, 11 '5}-Jabeled androgen, 13 Ethyl-19-norpregn-4-ene-3,20-dione, I6alpha, 185 Imaging, 245 Etomidate, 64 Immunoaffinity chromatography, 4 Europium, 330 Immunoassay, 330 Exemestane, 527 In vivo studies, 153 Extra-renal angiotensin, 566 Indole-3-carbinol, 215 Extra-renal renin, 566 Inhibitors, 414 Insulin, 621 Fatty acids, 357 Insulin release, 335 Fermentation, 320 Insulin resistance, 621 Fluorescence, 157 Ion transport, 573 Fluorine-18, 157 lonic fluxes, 335 Follicle-stimulating hormone, 379 Isoflavone, 301 Follicular fluid, 324 Isolated rat hepatocytes, 74 Formylestradiol, 16-, 234 Ketobromosteroids, A4-3-, 170 GC/MS, 495 Koenigs-Knorr reaction, 452 General Anesthesia, 112 Genetic variation, 275 L2 cell, 357 Genistein, 301 Lead tetraacetate oxidation, 52 GLC, 362 Leydig cells, 314 Glucocorticoid receptor, 357, 400 Ligand, 245 Glucocorticoids, 580 Liver metabolism, 59 Glucose tolerance, 621 LNCaP, 439 Glycoside synthesis, 518 Lung, 357 Glycyrrhetinic acid, 153 Luteolin, 268 Goldblatt’s model, 588 Luteolin/bioflavonoid, 268 638 Steroids, 1993, vol. 58, December Subject Index Luteolin-binding type II sites, 268 PM3 molecular orbital calculation, 423 Luteolin covalent ligand type II sites, 268 Point mutation, 275 Polymerase chain reaction, 275 Mammary carcinoma, 106 Polymyxin-E, 100 Marine algae, sterols in, 178 Polymyxin-B, 100 Marine sterols, 178, 508 Postmenopausal estrogen replacement, 196 Marine sponge, 410 Potassium, 305 Mass spectrometry, 387, 484 Potential metabolites, 527 Menopausal estrogen therapy and cancer risk, 196 Precursor, 379 Metabolites, 79, 484 Pregnane derivatives, 396 Methone, 141 Pregnanolone, 112 Methylenandrosta-1, 4-diene-3, 17-dione, 6-, 527 Pregnenolone, 230 Methyl-17a—(E-2’-['*Iiodovinyl)—19-nortestosterone, 7a—, 113 Pregnyne derivatives, 220 Methyl-a-bromomethylacrylate, 234 Preparation of, l6alpha-, 185 Microbial transformation, 79, 484 Proacame, 407 Microbial hydroxylation, 278 Progestagens, 196, 605 Mineralocorticoids, 580 Progestagens and cancer risk, 196 Mineralocorticoid activity, 59 Progesterone, 466, 478, 547 Mineralocorticoid hypertension, 611 Prolame, 407 Mineralocorticoid receptors, 611 Proliferation, 100 Modified Raney nickel catalyst, 533 Prostaglandin F,,, 100 Monoclonal antibodies, 4 Prostate cancer, 439 Mononuclear leukocytes, 611 Protein kinase-C, 100 MS, 351, 362 Protein kinase-c, estradiol and proliferation, 100 Mutant, 275 Pseudohypoaldosteronism, 611 Pycnosporium spec. ATCC 12231, 278 N-methylmorpholine N-oxide, 205 Na* retention, 24 Radiolabeled, 245 Na‘/H* exchange, 491 Radiolabeled estrogens, 245 Na’ transport, 580 Radioligand, 462 Neural graft, 594 Rat liver 118-hydroxysteroid dehydrogenase, 153 NMR, bromo-substituted steroids, 170 Receptor, 245 NMR, 2D, 170, 260, 320 Receptors, 478 NMR, 484, 495, 518 Red algae, 178 NMR spectroscopy, 370 Red blood cell, 540 Non-insulin-dependent diabetes, 621 Reductase/3a,38—hydroxysteroid dehydrogenase/178—dehydrogen- Non-isotopic labeling, 330 ase, Sa, 429 Noraldosterone and adrenal adenoma, 19, 282 Reductase, Sa—, 472 Norandrostenedione, |3a-h-18-, 141 Renal hypertension, 588 Norethisterone trifluoracetate, 220 Renin-angiotensin, 588 Norpregenes, 19-, 185 Renin-angiotensin system, 566 Norpregna-4, 16-diene-3,20-dione, 19-, 185 Renovascular lesions, 588 Norpregna-4, 16-diene-20-yn-3-one, 19-, 185 Resuscitation, 536 Norpregna-4, 16-dien-20-yn-3-one, 19-, 220 Retroaldolization, 141 Norprogesterone derivatives, 19-, 115 Reversed micelles, 547 Norsteroids, 18-, 141 Risk factors, 196 Role in blood pressure regulation, 566 Obesity, 621 Role in cardiovascular disease, 566 ORG 2058, 115 Rumen content of sheep, 387 Ovariectomy, 466 Oxidation, 205 Salt, 106 Oxidation of steroidal alcohols to ketones, 205 Salt appetite, 594 Oxygen-17('70), 260 Sea cucumber sterols, 508 Oxygenated androst—4—ene—3,6,17-trione, 19-, 423 Sea cucumber triterpenoids, 508 Oxygenated 4a—alkylthio-Sa—androstane-—3,6,17-trione, 19-, 423 Selective protection, 452 Ozonation, 225 Sex hormone binding globulin, 301 Ozonation products, 2,4-, 225, 230 Sex hormone, 286 Ozonation biomarker molecules, 225 Sex hormones and coronary heart disease, 286 Sexual differentiation, 126 Pentolame, 457 Shark testis, 87 Peptides, 35 Shark, 370 Peroxisomes, 351 Sodium, 305 Phosphatidylserine, 472 Soy, 301 Phosphatidylcholine, 472 Spacer, 330 Phospholipase A2, 491 Species difference, 540 Phospholipid methylation, 314 Spectra-structure correlations, 17 O-, 260 Phospholipids, 472, 491 Spent medium, 379 Photoaffinity labeling, 462 Spermatogenesis, 87 Pig, 466 Spermidine, 370 Pilosebaceous unit, 429 Spirostane, 58-, 387 Pinealocyte, 466 Sponge sterols, 134 Placenta mitochondria for enzymatic synthesis, 230 Spongia officinalis, 134 Placental mitochondria, 230 Spongiidae, 134 Platelet aggregation, 407 Spontaneously hypertensive rats, 594 Steroids, 1993, vol. 58, December 639 Subject Index SSF-109, 74 Therapy, 245 Stereomechanism, 423 Thin-layer chromatography, 429 Steroid anesthesia, 112 Time-dependent inactivation, 40 Steroid ketones, 260 FELG, 362 Steroid receptors, 13 Total assignment, 170 Steroidal alcohols, 205 Training, 348 Steroidogenesis, 87, 314 Transcortin, 275 Steroids, 4-en-3-one, 170 Transcortin genetic variation, 275 Steroids, 4, 13, 24, 35, 59, 64, 69, 87, 100, 106, 112, 115, 141, 148, Transcortin mutant/variant, 275 153, 157, 185, 215, 220, 230, 234, 245, 268, 275, 282, 286, 305, Transformation of norethisterone acetate, 115 314, 324, 330, 335, 348, 351, 357, 362, 379, 387, 400, 423, 429, Two-dimensional nuclear magnetic resonance, 170 439, 452, 457, 472, 478, 484, 494, 499, 527, 540 Type II (H]estradiol-binding sites, 268 Sterol, 225, 370, 410 Sterol esters, 260 Ultrastructure, 466 Sterols, 52, 74, 79, 119, 260, 462 Uterine cells, 209 Structure, 410 Uterine cells in culture, 209 Structure-activity relationships, 518 Uterus, 478 Substituted androsta—1,4—diene—3,17—diones, 7a—, 414 Substituted estrogen, 7a, 157 Vaginal cells, 209 Suicide substrate, 40 Vaginal cells in culture, 209 Sulfatase inhibitors, 106 Vascular smooth muscle, 580 Supersensitive, 439 Vasoactivity, 573 Synthesis, 181, 185, 220, 245, 452, 495, 524 Vitamin D, 491 Systems, 205 Vitamin D3 deficiency, 335 Testicular feminized male rats, 126 Wrestling, 348 Testosterone, 286, 301 Testosterone and coronary heart disease, 286 X-ray diffraction analysis, 134 Testosterone metabolism, 429 Tetrapropylammonium perruthenate, 205 (HJORG 2058, 115 t Statement of Ownership, Management and Circulation Required by 39 U S.C 3685, Eovtor (Thus wem MUST NOT be Blank) Montval e Avenoe, Stoneham, West Street, Antenucci Bldc., Montvale m| ec eratibfoyv et haatr e thceo rrsetcatt eamnedn tsc ommpaldeet e by PS Form 3526. Vice President and CF: 640 Steroids, 1993, vol. 58, December