Table Of Content

STATISTICS IN MEDICINE VOL. 16, 2941-2943 (1996) AUTHOR INDEX Aalen, O. O., 2191 Chuang-Stein, C., 2599 Fleming, T. R., 1515 ACSF Investigators, 397 Clark, I., 1745 Fuerst, T. P., 1889 Agresti, A., 2599 Clark, L. C., 853 Aickin, M., 1845 Cnaan, A., 2349 Gail, M., 133 Akazawa, K., 583 Commenges, D., 1283 Gamel, J. W., 1629 Andersen, P. K., 215 Connelly, R. R., 1401 Gao, S., 783, 2049, 2419 Anderson, S., 44i Cook, P., 321 Gatsonis, C., 2311 Ashby, D., 1413 Cook, R. J., 911 Gee, L., 441 Austin, H., 1005 Coste, J., 561 Gefeiler, O., 981, 1107 Couper, D., 1551 Genant, H. K., 1889 Bacchetti, P., 645 Crichton, N. J., 717 Gilks, W. R., 741 Bailey, N. T. J., 2447 Cui, J.-S., 2339 Gill, O. N., 2191 Barai, U.,.941 Cuzick, J., 1017 Gill, R., 39 Becher, H., 993 Glidden, D. V., 833 Becker, N. G., 2339 Dain, B., 1943 Glynn, R. J., 357 B,l isle, P., 769 Daniels, M. J., 1965, 2311 Goldberg, R., 1311 Benichou, J., 133 Dartiques, J., 1283 Goldbourt, U., 1873 Bennett, C. L., 1451 Davidian, M., 1765 Gonin, R., 1925 Bernardinelli, L., 741 Davis, C. E., 2009 Gordon-Salant, S., 2475 Best, N. G., 741 Day, N. E., 2191 Gore, S. M., 2459 Betensky, R. A., 465, 2429, De Angelis, D., 2191 Gray,J .C ., 1481 2587 De Angelis, R., 425 Greenland, S., 515 Biggerstaff, B. J., 753 De Gruttola, V., 1515 Greenwood, C. M. T., 545 Biscay, R., 1745 Dear, K. B. G., 2177 Grill, S. E., 2245 Bixler, E. O., 1995 Deville, J.-C., 397 Gu, C., 1357 Bjorling, L. E., 1175 Dey, D. K., 1817 Blood, J., 681 Diehr, P., 1211 Haber, M., 601 Bois, F. Y., 441 Dobson, A. J., 2177 Hadgu, A., 1391, 2403 Boyett, J. M., 2095 Donner, A., 1097, 1753 Hakulinen, T., 2297 Brant, L. J., 2475 Drescher, K., 117 Hall, W. J., 2143 Brenner, H., 981 Du Berger, R., 769 Halpern, J., 153 Breslow, N. E., 103 Dubey, S. D., 2529 Hamilton, S. A., 2029 Brettle, R. P., 2459 Dunnett, C. W., 2489 Hanrahan, J. P., 1603 Brittain, E., 681 Dunstan, F. J., 1481 Hardy, R. J., 2063 Broemeling, L. D., 321 Dyba, T., 2297 Hashemi, L., 1311 Brookmeyer, R., 1983 Hauck, W. W., 441, 545, Brown, B. W., 2511 Edwards, R., 1017 1683 Brown, E. B., 803 Eliasziw, M., 1097 Heijde, D. van der, 1653 Bull, K., 1041 Elswick, R. K., Jr., 1695 Heinze, G., 73 Bull, S. B., 545 Erkanli, A., 1121 Heitjan, D. F., 347, 1791 Byrne, C., 133 Etzioni, R., 627 Hinde, J. P., 717 Hodges, J. S., 1175 Cai, J., 2009 Fairclough, D. L., 1197 Hogan;J . W., 239, 259 Capocaccia, R., 425 Faraggi, D., 2573 Holubkov, R., 103 Carey, V. J., 1667 Farewell, V. T., 2191 Hosmer, D. W., 965 Carroll, R. J., 169 Fatti, L. P., 333 Hosmer, T., 965 Carter-Campbell, S., 695 Fay, M. P., 791, 2389 Hughes, M. D., 865, 1965 Catalano, P. J., 883 Fayers, P. M., 1413 Hui, S., 1889 Chen, L., 1167 Feuer, E. J., 791, 2389 Hui, S. L., 2419 Chen, R., 1401, 1873 Fick, G. H., 373, 2103 Huque, M. F., 2529 Chow, S.-C., 1031 Finkelstein, D. M., 951 Hyslop, T., 441 2942 AUTHOR INDEX Iscovich, J., 1873 Marchini, J., 717 Romano, P. S., 1301(L) Iyer, H. K., 803 Marshall, R., 2022(L) Romanowski, B., 2103 Martin, D. O., 1005 Rose, M. S., 373, 2103 Jacqmin-Gadda, H., 1283 Martinussen, T., 273 Rosenberger, W. F., 2245 Jereb, J. A., 485 Mathews, J. N. S., 705 Rosner, B., 357 Jiang, W., 853 Mathur, A. K., 1889 Rotnitzky, A., 81 Jim,nez, J. C., 1745 Matsuyama, Y., 1587 Russek-Cohen, E., 455 Johnson, W. D., 1081, 2127 Matts, J. P., 1943 Russell, K., 2511 Jones, B., 1955 May, W. L., 1081, 2127 Joseph, L., 769 Mehrotra, D. V., 1465 Sankoh, A. J., 2529 Meier, K. L., 1337 Schemper, M., 73 Kaiser, M. S., 1151 Meisner, M., 2211 Schill, W., 117 Keiding, N., 215, 273 Messiah, A., 397 Schmoor, C., 225 Klar, N., 1753 Meyer, L., 397 Schoenfeld, D. A., 951 Klein, B., 1357 Mian, I. U. H., 1497 Schumacher, M., 225 Klein, J. P., 215 Miller, C., 1943 Schwartz, P. F., 1695 Klein, R., 1357 Milner, P. C., 2117 Scott, A. J., 1377 Klerk, E. de, 1653 Morrell, C. H., 2475 Seaman, S. R., 2459 Knapp, R. G., 1705 Moy,, L. A., 2267 Segal, M. R., 1603 Koch, G., 2403 Segnan, N., 1017 Kiichenhoff, H., 169 Nakamura, T., 583 Senn, S., 1303(L), 2021(L) Kuha, J., 189 Nandram, B., 1311 Shao, J., 1031, 1167 Neely Atkinson, E., 1803 Shapiro, D. E., 2143 Lachin, J. M., 653 Nejjari, C., 1283 Sharma, D., 347 Lagakos, S. W., 925 Nelson, E. T., 1943 Shen, Y., 627 Laird, N. M., 239, 259, 2349 Neuh,,user, M., 993 Shih, W. J., 1225, 1913 Langer, S. F. J., 1617 Ng'andu, N. H., 611 Shoukri, M. M., 1497 Larose, D. T., 1817 Nix, A. B. J., 1481 Siev, D., 1151 Laska, E. M., 2211 Simon, R., 2573 Lau, T. S., 2283 Obuchowski, N. A., 1529 Simon, R. M., 455 Launer, C. A., 1943 Ohashi, Y., 1587 Slasor, P., 2349 Lawless, J. F., 911 Smith, P. J., 485 Lazaridis, E. N., 1925 Paivarinta, L., 2297 Soltysik, R. C., 1451 Le Cessie, S., 965 Palensky, J., 681 Soyer, R., 1121 Leblond, L., 203 Palesch, Y., 583 Spiegelhalter, D. J., 1041 Lee, A. J., 1377 Pan, G., 1645 Sposto, R., 695 Lee, S. Y., 1859 Park, T., 1859 Stablein, D., 695 Lee, W.-C., 729 Parmar, M. B., 1413 Stamenovic, E., 951 Leisenring, W., 1263 Pascutto, C., 741 Stangl, D., 1121 Lele, C., 2543 Patrick, D. L., 1211 Strémberg, U., 2327 Lellouch, J., 397 Pearson, J. D., 2475 Sun, J., 497 Lemeshow, S., 965 Pepe, M., 5 Li, Q. H., 925 Pepe, M. S., 1263, 1551 Tager, I. B., 1603 Li, Y., 2095 Perkins, L. L., 1005 Tamhane, A. C., 2489 Lin, D. Y., 901, 1515 Pichlmeier, U., 1107 Tang, D.-I., 2211 Linden, S. van der, 1653 Pitard, A., 527 Tango, T., 2621(L) Lindsey, J. K., 1955 Psaty, B. M., 1211 Ten Have, T. R., 1995 Liu, Q., 711(L), 2095 Puterman, M. L., 2177 Teoh, N., 941 Longton, G., 1263 Pyke, S. D. M., 2063 Terry Beirn Community Love, E. J., 2103 Programs for Clinical Lu, Y., 1889 Quan, H., 1225 Research on AIDS, 1943 Lui, K.-J., 1777 Therneau, T. M., 2029 Reilly, M., 5 Thompson, M. L., 333 McClish, D. K., 1529 Reynolds, T., 1481 Thompson, S. G., 2063 McKee, L. J., 1683 Richardson, S., 203 Thompson, T. J., 485 Mackenzie, G., 1831 Ritov, Y., 285 Tibshirani, R., 385 McMurchy, L., 1377 Robins, J., 81 Tierney, C., 2587 McNeil, A. J., 2555 Robins, J. M., 21, 39, 285 Torrance-Rynard, V. L., 2157 McShane, L. M., 1337 Roe, D. J., 1241 Tretli, S., 1435 Mantel, N., 1401 Rogerson, P. A., 2081 Turnbull, B. W., 853 AUTHOR INDEX Turner, B. J., 1683 Walker, S., 1135 Wittes, J., 681 Tweedie, R. L., 753 Wallenstein, S., 1329 Wolfe, D. A., 1645 Walsh, S. J., 669 Xie, T., 1845 Umbach, D. M., 1731 Walter, E., 561 Xue, X., 1983 Urquhart, J., 1653 Walter, S. D., 2157 Wang, C. M., 803 Yarnold, P. R., 1451 Vacek, P. M., 505 Wang, Y., 1357 Ye, K., 1889 Vach, W., 57 Warszawski, J., 397 Varga, P., 821(L) Wasserman, D., 561 Venot, A., 561 Wassermann, E. M., 1337 Zackin, R., 571 Viel, J. F., 527 Wei, L. J., 571, 833 Zahl, P.-H., 1435, 1573 Vogel, R. L., 1629 Weinberg, C. R., 1731 Zeng, Q., 1765 Voit, E. O., 1705 Welsh, J. A., 1695 Zhao, P.-L., 1913 Vuorinen, J., 2229 Westrom, L., 2403 Zhou, H., 1301(L), 2009 White, I. R., 2619(L) Zhou, X., 783 Wahba, G., 1357 Whittemore, A. S., 153, 2543 Zhou, X.-H., 2049 Wakefield, J., 1135 Wight, S., 1603 Zou, K. H., 2143 STATISTICS IN MEDICINE, VOL. 16, 2945-2962 (1997) SUBJECT INDEX“ Notes: Single page numbers refer to individual papers. The page ranges shown indicate collections of papers on particular subjects. (L) after some page numbers identifies letters. Accident and emergency Almon’s method, 527 forecasting models, 2117 Analysis of variance longitudinal study, 2928 F tests, 2729 Accrual buffers, 1925 intraclass correlations, 1497 Accuracy smoothing spline methods, 1357 clinical trials, 705 Anderson-Gill model, 2029 indices ROC curves, 1529 Anginal attacks, 1955 Adenomatous polyps, 1845 Antigens, 1151 Adjustment non-parallel immunoassay curves, 1151 multiple endpoints, 2529 Antiretroviral therapy Age rule-based ranking schemes, 1175 breast cancer, 133, 1435 ARIMA see Autoregressive integrated moving data-dependent interval partition, 1617 averages Age-specific rates Artherosclerosis see Coronary artery disease reference intervals, 2785 Assays AIDS (Acquired immunodeficiency syndrome) cell dilution, 571 see also CD4 lymphocyte counts; HIV Association asymptotic period, 627 continuously monitored strategy, 1925 clinical trials Asthma endpoint, 951, 1175 treatment divergence, 2855 surrogate markers, 1515, 1965 Asymptotic confidence intervals, 1329 cumulative incidence function, 901 Asymptotic relative efficiency, 117 delay data, 2339 Attributable risk follow-up losses, 1943 Bayesian inference, 1311 incidence, 645 epidemiology, 729 longitudinal studies, smooth curves, 2429 recurrent disease events, 1107 Markov model analysis, 2191 risk factor prevalence, 2543 pneumonia, 1451 Autoregressive integrated moving average models Air pollution, 2928 accident and emergency attendances, 2117 Alcoholism reparametrization, 1745 diagnosis test, 1695 Algorithms Backcalculation see also Expectation maximization algorithm; HIV diagnosis, 2191 Markov Chain Monte Carlo algorithm Baseline measurements CODA, 285 biased baseline rates, 1401 LABROC4, 2143 heterogeneity, 2883 Metropolis-Hasting algorithm, 1817 Bayesian inference ROC & ROL, 2143 autocorrelated errors, 321 Allocation ratio sample size calculation, 2805 binomial proportions, 1311 * Compiled by INDEXING SPECIALISTS, 202 Church Road, Hove, East Sussex, BN3 2DJ, U.K. 2946 SUBJECT INDEX Bayesian inference (cont.) Bladder cancer, 865 CODA asymptotic theory, 285 Blinded subjective ranking dose determination, 1135 treatment effect, 681 hierarchical models Blood pressure disease maps, 741 intraclass correlations, 1497 variability analysis, 2311 missing data, 2713 immunological progression rates, 2555 BMDP computer package independence models, chest pain diagnosis, 717 mixed models, 2349 measurement errors, 203 Bone marrow meta-analysis, 1817 transplants persuasion probability, 1791 busulfan concentrations, 2095 proportional hazards model, 2573 continuous monitoring, 1925 sample sizes, 769 graft-versus-host disease, 1551 treatment evaluation, 1803 Bone mineral density, 1889 two-phase prevalence studies, 1121 Book reviews underlying risk, 2741 Agresti, A., An Introduction to Categorical Data Bayesian monitoring scheme Analysis, 2383 interim analysis, 1413 Arminger, G., Clogg, C. C. and Sobel, M. E., Bayes’ theorem, 1413 Handbook of Statistical Modeling for the Beta-binomial model, 2849 Social and Behavioural Sciences, 1433 Bias Armitage, P. and David, H. A., Advances in baseline rates, 1401 Biometry, 2137 cutpoint model, 2813 Baker, F. B., Item Response Theory. Parameter diagnostic tests, 1391 Estimation Techniques, 2261 measurement error, 169 Bell, F. D., Basic Statistics: Concepts for the model misspecification, 669 Health Sciences: The Almost No Math Stats observational studies, 1041 Book, 1307 reduction, 545 Beolchi, L. and Kuhn, M. H., Medical Imaging- Binary response Analysis of Multimodality 2D/3D Image, correlated data, 1081, 2127 2630 double-blind clinical trials, 1913 Berry, D. A. and Stangl, D. K., Bayesian mixed effects models, 1587 Biostatistics, 1655 randomized clinical trials, 1017 Bishop, C. M., Neural Networks for Pattern recurrent disease events, 1107 Recognition, 2385 teratologic studies, 2843 Blond, M., An Introduction to Medical Statistics, two-stage data, 103 2262 Binary screening tests, 2282 Bowers, D., Statistics from Scratch: An Binormal model ROC analysis, 669 Introduction for Health Care Professionals, Bioassays 2932 non parallel dose-response curves, 1151 Breen, R., Regression Models: Censored, Bioavailability Sample-Selected, or Truncated Data, bioequivalence, 803, 2229 1789 replicate crossover designs, 1031 Buncher, C. R. and Tsay, J. Y., Statistics in the Biochemical markers, 1481 Pharmaceutical Industry (2nd edn), 1909 Bioequivalence Busby, C., Wings of Death: Nuclear Pollution higher-order cross-over designs, 1031, 2229 and Human Health, 2025 individual, 803 Campbell, M. J. and Swinscow, T. D. V., population, 441 Statistics at Square One, 2629 Biographies Carroll, R. J., Ruppert, D. and Stefanski, L. A.., Semmelweis, I. P., 2767 Measurement Error in Nonlinear Models, Biostatistics 2628 future trends, 2773 Chalmers, I. and Altman, D. G., Systematic Birthweight Review, 2929 logistic regression model, 965 Chatfield, C., The Analysis of Time Series - An maternal smoking, 1603 Introduction, 2386 Bivariate data Cleveland, W. S., The Elemants of Graphing discriminant analysis, 2679 Data, 481 power approximation, 865 Clogg, C. C. and Shihadeh, E. S., Statistical SUBJECT INDEX 2947 Models for Ordinal Variables. Advanced Kleinbaum, D. G., Survival Analysis: A Self- Quantitative Techniques in the Social Learning Text, 2934 Sciences 4483 Knapp, T. R., Learning Statistics Through Coggon, D., Statistics in Clinical Practice, 1193 Playing Cards, 1543 Cooper, H. and Hedges, L. V., The Handbook of Kreienbrock, L. and Schach, S., Research Synthesis, 713 Epidemiologische Methoden, 829 Corter, J. E., Tree Models of Similarity and Krzanowski, W. J., Recent Advances in Association, 1546 Descriptive Multivariate Analysis, 1787 Di Rienzo, M., Mancia, G., Parati, G., Pedotti, Lange, N., Ryan, L., Billard, L., Brillinger, D., A. and Zanchetti, A., Computer Analysis of Conquest, L. and Greenhouse, J., Case Cardiovascular Signals, 1195 Studies in Biometry, 963 Eerola, M., Probabilistic Causality in Lehtonen, R. and Pahkinen, E. J., Practical Longitudinal Studies, 2761 Methods for Design and Analysis of Esteve, J., Benhamou, E. and Raymond, L., Complex Surveys, 482 Statistical Methods in Cancer Research. McNeil, D., Epidemiological Research Methods, Vol IV. Descriptive Epidemiology, 715 2381 Everitt, B. S., The Cambridge Dictionary of Manton, K.G., Woodbury, M. A. and Tolley, Statistics in the Medical Sciences, 1910 H.D., Statistical Applications Using Fuzzy Feinstein, A. R., Multivariate Analysis: An Sets, 1789 Introduction, 2382 Marubini, E. and Valsecchi, M. G., Analysing Finkel, S. E., Causal Analysis with Panel Data, Survival Data from Clinical Trials and 1547 Observational Studies, 2138 Fischer, G. H. and Molenaar, I. W., Rasch Matthews, J. R., Quantification and the Quest for Models. Foundations, Recent Developments Medical Certainty, 1908 and Applications, 1431 Meinert, C. L., Clinical Trials Dictionary: Forthofer, R. N. and Lee, E. S., Introduction to Terminology and Usage Recommendations, Biostatistics. A Guide to Design, Analysis, 1911 and Discovery, 1075 Mollison, D. (ed), Epidemic Models: Their Gabler, E., Biometrische Methodik Structure and Relation to Data, 1666 Pharmakologischer Tierexperimente, 2139 Moore, T. J., Deadly Medicine: Why Tens of Glasbey, C. A. and Horgan, G. W., Image Thousands of Patients Died in America’s Analysis for the Biclogical Sciences, 2759 Worst Drug Disaster, 2507 Goldstein, H., Multilevel Statistical Models (2nd O’Hagan, A., Kendall’s Advanced Theory of edn), 1309 Statistics. Volume 2B, 1907 Grayson, Lesley, Scientific Deception: An Paling, J., Up To Your Armpits in Alligators? Overview and Guide to the literature How To Sort Out What Risks Are Worth of Misconduct and Fraud in Scientific Worrying About!, 2929 Research, 599 Parmar, M. B. K. and Machin, D., Survival Greenwood, P. E. and Nikulin, M. S., A Guide to Analysis: A Practical Approach, 714 Chi-squared Testing, 2263 Peto, R., Lopez, A. D., Boreham, J., Thun, M. Haccou, P. and Meelis, E., Statistical Analysis of and Heath, C. Jr., Mortality from Smoking Behavioural Data - An Approach Based on in Developed Countries, 1544 Time-structured Models, 1079 Rasch, D., Tiku, M. L. and Sumpf, D., Elsevier’s Hampton, R. E., Introductory Biological Dictionary of Biometry, 1080 Statistics, 1308 Rees, D. G., Essential Statistics for Medical Hand, D. and Crowder, M., Practical Practice - A Case-Study Approach, 1194 Longitudinal Data Analysis, 2026 Selvin, Steve, Practical Biostatistical Methods, Hayduk, L. A., LISREL - Issues, Debates, and 600 Strategies, 1911 Sloan, M. D., Using Designed Experiments to Hill, C., Com-Nougué, C., Kramar, A., Moreau, Shrink Health Care Costs, 2627 T., O’Quigley, J., Senoussi, R. and Stapleton, J. H., Linear Statistical Models, 1076 Chastang, C., Analyse Statistique des Strike, P., MEDSAP. A Statistical Toolkit for Données de Survie, 1550 Health Professionals Version 22265 Hoch, J. C. and Stern, A. S., NMR Data Thall, P., Recent Advances in Clinical Trial Processing, 2935 Design and Analysis, 1077 Isham, V. and Medley, G., Models for Infectious Utts, J. M., Seeing Through Statistics, 2931 Human Diseases: Their Structure and Venables, W. N. and Ripley, B. D., Modern Relation to Data, 1545 Applied Statistics with S-PLUS, 1548 2948 SUBJECT INDEX Book reviews (cont.) Carryover effects Verma, B. L., Shukla, G. D. and Srivastava, R. replicate crossover designs, 1031 N., Biostatistics: Perspectives in Health CART see Classification and regression tree. . . Care Research and Practice, 825 Case-control studies Viertl, R., Statistical Methods for Non-Precise colorectal cancer, 1845 Data, 1194 data re-using, 1377 Wallgren, A., Wallgren, B., Persson, R., Jorner, early stopping, 2327 U. and Haaland, J-A., Graphing Statistics genotype/exposure independence, 1731 and Data, 2760 meta-analysis, 1005 Weir, B. S., Human Identification: The Use of post-hoc stratification, 993 DNA Markers, 828 relative attributable risk, 2543 Bootstrap two-stage methods, 103, 117, 133 directly standardized rates, 791 Categorical data log-normal means, 783 latent variable model, 883 resampling technique, 2813 CD4 lymphocyte counts Breast cancer see also AIDS; HIV asymptomatic period, 627 HIV, marker, 1965 chemotherapy trials, 1629 pre-AIDS mortality, 2459 DNA flow cytometry, 2813 progression rates, 2555 exposure-specific rates, 133 Centile estimates long-term survival, 1435 multivariate approach, 333 prognostic markers, 2573 Change-score analysis, 1211 quality of life analysis, 1197 Chemotherapy radiation effect, 21, 39 chemoimmunotherapy trial, 11803 Breast implants, 1005 survival analysis, 1629 British Family Heart study, 2063 Chest conditions Bronchitis pain diagnosis, 717 dust concentration, 169 Chlamydia trachomatis, 1391 BUGS computer package, 2741 Cholesterol Burkitt’s lymphoma, 2081 repeated measurements analysis, 653 Chronic diseases CABG see Coronary artery bypass grafting non-fatal recurrent events, 1831 Calcium level, 1587 recurrent/terminating events, 911, 925 Calibration Classification comparative study, 1889 method comparison studies, 705 immunoassay curves, 1765 optimal discriminant analysis, 561, 1451 CAN see Consistent and asymptotically normal. . . Classification and regression tree (CART) Cancer technique, 717 see also Breast cancer Classification tree analysis (CTA), 1451 asymptomatic period, 627 Clinical trials Bayesian interim analyses, 1791 see also Randomization; Stopping rules case-control studies, 993 AIDS, failure time, 951 data monitoring, 1413 Bayesian analysis, monitoring, 1413 incidence prediction, 2297 binary response studies, 1913 mortality, occupational, 505, 515 contamination, 1017 phase III clinical trials, 1845 continuous monitoring strategy, 1925 prevalence, 425 data monitoring, 1413 quality of life assessment, 1197 drop-outs, treatment comparison, 1225 survival analysis, excess hazards, 1573 endpoints study, 1175, 1197, 2267 three-stage designs, 2701 follow-up losses, #943 Canonical systems, 1705 health status, 1197, 1211 Cardiac data processing, 1617 heterogeneity, 583, 2009 Cardiology HIV, recurrent/terminating events, 925 variability analysis, 2311 incomplete covariate data workshop, 1-319 Cardiovascular diseases interval-censored data, 497 clinical trials, 2267 losses to follow-up, 1943 risk, frailty model, 1983 multiple endpoints, 2529 risk factors, 1983 multiple events data, 833-951 SUBJECT INDEX multivariate time-to-event data, 865 Computers phase II correlated data analysis, 2349 Bayesian interim analysis, 1791 observational studies, 1667 three-stage design, 2701 Conditional models stopping rules, 465, 1925 ectopic pregnancy, 2403 treatment efficacy, 1017 measurement errors, 203 treatment interaction, 1645 Conditional power calculations, 465 Cluster analysis Confidence intervals bivariate model, 883 binomial proportions, 1329 leukaemia, 1873 correlated proportions, 2127 naturally ordered individuals, 1617 directly standardized rates, 791 teratologic studies, 2843 first event ocurrence, 711-712(L) Cluster randomization log-normal means, 783 community interaction trials, 1753 longitudinal studies, 2429 mean hazard ratio parameters, 2009 qualitative interaction test, 1645 ‘ meta-analysis, 2063 quality performance index, 1301—1303(L) CODA see Curse of dimensionality. . . treatment evaluation, 1017 Cohort studies vital rates, 2389 two-stage sampling, 133 Confounders Collinearity logistic regression model, 993 pollutants/climatic conditions, 527 Confounding Colorectal cancer attributable risk, 1107 adenomatous polyps ocurrence, 1845 Connective tissue disease, 1005 Combination Consistent and asymptotically normal estimators across study designs, 1005 (CAN), 81 treatments, 2211 Contamination Community interventions fish, 2327 pair-matched design, 1753 soils, 1167 Community Programs for Clinical Research on Continence status, 1859 AIDS, 1175 Contingency tables Comparative calibration model, 1889 dose-response studies, 2599 Comparative studies Continuation ratio model binomial probabilities, 1329 ordinal responses, 2873 discordant classification, 705 Continuity correction dropouts, 1225 confidence intervals, 1329 goodness-of-fit tests, 965 exact equivalence tests, 1777 proportional hazards assesment, 611 Yates’, 1329 quality of life trials, 1197 Continuous confounders case-control studies, 993 sets/cuscore techniques, 1401 Continuous data spatial prediction techniques, 1337 multivariate analysis, 883 treatment effects, 1645 sample size, 2805 variance components estimators, 1465 Continuous exposures, 729 Competing risks Continuous monitoring, 1925 cumulative incidence functions, 901 Coronary artery bypass grafting (CABG), 2645, mortality, multivariate data, 951 2829 Complete cases Coronary artery disease estimates, 57 statistical models, 2829 Complex survey data, 2419 Corrections Compliance multiple testing, 2511, 2529 drug dosing histories, 1653 Corrections to published papers, 479, 480, 1299- randomized clinical trials, 1017 1300, 2927-8 Computer packages Correlated frailty model, 1573 see also SAS... Correlations goodness-of-fit, 965 binomial proportions, 1081, 1587, 2127 MEMS, 1653 generalized linear mixed model, 2349 multivariate failure time data, 2049 geographical distribution, 1283 NONMEM, 1135, 1241 intraclass coefficient, 821-823(L) SPSS-PC, 1041 measurement errors, 2177 2950 SUBJECT INDEX Cortical maps, 1337 interval censoring, 485, 497 Counting process longitudinal, 239, 259, 273, 2429 recurrent event analysis, 2029 net-work based mapping, 1667 Covariates skewness, 2785 incomplete data survival analysis, 1629 drop-outs, 239, 259, 273 validation, 189, 203 hot-deck multiple imputation, 5 Data monitoring committees (DMCs) measurement errors, 169, 189, 203, 741, 853 interim analyses, 1413 multi-stage studies, 153 Data re-using, 1377 non-response models, 21, 39, 81 Decision thesholds, 669 prognostic factors, 57, 73, 225 Delay distribution, 2339 two-stage studies, 103, 117 Dementia studies, 2419 logistic regression, 1695 Depression missing values, complex survey data, 2419 prevalence in adolescents, 1121 multivariate failure time data, 2049 Designs Coverage probability see also Two-stage design continuity correction, 1329 paired cluster randomization, 2063 mean confidence intervals, 783 phase II trials, 2701 Cox proportional hazards model tolerance intervals, 803 see also Non-proportional hazards model Detection rates screening, 1481 canonical system derivation, 1705 Developmental toxicity studies, 883 confidence intervals, 783 Diabetes heterogeneity, 583 cortical cataract, 357 incomplete covariate data, 21, 73, 225 disease mapping, 741 multiple event data, 951 retinopathy, risk factors, 1357 multivariate failure time, 833 Diagnosis multivariate time-to-event data, 865 AIDS, Markov model, 2191 proportional hazards assumption, 611, 1831 alcoholism, 1695 surrogate marker, 1515 CART methodology, 717 variable selection, 385 clustering, 1873 CPCRA see Community Programs for Clinical tests Research on AIDS accuracy, 1529 Cross-validation bias effect, 1391 cutpoint model, 2813 dependent errors, 2157 Crossover trials disease, prevalence estimation, 981 bioequivalence study, 803 marginal regression model, 1263 higher-order designs, 2229 model misspecification, 669 phase III, 2021-2022(L) ROC curves, 2143 treatment comparisons, 1031 Diet treatment-patient interactions, 1955 risk factors reduction, 2127 CTA see Classification tree analysis Directly standardized rates, 791 Cumulative incidence Discrepant analysis, 1391 AIDS, 2459 Discrete time survival data, 1983 competing risks, 901 Discriminant analysis Cumulative meta-analyses, 2901 classification tree analysis, 1451 Cumulative sum method ordinal responses, 561 surveillance, spatial patterns, 2081 sum of binary variables, 2679 Curse of dimensionality appropiate (CODA) Diseases asymptotic theory, 285 mapping, 741, 2773 Cuscore technique DNA biased baseline rates, 1401 amplification tests, 1391 Cytomegalovirus disease, 1263 U.S. blacks genes, 153 Dose Data augmentation, 189, 653 data analysis, 1653 Data collection Dose-response clustering, 357 initial dose selection, 1135 failure time, 215, 259, 497, 833, 841 non-parallel immunoassay curves, 1151 follow-up data, 2773 ordinal responses, 2599