Somatomedins and Some Other Growth Factors: Proceedings of the Twenty-Eighth Nobel Symposium held at Hässelby, Sweden, September 4–7, 1974 PDF
Preview Somatomedins and Some Other Growth Factors: Proceedings of the Twenty-Eighth Nobel Symposium held at Hässelby, Sweden, September 4–7, 1974
ADVANCES IN Metabolic Disorders Edited by Rachmiel Levine Rolf Luft City of Hope Medical Center Department of Endocrinology Duarte, California and Metabolism Karolinska Hospital Stockholm, Sweden Supplementary Volumes 1. Early Diabetes Edited by Rafael A. Camerini-Davalos and Harold S. Cole 2. Vascular and Neurological Changes in Early Diabetes Edited by Rafael A. Camerini-Davalos and Harold S. Cole ADVANCES IN Metabolic Disorders VOLUME 8 SOMATOMEDINS and Some Other Growth Factors Proceedings of the Twenty-Eighth Nobel Symposium held at Hässelby, Sweden, September 4-7, 1974 Edited by Rolf Luft Kerstin Hall Deportment of Endocrinology Department of Endocrinology and Metabolism and Metabolism Karolinska Hospital Karolinska Hospital Stockholm, Sweden Stockholm, Sweden Administrative Editor Vera Runnström-Reio 1975 @ ACADEMIC PRESS NEW YORK · SAN FRANCISCO · LONDON A Subsidiary of Harcourt Brace Jovanovich, Publishers COPYRIGHT © 1975, BY ACADEMIC PRESS, INC. ALL RIGHTS RESERVED. NO PART OF THIS PUBLICATION MAY BE REPRODUCED OR TRANSMITTED IN ANY FORM OR BY ANY MEANS, ELECTRONIC OR MECHANICAL, INCLUDING PHOTOCOPY, RECORDING, OR ANY INFORMATION STORAGE AND RETRIEVAL SYSTEM, WITHOUT PERMISSION IN WRITING FROM THE PUBLISHER. ACADEMIC PRESS, INC. Ill Fifth Avenue, New York, New York 10003 United Kingdom Edition published by ACADEMIC PRESS, INC. (LONDON) LTD. 24/28 Oval Road, London NW1 LIBRARY OF CONGRESS CATALOG CARD NUMBER: 64-14568 ISBN 0-12-027308-X PRINTED IN THE UNITED STATES OF AMERICA Contributors Numbers in parentheses indicate the pages on which the authors' contributions begin. J. B. BASEMAN Department of Bacteriology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina (127) K. BENIRSCHKE Department of Obstetrics and Gynecology, University of California, San Diego, California (301) RALPH A. BRADSHAW Department of Biological Chemistry, Division of Biology and Biomedical Sciences, Washington University, St. Louis, Missouri (285) GRAHAM CARPENTER Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee (265) D. R. CLEMMONS Department of Pediatrics, University of North Carolina, School of Medicine, Chapel Hill, North Carolina (127) STANLEY COHEN Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee (265) WILLIAM H. DAUGHADAY Metabolism Division, Department of Medicine, Washing- ton University School of Medicine, St. Louis, Missouri (151, 159) E. EIGENMANN Metabolic Unit, Department of Medicine, University of Zurich, Zurich, Switzerhnd (237) WERNER FRANK Max-Planck-Institut für Virusforschung, Abteilung für Physika- lische Biologie, Tübingen, West Germany (337) WILLIAM A. FRAZIER Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla, California (285) E. R. FROESCH Metabolic Unit, Department of Medicine, University of Zürich, Kantonsspital, Zürich, Switzerland (203, 211, 237) LINDA FRYKLUND AB KABI, The Recip Polypeptide Laboratory, Stockholm, Sweden (19, 47, 61) xv xvi Contributors LYNN P. GIMPEL Department of Physiology, Emory University, Atlanta, Georgia (H9) ALLAN L. GOLDSTEIN Division of Biochemistry, Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston, Texas (359) DENIS GOSPODAROWICZ The Salk Institute for Biological Studies, San Diego, Cali- fornia (301) JOHANNA GRIMM Max-Planck-Institut für Virusforschung, Abteilung für Physika- lische Biologie, Tübingen, West Germany (337) KERSTIN HALL Department of Endocrinology and Metabolism, Karolinska Hos- pital, Stockholm, Sweden (19, 47, 61, 73) R. HEIMANN Departments of Medicine and Biochemistry, University of Zürich, Zürich, Switzerland (203, 237) U. HEINRICH Department of Pediatrics, Erasmus University, Rotterdam, The Netherlands (171) A. C. HERINGTON* Metabolism Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri (151) R. L. HINTZ Department of Pediatrics, University of Connecticut, School of Medi- cine, Farmington, Connecticut (127) RAINER HOFFMAN Max-Planck-Institut für Virusforschung, Abteilung für Physika- lische Biologie, Tübingen, West Germany (337) RUTH A. HOGUE-ANGELETTI The Institute for Cancer Research, Philadelphia, Penn- sylvania (285) R. E. HUMBEL Departmeids of Medicine and Biochemistry, University of Zürich, Zürich, Switzerland (203) OLLE ISAKSSON Department of Physiology, University of Göteborg, Göteborg, Sweden (249) U. KAUFMANN Metabolic Unit, Department of Medicine, University of Zürich, Zürich, Switzerland (211) JACK L. KOSTYO Department of Physiology, Emory University, Atlanta, Georgia (249) * Present address: Medical Research Centre, Prince Henry's Hospital, St. Kilda Road, Melbourne, Australia. Contributors xvii KENNETH J. LEMBACH Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee {265) JON LINDSTROM The Salk Institute for Biological Studies, San Diego, California (301) ROLF LUFT Department of Endocrinology, Karolinska Hospital, Stockholm, Sweden (3, 73, 431) M. MÄDER Metabolic Unit, Department of Medicine, University of Zürich, Zürich, Switzerland (211) R. N. MARSHALL* Department of Pediatrics, University of North Carolina, School of Medicine, Chapel Hill, North Carolina (127) C. MEULI Metabolic Unit, Department of Medicine, University of Zürich, Zürich, Switzerland (211) Β. MORELL Metabolic Unit, Department of Medicine, University of Zürich, Zürich, Switzerland (211) IRA PASTAN Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (7, 377) L. S. PfflLLiPsf Metabolism Division, Department of Medicine, Washington Uni- versity School of Medicine, St. Louis, Missouri (151) HANS-JÜRGEN RISTOW Max-Planck-Institut für Virusforschung, Abteilung für Physi- kalische Biologie, Tübingen, West Germany (337) W. J. RITSCHARD Diagnostic Research Department, F. Hoffmann-La Roche ά Co., Basel, Switzerland (203) PHILLIP RUDLAND Imperial Cancer Research Fund, London, England (301) WILLIAM D. SALMON, JR. Veterans Administration Hospital and Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee (1S3) U. SCHLUMPF Departments of Medicine and Biochemistry, University of Zürich, Zürich, Switzerland (203, 237) * Present address : Department of Pediatrics, University of Texas Medical School, Houston, Texas. t Present address: Center for Endocrinology, Metabolism, and Nutrition, North- western University School of Medicine, Chicago, Illinois. xviii Contributors HANS SIEVERTSSON AB KAB1, The Recip Polypeptide Laboratory, Stockholm, Sweden (19, 47, 61) KAZUE TAKANO Department oj Endocrinology and Metabolism, Karolinska Hos- pital, Stockholm, Sweden (19, 61) L. E. UNDERWOOD Department of Pediatrics, University of North Carolina, School of Medicine, Chapel Hill, North Carolina (127) KNUT UTHNE AB KABI, The Recip Polypeptide Laboratory, Stockholm, Sweden (47, 101, 115) SYLVIA VAN BUUL Department of Pediatrics, Erasmus University, Rotterdam, The Netherlands (171) J. L. VAN DEN BRANDE Department of Pediatrics, Erasmus University, Rotterdam, The Netherlands (171) F. VAN ROON The Bergweg Hospital, Rotterdam, The Netherlands (171) A. C. VAN STEIRTEGEM The Free University of Brussels, Brussels, Belgium and The Medical Mission of CEMUBAC to IRSAC, Kuvu, Zaire (171) J. J. VAN WYK Department of Pediatrics, University of North Carolina, School of Medicine, Chapel Hill, North Carolina (127) JOSEF VESER Max-Planck-Institut für Virusforschung, Abteiling für Physikalische Biologie, Tübingen, West Germany (337) M. WALDVOGEL Metabolie Unit, Department of Medicine, University of Zürich, Zürich, Switzerland (211) ÂKE WASTESON Institute of Medical and Physiological Chemistry, Uppsala Univer- sity, Uppsala, Sweden (85, 101) BENGT WESTERMARK The Wallenberg Laboratory, Uppsala University, Uppsala, Sweden (47, 85, 101) ABRAHAM WHITE Syntex Research, Palo Alto, California and Department of Bio- chemistry, Stanford University School of Medicine, Stanford, California (359) ROSALYN S. YALOW Solomon A. Berson Research Laboratory, Veterans Administra- tion Hospital, Bronx, New York, and Department of Medicine, Mt. Sinai School of Medicine, The City University of New York, New York (73) J. ZAPF Departments of Medicine and Biochemistry, University of Zürich, Zürich, Switzerland (203, 211, 237) T. ZÜRCHER Department of Pediatrics, Erasmus University, Rotterdam, The Neth- erlands (171) Contents of Previous Volumes Volume 1 GLYCOGEN STORAGE DISEASE H. G. Hers THE PARATHYROIDS G. D. Arnbach and John T. Potts, Jr. MITOCHONDRIAL RESPIRATORY CONTROLS: BIOCHEMICAL, PHYSIOLOGICAL, AND PATHOLOGICAL ASPECTS Lars Ernster and Rolf Luft OSTEOPOROSIS B. E. C. Nordin BASAL METABOLIC RATE AND THYROID HORMONES J. R. Tata INSULIN ANTAGONISTS AND INHIBITORS J. Vallance-Owen ALDOSTERONE: ITS BIOCHEMISTRY AND PHYSIOLOGY John H. Laragh and William G. Kelley FOLIC ACID DEFICIENCY IN MAN AND ITS INTERRELATIONSHIP WITH VITAMIN B METABOLISM 12 A. Leonard Luhby and Jack M. Cooperman AUTHOR INDEX—SUBJECT INDEX Volume 2 GOUT James B. Wyngaarden NITROGEN-RETAINING STEROIDS AND THEIR APPLICATION IN DISEASE A. Querido and A. A. H. Kassenaar MACROGLOBULINEMIA Jan Waldenstrom xix XX Contents of Previous Volumes TESTING THE FUNCTIONAL CAPACITY OF THE TRYPTOPHAN-NIACIN PATHWAY IN MAN BY ANALYSIS OF URINARY METABOLITES J. M. Price, R. R. Brown, and Norma Y ess THE SYNDROME OF TESTICULAR FEMINIZATION A. Louis Southren AUTHOR INDEX—SUBJECT INDEX Volume 3 KETOGENESIS AND ITS REGULATION 0. Wieland SPONTANEOUS DIABETES AND/OR OBESITY IN LABORATORY RODENTS Albert E. Renold ETHANOL-INDUCED HYPOGLYCEMIA Leonard L. Madison HORMONAL SYNDROMES ASSOCIATED WITH NEOPLASIA Mortimer B. Lipsett METABOLIC DISORDERS OF THE OVARY Bruno Lunenfeld, Aliza Eshkol, Vaclav Insler, and Zaki Kraiem THE NATURE AND SIGNIFICANCE OF THE LONG-ACTING THYROID STIMULATOR Joseph P. Kriss THYROID AUTOANTIBODIES IN THYROID DISEASES Noel R. Rose and Ernest Witebsky ERYTHROPOIETIN Clifford W. Gurney AUTHOR INDEX—SUBJECT INDEX Volume 4 INTESTINAL FACTORS IN THE REGULATION OF INSULIN SECRETION Vincent Marks and Ellis Samols ANTIDIURETIC HORMONE SYNTHESIS, RELEASE, AND ACTION UNDER NORMAL AND PATHOLOGICAL CIRCUMSTANCES Niels A. Thorn Contents of Previous Volumes xxi DlSACCHARIDASE DEFICIENCY David H. Alpers and Kurt J. Isselbacher HORMONAL CONTROL OF FETAL DEVELOPMENT AND METABOLISM Alfred Jost and Luc Picon THE METABOLISM OF THE PLACENTA Andrew J. Szabo and Richard D. Grimaldi METABOLIC ASPECTS OF OBESITY E. S. Gordon THE USE OF LIQUID FORMULA DIETS IN METABOLIC STUDIES: 15 YEARS' EXPERIENCE Ε. H. Ahrens, Jr. AUTHOR INDEX—SUBJECT INDEX Volume 5 HYPOTHALAMIC CONTROL OF THE SECRETION OF ADENOHYPOPHYSIAL HORMONES Roger G utile min ADRENOCORTICAL CONTROL OF EPINEPHRINE SYNTHESIS IN HEALTH AND DISEASE R. J. Wurtman and L. A. Pohorecky THE RELATIONSHIP BETWEEN ANGIOTENSIN AND ALDOSTERONE G. W. Boyd and W. S. Peart THE METABOLIC INFLUENCE OF PROGESTINS Richard L. Landau and James T. Poulos THE THYMUS GLAND: EXPERIMENTAL AND CLINICAL STUDIES OF ITS ROLE IN THE DEVELOPMENT AND EXPRESSION OF IMMUNE FUNCTION Allan L. Goldstein and Abraham White CONTROL OF GLUCOSE METABOLISM IN THE HUMAN FETUS AND NEWBORN INFANT Peter A. J. Adam HUMAN ADIPOSE TISSUE DYNAMICS AND REGULATION Per Björntorp and Jan Östman CORONARY DISEASE AND CARBOHYDRATE AND FAT ABNORMALITIES Michael V. Herman and Richard Gorlin AUTHOR INDEX—SUBJECT INDEX
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