S m i t h ’S Anesthesia Infants for Children and E i g h t h E d i t i o n Peter J. davis, Md, FAAP Professor Department of Anesthesiology Department of Pediatrics University of Pittsburgh School of Medicine; Anesthesiologist-in-Chief Children’s Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania Franklyn P. Cladis, Md Assistant Professor Department of Anesthesiology University of Pittsburgh School of Medicine Children’s Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania Etsuro K. Motoyama, Md, FAAP Professor Emeritus Department of Anesthesiology Department of Pediatrics (Pulmonology) University of Pittsburgh School of Medicine; Former Director, Pediatric Pulmonology Laboratory Children’s Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania 1600 John F. Kennedy Blvd. Ste 1800 Philadelphia, PA 19103-2899 SMITH’S ANESTHESIA FOR INFANTS AND CHILDREN ISBN: 978-0-323-06612-9 Copyright © 2011 by Mosby, Inc., an affiliate of Elsevier Inc. 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Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods, they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Previous editions copyrighted 1959, 1963, 1968, 1980, 1990, 1996, 2006 International Standard Book Number 978-0-323-06612-9 Acquisitions Editor: Natasha Andjelkovic Developmental Editor: Julie Mirra Publishing Services Manager: Anne Altepeter Team Manager: Radhika Pallamparthy Senior Project Manager: Cheryl A. Abbott Project Manager: Antony Prince Design Direction: Steven Stave Printed in the United States of America Last digit is the print number: 9 8 7 6 5 4 3 2 1 Dr. Robert Moors Smith The eighth edition of Smith’s Anesthesia for Infants and physiological monitoring. By using a stethoscope taped on the Children is dedicated to Dr. Robert Moors Smith, who died on chest wall over the trachea and heart, Dr. Smith could assess November 25, 2009, 2 weeks before he would have been 97. ongoing changes in heart and breath sounds. Furthermore, The eulogy published by the Harvard Medical School’s Office Dr. Smith, together with Ms. Betty Lank, his chief nurse anes- of Communications began with this statement: “The Harvard thetist, developed a homemade latex infant blood pressure cuff Medical School flag is at half-mast today in memory of Robert (referred to as the Smith cuff) and advocated its routine use M. Smith, MD, Clinical Professor of Anesthesia, former Chief for patient safety when inhaled anesthetics consisted of diethyl- of Anesthesiology at Children’s Hospital Boston and pioneer in ether and cyclopropane. These advancements were early steps clinical anesthesiology in children.” This was an extraordinary in the development of elaborate physiological monitoring sys- tribute from an institution that has produced literally hundreds tems that are essential for safe anesthesia care today. of world leaders in medicine. In 1959, Dr. Smith published the first comprehensive text- Dr. Smith was one of the most distinguished pioneers of mod- book for pediatric anesthesia, entitled Anesthesia for Infants and ern anesthesia for children in the world. In the United States Children. It was well received among practitioners and trainees he was considered the “Father of Pediatric Anesthesiology.” in pediatric anesthesia and soon became a classic, often referred During his tenure at Children’s Hospital Boston, Dr. Smith was to as the “Bible of Pediatric Anesthesia.” For the ensuing 20 years a superb and compassionate clinician and educator who con- until his retirement from Harvard in 1980, Dr. Smith revised and tinually advanced practices in pediatric anesthesia and kept expanded the book through the fourth edition, as he kept abreast abreast with the fast progress of increasingly complex surgery with the rapid progress in the practice and science of pediat- on smaller and younger patients. He was an early advocate of ric anesthesia and other pediatric surgical specialties. Shortly compassionate patient safety—more than 30 years before the thereafter, Dr. Smith asked the current editors to assume the term even existed. editorship. To continue his vision, the book was modified and Along with Dr. Margo Deming of Philadelphia, Dr. Smith expanded to a multi-authored volume and was renamed Smith’s was an early supporter of endotracheal intubation with ster- Anesthesia for Infants and Children in Dr. Smith’s honor. The ile and child-appropriate–sized tubes to prevent aspiration fifth through the seventh editions were published between and postintubation croup. He also encouraged the wrapping of 1990 and 2006. With this eighth edition, Smith’s Anesthesia for small children to prevent heat loss. In the early 1950s when the Infants and Children has been in publication for more than half monitoring of infants and children consisted of visual observa- a century, making it the longest ongoing textbook of pediatric tion of the patient and intermittent palpation of the patient’s anesthesiology in the world. It has been a great honor and privi- radial pulse, Dr. Smith pioneered a new approach of continuous lege for us to carry on Dr. Smith’s legacy. iii C ontributors Ann G. Bailey, MD Adrian Bosenberg, MB ChB, FFA(SA) Professor, Anesthesiology and Pediatrics Professor, University of Washington School University of North Carolina of Medicine; Chapel Hill, North Carolina Director, Regional Anesthesia Services Seattle Children’s Hospital David Barinholtz, MD Seattle, Washington President and CEO, Mobile Anesthesiologists, LLC Chicago, Illinois Barbara W. Brandom, MD Professor, Department of Anesthesiology Victor C. Baum, MD University of Pittsburgh School of Medicine; Professor, Anesthesiology and Pediatrics Attending Physician, Department of Anesthesiology Executive Vice-Chair, Department of Anesthesiology Children’s Hospital of Pittsburgh of UPMC; Director, Cardiac Anesthesia Director, North American Malignant Hyperthermia Registry University of Virginia of MHAUS Charlottesville, Virginia Pittsburgh, Pennsylvania David S. Beebe, MD Claire Brett, MD Professor, Department of Anesthesiology Professor, Clinical Anesthesia and Pediatrics University of Minnesota Department of Anesthesiology and Perioperative Care Minneapolis, Minnesota University of California, San Francisco San Francisco, California Kumar G. Belani, MBBS, MS Professor, Departments of Anesthesiology, Medicine, Robert B. Bryskin, MD and Pediatrics Regional Anesthesia Coordinator University of Minnesota Nemours Children’s Hospitals; Minneapolis, Minnesota Assistant Professor, Anesthesiology College of Medicine, Mayo Clinic Richard Berkowitz, MD Jacksonville, Florida Chairman and Medical Director, Department of Anesthesiology and Pain Medicine Patrick Callahan, MD Community Hospital Assistant Professor of Anesthesiology Munster, Indiana; University of Pittsburgh School of Medicine Visiting Associate Professor, Department of Anesthesiology Children’s Hospital of Pittsburgh of UPMC and Pediatrics Pittsburgh, Pennsylvania University of Illinois College of Medicine Chicago, Illinois Franklyn P. Cladis, MD Assistant Professor Bruno Bissonnette, MD, FRCPC Department of Anesthesiology Professor Emeritus of Anesthesia University of Pittsburgh School of Medicine University of Toronto Children’s Hospital of Pittsburgh of UPMC Toronto, Ontario; Pittsburgh, Pennsylvania Founder and President, Children of the World Anesthesia Foundation Rimouski, Quebec iv Contributors v David E. Cohen, MD Demetrius Ellis, MD Associate Professor, Anesthesiology and Critical Care Professor, Nephrology and Pediatrics and Pediatrics University of Pittsburgh School of Medicine; University of Pennsylvania; Director, Pediatric Nephrology Perioperative Medical Director, The Children’s Hospital Children’s Hospital of Pittsburgh of UPMC of Philadelphia Pittsburgh, Pennsylvania Philadelphia, Pennsylvania Jeffrey M. Feldman, MD, MSE Ira Todd Cohen, MD, MEd Division Chief, General Anesthesia Professor, Anesthesiology and Pediatrics Children’s Hospital of Philadelphia; Director of Education, Department of Anesthesiology Associate Professor, Clinical Anesthesia and Pain Medicine University of Pennsylvania School of Medicine Children’s National Medical Center Philadelphia, Pennsylvania Washington, DC Kathryn Felmet, MD Andrew Davidson, MBBS, MD Assistant Professor, Critical Care Medicine and Pediatrics Associate Professor, University of Melbourne; University of Pittsburgh School of Medicine Staff Anaesthetist, Royal Children’s Hospital; Children’s Hospital of Pittsburgh of UPMC Head, Clinical Research Development Pittsburgh, Pennsylvania Murdoch Children’s Research Institute Melbourne, Victoria, Australia John E. Fiadjoe, MD Assistant Professor, Anesthesia Jessica Davis, BA, JD, LLM Children’s Hospital of Philadelphia Adjunct Professor, Widener University School of Law Philadelphia, Pennsylvania Wilmington, Delaware Jonathan D. Finder, MD Peter J. Davis, MD, FAAP Professor of Pediatrics Professor University of Pittsburgh School of Medicine Department of Anesthesiology Clinical Director, Pulmonary Medicine Department of Pediatrics Children’s Hospital of Pittsburgh of UPMC University of Pittsburgh School of Medicine; Pittsburgh, Pennsylvania Anesthesiologist-in-Chief Children’s Hospital of Pittsburgh of UPMC Randall P. Flick, MD, MPH, FAAP Pittsburgh, Pennsylvania Associate Professor of Anesthesiology Chair, Division of Pediatric Anesthesiology Duncan de Souza, MD, FRCP(C) Medical Director, Eugenio Litta Children’s Hospital Assistant Professor, Anesthesiology and Pediatrics Mayo Clinic Department of Anesthesiology Rochester, Minnesota University of Virginia Charlottesville, Virginia Michelle Fortier, PhD Licensed Psychologist Nina Deutsch, MD Center for the Advancement of Pediatric Health Assistant Professor, Anesthesiology and Pediatrics University of California Irvine School of Medicine; Children’s National Medical Center Department of Anesthesiology and Perioperative Care Washington, DC Center for Pain Management Orange, California James A. DiNardo, MD, FAAP Associate Professor of Anesthesia Salvatore R. Goodwin, MD Harvard Medical School; Associate Professor, Anesthesiology Senior Associate in Cardiac Anesthesia Mayo Medical School Program Director, Pediatric Cardiac Anesthesia Fellowship Rochester, Minnesota; Children’s Hospital Boston Chairman, Department of Anesthesia Boston, Massachusetts Nemours Children’s Clinic Jacksonville, Florida Peter Ehrlich, MD, Msc, RCPS(C), FACS Associate Professor of Surgery, Section of Pediatric Surgery George A. Gregory, MD University of Michigan Medical School; Professor Emeritus of Anesthesia and Pediatrics Medical Director, Pediatric Trauma University of California, San Francisco University of Michigan CS Mott Children’s Hospital San Francisco, California Ann Arbor, Michigan vi Contributors Lorelei Grunwaldt, MD Nathalia Jimenez, MD, MPH Assistant Professor of Surgery Assistant Professor, Department of Anesthesiology University of Pittsburgh School of Medicine and Pain Medicine Division of Pediatric Plastic Surgery University of Washington School of Medicine Children’s Hospital of Pittsburgh of UPMC Seattle Children’s Hospital Pittsburgh, Pennsylvania Seattle, Washington Dawit T. Haile, MD Lori T. Justice, MD, FAAP Instructor of Anesthesiology Clinical Staff Pediatric Anesthesiologist Mayo Clinic Children’s Anesthesiologists, PC Rochester, Minnesota East Tennessee Children’s Hospital Knoxville, Tennessee Steven Hall, MD Arthur C. King Professor of Pediatric Anesthesia Zeev N. Kain, MD, MBA Feinberg School of Medicine Professor, Anesthesiology and Pediatrics and Psychiatry Northwestern University; and Human Behavior Anesthesiologist-in-Chief Chair, Department of Anesthesiology and Children’s Memorial Hospital Perioperative Care Chicago, Illinois Associate Dean of Clinical Operations, School of Medicine University of California, Irvine Gregory Hammer, MD Orange, California Professor, Anesthesia and Pediatrics Stanford University School of Medicine; Evan Kharasch, MD, PhD Associate Director, Pediatric ICU Vice Chancellor for Research Director, Pediatric Anesthesia Research Russell D. and Mary B. Shelden Professor Lucile Packard Children’s Hospital at Stanford of Anesthesiology Stanford, California Director, Division of Clinical and Translational Research Department of Anesthesiology; Michael W. Hauser, MD Professor of Biochemistry and Molecular Biophysics Staff Anesthesiologist Washington University in St. Louis Cleveland Clinic St. Louis, Missouri Cleveland, Ohio Sabine Kost-Byerly, MD, FAAP Eugenie S. Heitmiller, MD Director, Pediatric Pain Management Associate Professor, Anesthesiology and Pediatrics Department of Anesthesiology and Critical Care Department of Anesthesiology and Critical Care Medicine Medicine The Johns Hopkins University School of Medicine; The Johns Hopkins Hospital; Vice Chairman for Clinical Affairs Associate Professor of Anesthesiology Department of Anesthesiology and Critical Care Medicine The Johns Hopkins University School of Medicine The Johns Hopkins Hospital Baltimore, Maryland Baltimore, Maryland Elliot J. Krane, MD Andrew Herlich, DMD, MD Professor, Department of Anesthesia and Pediatrics Professor of Anesthesia, Department of Anesthesiology Stanford University School of Medicine University of Pittsburgh School of Medicine; Stanford, California; Chief of Anesthesia, UPMC Mercy Hospital Director of Pain Management Pittsburgh, Pennsylvania Lucile Packard Children’s Hospital at Stanford Palo Alto, California Robert S. Holzman, MD, FAAP Associate Professor of Anesthesia Barry D. Kussman, MBBCh, FFA (SA) Harvard Medical School; Assistant Professor of Anesthesia Senior Associate, Perioperative Anesthesia Harvard Medical School; Children’s Hospital Boston Senior Associate in Cardiac Anesthesia Boston, Massachusetts Children’s Hospital Boston Boston, Massachusetts Elizabeth A. Hunt, MD, MPH, PhD Assistant Professor, Department of Anesthesiology and Critical Ira S. Landsman, MD Care Medicine Associate Professor, Department of Anesthesiology The Johns Hopkins University School of Medicine; and Pediatrics; Drs. David S. and Marilyn M. Zamierowski Director Chief, Division of Pediatric Anesthesiology The Johns Hopkins Medicine Simulation Center Vanderbilt University Medical Center Baltimore, Maryland Nashville, Tennessee Contributors vii Ronald S. Litman, DO George M. McDaniel, MD, MS Attending Anesthesiologist Assistant Professor of Pediatrics and Internal The Children’s Hospital of Philadelphia; Medicine Professor, Anesthesiology and Pediatrics Director, Pediatric Electrophysiology University of Pennsylvania School of Medicine University of Virginia Philadelphia, Pennsylvania Charlottesville, Virginia Joseph Losee, MD, FACS, FAAP Francis X. McGowan, Jr., MD Professor of Surgery and Pediatrics Professor of Anesthesia University of Pittsburgh School of Medicine Harvard Medical School; Chief, Division Pediatric Plastic Surgery Chief, Division of Cardiac Anesthesia Children’s Hospital of Pittsburgh of UPMC Director, Anesthesia and Critical Care Pittsburgh, Pennsylvania Medicine Research Laboratory Igor Luginbuehl, MD Children’s Hospital Boston Associate Professor of Anesthesia Boston, Massachusetts Department of Anesthesia and Pain Medicine The Hospital for Sick Children Toronto, Ontario Constance L. Monitto, MD Assistant Professor, Anesthesiology and Critical Anne M. Lynn, MD Care Medicine Professor, Department of Anesthesiology The Johns Hopkins University School and Pain Medicine of Medicine Adjunct Professor, Pediatrics Baltimore, Maryland University of Washington School of Medicine Seattle Children’s Hospital Philip G. Morgan, MD Seattle, Washington Professor, Department of Anesthesiology University of Washington; Seattle Children’s Research Institute Thomas J. Mancuso, MD Seattle, Washington Associate Professor of Anesthesia Harvard Medical School; Senior Associate in Anesthesia Etsuro K. Motoyama, MD, FAAP Children’s Hospital Boston Professor Emeritus Boston, Massachusetts Department of Anesthesiology Department of Pediatrics (Pulmonology) University of Pittsburgh School of Medicine; Brian P. Martin, DMD Former Director, Pediatric Pulmonology Laboratory Clinical Assistant Professor Children’s Hospital of Pittsburgh of UPMC University of Pittsburgh School of Dental Pittsburgh, Pennsylvania Medicine; Chief, Division of Pediatric Dentistry Children’s Hospital of Pittsburgh of UPMC Julie Niezgoda, MD Pittsburgh, Pennsylvania Pediatric Anesthesiology Children’s Hospital Cleveland Clinic Keira Mason, MD Cleveland Clinic Associate Professor of Anesthesia Cleveland, Ohio Harvard Medical School; Director, Department of Radiology, Anesthesia, David M. Polaner, MD, FAAP and Sedation Professor of Anesthesiology and Pediatrics Children’s Hospital Boston University of Colorado School of Medicine; Boston, Massachusetts Attending Pediatric Anesthesiologist Chief, Acute Pain Service William J. Mauermann, MD Anesthesia Informatics Assistant Professor of Anesthesia The Children’s Hospital, Denver Mayo Clinic Aurora, Colorado Rochester, Minnesota Paul Reynolds, MD Lynne G. Maxwell, MD Uma and Sujit Pandit Professor and Chief of Pediatric Associate Professor of Anesthesiology and Critical Care Anesthesiology University of Pennsylvania Department of Anesthesiology Senior Anesthesiologist University of Michigan Children’s Hospital of Philadelphia Ann Arbor, Michigan Philadelphia, Pennsylvania viii Contributors Mark A. Rockoff, MD Kyle Soltys, MD Professor of Anesthesia Assistant Professor of Surgery Harvard Medical School; University of Pittsburgh School of Medicine Vice-Chairman, Department of Anesthesiology, Perioperative Thomas E. Starzl Transplant Institute and Pain Medicine Hillman Center For Pediatric Transplantation Children’s Hospital Boston Children’s Hospital of Pittsburgh of UPMC Boston, Massachusetts Pittsburgh, Pennsylvania Thomas Romanelli, MD, FAAP Sulpicio G. Soriano, MD Clinical Instructor, Harvard Medical School; Children’s Hospital Boston Endowed Chair in Pediatric Consultant Anesthesiologist Neuroanesthesia Shriners Burns Hospital Boston; Associate Professor of Anesthesia Assistant in Anesthesia Harvard Medical School; Massachusetts General Hospital Senior Associate, Department of Anesthesiology, Perioperative Boston, Massachusetts and Pain Medicine Children’s Hospital Boston Allison Kinder Ross, MD Boston, Massachusetts Associate Professor and Chief, Division of Pediatric Anesthesia Duke University Medical Center Brian P. Struyk, MD Durham, North Carolina Assistant Professor, Clinical Anesthesiology and Critical Care Joseph A. Scattoloni, MD University of Pennsylvania School of Medicine; Clinical Lecturer, Department of Anesthesia Director, Radiology Anesthesia Section of Pediatric Anesthesia Children’s Hospital of Philadelphia University of Michigan Health System Philadelphia, Pennsylvania Ann Arbor, Michigan Kevin J. Sullivan, MD Jamie McElrath Schwartz, MD Assistant Professor of Anesthesiology Assistant Professor, Departments of Anesthesiology and Rochester, Minnesota; Critical Care Medicine and Pediatrics Clinical Associate Professor of Pediatrics The Johns Hopkins University School of Medicine University of Florida Health Science Center Baltimore, Maryland Jacksonville, Florida; Staff Pediatric Anesthesiologist, Critical Care Physician, Robert J. Sclabassi, MD, PhD, DABNM, FASNM and Medical Director Attending Neurophysiologist Pediatric Intensive Care Unit Chief, Intraoperative Monitoring Service Wolfson Children’s Hospital West Penn Alleghany Health System Jacksonville, Florida Pittsburgh, Pennsylvania Jennifer Thomas, MBChB, FFA (SA), BSc (Ed) Victor L. Scott, II, BSc, MD Associate Professor, Department of Pediatric Anaesthesia Professor of Anesthesiology, Department of Anesthesiology Red Cross War Memorial Children’s Hospital University of Pittsburgh School of Medicine University of Cape Town Children’s Hospital of Pittsburgh of UPMC Cape Town, Western Cape, South Africa Pittsburgh, Pennsylvania Stevan P. Tofovic, MD, PhD, FAHA, FASN Donald H. Shaffner, MD Assistant Professor of Medicine Associate Professor, Department of Anesthesiology University of Pittsburgh School of Medicine Critical Care Medicine and Pediatrics Pittsburgh, Pennsylvania The Johns Hopkins University School of Medicine Baltimore, Maryland Kha Tran, MD Assistant Professor of Anesthesia and Critical Care Medicine Avinash C. Shukla, MBBS, FRCA University of Pennsylvania School of Medicine; Associate in Cardiac Anesthesia Attending Anesthesiologist and Clinical Director, Fetal Children’s Hospital Boston Anesthesia Team Boston, Massachusetts Children’s Hospital of Philadelphia Philadelphia, Pennsylvania †Robert M. Smith, MD Clinical Professor Emeritus of Anesthesia Donald C. Tyler, MD, MBA Harvard Medical School and Children’s Hospital Boston Associate Professor of Anesthesiology and Critical Care Boston, Massachusetts University of Pennsylvania Department of Anesthesiology and Critical Care Medicine The Hospital of the University of Pennsylvania and Children’s Hospital of Philadelphia †Deceased. Philadelphia, Pennsylvania Contributors ix Robert D. Valley, MD Jay A. Werkhaven, MD Professor of Anesthesiology and Pediatrics Associate Professor and Director, Pediatric Otolaryngology University of North Carolina School of Medicine Vanderbilt Bill Wilkerson Center for Otolaryngology Chapel Hill, North Carolina and Communication Sciences Vanderbilt University Monica S. Vavilala, MD Nashville, Tennessee Associate Professor, Department of Anesthesiology and Pain Medicine and Pediatrics Susan Woelfel, MD Adjunct Associate Professor, Neurological Surgery Associate Professor of Anesthesiology and Radiology University of Pittsburgh School of Medicine University of Washington; Children’s Hospital of Pittsburgh of UPMC Associate Director, Harborview Injury Prevention Pittsburgh, Pennsylvania and Research Center Seattle, Washington Myron Yaster, MD Richard J. Traystman Professor Lisa Vecchione, DMD, MDS Departments of Anesthesiology, Critical Care Medicine, Director, Orthodontic Services and Pediatrics Cleft-Craniofacial Center The Johns Hopkins University School of Medicine Children’s Hospital of Pittsburgh of UPMC; Baltimore, Maryland Assistant Clinical Professor of Surgery University of Pittsburgh School of Medicine Aaron L. Zuckerberg, MD Pittsburgh, Pennsylvania Director, Pediatric Anesthesia and Critical Care Medicine Director, Children’s Diagnostic Center Department Kerri M. Wahl, MD, FRCP(C) of Pediatrics and Anesthesia Associate Professor, Department Sinai Hospital; of Anesthesiology Assistant Professor, Department of Pediatrics Duke University Medical Center University of Maryland Medical School; Durham, North Carolina Director of Pediatric Anesthesia, Department of Anesthesia, NAPA/MD Baltimore, Maryland C s m ontributors to the upplemental aterial Cuneyt M. Alper, MD James G. Cain, MD Professor of Otolaryngology Visiting Associate Professor University of Pittsburgh School of Medicine Department of Anesthesiology Division of Pediatric Otolaryngology University of Pittsburgh School of Medicine Children’s Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania Pittsburgh, Pennsylvania Franklyn P. Cladis, MD Lawrence M. Borland, MD Assistant Professor Associate Professor Department of Anesthesiology Departments of Anesthesiology and Pediatrics University of Pittsburgh School of Medicine University of Pittsburgh School of Medicine Children’s Hospital of Pittsburgh of UPMC Children’s Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania Pittsburgh, Pennsylvania Peter J. Davis, MD, FAAP Robert B. Bryskin, MD Professor Regional Anesthesia Coordinator Department of Anesthesiology Nemours Children’s Hospitals; Department of Pediatrics Assistant Professor, Anesthesiology University of Pittsburgh School of Medicine; College of Medicine, Mayo Clinic Anesthesiologist-in-Chief Jacksonville, Florida Children’s Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania
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