SIDE-EFFECTS OF ACRYLIC CEMENT IMPLANTED INTO BONE

143 Pages·2017·19.33 MB·English

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SIDE-EFFECTS
OF ACRYLIC CEMENT
IMPLANTED
INTO BONE
R. FEITH

SIDE-EFFECTS OF ACRYLIC CEMENT
IMPLANTED INTO BONE
A histological, (micro)angiographic,
fluorescence-microscopic and autoradiographic
study in the rabbit femur
R.FEITH
From the Laboratory for Experimental Orthopaedics, Department of
Orthopaedics (head: Prof. Dr. Th. J. G. van Rens), Catholic University,
Nijmegen, The Netherlands.
SIDE-EFFECTS OF ACRYLIC CEMENT
IMPLANTED INTO BONE
A histological, (micro)angiographic,
fluorescence-microscopic and autoradiographic
study in the rabbit femur
PROMOTOR:
PROF. DR. TH. J. G. VAN RENS
CO-REFERENT:
DR. T. J. J. H. SLOOFF
SIDE-EFFECTS OF ACRYLIC CEMENT
IMPLANTED INTO BONE
A histological, (micro)angiographic,
fluorescence-microscopic and autoradiographic
study in the rabbit femur
PROEFSCHRIFT
TER VERKRIJGING VAN DE GRAAD VAN DOCTOR IN DE
GENEESKUNDE AAN DE KATHOLIEKE UNIVERSITEIT TE NIJMEGEN,
OP GEZAG VAN DE RECTOR MAGNIFICUS
PROF. MR. F. J. F. M. DUYNSTEE,
VOLGENS BESLUIT VAN HET COLLEGE VAN DECANEN
IN HET OPENBAAR TE VERDEDIGEN OP
VRIJDAG 12 DECEMBER 1975 DES NAMIDDAGS TE 4 UUR
DOOR
RHIJNVIS FEITH
GEBOREN TE 'S-GRAVENHAGE
1975
DRUKKERIJ BRAKKENSTEIN, NIJMEGEN
Translated by: Th. van Winsen
The publication of this study was financially supported by grants from the
Jan Dekkerstichting and Dr. Ludgardine Bouwmanstichting
and Hippocrates Studiefonds.
This thesis is also published as Supplementum No. 161 to the
Acta Orthopaedica Scandinavica.
To Annelies
and to the memory of
my first and finest teacher,
my grandfather
Jonkheer J. M. de Jonge, CE.
ACKNOWLEDGEMENTS
To do experimental work in addition to normal clinical daily duties
is made possible only by the know-how, help and positive criticism made
available by other workers, scientific or otherwise. All who in this way
have contributed to the completion of this thesis receive my heartfelt
thanks.
In particular I have made grateful use of the actual help and advice
of J. R. de Wijn Chem. E. (Department of Dental Materials), Dr F. W.
Rhinelander (Professor of Orthopaedic Research, University of Arkansas,
Little Rock, USA), R. A. M. J. Claessens Chem. D. (Department of Nuclear
Medicine), J. R. Bakker, dispensing chemist and J. Ellul, anesthesiologist.
The original ideas and helpfulness of Messrs. T. J. M. Arnoldussen
(Instrument Workshop), A. J. Peters, Th. H. M. Arts, P. H. G. Philipsen
and G. J. T. Gratters (Central Animal Laboratory) have been of much
importance to me.
Mrs Mieke H. J. Jacobs-Van den Hombergh and later Miss Diny H. J.
Versleyen and Miss Gemma M. J. Bongers (Laboratory for Experimental
Orthopaedics) prepared the specimens, and the autoradiograms were made
with the technical assistance of N. V. M. Rijntjes (Dispensary). Indispen
sable assistance was given by F. E. Schrijer (Instrumental Service) in fluor
escence photomicrography. The drawings were supplied by the department
of Medical Illustration (head: J. J. M. de Bekker). I have greatly ap
preciated the efforts of the department of Medical Photography (head:
A. T. A. Rcynen), which supplied the photomicrographs and advice in
the lay-out of this thesis. The manuscript was typed with great care
by Miss Irene A. Keizer and Miss Petra M. G. Jansen.