Schizophrenia and related disorders PDF
Preview Schizophrenia and related disorders
i Schizophrenia and Related Disorders ii iii Schizophrenia and Related Disorders Edited by Michael J. Marcsisin, MD Assistant Professor Department of Psychiatry University of Pittsburgh School of Medicine Jessica M. Gannon, MD Assistant Professor Department of Psychiatry University of Pittsburgh School of Medicine Jason B. Rosenstock, MD Associate Professor Department of Psychiatry University of Pittsburgh School of Medicine Director, Medical Student Education Western Psychiatric Institute and Clinic 1 iv 1 Oxford University Press is a department of the University of Oxford. It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. Oxford is a registered trade mark of Oxford University Press in the UK and certain other countries. Published in the United States of America by Oxford University Press 198 Madison Avenue, New York, NY 10016, United States of America. © Oxford University Press 2017 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of Oxford University Press, or as expressly permitted by law, by license, or under terms agreed with the appropriate reproduction rights organization. Inquiries concerning reproduction outside the scope of the above should be sent to the Rights Department, Oxford University Press, at the address above. You must not circulate this work in any other form and you must impose this same condition on any acquirer. Library of Congress Cataloging-in-Publication Data Names: Marcsisin, Michael J., editor. | Gannon, Jessica M., editor. | Rosenstock, Jason, editor. Title: Schizophrenia and related disorders / edited by Michael J. Marcsisin, Jessica M. Gannon, Jason B. Rosenstock. Other titles: Pittsburgh pocket psychiatry series. Description: Oxford ; New York : Oxford University Press, [2016] | Series: Pittsburgh pocket psychiatry series | Includes bibliographical references. Identifiers: LCCN 2016009493 (print) | LCCN 2016010135 (ebook) | ISBN 9780199331505 (pbk. : alk. paper) | ISBN 9780199331512 (U-pdf) | ISBN 9780199331529 (Epub) Subjects: | MESH: Schizophrenia Classification: LCC RC514 (print) | LCC RC514 (ebook) | NLM WM 203 | DDC 616.89/8—dc23 LC record available at http://lccn.loc.gov/2016009493 This material is not intended to be, and should not be considered, a substitute for medical or other professional advice. Treatment for the conditions described in this material is highly dependent on the individual circumstances. And, while this material is designed to offer accurate information with respect to the subject matter covered and to be current as of the time it was written, research and knowledge about medical and health issues is constantly evolving and dose schedules for medications are being revised continually, with new side effects recognized and accounted for regularly. Readers must therefore always check the product information and clinical procedures with the most up-to-date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulation. The publisher and the authors make no representations or warranties to readers, express or implied, as to the accuracy or completeness of this material. Without limiting the foregoing, the publisher and the authors make no representations or warranties as to the accuracy or efficacy of the drug dosages mentioned in the material. The authors and the publisher do not accept, and expressly disclaim, any responsibility for any liability, loss or risk that may be claimed or incurred as a consequence of the use and/or application of any of the contents of this material. 9 8 7 6 5 4 3 2 1 Printed by Sheridan Books, Inc., United States of America v v Series Introduction We stand on the threshold of a new golden age of clinical and behavioral neuroscience with psychiatry at its fore. With the Pittsburgh Pocket Psychiatry series, we intend to encompass the breadth and depth of our current understanding of human behavior in health and disease. Using the structure of resident didactic teaching, we will be able to ensure that each subject area relevant to practicing psychiatrists is detailed and described. New innovations in diagnosis and treatment will be reviewed and discussed in the context of existing knowledge, and each book in the series will propose new directions for scientific inquiry and discovery. The aim of the series as a whole is to integrate findings from all areas of medicine and neuroscience previously segregated as “mind” or “body,” “psychological” or “biological.” Thus, each book from the Pittsburgh Pocket Psychiatry series will stand alone as a standard text for anyone wishing to learn about a specific subject area. The series will be the most coherent and flexible learning resource available. David Kupfer, MD Michael Travis, MD Michelle Horner, DO vi vii vii Contents Contributors ix 1 History and Phenomenology of Schizophrenia and Related Psychoses 1 Michael J. Marcsisin and Jessica M. Gannon 2 Diagnosis and Assessment of Schizophrenia and Related Psychoses 53 Jason B. Rosenstock 3 Epidemiology of Schizophrenia 89 Jaspreet S. Brar 4 Course, Prognosis, and Outcomes of Schizophrenia and Related Disorders 111 Konasale M. Prasad 5 Neurobiology of Schizophrenia 143 Gil D. Hoftman and Dean F. Salisbury 6 Somatic Treatments for Psychotic Disorders 185 Justin C. Ellison, Jason B. Rosenstock, and Michael J. Marcsisin 7 Psychosocial Treatment for Psychotic Disorders 247 Jessica M. Gannon and Shaun M. Eack Answers 293 Index 295 viii ix ix Contributors Jaspreet S. Brar, Michael J. Marcsisin, MD MD, PhD Department of Psychiatry Department of Psychiatry University of Pittsburgh School University of Pittsburgh of Medicine School of Medicine Western Psychiatric Institute Western Psychiatric Institute and Clinic and Clinic Pittsburgh, Pennsylvania Pittsburgh, Pennsylvania Konasale M. Prasad, MD Shaun M. Eack, PhD Department of Psychiatry University of Pittsburgh University of Pittsburgh School School of Social Work of Medicine Pittsburgh, Pennsylvania Western Psychiatric Institute Justin C. Ellison, and Clinic PharmD, BCPP Pittsburgh, Pennsylvania Department of Pharmacy Jason B. Rosenstock, MD University of Pittsburgh Department of Psychiatry School of Pharmacy University of Pittsburgh School Western Psychiatric Institute of Medicine and Clinic Western Psychiatric Institute Pittsburgh, Pennsylvania and Clinic Jessica M. Gannon, MD Pittsburgh, Pennsylvania Department of Psychiatry Dean F. Salisbury, PhD University of Pittsburgh Department of Psychiatry School of Medicine University of Pittsburgh School Western Psychiatric Institute of Medicine and Clinic Western Psychiatric Institute Pittsburgh, Pennsylvania and Clinic Gil D. Hoftman, Pittsburgh, Pennsylvania MD, PhD Department of Psychiatry University of Pittsburgh School of Medicine Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania
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