Schizophrenia and Comorbid Conditions: Diagnosis and Treatment

257 Pages·2001·3.274 MB·English

by  Michael Y. Hwang, Paul C. Bermanzohn

SCHIZOPHRENIA AND
COMORBID CONDITIONS
Diagnosis and Treatment
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SCHIZOPHRENIA AND
COMORBID CONDITIONS
Diagnosis and Treatment
Edited by
Michael Y. Hwang, M.D.
Paul C. Bermanzohn, M.D.
Washington, DC
London, England
Note: The authors have worked to ensure that all information in this book con-
cerning drug dosages, schedules, and routes of administration is accurate as of the
time of publication and consistent with standards set by the U.S. Food and Drug
Administration and the general medical community. As medical research and
practice advance, however, therapeutic standards may change. For this reason and
because human and mechanical errors sometimes occur, we recommend that read-
ers follow the advice of a physician who is directly involved in their care or the care
of a member of their family.
Books published by the American Psychiatric Press, Inc., represent the views and
opinions of the individual authors and do not necessarily represent the policies
and opinions of the Press or the American Psychiatric Association.
Copyright © 2001 American Psychiatric Press, Inc.
ALL RIGHTS RESERVED
Manufactured in the United States of America on acid-free paper
First Edition
04 03 02 01 4 3 2 1
American Psychiatric Press, Inc.
1400 K Street, N.W.
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www.appi.org
Library of Congress Cataloging-in-Publication Data
Schizophrenia and comorbid conditions : diagnosis and treatment / edited
by Michael Y. Hwang, Paul C. Bermanzohn.—1st ed.
p. ; cm. — (Clinical practice)
Includes bibliographical references and index.
ISBN 0-88048-771-2 (alk. paper)
1. Schizophrenia. 2. Comorbidity. I. Hwang, Michael Y. II. Bermanzohn,
Paul C. III. Clinical practice (Unnumbered)
[DNLM: 1. Schizophrenia—diagnosis. 2. Comorbidity. 3. Schizophrenia—
therapy. WM 203 S33743 2001]
RC514 .S33426 2001
616.89′82—dc21
00-058661
British Library Cataloguing in Publication Data
A CIP record is available from the British Library.
Contents
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
Introduction to the Clinical Practice Series . . . . . . . . . . . . . . . . . . . . . . . . xi
Judith H. Gold, C.M., M.D., F.R.C.P.C., F.R.A.N.Z.C.P.
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiii
Michael Y. Hwang, M.D.
Paul C. Bermanzohn, M.D.
Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xvii
1 Hierarchy, Reductionism, and “Comorbidity” in the
Diagnosis of Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Paul C. Bermanzohn, M.D.
Linda Porto, M.S.N., R.N., C.S.
Samuel G. Siris, M.D.
Roz Stronger, M.A.
Michael Y. Hwang, M.D.
Simcha Pollack, Ph.D.
2 Depression in the Course of Schizophrenia . . . . . . . . . . . . . . . . . . . . . . .31
Samuel G. Siris, M.D.
3 Obsessive-Compulsive Symptoms in Patients With Schizophrenia . . . . . .57
Michael Y. Hwang, M.D.
Paul C. Bermanzohn, M.D.
Lewis A. Opler, M.D., Ph.D.
4 Panic Symptoms in PatientsWithSchizophrenia . . . . . . . . . . . . . . . . . . .79
Richard J. Pitch, M.D.
Paul C. Bermanzohn, M.D.
Samuel G. Siris, M.D.
5 Medical and Surgical Illness in PatientsWith Schizophrenia . . . . . . . . . .95
John H. Gilmore, M.D.
L. Fredrik Jarskog, M.D.
T. Scott Stroup, M.D., M.P.H.
6 Pregnancy in Patients With Schizophrenia . . . . . . . . . . . . . . . . . . . . . .113
John H. Gilmore, M.D.
L. Fredrik Jarskog, M.D.
T. Scott Stroup, M.D., M.P.H.
7 Cognitive Impairment in OlderSchizophrenia Patients . . . . . . . . . . . . .125
J. Akiko Gladsjo, Ph.D.
John H. Eastham, Pharm.D.
Dilip V. Jeste, M.D.
8 Aggression and Violence in PatientsWithSchizophrenia . . . . . . . . . . .149
Leslie Citrome, M.D., M.P.H.
Jan Volavka, M.D., Ph.D.
9 Substance Abuse in PatientsWithSchizophrenia . . . . . . . . . . . . . . . . . .187
Douglas Ziedonis, M.D., M.P.H.
Connie Nickou, Psy.D.
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .223
Contributors
Paul C. Bermanzohn, M.D.
Associate Professor of Clinical Psychiatry, Albert Einstein College of Med-
icine, New York, New York; Medical Director, Queen’s Day Center, Hill-
side Hospital/North Shore–Long Island Jewish Health System, Jamaica,
New York
Leslie Citrome, M.D., M.P.H.
Clinical Associate Professor of Psychiatry, New York University, New
York, New York; Director, Clinical Research and Evaluation Facility,
Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York
John H. Eastham, Pharm.D.
Clinical Specialist, Department of Pharmacy, Naval Medical Center San
Diego, San Diego, California; Clinical Assistant Professor of Pharmacy
Practice, Western University of Health Sciences, Pomona, California
John H. Gilmore, M.D.
Associate Professor, Department of Psychiatry, University of North Caro-
lina School of Medicine, Chapel Hill
J. Akiko Gladsjo, Ph.D.
Research Fellow in Geriatric Psychiatry, University of California, San
Diego; San Diego VA Medical Center, San Diego, California
Michael Y. Hwang, M.D.
Associate Professor of Psychiatry, Robert Wood Johnson Medical School—
UMDNJ, Piscataway, New Jersey; Director of Schizophrenia Research,
East Orange VAMC, East Orange, New Jersey
L. Fredrik Jarskog, M.D.
Assistant Professor, Department of Psychiatry, University of North Caro-
lina School of Medicine, Chapel Hill
vii
viii Schizophrenia and Comorbid Conditions
Dilip V. Jeste, M.D.
Professor of Psychiatry and Neurosciences, University of California, San
Diego; San Diego VA Medical Center, San Diego, California
Connie Nickou, Psy.D.
Clinical Instructor, Department of Psychiatry, Yale University, New
Haven, Connecticut
Lewis A. Opler, M.D., Ph.D.
Adjunct Professor of Psychiatry, Columbia University College of Physi-
cians and Surgeons, New York, New York; Director of Research Division,
New York State Office of Mental Health, New York, New York
Richard J. Pitch, M.D.
Private practice, Melville, New York
Simcha Pollack, Ph.D.
Formerly Biostatistician, Department of Research, Hillside Hospital/
North Shore–Long Island Jewish Health System, Jamaica, New York; cur-
rently Professor of Statistics, Department of Computer Information Sys-
tems and Decision Sciences, St. John’s University, Jamaica, New York
Linda Porto, M.S.N., R.N., C.S.
Research Nurse, Department of Research, Hillside Hospital/North Shore–
Long Island Jewish Health System, Glen Oaks, New York
Samuel G. Siris, M.D.
Professor of Psychiatry, Albert Einstein College of Medicine, New York,
New York; Director, Division of Continuing Psychiatric Services for
Schizophrenia and Related Conditions, Hillside Hospital/North Shore–
Long Island Jewish Health System, Glen Oaks, New York
Roz Stronger, M.A.
Application Support Specialist, Hillside Hospital/North Shore–Long
Island Jewish Health System, Glen Oaks, New York
T. Scott Stroup, M.D., M.P.H.
Assistant Professor, Department of Psychiatry, University of North Caro-
lina School of Medicine, Chapel Hill
Contributors ix
Jan Volavka, M.D., Ph.D.
Professor of Psychiatry, New York University, New York, New York; Chief,
Clinical Research Division, Nathan S. Kline Institute for Psychiatric
Research, Orangeburg, New York
Douglas Ziedonis, M.D., M.P.H.
Associate Professor and Director, Division of Addiction Psychiatry, Robert
Wood Johnson Medical School, Piscataway, New Jersey