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Saunders Nursing Drug Handbook 2019 PDF

3120 Pages·2018·10.81 MB·English
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Saunders Nursing Drug Handbook 2019 Robert J. Kizior, BS, RPh Department of Pharmacy, Alexian Brothers Medical Center, Elk Grove Village, Illinois Keith J. Hodgson, RN, BSN, CCRN Staff Nurse, Intensive Care Unit, Former Staff Nurse, Emergency Department, St. Joseph’s Hospital, Tampa, Florida Table of Contents Cover image Title page Copyright IFC Newly Approved Medications Author Biographies Reviewers Consultants Acknowledgments Dedication Preface Drug Classification Contents Allergic Rhinitis Preparations Beta-Adrenergic Blockers Calcium Channel Blockers Diuretics H2 Antagonists Immunosuppressive Agents Laxatives Multiple Sclerosis Obesity Management Parkinson's Disease Treatment Sedative-Hypnotics Vitamins A B C D E F G H I K L M N O P Q R S T U V W Z Appendix A Appendix B Appendix C Appendix D Appendix E Appendix F Appendix G Appendix H Appendix I Appendix J Appendix K Appendix L Appendix M evolve Index Commonly Used Abbreviations Copyright 3251 Riverport Lane St. Louis, Missouri 63043 SAUNDERS NURSING DRUG HANDBOOK 2019 ISBN: 978-0-323-60885-5 ISSN: 1098-8661 Copyright © 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004, 2003, 2002, 2001, 2000, 1999, 1998, 1997, 1996, 1995, 1994, 1993 by Elsevier Inc. All rights reserved. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notices Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors, or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence, or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. ISBN: 978-0-323-60885-5 Executive Content Strategist: Sonya Seigafuse Content Development Manager: Lisa Newton Senior Content Development Specialist: Tina Kaemmerer, Charlene Ketchum Publishing Services Manager: Julie Eddy Project Manager: Mike Sheets Design Direction: Ryan Cook Printed in the United States of America Last digit is the print number: 9 8 7 6 5 4 3 2 1 IFC IV Compatibilities The IV compatibility table provides data when 2 or more medications are given in a Y-site of administration. The data in this table largely represent physical incompatibilities (e.g., haze, precipitate, change in color). Therapeutic incompatibilities have not been included, so when using the table, professional judgement should be exercised. C Physically compatible via Y-site administration. I Physically incompatible. N Information on compatibility not available or conflicting Dextrose 5% Sodium Chloride Acyclovir Amikacin Amiodarone Anidulafungin Argatroban Azithromycin Acyclovir C C — C N C N Amikacin C C C — C C N Amiodarone C C N C — N I Anidulafungin C C C C N — N Argatroban C C N N I N — Azithromycin C C N I N N N Aztreonam C C I C N N N Bivalirudin C C N C I N N Bumetanide C C N N N N N Calcium Gluconate C C N C C N N Cefazolin C C C C I C N Cefepime C C N C N C N Ceftaroline Fosamil C C C C C N N Ceftriaxone C C C C C C N Ciprofloxacin C C N C C C N Clevidipine C C N N N N N Clindamycin C C C C C C N Daptomycin I C N C N N N Dexamethasone C C C C N C N Dexmedetomidine C C N C C N N Diltiazem C C I C N N C Diphenhydramine C C C C N N C Dobutamine C C I N C C C Dopamine C C I N C C C Enalapril C C N C N N N Epinephrine C C N C C C N Eptifibatide C C N N C N C Esmolol C C N C C N N Famotidine C C C N C C N Fluconazole C C C C C C N Furosemide C C N C C C C Gentamicin C C C N C C N Granisetron C C C C N N N Heparin C C C I I C N Hydrocortisone C C C C N C C Hydromorphone C C C C N N N Imipenem C C C N I C N Insulin N C N N C N N Labetalol C C N C C N N Levofloxacin C C I C N C N Linezolid C C C C N C N Lorazepam N C C C C N N Magnesium C C C C I N N Mannitol — — N C N N N Meropenem N C I N N C N Methylprednisolone C C C N C C N Metoclopramide C C C N N N N Metronidazole — — C N N C N Midazolam C C N C C C C Morphine C C C C C C C Nicardipine C C N C N N N Nitroglycerin C C N N C N C Nitroprusside C C N N I N C Norepinephrine C C N C C C C Octreotide C C N N N N N Ondansetron C C I C N N N Pantoprazole C C N I I C N Phenylephrine C C N N C C C Piperacillin/Tazobactam C C I N I C N Potassium Chloride C C C C C C N Propofol C C C I N N N Sodium Bicarbonate C C C C I I N Tigecycline C C N C N N N Tobramycin C C C N C C N Vancomycin C C C C C C N Vasopressin — C N N C N C Newly Approved Medications Abaloparatide (Tymlos) Treatment of postmenopausal women with osteoporosis at high risk for fracture Avelumab (Bavencio) A monoclonal antibody for metastatic Merkel cell carcinoma Betarixaban (Bevyxxa) Factor Xa inhibitor for prophylaxis of venous thromboembolism ∗Bezlotoxumab (Zinplava) A monoclonal antibody to reduce recurrence of C. difficile infection Brigatinib (Alunbrig) Treatment on NSCLC who have progressed or are intolerant to crizotinib Brodalumab (Sililq) An IL-17RA antagonist for moderate to severe plaque psoriasis ∗Cerliponase alfa (Brineura) Slow loss of ambulation tripeptidyl peptidase 1 deficiency Clevidipine (Cleviprex) Management of hypertension when oral therapy not feasible ∗Deflazacort (Emflaza) An oral corticosteroid for Duchenne muscular dystrophy Delafloxacin (Baxdela) A fluoroquinolone for treatment of skin and skin structure infections ∗Deutetrabenazine (Austedo) A VMAT2 inhibitor for chorea associated with Huntington’s disease ∗Dupilumab (Dupixent) An IL-4RA antagonist for moderate to severe eczema (atopic dermatitis) Durvalumab (Imfinzi) Treatment of locally advanced or metastatic urothelial carcinoma ∗Etelcalcetide (Parsabiv) A calcium sensing receptor agonist for secondary hyperparathyroidism in patients with chronic kidney disease on hemodialysis Guselkumab (Tremfya) Interleukin blocker for treatment of adulst with moderate to severe plaque psoriasis Ledipasvir/sofosbuvir (Harvoni) Treatment of chronic hepatitis C genotypes 1,4,5,6 Midostaurin (Rydapt) Kinase inhibitor for treatment of newly diagnosed acute myeloid leukemia Naldemedine (Symproic) An opioid antagonist for opioid-induced constipation Naloxegol (Movantik) Treatment of opioid induced constipation for chronic pain Neratinib (Nerlynx) Kinase inhibitor for extended adjuvant treatment of breast cancer Niraparib (Zejula) A PARP inhibitor for recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer Ocrelizumab (Ocrevus) A monoclonal antibody for relapsing or primary progressive forms of multiple sclerosis Olaratumab (Lartruvo) A PDGFR-alpha blocking antibody for soft tissue sarcoma Plecanatide (Trulance) A guanylate cyclase-C agonist for chronic idiopathic constipation Ponatinib (Iclusig) Kinase inhibitor for treatment of acute lymphoblastic and chronic myeloid leukemia Ribociclib (Kisqali) A kinase inhibitor for postmenopausal women with advanced breast cancer Rucaparib (Rubraca) An oral PARP inhibitor for certain types of advanced ovarian cancer Safinamide (Xadago) An MAO-B inhibitor for Parkinson’s patients experiencing “off” episodes Sarilumab (Kevzara) Treatment of moderate to severe active rheumatoid arthritis Sofosbuvir/velpatasvir/voxilaprevir (Vosevi) Fixed combination for treatment of chronic HCV genotypes 1, 2, 3, 4, 5 or 6 ∗Telotristat (Xermelo) An oral tryptophan hydroxylase inhibitor for carcinoid syndrome diarrhea Valbemazine (Ingrezza) A selective VMATZ inhibitor for the treatment of tardive dyskinesia Ziv-Aflibercept (Zaltrap) Treatment of colorectal cancer, metastatic ∗ Featured on Evolve only Author Biographies Robert (Bob) J. Kizior, BS, RPh Bob graduated from the University of Illinois School of Pharmacy and is licensed to practice in the state of Illinois. He has worked as a hospital pharmacist for more than 40 years at Alexian Brothers Medical Center in Elk Grove Village, Illinois—a suburb of Chicago. Bob is the Pharmacy Surgery Coordinator for the Department of Pharmacy, where he participates in educational programs for pharmacists, nurses, physicians, and patients. He plays a major role in coordinating pharmacy services in the OR satellite. Bob is a former adjunct faculty member at William Rainey Harper Community College in Palatine, Illinois. An avid sports fan, Bob also has eclectic tastes in music that range from classical, big band, rock ‘n’ roll, and jazz to country and western. Bob spends much of his free time reviewing the professional literature to stay current on new drug information. Keith J. Hodgson, RN, BSN, CCRN Keith was born into a loving family in Chicago, Illinois. His mother, Barbara B. Hodgson, was an author and publisher of several medication products, and her work has been a part of his life since he was a child. By the time he was 4 years old, Keith was already helping his mother with the drug cards by stacking the draft pages that were piled up throughout their home. Because of his mother’s influence, Keith contemplated becoming a nurse in college, but his mind was fully made up after he shadowed his sister in the Emergency Department. Keith received his Associates Degree in Nursing from Hillsborough Community College and his Bachelor of Science in Nursing from the University of South Florida in Tampa, Florida. Keith started his career in the Emergency Department and now works in the Trauma/Neurological/Surgical Intensive Care Unit at St. Joseph’s Hospital in Tampa, Florida.

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