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Sapira’s Art & Science of Bedside Diagnosis F E O U R T H D I T I O N Jane M. Orient, M.D. Clinical Lecturer in Medicine University of Arizona College of Medicine Tucson, Arizona FFMM..iinndddd ii 99//1199//22000099 11::0077::2255 PPMM Acquisitions Editor: Sonya Seigafuse Product Manager: Kerry Barrett Production Manager: Bridgett Dougherty Senior Manufacturing Manager: Benjamin Rivera Marketing Manager: Kimberly Schonberger Design Coordinator: Stephen Druding Production Service: SPi Technologies © 2010 by LIPPINCOTT WILLIAMS & WILKINS, a WOLTERS KLUWER business 530 Walnut Street Philadelphia, PA 19106 USA LWW.com All rights reserved. This book is protected by copyright. No part of this book may be reproduced in any form by any means, including photocopying, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their offi cial duties as U.S. government employees are not covered by the above-mentioned copyright. Printed in China Library of Congress Cataloging-in-Publication Data Orient, Jane M. Sapira’s art & science of bedside diagnosis / Jane M. Orient.—4th ed. p. ; cm. Includes bibliographical references and index. ISBN 978–1–60547–411–3 (alk. paper) 1. Physical diagnosis. 2. Medical history taking. I. Sapira, Joseph D., 1936– II. Title. III. Title: Sapira’s art and science of bedside diagnosis. IV. Title: Art & science of bedside diagnosis. V. Title: Art and science of bedside diagnosis. [DNLM: 1. Medical History Taking. 2. Physical Examination. WB 200 O69s 2010] RC76.S25 2010 616.07´54—dc22 2009030914 Care has been taken to confi rm the accuracy of the information presented and to describe generally accepted practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the publication. Application of the information in a particular situation remains the professional responsibility of the practitioner. The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accordance with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant fl ow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new or infrequently employed drug. Some drugs and medical devices presented in the publication have Food and Drug Administration (FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug or device planned for use in their clinical practice. To purchase additional copies of this book, call our customer service department at (800) 638–3030 or fax orders to (301) 223–2320. International customers should call (301) 223–2300. Visit Lippincott Williams & Wilkins on the Internet: at LWW.com. Lippincott Williams & Wilkins customer service representatives are available from 8:30 am to 6 pm, EST. 10 9 8 7 6 5 4 3 2 1 FFMM..iinndddd iiii 99//1199//22000099 11::0077::2255 PPMM C O N T E N T S Preface to the Fourth Edition VII The Evasive Patient 38 Preface to the First Edition VIII The Uncooperative (“Noncompliant”) Patient 39 Acknowledgments IX Dealing with Fantasies 40 The Patient Who Begins to Cry 40 1 Introduction 1 The Patient Who Is Undiagnosable 41 The Demanding Patient 41 How to Use This Book 1 The Patient Who Denies the Relevance of Psychologic A Disclaimer 2 Factors 42 Diagnostic Equipment of Purchase 2 The Science of Clinical Examination 4 APPENDIX 2.1 Abbreviated Cognitive Examination 42 The Art of Clinical Examination 5 APPENDIX 2.2 Reasons For Identifying the Patient with Dementia 42 Ethical Foundations 5 Defi nitions 6 APPENDIX 2.3 Answer to the Self-test on the CAGE Test 42 Further Reading 42 Evaluation of Diagnostic Signs: More Defi nitions 8 References 43 Evidence-based Medicine 13 APPENDIX 1.1 Answer to the Question on the Stethoscope 15 3 The History 44 APPENDIX 1.2 Answer to the Question on Incidence and Importance of the History 44 Prevalence 15 The Difference between Facts and Information 44 APPENDIX 1.3 Analysis of Example on Testing Sequence 15 Overview of History of Present Illness 44 APPENDIX 1.4 Answer to the Self-study Question on Prior and Chief Complaint 45 Posterior Probabilities 15 Dimensions of a Symptom 45 APPENDIX 1.5 Answer to the Self-study Question on NNT 15 Associated Symptoms 48 References 15 Abbreviated History in Trauma Patients 48 Elaboration of Selected Symptoms 48 2 The Interview 17 A Philosophical Interlude on “Diseases” and “Syndromes” 59 First Principles of the Interview 17 Use of Diagnostic Conclusions 59 Interviewing Style 17 Past Medical History 59 Assessing and Improving Your Interviewing Skills 22 Social History 60 Autognosis 24 Sexual History 61 Last Question in the Interview 25 A History of Abuse 63 The Psychodynamic Termination of the Physical Examination 25 Drug History 63 Notes on Offi ce-based Practice 25 Dietary and Nutritional History 64 Interviewing Patients Who Are Forgetful or Confused 26 A Note to the Student 65 Approach to the Elderly Patient 30 References 66 The Patient Who Seems to Be Changing His Story 31 The Patient Who Is Vague 31 4 The Case Record 68 The Patient Who May Be Addicted to Drugs or Behaviors 32 Introduction 68 The Patient Who May Be Involved in Illegal Activities 33 Model Outline of Gerry Rodnan, MD 70 The Patient Who May Have Other Legal Involvements 34 Comments on Historic Information 72 The Pseudopatient 34 General Considerations on Authoring the Medical Record 73 The Patient Who Might Have a Factitious Disease 34 Chief Complaint 73 Sexual Orientation 35 The “Problem-Oriented” Medical Record 74 The Patient Who Is a Member of a Subculture with Its Own History of the Present Illness 74 Jargon 35 Past Medical History 76 The Non–English-speaking Patient 35 Social History 76 The Patient Who Cannot Hear Well 36 Review of Systems 76 The Patient Who Cannot Read Well 36 Physical Examination 77 The Hostile Patient 36 Differential Diagnosis 80 The Patient Who Refers to Himself as a “Guinea Pig” 36 Laboratory Data 80 The Patient Who Will Only Be Examined by a “Real Bedside Presentation 81 Doctor” 37 APPENDIX 4.1 Forgacs Notation: Pathophysiologic The Patient Who Asks Personal Questions 37 Explanations 82 The Organ Recital (or “by the Way, Doctor…”) 37 APPENDIX 4.2 A Spanish–English Case Record 82 The Aphasic Patient 37 References 84 iii FFMM..iinndddd iiiiii 1100//11//22000099 22::2244::2211 PPMM iv Contents 5 General Appearance 85 Exophthalmos (Proptosis) 173 Extraocular Movements 173 A Method 85 The Sclera 176 Position and Posture 86 The Conjunctiva 177 Movements 87 The Cornea 178 Habitus and Body Proportions 88 The Red Eye 180 Is the Patient in Pain? 88 The Anterior Chamber 181 Is the Patient Dehydrated? 89 The Iris 184 Is the Patient Malnourished? 89 Pupils 184 Cleanliness and Grooming 89 Ophthalmoscopic Examination 189 Self-study: Speculation 89 Ophthalmoscopic Findings 193 References 89 APPENDIX 10.1 Answers to Questions on Pupillary Light Refl ex 220 6 The Vital Signs 90 APPENDIX 10.2 Answer to Question in Fig. 10-34 220 Blood Pressure 90 APPENDIX 10.3 Six Pearls of Clinical Ophthalmoscopy for the The Pulse 101 Primary Care Physician and Medical Consultant 220 Respiration 107 APPENDIX 10.4 Why Did House Staff Miss the Findings of Carotid Temperature 108 Occlusive Disease? 220 References 112 References 220 7 Integument 115 11 The Ear 224 Skin 115 External Inspection 224 Hair 138 Internal Inspection 226 Nails 141 Nonotologic Causes of Otalgia 228 APPENDIX 7.1 Answers to the Self-test in Fig. 7-1 146 Auscultation 228 APPENDIX 7.2 Answers to the Question in Fig. 7-4 146 Special Maneuvers 229 APPENDIX 7.3 Answer to Self-test on Café Au Lait Spots in APPENDIX 11.1 Earlobe Crease: Sensitivity, Specifi city, and Neurofi bromatosis 146 Predictive Value 234 APPENDIX 7.4 Answer to the Question in Fig. 7-6 and a Note APPENDIX 11.2 Testing the Diagnosis of a Blocked Eustachian on Terminology (Expressions of Ignorance) 146 Tube 234 APPENDIX 7.5 Predictive Value of Skin Tags for the Presence of APPENDIX 11.3 Answer to Question in Legend to Colonic Polyps 147 Figure 11-4 234 APPENDIX 7.6 Koilonychia in a Well-Baby Clinic 147 References 234 References 147 8 Lymph Nodes 151 12 The Nose 236 Dimensions 151 External Appearance 236 Lymph Node Groups 151 Internal Appearance 236 Evaluating the Clinical Signifi cance of Lymph Nodes 155 Special Maneuvers: Sense of Smell 240 APPENDIX 8.1 What is Wrong with the Story about Osler? 155 References 240 References 155 13 The Oropharynx 242 9 The Head 157 Order of Examination 242 Inspection 157 Oral Aperture 243 Palpation 162 Lips 243 Percussion 164 Tongue 244 Auscultation 164 Other Finding 245 Special Maneuvers: Transillumination 166 Teeth 245 A Note on Head and Facial Pain 166 Gums (Gingiva) 247 References 167 Palate 247 Buccal Mucosa 249 10 The Eye 168 Noma 251 Order of the Examination 168 Throat 251 Visual Acuity 168 Findings in Patients with Obstructive Sleep Apnea 252 Visual Fields 169 Larynx 253 The Lacrimal Apparatus 170 A Bouquet of Odors 253 The Eyelids and Other Periorbital Tissue 171 References 255 FFMM..iinndddd iivv 99//1199//22000099 11::0077::2255 PPMM Contents v 14 The Neck 258 Heart Failure? 363 Apparent Combination Lesions 363 Contour 258 Nonprecordial Murmurs 364 Deep Space Infections 258 A Comparison of Clinical Examination with Doppler Thyroid 258 Echocardiography 365 Parathyroid Glands 262 A Note on Cardiopulmonary Resuscitation 366 Trachea 262 More Advanced Imaging 366 Salivary Glands 263 APPENDIX 17.1 Massive Pericardial Effusion and the PMI 366 References 264 APPENDIX 17.2 Answer to Self-Study on Page 323 367 15 The Breast 266 APPENDIX 17.3 Why Laënnec Could Hear Better Than He Could Palpate 367 History: Risk Factors for Breast Cancer 266 APPENDIX 17.4 Key to Fig. 17-11 367 Draping the Female Patient 267 APPENDIX 17.5 Differential Diagnosis of a Murmur 367 Inspection 267 APPENDIX 17.6 Self-test on Mitral Valve Prolapse 367 Palpation 268 APPENDIX 17.7 CPC Diagnosis: A Case in Which a Murmur Similar Auscultation 270 to That of Mitral Stenosis Was Not Mitral Stenosis 367 Discharge from the Breast 270 APPENDIX 17.8 The Auenbrugger Sign 367 Gynecomastia 271 APPENDIX 17.9 When Is Congestive Heart Failure Not Congestive APPENDIX 15.1 Predictive Value of the Results of Screening Heart Failure? 367 Mammography 271 References 367 APPENDIX 15.2 Results of Testing Nipple Discharge for Occult Blood 272 18 Arteries 372 References 272 Carotid (and Vertebral) Arteries 372 16 The Chest 274 Temporal Arteries 382 Subclavian Artery 382 Inspection 274 Axillary and Brachial Arteries 383 Palpation 279 Wrist Arteries 383 Percussion 281 The Raynaud Phenomenon 384 Auscultation 289 Aorta 385 Special Maneuvers 299 Penile Artery 387 Synthesis 307 Renal Arteries and Other Causes of Abdominal Bruits 387 APPENDIX 16.1 Auscultatory Percussion for the Detection of Arteries of the Lower Extremities 390 Pleural Effusion 314 Pedagogic Inspiration 393 APPENDIX 16.2 Answer to the Self-test on the Specifi city of Microvasculature 393 Auscultatory Percussion, Page 304 314 Peripheral Perfusion and Shock 393 APPENDIX 16.3 Answers to Self-test on Diagnostic Findings, Other Vascular Conditions 393 Figs. 16-17–16-22. 314 APPENDIX 18.1 Answer to Question on Page 386 394 APPENDIX 16.4 Predictive Value of Diminished Breath Sounds for APPENDIX 18.2 Discussion of Case Report 394 the Detection of Moderate COPD 315 APPENDIX 18.3 Answer to Self-study on Page 389 394 References 315 References 394 17 The Heart 318 19 Veins 398 Inspection 318 Venous Pressure 398 Palpation 319 Jugular Venous Pulsations 406 Percussion 321 Auscultation 409 Auscultation 324 Venous Syndromes 410 Special Maneuvers 344 Synthesis 346 APPENDIX 19.1 The Circulation Time 413 Aortic Insuffi ciency 351 APPENDIX 19.2 Answer to Self-test on the Kussmaul Sign 414 Aortic Stenosis 351 APPENDIX 19.3 Diagnosticity of the Abdominojugular Refl ex 414 References 415 Mitral Insuffi ciency 354 Mitral Stenosis 357 20 The Abdomen 417 Pulmonic Insuffi ciency 359 Pulmonic Stenosis 359 Inspection 417 Tricuspid Insuffi ciency 360 Palpation 419 Tricuspid Stenosis 362 Percussion 423 Pericardial Effusion 362 Auscultation 423 When Is (Apparent) Congestive Heart Failure Not Congestive Special Maneuvers 424 FFMM..iinndddd vv 99//1199//22000099 11::0077::2255 PPMM vi Contents Synthesis 425 The Appendicular Skeleton: Joints and Associated Parts 504 APPENDIX 20.1 Differential Diagnosis of the Patient in Peripheral Nerve Injuries and Entrapment Neuropathies 515 Fig. 20-5 437 APPENDIX 25.1 Myopathy: Answer to Question (in an Exercise APPENDIX 20.2 Which Side Has the Perinephric Abscess? 437 for the Student) 523 APPENDIX 20.3 Answer to Self-study on Differential APPENDIX 25.2 Answer to Question in Figure 25-2 Legend 523 Diagnosis 437 References 523 References 437 26 The Neurologic Examination 526 21 Male Genitalia 440 Overview 526 Penis 440 Cranial Nerves 527 Scrotum 443 Skilled Acts 544 Testes, Epididymis, and Spermatic Cords 445 Meningitis 547 Hernias 447 Posture 548 Prostate and Seminal Vesicles 448 Movement Disorders 551 References 448 Coordination 556 Motor Examination 563 22 Female Genitalia 449 Refl exes 569 Overview 449 Sensory Testing 579 External Genitalia 451 Autonomic Nervous System 588 Vaginal Examination 456 Intracranial Lesions 588 Bimanual Examination 460 Selected Neurologic Symptoms or Diagnoses 591 Synthesis 463 Consciousness, Stupor, and Coma 596 References 463 Cognition 600 Functional Imaging in Encephalopathy 612 23 The Rectum 465 A Coda on the Patient with a Chronic Neurologic Illness 612 APPENDIX 26.1 Answer to Self-study Question on the Red Glass Preparing the Student 465 Test 612 Preparing the Patient for Examination 465 APPENDIX 26.2 Self-test on the Corneal Refl ex 612 Examination 466 APPENDIX 26.3 Why Parkinson Could Not Detect Findings 466 Cogwheeling 612 Alleged Adverse Effects of the Rectal Examination 468 APPENDIX 26.4 Delusions 612 Special Maneuver: Anoscopy 469 APPENDIX 26.5 Assessment of Affect 613 Screening for Colorectal Cancer 469 APPENDIX 26.6 Hysteria 613 APPENDIX 23.1 Answer to Self-study (Signs of Sexual Abuse) 469 APPENDIX 26.7 The Brief MAST (Pokorny et al., 1972) 613 APPENDIX 23.2 Answer to Self-study (Prostatic Nodules) 469 References 613 References 469 27 Clinical Reasoning 620 24 The Extremities 471 Principles of Clinical Reasoning 620 Upper Extremities 471 Differential Diagnosis 624 Lower Extremities 481 APPENDIX 27.1 Analysis for the Problem in Logical Fallacies APPENDIX 24-1. Answer to Self-study (Nodules in Rheumatoid Section 632 Arthritis and Rheumatic Fever) 486 APPENDIX 27.2 A Method for Solving the Problem in Diagnosis by APPENDIX 24.2 Answer to Question in Fig. 24-2 Legend 486 Exclusion Section 632 APPENDIX 24.3 Answer to Question in Fig. 24-8 Legend 486 References 632 APPENDIX 24.4 Answer to Question in Fig. 24-9 Legend 486 APPENDIX 24.5 A Note on the Pit Recovery Time: Answers to 28 Some Bedside Laboratory Tricks 633 Questions in Fig. 24-13 486 Blood 633 References 486 Urine 640 25 The Musculoskeletal System 488 Other Body Fluids and Secretions 645 The Future of Diagnostic Testing 648 Muscle Disorders 488 References 649 Bone 491 The Tensegrity Model 493 29 Annotated Bibliography 651 Basic Principles of Examination 493 Index 654 The Axial Skeleton 497 FFMM..iinndddd vvii 99//1199//22000099 11::0077::2266 PPMM P F R E F A C E T O T H E O U R T H E D I T I O N From the day when the fi rst members of councils placed exterior behavior of patients and physicians, there remains the problem that authority higher than interior, that is to say, recognized the human beings are not stamped from an industrial die. Even if not totally unique in genetic endowment, each human being has had a decisions of men united in councils as more important and more different interaction with the world. sacred than reason and conscience; on that day began lies that As the art of medicine is being lost, the science is also threatened. caused the loss of millions of human beings and which continue “Evidence-based” medicine is coming to mean based on the consensus their unhappy work to the present day. of a committee of experts: the Prussian Geheim Rath with many heads —LEO TOLSTOY (and no heart). Clinical reasoning is replaced by following a prac- tice “guideline” from one prescribed information bit to another, and a Since the fi rst edition went to press, the revolution has pro- diagnosis means a number with fi ve signifi cant digits (never mind that ceeded apace. At hospital committee meetings these days, the dis- the fi rst one is dubious) attached to an appropriate procedure code. connection between medicine as once taught by prerevolutionary The very altar of truth—the autopsy table—is being dismantled. physicians and medicine as now codifi ed by compliance-minded, It is telling that bureaucratic quality assessment is almost always MBA-qualifi ed “medical directors” is startling; the author feels as based on process (read compliance) measures such as number of though she arrived at such meetings by time machine. blood pressure determinations or prescriptions for the medica- In the new “integrated delivery systems,” the organizational tion du jour, not outcome measures such as all-cause mortality or chart reigns. Physicians are boxed into defi ned categories, next to ability to function independently. Regardless of the reading on the the bottom of the chart, just above the patients; together with the “continuous quality improvement” dashboard, almost everyone on patients (now known as “covered lives”), they form the “medical the front lines of patient care believes that American medicine and loss ratio.” health are in decline. It is a world of paradox. Talk of “ethics” generally means talk of Why, then, another edition of this book? “resource allocation,” often by means once called unethical. One Medicine is a living thing that will survive and fl ourish, despite drowns in information, but the key of knowledge is lost. Facilities the dinosaurs of “health care delivery,” and long after inhuman sys- and personnel are present in excess, and yet they are scarce. tems fail. There are still students who aspire to be physicians, not The scarcest item of all appears to be the clinician’s time. Thirty providers, gatekeepers, resource managers, or box-checkers. There seconds may be too long to spend searching for a reference. In some are still those who consider medicine to be a human and a humane settings, there may be no time to look in the left ear if only the right endeavor, not an industry. This book is to provide them a compass, one hurts, much less to listen to the patient’s grief or despair. And a road map, and, perhaps, a little entertainment as they embark on when can today’s managed provider stop and refl ect? an exciting journey of exploration, together with their most impor- Concepts are imported from industry, such as “six sigma tant teachers: their patients. quality”—the goal to reduce errors below 6 standard deviations As students begin their foray into physical diagnosis, frequently from the mean of a normal distribution. This means that all but 3.4 feeling overwhelmed by the vast amount of data they must absorb, out of 1 million patients are supposed to meet a certain indicator, the most helpful piece of advice might be that offered in 1957 by such as timely Pap smears or mammograms, regardless of individ- neurologist Robert Wartenberg: “Mistakes in neurologic diagnosis ual needs and desires. are more likely to result from not looking enough than from not Quality experts in industry do recognize that one cannot con- knowing enough.” trol outputs without controlling inputs—a fact that health policy experts seldom acknowledge. But even if we could control the —Jane M. Orient, M.D., 2009 vii FFMM..iinndddd vviiii 99//1199//22000099 11::0077::2266 PPMM P F R E F A C E T O T H E I R S T E D I T I O N As the decay of the Chou Dynasty grew worse, studies were neglected 19th century translator of Galen, who believed that medicine could and the scribes became more and more ignorant. When they did be greatly improved only if the ignorant physicians of his day had access to Galen’s work. After devoting his life to translating Galen not remember the genuine character, they blunderingly invented a into modern languages, he found that his task had immediately false one. These non-genuine characters, copied out again by other become an exercise in obsolescence, due to the beginning of the ignorant writers, became usual. scientifi c era of medicine. Yet, one daily observes patients for whom —L. WIEGER, SJ, CHINESE CHARACTERS the history and physical examination could lead one to the correct diagnosis hours, days, and even weeks before it can be achieved by The goal of this book is to help the reader achieve the correct those who rely solely on modern technology. And for some diagno- personal, metaphysical, and epistemologic perspectives on the artful ses (e.g., vascular headache, depression, irritable colon), there is no science of clinical examination. This is not a textbook of medicine. substitutive technology. In analogy to football, a textbook of medicine is the playbook. This Plowing through this tome, learning what you can, and noting book is about learning the skills of blocking, tackling, punting, pass- other passages for future use is hopefully part of your initiation into ing, and so forth, so that one may execute the plays with diligence a very special and elite club. This club collects no dues and has no and facility. scheduled meetings (although you can attend a meeting any time The style is intentionally unusual, attempting to capture the you wish by picking up a book). It is founded on a certain value excitement of actual rounds with diversions along the way. This hierarchy, irrespective of dramatic changes in technology, and exists should help to hold the attention of today’s students and residents, in the dimension of time, mostly irrespective of place. who are often caught up in pointless memorizing and unproduc- The tradition of clinical examination dates back 2,500 years tive errand-running at the expense of scholastic preparation for the or earlier. The author of this book, who is attempting to help lifelong task of self-teaching. train you, was trained by Dr Jack Myers, who was trained by This book is written with a sense of great sadness about American Dr Soma Weiss. With suffi cient scholarly effort, it would be pos- academic medicine and from a prerevolutionary point of view (the sible to trace a lineage from any reader back to Laënnec or even revolution in academic medicine having occurred about 1968,1 to Hippocrates. when the intellectual approach to diagnosis and its attendant tech- We owe a great debt to those who taught us. The only way to niques of clinical examination fell into disrespect, superseded by an repay the debt is to transmit the knowledge to the next generation, inappropriately exclusive reliance on dogma and modern techno- insofar as it is possible. In every hospital and every school that I logic devices). If the current civilization preserves even more trivial visit, I meet young persons of the prerevolutionary type. This book records of its behavior than did the Sumerian culture, then the pres- is for them. ent text may be of interest to historians of future ages. Some may think that this book will be held in the same regard as the work of a —Joseph D. Sapira, M.D., 1989 1 Chargaff, working independently from completely different observa- tions, also selects 1968 as the year of revolution. (See Chargaff E. H eraclitean Fire: Sketches from a Life Before Nature. New York: Rockefeller University Press; 1978.) viii FFMM..iinndddd vviiiiii 99//1199//22000099 11::0077::2266 PPMM A C K N O W L E D G M E N T S I cannot begin to thank all those who helped me learn c linical For the third edition, I am indebted to many more, including medicine. I still sometimes feel as though Dr Albert Grokoest, my Dr Ashish Goel for a highly perceptive overall review and many use- physical diagnosis instructor at Columbia College of Physicians ful comments; Dr Chester Danehower for his critique of Chapter 7 and Surgeons, is looking over my shoulder, admonishing me to pay and additional illustrations; Drs Michael A. J. Robb and Laurence attention to the patient and not just the technical details. Dr George Marsteller for insights into tinnitus and otoneurologic problems; Dr Wales King, Tucson family physician, let me follow him around for a Curtis Caine for pearls on airway management; Dr Del Meyer for whole summer, teaching me something of the meaning of physician- reviewing Chapter 16; Dr Brendan Phibbs for critiquing C hapter 17 hood. Dr Marianne Legato provided exemplary bedside teaching and offering many clinical pearls; Dr Stuart Danovitch for contrib- at Roosevelt Hospital in the City of New York. Dr Donald Seldin, uting to Chapters 20 and 23; Dr A. Lee Dellon for the discussions Chairman of the Department of Medicine at Texas Southwestern, of peripheral nerve injuries and sensory testing; Dr Rene Allen for taught me that even the Professor needs to go to the bedside and reviewing Chapter 22; Dr Richard Neubauer for information on examine the patient fi rsthand. Dr Rubin Bressler, Chairman of the hyperbaric oxygenation; Dr Philip James for invaluable insights into Department of Medicine at the University of Arizona, taught me multiple sclerosis; Drs Sam Paplanus and Ron Spark for reviewing that the most important thing was not the adherence to the pro- Chapter 28; and countless others. Drs Gervais and Huntoon once tocol of the moment but the answer to the question: “How is the again gave hours of their time for updating and correcting Chapters patient doing?” 10 and 26. I am deeply indebted to Dr Sapira for inviting me to help with For the fourth edition, I am also grateful to Dr Alan Rapoport the fi rst edition of this book. for insights into likelihood ratios and into the differential diagnosis Many busy practicing physicians gave generously of their time of apparent “lymph nodes” and for pointing out several errors in to review parts of this book and to contribute additional mate- the text; Dr F. Edward Yazbak for reviewing portions of the text rial. Those who helped with the second edition include Drs Joseph concerned with pediatrics; Dr Timothy Fagan for helpful correc- Scherzer, Don Printz, and Claud Boyd, Jr (Chapter 7); Drs Michael tions and suggestions to Chapter 6; Dr Tamzin Rosenwasser for Schlitt and Miguel Faria (Chapters 9 and 26); Dr Robert Gervais help with Chapter 7 and questions on the integument; Dr Angela (Chapter 10); Drs Vernon L. Goltry and John H. Boyles, Jr Lanfranchi for many contributions to the discussion of the breast ( Chapters 11 to 14); Dr Jerome Arnett (Chapter 16); Drs Eddie examination; Dr Jerome Arnett for many useful additions and cor- Atwood and Rachel Marcus (Chapter 17); Dr W. Daniel J ordan rections to Chapter 16; Dr Karen Smith for making me aware of (Chapters 18 and 19); Dr Sheldon Marks (Chapter 21); Drs Devra the importance of cervical spine disease in rheumatoid arthritis; Marcus and Sara Imershein (Chapter 22); Dr James Klein (Chapter 23); Dr Edward Harshman for a method for determining the level of Drs Thomas Dorman and John Dwyer (Chapters 24 and 25); and spinal cord injury by checking intercostal muscle function; and Dr Lawrence Huntoon (Chapter 26). I thank Drs Joseph Scherzer, Dr John Minarcik for reviewing Chapter 28. Michael Schlitt, and Devra Marcus for contributing photographs, Research for this book was made possible by the assistance and Dr Huntoon for contributing drawings. Dr William Summers of Marcia Arsenault (second edition) and Michelle Bureau (third added to the discussion of dementia in Chapter 26. Dr D.R. Royall and fourth editions), Librarians Extraordinaire, of Carondelet St provided the executive interview in Chapter 26. Raquel Pérez, Joseph’s Hospital in Tucson, Arizona, and to Carondelet St Joseph’s R.N., helped with the revision of the Spanish–English database. Drs for the use of its library resources. Milne J. Ongley and Thomas Dorman instructed me in examination I also thank Jeremy Snavely for computer consultation; my techniques used in orthopedic medicine, and Dr Dorman granted s ister Ruth Stensrud and my mother Phyllis Orient for tolerance, unstinting permission to reprint illustrations from Diagnosis and assistance in innumerable practical ways, and proofreading; Emily Injection Techniques in Orthopedic Medicine by Thomas A. Dorman and Snavely for clerical assistance and proofreading; and Patti Wylie for Thomas H. Ravin, Williams and Wilkins, Baltimore, 1991. numerous photographs. ix FFMM..iinndddd iixx 99//1199//22000099 11::0077::2266 PPMM FFMM..iinndddd xx 99//1199//22000099 11::0077::2266 PPMM

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The Fourth Edition of this textbook teaches the artful science of the patient interview and the physical examination—from the fundamentals to the most advanced levels. Written in an artful storytelling style, the book describes methods in step-by-step detail, with clinical pearls, vignettes, pract
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