Santhosh K Gouroji Anes Fr Muller 2013

83 Pages·2012·2.39 MB·English

A COMPARATIVE STUDY OF 2% LIDOCAINE PLUS 0.5%
ROPIVACAINE VERSUS 2% LIDOCAINE PLUS 0.5%
BUPIVACAINE FOR PERIBULBAR ANESTHESIA IN
CATARACT SURGERIES

by

Dr. SANTHOSH K.GOUROJI

Dissertation Submitted to the
Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore

In partial fulfillment
of the requirements for the degree of

M.D.
in
Anesthesiology

Under the guidance of

DR. KISHAN SHETTY, M.D.
Associate Professor

Department of Anesthesiology
&
Dr. NORMAN MENDONCA, M.S.
Professor and Head,
Department of Ophthalmology
Father Muller Medical College
Kankanady, Mangalore

2013
i
Rajiv Gandhi University of Health Sciences
Bangalore, Karnataka

Declaration by the Candidate

I hereby declare that this dissertation/thesis entitled “A COMPARATIVE
STUDY OF 2% LIDOCAINE PLUS 0.5% ROPIVACAINE VERSUS 2%
LIDOCAINE PLUS 0.5% BUPIVACAINE FOR PERIBULBAR ANESTHESIA
IN CATARACT SURGERIES" is a bonafide and genuine research work carried
out by me under the guidance of Dr. KISHAN SHETTY M.D. Associate Professor,
Department of Anesthesiology, Father Muller Medical College, Mangalore.

D ate :
Dr. SANTHOSH K.GOUROJI

Place: Mangalore

ii
Certificate by the Guide

This is to certify that the dissertation entitled “A COMPARATIVE STUDY
OF 2% LIDOCAINE PLUS 0.5% ROPIVACAINE VERSUS 2% LIDOCAINE
PLUS 0.5% BUPIVACAINE FOR PERIBULBAR ANESTHESIA IN
CATARACT SURGERIES" is a bonafide research work done by
Dr.SANTHOSH K. GOUROJI in partial fulfillment of the requirement for the
degree of M.D.(Anesthesiology)

Date :
Dr. KISHAN SHETTY M.D
Place: Mangalore
Associate Professor

Department of Anesthesiology

Father Muller Medical College

Kankanady, Mangalore

iii
Certificate by the Co- Guide

This is to certify that the dissertation entitled “A COMPARATIVE STUDY
OF 2% LIDOCAINE PLUS 0.5% ROPIVACAINE VERSUS 2% LIDOCAINE
PLUS 0.5% BUPIVACAINE FOR PERIBULBAR ANESTHESIA IN
CATARACT SURGERIES" is a bonafide research work done by
Dr.SANTHOSH K. GOUROJI in partial fulfillment of the requirement for the
degree of M.D.(Anesthesiology)

Date :
Dr. NORMAN MENDONCA M.S
Place: Mangalore
Professor and Head

Department of Ophthalmology

Father Muller Medical College

Kankanady, Mangalore

iv
Endorsement by the HOD, Principal/
Head of the Institution

This is to certify that the dissertation entitled “A COMPARATIVE STUDY
OF 2% LIDOCAINE PLUS 0.5% ROPIVACAINE VERSUS 2% LIDOCAINE
PLUS 0.5% BUPIVACAINE FOR PERIBULBAR ANESTHESIA IN
CATARACT SURGERIES" is a bonfire research work done by Dr.SANTHOSH
K.GOUROJI under the guidance of Dr. KISHAN SHETTY M.D. Associate
Professor, Department of Anesthesiology, Father Muller Medical College, Mangalore.

Dr. MAHABALA.T.H M.D Dr. JAYAPRAKASH ALVA M.D.
Professor and Head, Dean

Department of Anesthesiology Father Muller Medical College
Father Muller Medical College Mangalore- 575002
Kankanady, Mangalore 575002

Date : Date :
Place: Mangalore Place: Mangalore
v
COPYRIGHT

Declaration by the Candidate

I hereby declare that the Rajiv Gandhi University of Health Sciences,
Karnataka shall have the rights to preserve, use and disseminate this dissertation /
thesis in print or electronic format for academic / research purpose.

Date:

P lace: Mangalore Dr. SANTHOSH K. GOUROJI

© Rajiv Gandhi University of Health Sciences, Karnataka

vi
Acknowledgment

I thank GOD for his blessings bestowed on me, without which I would
not be able to complete this task.
I owe a great sense of indebtedness to Dr. MAHABALA. T.H., MD.,
Professor and Head, Department of Anesthesiology, Father Muller Medical
College, Mangalore, who has been an excellent teacher, inculcating in me the
importance of hard work, dedication and commitment during my course.
I would like to express my deep sense of gratitude towards my guide
Dr. KISHAN SHETTY,M.D., Associate Professor, Department of Anesthesiology,
who was the guiding force behind my dissertation. His initiative, motivation and
constant support helped me to complete this study.
I am especially indebted to Dr. NORMAN MENDONCA,M.S., D.O.M.S.,
Professor and Head, Department of Ophthalmology for all the support he has lent
towards my thesis completion.
I extend my immense gratitude to my teachers, Dr. SUDHIR HEGDE,
M.D., Dr.RADHESH HEGDE,M.D., DR.PRITHI JAIN,D.N.B,D.A., and
Dr. GURUMURTHY, M.D., for their practical guidance and valuable teaching
throughout the course.
I thank DR. LULU SHERIF,M.D., who provided valuable inputs and
encouraged me at every stage in the conduct of this study.
I am extremely thankful to my teachers Dr.SHAILAJA,D.N.B.,D.A.,
Dr.HARSHAVARDHAN, M.D., Dr.KARL SA RIBIERO, M.D., who helped me
acquire adequate skills and knowledge during this course.
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I also thank the Medical Superintendent and OT Staff of our hospital
for their cooperation and assistance.
I would also like to thank Mrs. Sucharita Suresh, who guided me with
the statistics.
I take this opportunity to thank Mrs. Gayathri Hegde and her staff at
Microbits for their outstanding work in printing this manuscript.
My heartfelt thanks to each and every patient who agreed to be a part
of this study. I also apologise my patients for any inconvenience during the
study.
I am grateful to my parents, my sister Mrs. Sarala A. T. and family
members for their encouragement in every step and support in every hurdle of
my life.
Last but not the least, I would like to thank all my friends and
colleagues in the department of anesthesiology without whose help and
cooperation it would not have been possible to complete this work.

Date :
Place: Mangalore Dr. SANTHOSH K. GOUROJI

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LIST OF ABBREVIATIONS USED

 - Alpha
Β - Beta
Γ - Gamma
ANOVA - Analysis of Variance
ASA - American Society of Anesthesiologist
bpm - Beats per minute
cc - Cubic centimeter
cm - Centimeter
CNS - Central Nervous System
CVS - Cardiovascular System
ECG - Electrocardiogram
g - Grams
hrs - Hours
IOP - Intraocular Pressure
IU - International Units
IV - Intravenous
kg - kilograms
L - Liter
MAP - Mean Arterial Pressure
mcg - microgram
mg - milligram
min - minutes
ml - milliliter
mm - millimeter
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mm Hg - millimeter of mercury
pKa - Acid Dissociation Constant
PPX - Pipecoloxylidide
Vmax - Maximum Velocity
Yr - Year
x