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Samuel’s Manual of Neurologic Therapeutics PDF

1218 Pages·2017·4.4 MB·English
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SAMUELS’S MANUAL OF NEUROLOGIC THERAPEUTICS Ninth Edition EDITORS Martin A. Samuels, MD, DSc (hon), FAAN, MACP, FRCP, FANA Chairman Department of Neurology Brigham and Women’s Hospital Miriam Sydney Joseph Professor of Neurology Harvard Medical School Boston, Massachusetts Allan H. Ropper, MD, FACP, FAAN Executive Vice-Chairman Department of Neurology Brigham and Women’s Hospital Professor of Neurology Harvard Medical School Boston, Massachusetts Executive Editor: Rebecca Gaertner Acquisitions Editor: Chris Teja Editorial Coordinator: Emily Buccieri Strategic Marketing Manager: Rachel Mante Leung Production Project Manager: David Orzechowski Design Coordinator: Joan Wendt Manufacturing Coordinator: Beth Welsh Prepress Vendor: Absolute Service, Inc. Ninth edition Copyright © 2017 Wolters Kluwer. © 2010 by LIPPINCOTT WILLIAMS & WILKINS, a WOLTERS KLUWER business. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at [email protected], or via our website at lww.com (products and services). 9 8 7 6 5 4 3 2 1 Printed in China Library of Congress Cataloging-in-Publication Data Names: Samuels, Martin A., editor. | Ropper, Allan H., editor. Title: Samuels’s manual of neurologic therapeutics / editors, Martin A. Samuels, Allan H. Ropper. Description: Ninth edition. | Philadelphia : Wolters Kluwer Health, [2017] | Includes bibliographical references and indexes. Identifiers: LCCN 2016056638 | eISBN 9781496360342 Subjects: | MESH: Nervous System Diseases—diagnosis | Nervous System Diseases—therapy | Outlines Classification: LCC RC349.8 | NLM WL 18.2 | DDC 616.8/046—dc23 LC record available at https://lccn.loc.gov/2016056638 This work is provided “as is,” and the publisher disclaims any and all warranties, express or implied, including any warranties as to accuracy, comprehensiveness, or currency of the content of this work. This work is no substitute for individual patient assessment based upon healthcare professionals’ examination of each patient and consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data, and other factors unique to the patient. The publisher does not provide medical advice or guidance, and this work is merely a reference tool. Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for any resulting diagnosis and treatments. Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and treatment options should be made, and healthcare professionals should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information sheet (the manufacturer’s package insert) accompanying each drug to verify, among other things, conditions of use, warnings, and side effects and identify any changes in dosage schedule or contraindications, particularly if the medication to be administered is new, infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or otherwise, or from any reference to or use by any person of this work. LWW.com Dedication This edition of Samuels’s Manual of Neurologic Therapeutics is dedicated to H. Richard Tyler who died during the preparation of this book. Rick was a brilliant neurologist, teacher, and bibliophile, who preceded one of us (MAS) as the Chief of Neurology at the Brigham. He arrived at the then Peter Bent Brigham Hospital in 1951 as an intern, having received his medical degree from Washington University. He then trained in neurology at the Boston City Hospital. After stints at the National Hospital for Neurology and Neurosurgery in London and the Salpêtrière Hospital in Paris, he was recruited back to the Brigham to become the first full-time neurologist and then in the Department of Medicine. During his 32-year tenure in that leadership role, neurology was greatly expanded. Through merger with the Boston Hospital for Women and the Robert Breck Brigham Hospital, the institution became the Brigham and Women’s Hospital in 1975 in which Rick led neurology until he stepped down in 1988. After leaving the leadership position in Brigham Neurology, he continued to practice full-time, right up until his sudden death in 2016. As the lone neurologist in a general hospital, Rick Tyler focused on the neurologic aspects of medical and surgical diseases, particularly those in which the Brigham was a leading institution. He characterized the physiologic nature of asterixis and tremor, the typical movement disorders seen in patients with metabolic encephalopathies. The Brigham was the site of the first renal transplantation, so Rick became the reigning expert on the neurologic manifestation of chronic kidney disease, including renal replacement therapy, dialysis, and transplantation. He was expert in the neurologic manifestation of alcoholism and malnutrition, including vitamin and mineral deficiency syndromes. He also articulated the most important neurologic aspects of congenital heart disease in adults. Rick Tyler was a serious medical historian and collector of rare books. His extraordinary collection was donated to the American Academy of Neurology where it is curated and displayed at his medical alma mater, Washington University in St. Louis. Residents and students from several generations were treated to his dissertations on important landmarks in neurologic history, illustrated by one or more of his rare books. The library in the Department of Neurology at the Brigham is dedicated to Rick and serves as the epicenter of all of the academic activities of the department. Harvard medical students from several eras all remember his compelling lectures on neurology, which emphasized his dedication to a careful neurologic history and examination. His patients adored and respected him, realizing that he would always be there to help them with their suffering—always willing to listen and to offer new ideas for relief. To him, medicine was a calling, not just an occupation. He worked days, nights, weekends, and holidays. Rick Tyler represented a brand of personalized medicine that we can only hope to emulate in the modern era. Despite his dedication to work, he demonstrated a deep commitment to his family, his wife and children, many of whom paid him the greatest compliment by becoming distinguished physicians and surgeons in their own rights. The editors and authors, almost all of whom are now working in the Department of Neurology at the Brigham, are delighted and honored to dedicate this ninth edition of Samuels’s Manual of Neurologic Therapeutics to one of great treating neurologists, H. Richard Tyler. Martin A. Samuels Allan H. Ropper Cover design adapted with permission from Leavitt S, Tyler HR. Studies in asterixis, part I. Arch Neurol. 1964;10(4):360–368. Figure 9, page 366. Copyright © (1964) American Medical Association. All rights reserved. Association of asterixis with an absolute silent period, synchronous in three muscle groups. Contents Contributing Authors Foreword by Thomas Sabin Preface Preface to the First Edition 1 Coma, Head Trauma, and Spinal Cord Injury Galen V. Henderson and Matthew B. Bevers 2 Epilepsy Rani A. Sarkis and Barbara Dworetzky 3 Dizziness Gregory T. Whitman and Robert W. Baloh 4 Back and Neck Pain Allan H. Ropper 5 Sleep Disorders Milena Pavlova 6 Cancer Neurology Eudocia Quant Lee and Patrick Y. Wen 7 Multiple Sclerosis and Related Disorders Maria K. Houtchens and James M. Stankiewicz 8 Autoimmune Disorders Ivana Vodopivec and Henrikas Vaitkevicius 9 Neuromuscular Junction Disorders and Myopathies Anthony A. Amato and Mohammad Kian Salajegheh 10 Motor Neuropathies and Peripheral Neuropathies Mohammad Kian Salajegheh and Anthony A. Amato 11 Chronic Pain Daniel D. Vardeh 12 Headache and Facial Pain Paul B. Rizzoli and Elizabeth Loder 13 Stroke and Cerebrovascular Disorders Henrikas Vaitkevicius and Steven K. Feske 14 Movement Disorders Jordan D. Paulson and Lewis R. Sudarsky 15 Behavioral and Cognitive Neurology Seth A. Gale and Kirk Daffner 16 Management of Neurologic Disorders in Resourc e-Limited Settings Aaron L. Berkowitz 17 Neuroophthalmology Robert M. Mallery and Sashank Prasad 18 Toxic and Metabolic Disorders Shamik Bhattacharyya and Martin A. Samuels 19 Infectious Diseases Jennifer Lyons and Tracey A. Cho Drug Index Subject Index Contributing Authors Anthony A. Amato, MD Chief, Division of Neuromuscular Diseases Department of Neurology Brigham and Women’s Hospital Professor of Neurology Harvard Medical School Boston, Massachusetts Robert W. Baloh, MD Director, Neuro-otology Clinic and Laboratory Ronald Reagan Medical Center Professor of Neurology and Head and Neck Surgery David Geffen School of Medicine at UCLA Los Angeles, California Aaron L. Berkowitz, MD, PhD Director, Global Neurology Program Department of Neurology Brigham and Women’s Hospital Assistant Professor of Neurology Harvard Medical School Boston, Massachusetts Matthew B. Bevers, MD, PhD Neurointensivist, Division of Critical Care Neurology Brigham and Women’s Hospital Instructor in Neurology Harvard Medical School Boston, Massachusetts Shamik Bhattacharyya, MD, MS Associate Neurologist Brigham and Women’s Hospital

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Hands-on guidance on treating neurologic disease. The best-selling Samuels’s Manual of Neurologic Therapeutics is a practical, accessible handbook for the diagnosis and treatment of neurologic disorders. Completely updated to reflect the most recent developments in the field, the book features a c
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Most books are stored in the elastic cloud where traffic is expensive. For this reason, we have a limit on daily download.