Role of Oxidative Stress in Pathophysiology of Diseases

302 Pages·2020·6.248 MB·English

by  Pawan K. Maurya, Kamal Dua

Pawan K. Maurya
Kamal Dua  Editors
Role of Oxidative
Stress in
Pathophysiology
of Diseases
Role of Oxidative Stress in Pathophysiology
of Diseases
(cid:129)
Pawan K. Maurya Kamal Dua
Editors
Role of Oxidative Stress in
Pathophysiology of
Diseases
Editors
PawanK.Maurya KamalDua
DepartmentofBiochemistry DisciplineofPharmacy,GraduateSchool
CentralUniversityofHaryana ofHealth
Mahendergarh,Haryana,India UniversityofTechnologySydney
Sydney,NSW,Australia
ISBN978-981-15-1567-5 ISBN978-981-15-1568-2 (eBook)
https://doi.org/10.1007/978-981-15-1568-2
#SpringerNatureSingaporePteLtd.2020
Thisworkissubjecttocopyright.AllrightsarereservedbythePublisher,whetherthewholeorpartofthe
materialisconcerned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,
broadcasting,reproductiononmicrofilmsorinanyotherphysicalway,andtransmissionorinformation
storageandretrieval,electronicadaptation,computersoftware,orbysimilarordissimilarmethodology
nowknownorhereafterdeveloped.
Theuseofgeneraldescriptivenames,registerednames,trademarks,servicemarks,etc.inthispublication
doesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevant
protectivelawsandregulationsandthereforefreeforgeneraluse.
The publisher, the authors, and the editorsare safeto assume that the adviceand informationin this
bookarebelievedtobetrueandaccurateatthedateofpublication.Neitherthepublishernortheauthorsor
theeditorsgiveawarranty,expressedorimplied,withrespecttothematerialcontainedhereinorforany
errorsoromissionsthatmayhavebeenmade.Thepublisherremainsneutralwithregardtojurisdictional
claimsinpublishedmapsandinstitutionalaffiliations.
ThisSpringerimprintispublishedbytheregisteredcompanySpringerNatureSingaporePteLtd.
The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721,
Singapore
The publication of this book was finalised
during the Coronavirus (COVID-19)
pandemic.Wewouldliketodedicatethisbook
to all those who were affected by the
pandemic, and in particular, to our health
workforce around the world for their
dedication and care during this difficult time
Contents
1 OxidativeStressandOralDiseases. . . . . . . . . . . . . . . . . . . . . . . . . 1
AravindKumarSubramanian,VivekNarayan,andR.Navaneethan
2 TheRoleofOxidativeStressinChronicLiverDiseases. . . . . . . . . 13
DevarajEzhilarasan,ShanmugamRajeshkumar,
andThangaveluLakshmi
3 TheRoleofDiverseNanoparticlesinOxidativeStress:
InVitroandInVivoStudies. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
ShanmugamRajeshkumar,DurairajSekar,DevarajEzhilarasan,
andThangaveluLakshmi
4 OxidativeStressinNeurologyandinNeurodegenerative
Processes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
GauravGupta,SacchidanandPathak,SaritaRawat,AnuragMishra,
YogendraSingh,MeenuMehta,SaurabhSatija,NavneetKhurana,
TerezinhadeJesusAndreoliPinto,ShaktiShukla,KavitaPabreja,
andDineshKumarChellappan
5 RoleofOxidativeStressinComplexityofRespiratoryDiseases. . . 67
MalihehGhadiri,AmandaEugeniaYung,andMehraHaghi
6 TheRoleofSynbioticsinAlleviatingOxidativeStress
inColorectalCancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
MonicaGulati,SachinKumarSingh,andApoorvaSingh
7 OxidativeStressandImmunologicalComplexities
inMultidrug-ResistantTuberculosis. . . . . . . . . . . . . . . . . . . . . . . . 107
RidhimaWadhwa,NikitaSehgal,NareshG,TaruAggarwal,
SaurabhSatija,MeenuMehta,GauravGupta,DineshK.Chellappan,
MurtazaM.Tambuwala,BrainOliver,TrudiCollet,
PawanK.Maurya,PhilipM.Hansbro,andKamalDua
vviiii
viii Contents
8 Infection-InducedOxidativeStressinChronicRespiratory
Diseases. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125
ShaktiD.Shukla,KanthSwaroopVanka,AnneChevalier,
WaiChingChong,KavitaPabreja,MadhurD.Shastri,
andRonanF.O’Toole
9 OxidativeStressinDepressionandOtherComorbidDisorders. . . 149
ShvetankBhatt,DilipKumarPandey,ChandragoudaR.Patil,
andA.N.Nagappa
10 OxidativeStressMonitoringinInVitroandInVivoModels. . . . . 163
ThaniaRiosRossiLima,BiancaCamargoPenteadoSales,
andLilianCristinaPereira
11 EffectsofYogaonOxidativeStressDuringAging. . . . . . . . . . . . . . 179
RiyaGuptaandPawanK.Maurya
12 MolecularLevelInsightintotheInvolvementofHeatShock
ProteinsinOxidative-Stress-MediatedHumanDiseases. . . . . . . . . 195
SangeetaMitra,AngshumanBagchi,andRakhiDasgupta
13 OxidativeStressinLiverDiseases. . . . . . . . . . . . . . . . . . . . . . . . . . 209
LubhanSingh,SagarikaMajhi,KavitaPabreja,PoonamNegi,
RohitGoyal,GauravGupta,DineshKumarChellappan,
andKamalDua
14 OxidativeStressandInflammationCanFuelCancer. . . . . . . . . . . 229
ForamU.Vaidya,AbuSufiyanChhipa,NibhaSagar,
andChandramaniPathak
15 RoleofOxidativeStressinChronicKidneyDisease. . . . . . . . . . . . 259
KiranDahiya,RakeshDhankhar,PriyaDahiya,RaunakAhlawat,
andNavdeepHooda
16 RoleofOxidativeStressinthePathophysiology
ofType2DiabetesandCardiovascularDiseases. . . . . . . . . . . . . . . 277
OlorunfemiR.Molehin,StephenA.Adefegha,
andAnneA.Adeyanju
About the Editors
Pawan K. Maurya is currently an Associate Professor at the Department of
Biochemistry, Central University of Haryana. He is also Deputy Director of Deen
DayalUpadhyayKaushalKendra(DDUKK)atthesameuniversity.HeholdsaPh.
D. from the University of Allahabad and pursued research work as a Postdoctoral
researcheratTaipeiMedicalUniversity,TaiwanandtheFederalUniversityofSao
Paulo(UNIFESP),Brazil.Hisresearchfocusesonoxidativestress,aging,telomere
biology, biochemical diagnostics, nanomedicine, and clinical biochemistry.
Dr. Maurya hasreceived severalnationalandinternationalawardssuchasScience
without Borders, Brazil (2014), and a Distinguished Service Award, Allahabad
(2018). He has published 1 book, 10 book chapters, and over 60 research articles
in respected international journals. He has also served on numerous technical
program committees and organizing committees for various international
conferences.
Kamal Dua is currently a lecturer at the Graduate School of Health (Pharmacy),
University of Technology Sydney, Australia. He holds two doctoral degrees in
Pharmaceutical Sciences and Immunology & Microbiology, Master of Pharmacy,
MPharm(withaMajorinPharmaceutics),andBachelorofPharmacy(BPharm).He
hasalsobeenawardedfourprofessionaldiplomasintheareasofClinicalResearch,
Product Development, Drug Regulatory Affairs & Documentation and Intellectual
Property Rights (IPR). He has received various awards and fellowships for his
academicand professional achievements, including theExcellence Award inPhar-
macy (2018);Young Scientist Award (2011); andthe Sri. K.Sri HarshaMemorial
GoldMedal&RankCertificate(2004).
He also holds a conjoint lecturer position at the School of Biomedical Sciences
and Pharmacy, Faculty of Health and Medicine, The University of Newcastle,
Australia and Visiting Researcher at the Hunter Medical Research Institute
(HMRI) and Centre for Inflammation, Centenary Institute, Australia. He is also a
VisitingAcademicatvariousotheruniversities,includingtheSchoolofPharmaceu-
ticalSciences,UniversityofSãoPaulo,Brazil;SchoolofPharmaceuticalSciences,
Shoolini University; School of Pharmaceutical Sciences, Lovely Professional
University; and Saveetha Institute of Medical And Technical Sciences, Saveetha
University,India.
ix
x AbouttheEditors
His research experience spans 12 years which lies on the interdisciplinary
boundary between the acquired extensive knowledge on the application of the
principles of pharmacy (primarily formulation and pharmaceutics) to biomedical
sciences (immunology and microbiology). He has published 90 peer-reviewed
manuscripts in various respected pharmacy and pharmacology journals and has
authored2books,4bookchapters.
1
Oxidative Stress and Oral Diseases
Aravind Kumar Subramanian, Vivek Narayan, and R. Navaneethan
Abstract
Oral diseases such as dental caries, lichen planus, oral cancer, and most impor-
tantly chronic periodontitis are also believed to be linked to oxidative stress. In
periodontitis,theincessantpresenceofinflammationreleasesfreeradicalsandvia
various mechanisms such as DNA damage, lipid peroxidation, protein damage,
oxidationofantiproteases,andreleaseofpro-inflammatorycytokinescausesfree
radical-induced damage. The role of free radicals in carcinogenesis has been
studied for many decades. The free radicals cause DNA alterations such as
mutations, DNA-based oxidation, mutation of tumor suppressor genes, and
oxidative protein damage which facilitate the development of oral cancer. The
inflammatoryinfiltratepresentinorallichenplanushasCD4+lymphocytesandis
asourceofreactiveoxygenspecieswhichcausescellulardamage.Moreover,the
saliva itself has an antioxidant system which prevents free radical-mediated
damage in certain oral diseases. Hence this chapter is intended to provide an
insightaboutoxidativestressanditsassociationwithvariousoraldiseases.
Keywords
Oxidativestress·Periodontitis·Freeradicals·Oraldiseases·Oralcancer
A.K.Subramanian(*)·R.Navaneethan
DepartmentofOrthodontics,SaveethaDentalCollege,SaveethaInstituteofMedicalandTechnical
Sciences,SaveethaUniversity,Chennai,TamilNadu,India
V.Narayan
DepartmentofOralMedicineandRadiology,SaveethaDentalCollege,SaveethaInstituteof
MedicalandTechnicalSciences,SaveethaUniversity,Chennai,TamilNadu,India
#SpringerNatureSingaporePteLtd.2020 1
P.K.Maurya,K.Dua(eds.),RoleofOxidativeStressinPathophysiology
ofDiseases,https://doi.org/10.1007/978-981-15-1568-2_1