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Richard J Wood, Ph - University of Massachusetts Amherst PDF

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Richard J. Wood, Ph.D. Chenoweth 206 Department of Nutrition University of Massachusetts 100 Holdsworth Way Amherst MA 01003 E-mail [email protected] Tel # (413) 545-1687 FAX # (413) 545-1074 PROFESSIONAL EXPERIENCE 2009- Associate Professor, Department of Nutrition, University of Massachusetts, Amherst MA 01003 1991-2009 Scientist I, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St., Boston, MA 02111 1991-2009 Associate Professor, Gerald J. and Dorothy R. Friedman School of Nutrition, Tufts University, Boston, MA 1988-2009 Director, Mineral Bioavailability Laboratory, USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 1986-1990 Scientist II, USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 1986-1991 Assistant Professor, School of Nutrition, Tufts University, Medford, MA 1985-1986 Director, Mineral-Trace Element Laboratory, Clinical Nutrition Research Center, University of Chicago, Chicago, IL 1984-1986 Associate Director, Clinical Nutrition Research Center, University of Chicago, Chicago, IL 1984-1986 Assistant Professor, Department of Medicine, University of Chicago, Chicago, IL EDUCATION/TRAINING 1981-84 University of Chicago Postdoctoral, Clinical/Human Nutrition 1977-81 University of Connecticut Ph.D., Nutritional Physiology 1975-77 University of Connecticut M.S., Nutritional Sciences 1968-73 Boston University B.S., Biology RJ Wood CV August, 2012 PROFESSIONAL SOCIETIES: American Society for Nutrition American Physiology Society AREAS OF RESEARCH INTEREST: Diet-gene interactions; Mineral metabolism and aging; Molecular mechanisms of calcium transport; Vitamin D function, Micronutrient Bioavailability; Bioactive Food Components PROFESSIONAL SOCIETY SERVICE American Society Nutritional Sciences/ American Society for Nutrition (society name change)  Graduate and Professional Education Committee (2008-2011) o Vice-Chair (2008-2009) o Chair (2009-2011)  Nutrition Science Council o Chair, Web-based Communications Task Force (2008-2009)  Senior-Level ASN Award Committee o Member, 2010  Scientific Advisory Committee o Member, 2009-2011  Scientific Program Committee o Member, 2009-2011  Minority Affairs Committee o Member, 2009-2011  Proctor and Gamble-ASNS Graduate Student Award Committee o Member, (2000)  Mead Johnson Nominee Award Committee o Member, (2000-2002) Page 2 of 17 RJ Wood CV August, 2012 SCHOLARLY & PROFESSIONAL ACTIVITIES Nutrition Reviews o Associate Editor (1990-present) American Journal of Clinical Nutrition o Consulting Editor (2001-2009) Journal of Nutrition o Editorial Board Member (1994-2000) o Associate Editor, (2004-2010) International Meeting Organizer o Joint American Society for Nutrition-UK Nutrition Society Meeting, Cork, Ireland (2011) MANUSCRIPT/REPORT PEER REVIEW (Ad Hoc) Proceeding of the National Academy of Sciences (PNAS) Journal of Bone and Mineral Research American Journal of Physiology Endocrinology Journal of Clinical Endocrinology and Metabolism Journal of Nutrition American Journal of Clinical Nutrition Nutrition Reviews Archives of Biochemistry and Biophysics Digestive Diseases and Sciences Metabolism Journal of the American College of Nutrition Journal of Enteral and Parenteral Nutrition Nutrition Institute of Medicine Report (‘Daily Mineral Intakes for Military Personnel’) Institute of Medicine Report (‘Reducing Stress Fractures in Physically Active Military Women’) GRANT APPLICATION SCIENTIFIC PEER REVIEW National Institutes of Health Center for Scientific Review Nutrition Study Section 2003-2004, 2009, 2010 USDA CSREES Competitive Grants Nutrition Applications 1998 - 2004 The Wellcome Trust (UK) 2003 – 2004 Page 3 of 17 RJ Wood CV August, 2012 Scottish Research Foundation (UK) 2004 Veterans Administration 2001 INVITED INTERNATIONAL AND NATIONAL LECTURES Dannone Child Nutrition Conference. Sao Paulo, Brazil. 2010. “Calcium and Vitamin D Requirements in Children” Endocrinology Grand Rounds. University of Massachusetts Medical School. Worcester MA. 2008: “Vitamin D and the Metabolic Syndrome: An Update”. Pediatric Academic Societies Annual Meeting, Honolulu, HA, 2008: “Vitamin D, Adipogenesis, and Metabolic Syndrome”. 12th International Meeting Trace Elements in Man and Animals (TEMA 12), Colraine, N. Ireland, 2005: “HFE Polymorphisms, Iron Status, and Disease” 2nd International Congress International Academy on Nutrition and Aging. Albuquerque, NM (2003): “Intestinal Calcium Absorption: An Update” Institute of Medicine Food and Nutrition Board Workshop on Nutrition and the Human Genome. San Diego, CA (2003): “Microarrays and Gene Expression Profiling in Colonocytes” Eli Lilly Corporation. Indianapolis, IN (2003): “Vitamin D-mediated Transcriptional Profiling in Caco-2 Cells” American College for the Advancement of Medicine Annual Meeting. Ft Lauderdale, FL (2002): “Role of Vitamin K in Bone and Vascular Calcification” American Physiology Society - Experimental Biology Theme Session. New Orleans LA (2002): ”Hormonal Regulation of CaT1 Expression” University of Connecticut Health Science Center. Framington CT (2002): “Vitamin D- induced Calcium Transport and Gene Expression Profiling in a Human Intestinal Cell Line” Eli Lilly Corporation Skeletal Discovery Group. Kiawah Island, NC (2002): “Caco-2 Cells as a Model System to Study Vitamin D Effects on Intestinal Gene Expression” University of Connecticut Department of Nutritional Sciences Seminar. Storrs, CT (2001): “Modulators of Vitamin D-induced Ca Transport” Page 4 of 17 RJ Wood CV August, 2012 Harvard University Institute of Medicine Membrane Biology Group Seminar. Boston, MA (2001): “Vitamin D-induced Calcium Transport and Gene Expression in Caco-2 Cells” USDA Human Nutrition Research Center on Aging at Tufts University. Media Event: Nutritional Genomics, Boston, MA (2001): “Vitamin D Receptor Polymorphisms” Harvard University School of Public Health Department of Nutrition Seminar. Boston, MA (2001): “Vitamin D Regulated Calcium Absorption” American Heart Association Annual Meeting. San Antonio, TX (2001): “Poor Vitamin K Status is Associated with Severe Coronary Artery Calcification in Asymptomatic Elderly Measured by Electron Beam CT” Danone 4th International Conference on Functional Dairy Foods. New York, NY (2000): “Emerging Role of Functional Foods in Osteoporosis Prevention” Life Sciences Research Office - Workshop on the Bioavailability of Nutrients and Other Bioactive Compounds of Dietary Supplements: Defining the Research Agenda. Bethesda, MD (2000): “Bioavailability Methodologies” University of Granada, Granada, Spain (2000): “Mineral Bioavailability from Supplements” Tucuman Medical School, Tucuman, Argentina (2000): “Zinc in Clinical and Preventative Medicine” Augustus Justus University, Mendoza, Argentina (2000): “Zinc in Clinical and Preventative Medicine” Rosario Medical Society, Rosario, Argentina (2000): “Zinc in Clinical and Preventative Medicine” National Cattlemen’s Beef Association - Nutritional Research Discovery Symposium. Chicago, IL (2000): “Research Needs Relative to Dietary Zinc and Iron and the Role of Dietary Beef” American Home Products/Lederle Corporation. Pearl River, NJ (1999): “Assessing Bioavailability from Multi-Vitamin and Mineral Supplements” National Institutes of Health - Workshop on Zinc and Health: Current and Future Directions. Bethesda, MD (1999): “Assessment of Marginal Zinc Status in Humans” University of Wisconsin Department of Nutritional Sciences. Madison, WI (1999): ”New Molecular Insights into Iron Absorption” Page 5 of 17 RJ Wood CV August, 2012 Olie Foundation Annual Meeting. Boston MA (1999): “Mineral Issues in Parenteral Nutrition” International Symposium on Health Effects of Dietary Chromium, Dedham, MA (1998): “Future Directions in Chromium Research” Penn State University Department of Nutritional Sciences. College Park, PA (1997): Seminar on “Iron regulation of the hemochromatosis gene” Marabou Symposium: Diet-Gene Interactions. Stockholm, Sweden (1997): Conference discussant Vitamin D receptor polymorphisms Institute of Medicine - Food & Nutrition Board: Panel on Ca and Related Nutrients ‘Workshop on Calcium, Vitamin D, Phosphorus, Magnesium, and Fluoride’. Washington DC (1996): “Functional Indicators and Criteria for Determining Calcium and Magnesium Adequacy Throughout the Lifespan” American Aging Association and American College of Clinical Gerontology Annual Meeting, San Francisco, CA (1996): “Nutrition, Genetic Markers and Bone Loss in the Elderly” Institute of Medicine- Food and Nutrition Board ‘Workshop on Assessing Readiness in Military Women: the relationship to nutrition’. Irvine, CA (1996): “Calcium Needs of Premenopausal Women” American Society for Parenteral and Enteral Nutrition– 20th Clinical Congress Washington DC (1996): ‘Nutritional Requirements Associated with Aging” University of North Carolina-Greensboro Department of Nutrition. Greensboro, NC (1995): “Mineral Requirements of the Elderly” University of Florida Department of Food Science and Nutritional Sciences, Gainsville FL (1995): “Mineral Requirements of the Elderly – Time to Reevaluate” Boston University College of Communication, Boston MA (1994): “Reporting on Food and Nutrition – and getting it right” US Environmental Protection Agency Workshop on Metal Bioavailability and Toxicity. Research Triangle Park, NC (1993): ‘Mineral-mineral interactions’. Page 6 of 17 RJ Wood CV August, 2012 RESEARCH FUNDING Extramural Grants National Institutes of Health- National Cancer Institute (Subcontract) “Iron and Inflammatory Biomarkers in Gastric Cancer in the ATBC Study” Role: PI: (2008-2009) National Institutes of Health (NIH RO1 DK64327) “Functional Role of CaT1 and Calbindin D in Calcium Transport” Role: PI (2003-2007) National Cancer Institute – Bioreliance Corporation (Subcontract BRC-55502-19) “Iron and Colon Cancer in the PLCO Study” Role: PI (2006) National Cancer Institute – Bioreliance Corporation (Subcontract BRC-1108-64) “Iron and Inflammatory Biomarkers and Colon Cancer in the ATBC Study” Role: PI (2004) USDA CSREES Competitive Grant (99-35200-7583) “Effect of Vitamin K Depletion and Repletion in Elderly Women on Calcium and Bone Metabolism” Role: PI (1999-2003) USDA CSREES Competitive Grant (95-37200-1673) “Vitamin D Receptor Genotypes and Calcium Metabolism in Postmenopausal Women” Role: PI (1995-1997) Bristol-Myers Squibb “High Calcium Liquid Diets and Dietary Zinc Requirements” Role: PI (1995-1996) USDA Food and Agricultural Sciences National Needs Graduate Fellowship (94-38420- 09710) “Phytochemicals and Human Nutrition” Role: Co-PI (1994-1999) Lederle Consumer Health “Calcium-Zinc Interactions in Postmenopausal Women” Role: PI (1994-1996) National Livestock & Meat Board “Dietary Pattern and Serum Ferritin in the Framingham Heart Study” Page 7 of 17 RJ Wood CV August, 2012 Role: PI (1994 – 1996) Intramural Grants USDA Contract and Cooperative Agreement to the Human Nutrition Research Center on Aging at Tufts University (CRIS# 1950-51520-009-01) “Diet-gene Interactions and Micronutrient Status” Role: PI (2004-2009) UMASS HATCH Grant “Effect of Sulforaphane on Vitamin D Receptor Function” Role: PI (2010-2012) PEER REVIEW PUBLICATIONS (115) Chapters (12) Wood RJ. Calcium and Phosphorus. In: Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 2e, ed. M Stipanuk. Elsevier, Ltd. 2006. page 887-920 Wood RJ, Ronnenberg A. Iron. In: Modern Nutrition in Health and Disease, 10th edition. Shike M, Ross AC, Caballero B, Cousins RJ, eds. Lippincott Williams & Wilkins. Baltimore MD. 2005. page 248-270. Wood RJ. Bioavailability: definition, general aspects and fortificants. In: Encyclopedia of Human Nutrition, 2e, ed. Cabellero B and Allen L. Elsevier Ltd. 2005 Wood RJ. Osteoporosis. In: Functional Diary Products. T. Mattila-Sandholm and M. Saarela, eds. Woodhead Publishing Limited. Cambridge, England. 2003. pp. 94-107. Wood RJ. Calcium and Phosphorus In: Stipanuk MH, ed. Biochemical and Physiological Aspects of Human Nutrition. 2000, Philadelphia: W.B. Saunders Co. pp.643-670. Serfaty-Lacrosniere C, Rosenberg IH, Wood RJ: The process of mineral absorption. In: Handbook of Metal-ligand Interactions in Biological Fluids, Bioinorganic Medicine. vol 1, G Berthon, ed. Marcel Dekker, Inc. New York. 1995; pp. 322-330. Allen LH and Wood RJ: Calcium and phosphorus. In: Modern Nutrition in Health and Disease, 8th edition. Shils ME, Olson JA and M Shik, eds. Philadelphia. Lea & Febiger 1994, 144-163. Wood RJ: Magnesium. In: Nutrition in the Elderly: The Boston Nutritional Status Survey. Smith-Gordon & Co Ltd. London, 1992, pp.163-8. Page 8 of 17 RJ Wood CV August, 2012 Wood RJ: Zinc. In: Nutrition in the Elderly: The Boston Nutritional Status Survey. Smith-Gordon & Co Ltd. London, 1992, pp.177-82. Wood RJ: Copper. In: Nutrition in the Elderly: The Boston Nutritional Status Survey. Smith-Gordon & Co Ltd. London, 1992, pp.183-8. Wood RJ, Serfaty-Lacrosniere C: Effects of gastric acidity and atrophic gastritis on calcium and zinc absorption in humans. In: Chronic Gastritis and Hypochlorhydria in the Elderly. Holt PR, Russell RM, eds., CRC Press, Inc, Boca Raton, FL, 1992, pp. 187-204. Bengoa, JM and Wood RJ: Magnesium. In: Absorption and Malabsorption of Mineral Nutrients. N.W. Solomons and I.H. Rosenberg, Eds., Alan R. Liss, Co., New York, 1984,p. 69-88. Reviews (26) Alzaim M, Wood RJ. Vitamin D and gestational diabetes. Nutr Reviews 2012: (accepted for publication). Maxwell CS, Carbone E, Wood RJ. Better newborn vitamin D status lowers RSV- associated bronchiolitis in infants. Nutr Reviews 2012: (In Press) Maxwell CS, Wood RJ. Update on vitamin D and type 2 diabetes. Nutr Reviews 2011: 69:291-295 Martini LA, Wood RJ. Milk intake and the risk of type 2 diabetes mellitus, hypertension and prostate cancer. Arq Bras Endocrinol Metabol. 2009 Jul;53(5):688-94. PubMed PMID: 19768259. Wood RJ. Manganese and birth outcome. Nutr Reviews. 2009 Jul;67(7):416-20. PubMed PMID: 19566601. Martini LA, Wood RJ. Vitamin D-blood pressure connection: update on epidemiologic, clinical and mechanistic evidence. Nutr Reviews 2008; 66:291-297. Wood RJ. Vitamin D and adipogenesis: new molecular insights. Nutr Reviews 2008: 66:40-46. Martini L, Wood RJ. Vitamin D and the metabolic syndrome. Nutr Reviews 2006; 64:479- 486. Wood RJ. The iron-heart disease connection: Is it dead or just hiding? Ageing Research Reviews 2004; 3:355-367. Page 9 of 17 RJ Wood CV August, 2012 Angelo G, Wood RJ. Novel intracellular proteins associated with cellular vitamin D action. Nutr Reviews 2002; 60:1-3. Wood RJ. The “anemic” enterocyte in hereditary hemochromatosis: molecular insights into the control of intestinal iron absorption. Nutr Reviews 2002; 60:144-147. Martini LA, Wood RJ. Assessing magnesium status: a persisting problem. Nutr Clinical Care; 2001; 4:332-337. Wood RJ. Assessment of marginal zinc status in humans. J Nutr 2000; 130:1350S-1354S Martini L, Wood RJ. Should dietary calcium and protein be restricted in patients with nephrolithiasis? Nutr Reviews 2000; 58: 111-7 Wood RJ. Rational design of multi-nutrient supplements. Nutr Clinical Care 1999; 2: 327- 8. Wood RJ, Fleet JC. The genetics of osteoporosis: Vitamin D receptor polymorphisms. Annual Rev Nutr 1998; 18: 234-257 Wood RJ, Han O. Recently identified molecular aspects of intestinal iron absorption. J Nutr 1998; 128: 1841-4. Whiting S, Wood RJ. Adverse effects of high calcium diets. Nutr Reviews 1997; 55:1-9. Whiting SJ, Wood R, Kim K. Pharmacology Update. Calcium supplementation. J Am Acad Nurse Practitioners 1997; 9:187-92. Fleming D, Wood RJ. Plasma transferrin receptor helps to predict iron deficiency in the anemia of chronic disease. Nutr Reviews 1995, 53: 167-169. Wood RJ, Suter PM, Russell RM. Mineral requirements of the elderly. Am J Clin Nutr 1995; 62:493-505. Wood RJ. Potassium bicarbonate supplementation and calcium metabolism in postmenopausal women: are we barking up the wrong tree? Nutr Reviews 1994; 52: 278-280. Wood RJ, Serfaty-Lacrosniere C: Gastric acidity, atrophic gastritis, and calcium absorption. Nutr Reviews 1992;50:33-40. Baker DH, Wood RJ: Cellular antioxidant status and human immunodeficiency virus replication. Nutr Reviews 1992;50:15-8. Wood RJ: Mineral needs of the elderly: developing a research agenda for the 1990s. AGE 1991; 14:120-8. Page 10 of 17

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MA. 1985-1986. Director, Mineral-Trace Element Laboratory, Clinical Nutrition 1984-1986. Associate Director, Clinical Nutrition Research Center, University of.
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