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Rhinology Review Samy Elwany Mohamed Askar 123 Rhinology Review Samy Elwany • Mohamed Askar Rhinology Review Samy Elwany Mohamed Askar Department of Otolaryngology Department of Otolaryngology Alexandria University Tanta Faculty of Medicine Alexandria, Egypt Tanta, Egypt ISBN 978-3-031-08793-6 ISBN 978-3-031-08794-3 (eBook) https://doi.org/10.1007/978-3-031-08794-3 © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023 This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland I dedicate this book to my small, lovely family: my wife, Maggie, my son Dino, and my daughter Nelly. I cannot express my love and gratitude to all of them for giving my life wonderful value and meaning. They are really the love of my life. I would also like to dedicate the book to all my students throughout my long career. Samy Elwany Special thanks to my backbone in my entire career of nasal surgery my wife Eman, my son Abdelrahman my daughters Bothyna and Alaa, my grandchildren Youssef, Mohamed, Ali, Layla, and Nelly. Special appreciation and respect to all my patients whom I believed I have helped to make them happier. Finally, I would like to thank my students and wish them a promising future. Mohamed Askar Preface The art and science of rhinology has greatly expanded during the last few decades. Several valuable well-written large textbooks are now available. While these text- books provide plethora of useful information, they may not be the ideal tool for those preparing for exams or needing quick to-the-point information. This illustrated book was written to serve as a concise and to-the-point resource and trainee companion for postgraduates setting for their fellowship, diploma, board, and similar exams, and also as a quick compact reference and refresher for otolaryngologists in their everyday practice especially as the e-book will be avail- able on smart phones and tablets. The book covers the full range of topics in the modern rhinology syllabus, as well as related important areas that may be encountered in today’s exams and practice. The topics of the book include basic sciences of rhinology, investigative rhinol- ogy, rhinologic symptoms and diseases, as well as office procedures and operations. The book also includes concise chapters on the basics of rhinoplasty and anterior skull surgery. All topics will be addressed in a comprehensive and comprehensible way to keep the book as a compact reference and revision aid. The book will distill key facts into bullet points for rapid access to essential information and will help otolaryngologists to better understand basic and clinical rhinology. Pictures, illustrations and videos were extensively used to complement the text. Each topic will be followed by MCQs with their answers for fast revisions. We hope the book will serve its purposes as a concise, time-saving resource detailing the essentials of rhinology and related topics for postgraduates and prac- ticing otolaryngologists. Alexandria, Egypt Samy Elwany Tanta, Egypt Mohamed Askar vii Contents 1 Development of the Nose, Paranasal Sinuses . . . . . . . . . . . . . . . . . . . . . 1 1.1 The Nasal Cavity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.2 The Paranasal Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 1.3 The Ethmoid Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 1.4 The Maxillary Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 1.5 Sphenoid Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 1.6 Frontal Sinus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2 Anatomy of Nose and Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2.1 The External Nose . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2.1.1 Surface Landmarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2.1.2 Structural Anatomy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 2.1.3 B lood Supply of the External Nose . . . . . . . . . . . . . . . . . . . . 11 2.1.4 Nerve Supply . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 2.2 The Nasal Cavity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 2.2.1 The Nasal Septum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 2.2.2 Lateral Basal Wall . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 2.2.3 B lood Supply of the Nasal Cavity . . . . . . . . . . . . . . . . . . . . . 17 2.2.4 N erve Supply of the Nasal Cavity . . . . . . . . . . . . . . . . . . . . . 17 2.3 The Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 2.3.1 The Ethmoid Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 2.3.2 The Maxillary Sinus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 2.3.3 The Frontal Sinus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 2.3.4 The Sphenoid Sinus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 2.4 Histology of the Nasal Mucosa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 3 Nasal Physiology and Functions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 3.1 Important Nasal Functions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 3.2 Olfaction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 3.3 Nasal Airflow and Conditioning . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 3.4 Defense Functions of the Nose . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 3.4.1 Mechanical Mechanisms . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 3.4.2 Humoral Mechanisms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 3.4.3 Cellular Mechanisms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 ix x Contents 3.4.4 Reflex Mechanisms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 3.5 Speech . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 4 Imaging of the Nose and Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 4.1 Computed Tomography (CT) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 4.2 Cone Beam CT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 4.3 Magnetic Resonance Imaging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 4.4 General Radiologic Findings of Inflammatory Lesions . . . . . . . . . . . 41 4.5 General Radiologic Findings of Neoplastic Lesions . . . . . . . . . . . . . 41 5 Investigative Rhinology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 5.1 Allergy Tests . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 5.1.1 Skin Prick Tests . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 5.1.2 Tests for IgE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 5.1.3 Nasal Smears . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 5.1.4 Blood Eosinophils . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 5.1.5 Nasal Provocation Test . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 5.2 Airway Tests . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 5.2.1 Rhinomanometry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 5.2.2 Acoustic Rhinometry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 5.2.3 Nasal Inspiratory Peak Flow . . . . . . . . . . . . . . . . . . . . . . . . . 47 5.3 Olfactory Tests . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 5.3.1 Subjective Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 5.3.2 Objective Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 5.4 Tests of Mucociliary Transport . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 5.5 Other Objective Tests . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 5.5.1 Nitric Oxide Measurement . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 5.5.2 Nasal Lavage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 5.6 Subjective Tests . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 5.6.1 SNOT 22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 5.6.2 NOSE Scale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 5.6.3 Visual Analog Scale (VAS) . . . . . . . . . . . . . . . . . . . . . . . . . . 49 5.6.4 Quality of Life (QOL) Questionnaires . . . . . . . . . . . . . . . . . . 49 6 Symptoms of Sinonasal Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 6.1 Epistaxis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 6.1.1 Vascular Anatomy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 6.1.2 The Sphenopalatine Artery (SPA) . . . . . . . . . . . . . . . . . . . . . 52 6.1.3 The Anterior and Posterior Ethmoid Arteries . . . . . . . . . . . . 53 6.1.4 Definition and Classification . . . . . . . . . . . . . . . . . . . . . . . . . 53 6.1.5 Primary (Idiopathic) Epistaxis . . . . . . . . . . . . . . . . . . . . . . . . 54 6.1.6 Secondary Epistaxis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 6.1.7 Management of Epistaxis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 6.1.8 First-Aid Measures. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 6.1.9 General Measures. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 6.1.10 Control of Bleeding . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 Contents xi 6.1.11 Treatment of the Cause . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 6.1.12 Hereditary Hemorrhagic Telangiectasia (Osler–Weber–Rendu Disease) . . . . . . . . . . . . . . . . . . . . . . . 57 6.2 Nasal Obstruction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 6.2.1 Classifications of Nasal Obstruction . . . . . . . . . . . . . . . . . . . 58 6.2.2 Etiology of Nasal Obstruction . . . . . . . . . . . . . . . . . . . . . . . . 58 6.2.3 Causes of Nasal Obstruction in Children . . . . . . . . . . . . . . . . 59 6.2.4 Assessment of Nasal Obstruction . . . . . . . . . . . . . . . . . . . . . 59 6.3 Olfactory Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 6.3.1 Classification of Olfactory Disorders . . . . . . . . . . . . . . . . . . . 60 6.3.2 Causes of Olfactory Dysfunction . . . . . . . . . . . . . . . . . . . . . . 60 6.3.3 Assessment of Olfactory Function . . . . . . . . . . . . . . . . . . . . . 61 6.3.4 Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 6.4 Headache . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 6.4.1 Tension Headache . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 6.4.2 Migraine Headaches. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 6.4.3 Cluster Headaches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 6.4.4 Neuralgias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 7 Choanal Atresia and Congenital Nasal Masses . . . . . . . . . . . . . . . . . . . 67 7.1 Choanal Atresia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 7.1.1 Clinical Picture. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 7.1.2 Investigations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 7.1.3 Differential Diagnosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 7.1.4 Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 7.2 Pyriform Aperture Stenosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 7.3 Congenital Nasal Masses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 7.4 Meningoceles and Encephaloceles . . . . . . . . . . . . . . . . . . . . . . . . . . 70 7.5 Gliomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 7.6 Nasal Dermoids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 8 Nasal Trauma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 8.1 Foreign Bodies in the Nose . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 8.1.1 Clinical Picture. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 8.1.2 Investigations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 8.1.3 Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 8.2 Fractures of the Nasal Bones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 8.2.1 Types of Fracture of the Nasal Bones . . . . . . . . . . . . . . . . . . 77 8.2.2 Clinical Features . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 8.2.3 Investigations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 8.2.4 Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 8.3 Septal Hematoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 8.4 Fractures of the Midface (Le Fort Fractures) . . . . . . . . . . . . . . . . . . . 79 8.5 Frontal Sinus Fractures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 xii Contents 9 Nasal Septum, Nasal Valves, and Turbinates . . . . . . . . . . . . . . . . . . . . . 83 9.1 Septal Deviation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 9.2 Septal Perforations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 9.3 Nasal Valves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 9.4 The Turbinates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 9.4.1 Inferior Turbinates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 9.4.2 Middle Turbinate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 10 Rhinitis and Nasal Allergy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97 10.1 Classification of Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98 10.2 Allergic Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98 10.2.1 Classifications of Allergic Rhinitis . . . . . . . . . . . . . . . . . . . 99 10.2.2 ARIA Classification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99 10.2.3 Pathophysiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99 10.2.4 Comorbidities of Allergic Rhinitis . . . . . . . . . . . . . . . . . . . 99 10.2.5 Clinical Picture . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 10.2.6 Investigations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 10.2.7 Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 10.2.8 Aspirin-Exacerbated Respiratory Disease (AERD - Samter’s Triad) . . . . . . . . . . . . . . . . . . . . . . . . . . 102 10.2.9 Rhinitis and Asthma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 10.3 Non-Allergic Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 10.3.1 Etiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 10.3.2 Vasomotor Rhinitis (VMR) . . . . . . . . . . . . . . . . . . . . . . . . 103 10.3.3 Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 10.3.4 Non-Allergic Rhinitis with Eosinophilia Syndrome (NARES). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 10.3.5 Non-Allergic Inhalant/Occupational Induced Rhinitis . . . . 104 10.3.6 Hormonal Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 10.3.7 Food-Induced Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 10.4 Infectious Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 10.4.1 Acute Viral Rhinitis (Coryza - Common Cold) . . . . . . . . . 105 10.4.2 Scleroma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 10.4.3 Rhinosporidiosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 10.5 Special Types of Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 10.5.1 Drug-Induced Rhinitis (Rhinitis Medicamentosa) . . . . . . . 109 10.5.2 Atrophic Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 10.5.3 Primary Atrophic Rhinitis (Ozena) . . . . . . . . . . . . . . . . . . . 109 10.5.4 Secondary Atrophic Rhinitis . . . . . . . . . . . . . . . . . . . . . . . . 110 10.5.5 Rhinitis Sicca Anterior . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111 11 Rhinosinusitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 11.1 Acute Rhinosinusitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 11.1.1 Etiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 11.1.2 Microbiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116 11.1.3 Symptoms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116

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