Rheumatoid Arthritis, 2004 PDF
Preview Rheumatoid Arthritis, 2004
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William St. Clair Rheumatoid Arthritis are thoroughly covered in order to provide a firm foundation for the main focus of the text: therapy and clinical management of the disease Contents Clinical, Laboratory, and Radiologic Features 1. Epidemiology 2. Clinical Features and Differential Diagnosis 3. Prognosis and Clinical Course 4. Self-Report Questionnaires in Clinical Care 5. Clinical and Laboratory Measures 6. Autoantibodies and Other Laboratory Tests 7. Radiographic Findings 8. Measurement of Radiologic Outcomes 9. Ultrasonography and Magnetic Resonance Imaging for Diagnosis and Management Pathogenesis 10. Genetic Determinants 11. Pathology 12. Role of Cytokines 13. Angiogenesis and Leukocyte Recruitment 14. Neutrphils and Small Molecule Mediators 15. Complement and Other Aspects of Innate Immunity 16. T Cells in the Pathogenesis of Rheumatoid Arthritis 17. Autoimmunity 18. Immunosenescence and T-Cell Biology in Rheumatoid Arthritis 19. Synovial Fibroblasts 20. Cartilage and Bone Degradation 21. Mechanisms of Joint Damage in Rheumatoid Arthritis 22. Animal Models Therapy 23. Nonsteroidal Antiinflammatory Drugs and Analgesics 24. Corticosteroids 25. Methotrexate and Azathioprine 26. Sulfasalazine 27. Gold Compounds and Antimalarials 28. Minocycline 29. Cyclosporine 30. 31. 32. 27. 28. 29. 30. Leflunomide 31. Etanercept 32. Antibodies to Tumor Necrosis Factor: Infliximab and Adalimumab 33. Anakinra 34. Staphylococcal Protein A Columns 35. Combination Disease-Modifying Antirheumatic Drug Therapy 36. Treatment of Early Disease 37. Cognitive-Behavioral Therapy 38. Physical Therapy 39. Occupational Therapy 40. Medical Aspects of Surgery 41. Total Joints Arthroplasty 42. Hand and Wrist Surgery 43. Foot and Ankle Surgery 44. Cervical Spine Surgery Special Management Issues 45. Extraarticular Disease 46. Pregnancy 47. Osteoporosis 48. Depression Editors: St. Clair, E. William; Pisetsky, David S.; Haynes, Barton F. Title: Rheumatoid Arthritis, 1st Edition Copyright ©2004 Lippincott Williams & Wilkins > Front of Book > Editors EDITORS E. William St. Clair MD PROFESSOR OF MEDICINE AND IMMUNOLOGY DEPARTMENTS OF MEDICINE AND IMMUNOLOGY, DIVISION OF RHEUMATOLOGY AND IMMUNOLOGY, DUKE UNIVERSITY MEDICAL CENTER, DURHAM, NORTH CAROLINA David S. Pisetsky MD, PHD PROFESSOR OF MEDICINE AND IMMUNOLOGY DEPARTMENTS OF MEDICINE AND IMMUNOLOGY, DIVISION OF RHEUMATOLOGY AND IMMUNOLOGY; CHIEF OF RHEUMATOLOGY AND IMMUNOLOGY, DUKE UNIVERSITY MEDICAL CENTER, DURHAM VA MEDICAL CENTER, DURHAM, NORTH CAROLINA Barton F. Haynes MD FREDERIC M. HANES PROFESSOR OF MEDICINE; PROFESSOR OF IMMUNOLOGY DEPARTMENTS OF MEDICINE AND IMMUNOLOGY, DUKE UNIVERSITY SCHOOL OF MEDICINE; DIRECTOR, HUMAN VACCINE INSTITUTE, DUKE UNIVERSITY MEDICAL CENTER, DURHAM, NORTH CAROLINA WITH CONTRIBUTING AUTHORS Secondary Editors Danette Somers Acquisitions Editor Lisa Consoli Developmental Editor Mary Ann McLaughlin Supervising Editor Kate Sallwasser Production Editor Silverchair Science + Communications Colin Warnock Manufacturing Manager Brian Crede Cover Designer Compositor: Silverchair Science + Communications Printer: Quebecor World-Kingsport Contributing Authors Steven B. Abramson MD Professor of Medicine and Pathology Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, New York Graciela S. Alarc ³n MD, MPH Jane Knight Lowe Chair of Medicine in Rheumatology Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama School of Medicine, Birmingham, Alabama Ronald J. Anderson MD Associate Professor Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Harvard Medical School, Brigham and Women’s Hospital, Boston, Massachusetts Evangelos T. H. Andreakos BSc, DIC, PhD Senior Research Fellow Kennedy Institute of Rheumatology Division, Imperial College London Faculty of Medicine, London, United Kingdom William P. Arend MD Scoville Professor of Rheumatology Department of Medicine, University of Colorado School of Medicine, Denver, Colorado John Patterson Atkinson MD Samuel B. Grant Professor of Medicine; Professor of Molecular Biology Department of Medicine, Division of Rheumatology, Washington University School of Medicine, St. Louis, Missouri Catherine L. Backman PhD, OT(C) Associate Professor School of Rehabilitation Sciences, University of British Columbia Faculty of Medicine; Research Scientist, Arthritis Research Centre of Canada, Vancouver, British Columbia, Canada Philip E. Blazar MD Assistant Professor of Orthopaedic Surgery Department of Orthopaedics, Harvard Medical School, Brigham and Women’s Hospital, Boston, Massachusetts Ferdinand C. Breedveld MD Professor Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands Fionula M. Brennan BSc, PhD Professor of Cytokine Immunopathology Kennedy Institute of Rheumatology Division, Imperial College London Faculty of Medicine, London, United Kingdom S. Louis Bridges Jr. MD, PhD Associate Professor Departments of Medicine and Microbiology, University of Alabama School of Medicine, Birmingham, Alabama Nathalie D. Burg MD Postdoctoral Fellow Laboratory of Blood and Vascular Biology, The Rockefeller University, New York, New York Lisa C. Campbell PhD Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina Grant W. Cannon MD Professor of Medicine Division of Rheumatology, University of Utah School of Medicine; Associate Chief of Staff for Academic Affiliations, VA Salt Lake City Health Care System, Salt Lake City, Utah Wayne K. Cheng MD Instructor Department of Orthopaedics, Loma Linda University Medical Center, Loma Linda, California Philip G. Conaghan MB, MS, FRACP Senior Lecturer Department of Musculoskeletal Disease, University of Leeds School of Medicine, Honorary Consultant, Leeds General Infirmary, Leeds, United Kingdom R. Lee Cothran Jr. MD Clinical Associate Department of Radiology, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina Leslie J. Crofford MD Associate Professor Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Anne Davidson MBBS Professor Departments of Medicine and Microbiology and Immunology, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York Paola de Pablo MD, MPH Postdoctoral Fellow Department of Rheumatology, Immunology, and Allergy, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts Mark E. Easley MD Assistant Professor of Surgery Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina Paul Emery MA, MD, FRCP ARC Professor of Rheumatology; Head of Academic Unit of Musculoskeletal Disease Department of Musculoskeletal Disease, University of Leeds Medical School; Clinical Director, Leeds Teaching Hospitals Trust, Leeds, United Kingdom Angela Fairleigh OT (Reg) BC Department of Occupational Therapy, Mary Pack Arthritis Centre, Vancouver General Hospital, Vancouver, British Columbia, Canada Marc Feldmann MBBS, BSc, PhD, FRCP, FRCPath Professor of Immunology Kennedy Institute of Rheumatology Division, Imperial College London Faculty of Medicine, London, United Kingdom Beverley F. Fermor PhD Assistant Professor Department of Surgery, Duke University Medical Center, Durham, North Carolina Brian M. J. Foxwell BSc, PhD Professor of Immune Cell Signaling Department of Cytokine Biology and Cellular Immunology, Imperial College London Faculty of Medicine, London, United Kingdom Daniel E. Furst AB, MD Carl M. Pearson Professor of Rheumatology Department of Rheumatology, University of California, Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, California Cem Gabay MD Associate Professor of Medicine Departments of Internal Medicine and Pathology/Immunology, Division of Rheumatology, University Hospital of Geneva, Geneva, Switzerland Sherine E. Gabriel MD, MSc Professor of Medicine (Rheumatology) and Epidemiology Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota Renate E. Gay MD Professor of Experimental Rheumatology Department of Rheumatology, University of Zurich, University Hospital, Zurich, Switzerland Steffen Gay MD Professor of Experimental Rheumatology Department of Rheumatology, University of Zurich, University Hospital, Zurich, Switzerland Mary B. Goldring PhD Division of Rheumatology, Beth Israel Deaconess Medical Center, New England Baptist Bone & Joint Institute, Boston, Massachusetts Steven R. Goldring MD Division of Rheumatology, Beth Israel Deaconess Medical Center, New England Baptist Bone & Joint Institute, Boston, Massachusetts J ¶rg J. Goronzy MD, PhD Professor of Medicine Lowance Center for Human Immunology, Emory University School of Medicine, Atlanta, Georgia Peter K. Gregersen MD Professor of Medicine and Pathology Robert S. Boas Center for Genomics and Human Genetics, New York University School of Medicine, New York, New York, North Shore LIJ Research Institute, Manhasset, New York Farshid Guilak PhD Associate Professor Department of Surgery, Duke University Medical Center, Durham, North Carolina Boulos Haraoui MD, FRCPC Clinical Associate Professor of Medicine Department of Medicine, Universit © de Montr ©al, Faculty of Medicine, CHUM, H ´pital Notre-Dome, Montr ©al, Quebec, Canada Barton F. Haynes MD Frederic M. Hanes Professor of Medicine; Professor of Immunology
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