ee us i s are trd. Plea ke eaert ge bry ins Research Priorities for Airborne Paall s. ent ed ting filesetbeen acci Particulate Matter al typhave • III (cid:127) originmay Early Research Progress he ors m terr k, not froographic op oy er bme t Committee on Research Priorities for Airborne Particulate Matter p ao Board on Environmental Studies and Toxicology ps original ed, and Commission oCn oGmeomsicsiseinocne os,n E Lnivfeir oSncmienencet,s and Resources he ain National Research Council m tret oe ed frat bnnot ea es crer, c L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio PDF file: This new nal; line lengths, wnt version of this pu NATIONWAaLsh AinCgtAoDn,E DM.CY. PRESS About this to the origiuse the pri ee us ii s are trd. Plea eakerte NATIONAL ACADEMY PRESS 2101 Constitution Ave., N.W. Washington, D.C. 20418 ge bry ins NbeOrsT aIrCeE d:r Tawhen pfrroomjec tth teh acto uisn tchiles soufb tjheec tN oaf ttihoinsa rle Apocratd wemasy aopfp Srocvieendc besy, tthhee GNoavtieornnailn gA cBaodaermd yo fo tfh Ee nNgaintieoenrainl gR, easneda rtchhe CInosutintcuitle, owfh Moseed miceinme-. Paall The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance. s. ent This project was supported by Contract No. 68-C-98-003 between the National Academy of Sciences and the U.S. Environmental Protection ed ting filesetbeen acci AiLIlnyigtb eerrrenanfrcalyyet i.co otAf n tCnahlyeo Snovtgpiaerinwendsi aoso rnfCd st o,hB nfeoit nrooodkrlig nNNagnuusimm,z cabboteienorrc n:0 ls2u- 03osi00ro 19an0-gs09e,7 1no32cr3 i2re73es-c 5tohmatm pernodvaidtieodn ssu epxpporrets fsoerd tihni st hpirso pjeucbtl.ication are those of the author(s) and do not necessar- al typhave ANdatdioitnioanl aAl ccaodpeimesy o Pf rtehsiss r2e1p0o1r tC aoren satvitauitliaobnl eA fvroem., N: W Box 285 Washington, DC 20055 ginay 800-624-6242 202-334-3313 (in the Washington metropolitan area) http://www.nap.edu orim he ors Copyright 2001 by the National Academy of Sciences . All rights reserved. m terr Printed in the United States of America k, not froographic op oy er bme t p ao ps original ed, and he ain m tret oe ed frat bnnot ea es crer, c L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us iii s are trd. Plea ke eaert ge bry ins Paall s. ent ed ting filesetbeen acci al typhave ginay orim he ors m terr The National Academy of Sciences is a private, nonprofit, self-perpetuating society of distinguished k, not froographic stCecochhnongloarelrossg se yin nag na1dg8 e6tod3 ,ti hnthe sierc Aiuescneat idffoeirc m tahyne d gh eeannsge ari anmle waenreidlnfagatr ere e.t shUeaapt rorcneh qt,hu deier aedusi ctihato tteroid tay td oov fti hstheee ft hucehrt ahfreetderrae nrgacrlae ng otoefv dse ctroine mint cebeny ta tnohdne op er bome ty scientific and technical matters. Dr. Bruce M. Alberts is president of the National Academy of Sciences. p ao ps The National Academy of Engineering was established in 1964, under the charter of the National Academy original ed, and othfe S sceileenccteiosn, aosf a i tpsa mraelmlelb oerrgs,a snhizaaritniogn w oift ho uthtset aNnadtiinogn aeln Agicnaedeersm. yIt oisf Sauctioennocemso tuhse irne siptso andsmibiinliitsyt rfaotrio and vanisdi nign he ain the federal government. The National Academy of Engineering also sponsors engineering programs aimed at m tret meeting national needs, encourages education and research, and recognizes the superior achievements of oe ed frat bnnot engineers. Dr. William. A. Wulf is president of the National Academy of Engineering. ea The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the es crer, c services of eminent members of appropriate professions in the examination of policy matters pertaining to L filwev the health of the public. The Institute acts under the responsibility given to the National Academy of XMho Sciences by its congressional charter to be an adviser to the federal government and, upon its own initiative, m g, to identify issues of medical care, research, and education. Dr. Kenneth I. Shine is president of the Institute ed fromattin of Medicine. een recomposng-specific foron. TtaAhdhceve abi dNsreioanmatgdiyo tc,nh otaehml ef mRe Cdeueosneruiaatnylr c cgoihofl vshCceaoirsenu nbmnceceeci nlao tnwm.d aFe stu e tonchrhcegnt aipoonrlinoiznigencydgi pw biaynilt htaoh ctpehc eeNor rAaadttciiaonandngcea eaml gAwyeci’nstah cdp yegu mreopnfyo e bsoreoafs tlS h opc ftoi hefluneicrc Ntiehesaes tir dniino e1gnt9e ak1rlnm 6Ao itwcnoal eaeddsde sgbmoeyc y aita nhotdeef the original work has bation of and other typesettiding styles, for attributiauthoritative version StIrwhencwsesip etwsienct.ccuinteetianvest t eiaoilofnyfind c,M a oatlfh-ne aetddh c iNeeac ndaiNngteiaeimont.ni eioDaeenlsrr aA.i.on lB crgRagr ceudosecemmea mryMc uho. n fAC iEtolinbeugesn.irc ntTiselh .ea erni Cndg oD uinrn. c pWirlo iivlsl iiadadimnmg iA nse.i srWtveiruceeldfs ajtoorei nt hctlehy ag bioryvm ebaronntmh a Aenndct a,v dtiheceme piceuhsba laiinrcmd, aatnhnde, epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us iv s are trd. Plea ke eaert ge bry ins Paall s. ent ed ting filesetbeen acci al typhave ginay orim he ors m terr k, not froographic op oy er bme t p ao ps original ed, and he ain m tret oe ed frat bnnot ea es crer, c L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us v s are trd. Plea ke eaert ge bry ins COMMITTEE ON RESEARCH PRIORITIES FOR AIRBORNE PARTICULATE Paall MATTER s. ent ed ting filesetbeen acci JJG OU LDNEIANTT HRH CA. NC H S OA WASSM ,, E DTG ee(sCoerhrgta iRair e)I,ns eJsaotirhtcunhtse I Hnosfo tpTitkeuictnehs,n RUolenonigvoye, ,rN sAiettyvla,a ndBtaaaltimore, Maryland original typmay have RDB AOARNBTEIE RELT .S EC. .G RF O ROEERSE S,N T BCEARaU l,Mi fUo , rn nHiivaee aArlstiihrt y ER ofeffse oPcutesrn cInensssy tBlivtouaatnerid,a ,C SSacamhcobraormild oegfne tM, oMedaiscsianceh,u Psheitltasdelphia he ors P HILIP K. H OPKE , Clarkson University, Potsdam, New York m terr P ETROS K OUTRAKIS, Harvard University, Boston, Massachusetts ok, not fropographic PJD OAAEUN LLIE L.L M KIO YAR UE, DW UESRnKLiIvY ,e , r U sLintoyivv oeerfls aMicteye dRoifec sOinpteitr aaawtnodar, y DO Retnteatswiesatarr,yc O–hN nItneaswrtii otJuetres,e Ay,l bPuisqcuaetraqwuaey, New Mexico per bome ty RG OÜGNTEERR O O. MBE RCDCÖ LRESTLELRA N, ,U Anilvbeurqsuiteyr qouf eR, oNcehwes Mtere,x Ricoochester, New York ao original ped, and s RJR OEICYBHCEAEC RCEDA. SPP CAEHRNLKNEEINSRI N,, G GUEeRno i,rv geNere sWiwty aY sohof irMnkg iUtcohnnii gvUaennrsi,v iAteyrn sSnict yAh,o rWbool arosfh Mingetdoinci,n De,. CT.uxedo he ain F RANK E. S PEIZER , Harvard Medical School, Boston, Massachusetts m tret M ARK U TELL , University of Rochester, Rochester, New York oe ed frat bnnot RW O ANRARLEDN W W HHIITTEE , , AWmaesrhiicnagnt oLnu nUgn iAvsesrosictiya,t iSotn. Lanodu iNs, aMtioisnsaolu Oristeoporosis Foundation, Washington, D.C. es creer, ca TR EORNRAYL DF W. Y YOZSGIEA ,, AEmlecetrriicca nP oCwheerm Risetsreya Crcohu Inncsitli,t uAtrel,i nPgatloon A, Vltoir,g Cinailaifornia L filwev Mo m Xg, h Project Staff een recomposed frong-specific formattinon. JEMKNR O I AOULIHRYRLENSMBME AIHNOARD NN A ABOD G K L BAAM T KRA. E ,SOWR SH S SA,IS LtB ,AaS IL CSfSeAfS n- eETO inLLTofi , ,rof O i rScPEN SetrCdaritAifnatfRfco fOEir pVOfaIffCli fc Si,ec t raeInfrff oOrmffiacteiorn Specialist the original work has bation of and other typesettiding styles, for attributiauthoritative version TE RMAILCYIE S H M OALILB Y, ,S eSneinoiro Pr rPorjoejcetc At Asssissitsatnatnt epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us vi s are trd. Plea ke eaert ge bry ins BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY Paall s. ent G ORDON O RIANS (Chair), University of Washington, Seattle ed ting filesetbeen acci JID N OAGHVRNIID DD A C O .LU BLLEL UN ,R , KU UEn n,i vi Cveerosrlsiotiyrtya od ofo fK STateanxtseaa ssU, MAniuvesdetriicsniatly C, Feonrtet rC, oKlalinnssas City al typhave GT HLOENM RAS. BC UARSKS E, ,G Jeoohrngsia H Inosptkitiuntse U onf iTveecrshintyo,l oBgaylt, iAmtolaren,t aMaryland ginay W ILLIAM L. C HAMEIDES , Georgia Institute of Technology, Atlanta m the orierrors m JC OHHRNIS GTO EPRHHEARR BT. , F U IEnLivDe ,r sCitayr noef gCiea lIinfosrtintiuat,e B oefr Wkealesyhington, Stanford, California k, not froographic DJB. RAPUN ACIEUELL D SG.. HGIL MARMAEENMN ,O B CACKUe M,l e U,r a nH Giveeaenlrtoshimt Eyi cfofsef, cCRtsao lIcinfkosvtriinltluieat,,e M,D Caaavrmyislbanriddge, Massachusetts ooyp R OGENE H ENDERSON , Lovelace Respiratory Research Institute, Albuquerque, New Mexico er bme t C AROL H ENRY , American Chemistry Council, Arlington, Virginia p paso R OBERT H UGGETT , Michigan State University, East Lansing he original ained, and JJD AAAMMNEEIESSL FA K.. K MR EI TAWCCSH KMEI L, AL UH , On UNiv n,e i rvUseittrayshi to ySf toOaftt etW aUwinsaci,vo Oenrststiiantwy, ,Ma L, aOodgniastonarnio m tret C HARLES O'M ELIA , Johns Hopkins University, Baltimore, Maryland ed froeat be annot WAK N IIRNLK LP ES MO MW FIET. RHPS , A, US PSnCaiHcveIeE rURs in,t iy vH oeerfas Clitthyal iCSfcoohrunoniocali, l oB ofe fL rtkahewel e,N yWethhietrel aPnldaisn, sT, hNee Hwa Yguoerk es crer, c T ERRY F. Y OSIE , American Chemistry Council, Arlington, Virginia L filwev Mo Xh Senior Staff m g, ed fromattin DJ AAMVEIDS JJ.. PR OELISIAC A, N DSKirYe ,c t Aorssociate Director and Senior Program Director for Applied Ecology een recomposng-specific foron. RKKR .AOU JYBL MEBORIHORTNN BA DH M AA OK.. LSWWHMIE ,EAS D SP,S G rESEoL eg, ,nr P aiSomrero ngSDirtoaiarrmfe fPc ODrtoofirgfr ierfcaocemtrro t rhD feio rCre coRtmoisrmk f ioAtrtne Eea lnoyvnsii rsToonxmiceonltoalg Syciences and Engineering the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us vii s are trd. Plea ke eaert ge bry ins COMMISSION ON LIFE SCIENCES Paall s. ent M ICHAEL T. C LEGG (Chair), University of California, Riverside ed ting filesetbeen acci JFP OARAUENDLN EBRA IEBCRK UG RR (G.V EAiRc Ne, D CREhRuaStgOireN)r, s, S UCtananidfvwoerradsl iaUtdyne, riPv, ieWsrcsiaicttkyawe, rSastyha,an mNfoe r&wd , T JCearafstl,ei fyWoransiahington, D.C. al typhave JD AAMVEIDS SE.. EC ILSEEANVBEERRG , ,U Uninvievresristiyt yo fo fC Calailfiofronrinai,a S, Lano sF Aranngceislceos ginay N EAL L. F IRST , University of Wisconsin, Madison m the orierrors m DD AAVVIIDD JV.. GG AOLEADSD ,E LK ,e cTku Glarraikd,u Iantec .I, nSsotiututhte S oafn AFprapnliceidsc Loi,f Ce aSlcifioenrnciea, Claremont, California k, not froographic CJA ORONTR UWERYO. S G G. G OO RMODOEODZNM - ,PA NMO ,Mo PuUAnn t,i vS Ueinrnsaiiivt ySe rcoshfit oCyo aol lfoi ffCo Marnlieifado,i rcBniineare,k ,R eNlieveywer sYidoerk, New York ooyp D AVID G. H OEL , Medical University of South Carolina, Charleston er bme t B ARBARA S. H ULKA , University of North Carolina, Chapel Hill p paso C YNTHIA J. K ENYON , University of California, San Francisco he original ained, and DBD RAOUVNCIADEL MDR R.. LL. M EIVV IAINNTG T, SI TSEOOmNN o ,, r yMD Uaanrncaih-vF eoarfsr biDteyir,m CAeatsln,a cWnetrah ,Ii tnGes etPiotluragtienia,s ,B Nosetwon Y, oMrkassachusetts m tret E LLIOT M. M EYEROWITZ , California Institute of Technology, Pasadena ed froeat be annot RRR OOOBBNEEARRLTTD TRR... PSS AOEIKDNEAERL ,O , FU SFn t,a i vtNee orUsritnthyi v Coeafr srWoitlyian soahf i SNntgaettwoen UY, Snoiervkae,t trSlseittoyn,y R Balreoiogkh es crer, c C HARLES F. S TEVENS , The Salk Institute for Biological Studies, La Jolla, California ML filowev RS HAIYRMLEOYN DM L. .T W IL HGIHTME A, N D , N PAri nScceiteonnc eUsn, iIvnecr.s, iMtyo, uPnritnacine tVonie, wN,e Cwa Jliefrosrenyia Xh m g, ed fromattin Staff een recomposng-specific foron. JBWL AAA ACRURQBRRUAAEER TNLA I. RN BHE.. MKSO L.M LUPIIITD RRHA ,I YN, E C ,A Ex S de, ecm Fnuiiitnonivirase nPt rcDraiotaiigrlve rOeca tmAfofr isAcseosrsciisattaent the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us viii s are trd. Plea ke eaert ge bry ins COMMISSION ON GEOSCIENCES, ENVIRONMENT, AND RESOURCES Paall s. ent G EORGE M. H ORNBERGER (Chair), University of Virginia, Charlottesville, Virginia ed ting filesetbeen acci LRT YHICNOHNMA GARSD OE AL.D .G MC AR ONAN E,W D JEAoLYh ,,n sYU Hanloieop nUk iCnniasv reSbrcisdhietoy oC, lN oorefp wHo ryHagtaiiovenen ne(, R aCenotdinr Pendue)bc,lt iiScc. u HCtehaalrtlhe,s Btoanl,t iWmoesret ,V Miragriynliaand al typhave ET HUGOEMNAISA JK. GAL RNAAFYF , , UEnnivvierorsnimty eonft aMl Dareyfleannsde,, COoalklelgane dP, aCrkalifornia ginay D EBRA K NOPMAN , Progressive Policy Institute, Washington, D.C. m the orierrors m BH RUAGDH M C. OMON OERYR, IJS. ,B rEald D Moroaodnoe yG Aolsds oCcoirapteosr,a Ltiotdn.,, VAarlnincogutovne,r ,V Birrgitiinsiha Columbia k, not froographic HM. RILK TOnONoNAx LvRDi l PlUe SUSLELLILA M, , UJoninivt eIrnsisttyit oufte G feoorr gEian,e Argtyh eannsd Environment and University of Tennessee (Emeritus), ooyp R OBERT J. S ERAFIN , National Center for Atmospheric Research, Boulder, Colorado er bme t A NDREW R. S OLOW , Woods Hole Oceanographic Institution, Woods Hole, Massachusetts p paso EAN Z EN , University of Maryland, College Park original ed, and Staff he ain m tret R OBERT M. H AMILTON , Executive Director ed froeat be annot CJG E HRARENGIESOTTRITNYEE SH H .P OSEON YDNME , MR ASEOSdN ,m , Ai nSsicssiotercanittaiivtfeiec E aRnxedepc Fuoitrnitvsa enO cDfifaiirlce Oecrtfofircer es crer, c S ANDI F ITZPATRICK , Administrative Associate L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us ix s are trd. Plea ke eaert ge bry ins OTHER REPORTS OF THE BOARD ON Paall ENVIRONMENTAL STUDIES AND TOXICOLOGY s. ent ed ting filesetbeen acci original typmay have ATo Rxiicsko-loMgaicnaalg Eemffeecntts S otfr aMteegtyh yfolmr PerCcBur-yC (o2n0t0am0)inated Sediments (2001) he ors Strengthening Science at the U.S. Environmental Protection Agency: Research-Management and Peer-Review m terr Practices (2000) k, not froographic SMTcooixedinectloiiflnoigcg FiMcraoolnb Rtiilieesr-ksSs oi nou frD cSeeev lEeemclotiepsdms iFoelnnatsma (le 2T-0Ro0xe0it)caordloagnyt Canhdem Riicsakl sA (s2s0e0s0sm) ent (2000) op er bome ty CEcooplpoegri cina lD Inridnikciantogr Ws faotre trh (e2 0N0a0t)ion (2000) p ao ps Waste Incineration and Public Health (1999) original ed, and HReosremaorcnha lPlyri Aorcittiievse fAogr eAnitrsb ionr nthee P Eanrtviciruolnatme eMnta (t1te9r9: 9I.) Immediate Priorities and a Long-Range Research Portfolio he ain (1998); II. Evaluating Research Progress and Updating the Portfolio (1999) m tret Ozone-Forming Potential of Reformulated Gasoline (1999) oe ed frat bnnot RAirsske-nBica sined D Wrinakstien gC Wlasastiefric (a1t9io9n9 )in California (1999) ea Brucellosis in the Greater Yellowstone Area (1998) es crer, c The National Research Council's Committee on Toxicology: The First 50 Years (1997) L filwev Toxicologic Assessment of the Army's Zinc Cadmium Sulfide Dispersion Tests (1997) Mo Carcinogens and Anticarcinogens in the Human Diet (1996) Xh m g, Upstream: Salmon and Society in the Pacific Northwest (1996) een recomposed frong-specific formattinon. SWBRSRcciaeeoiinveetlkilnnoeaiccgwnneeidgc oaa s HM:nnf ddCaEaz hPrtJahkuaAreerdda' rgsoEsc m uEtn(es5dner aWnivrsnteit rgapiiocnseonst rreR meta sdiSne,s dinSk1t et p9BAase8l os cf9Musoi-eenr1oss d9R snAa9miert5cimoee)trn se(i tnd1( (1gi91a9 9la99 5n9A5)d4)c )tAiosnse (s1s9m9e4n)t Program (3 reports, 1994-1995) the original work has bation of and other typesettiding styles, for attributiauthoritative version PISPDsereosotsultttpieeinchscgi itdini nPnes gsr Rai ioVninsrd kiitst htiiAhebese isD l sfiTeotiyuesr s tniLsmna ao eINnfnn daIdt n tCu(if1osao9tnnnr9aytssl3 e (P)ar1van9ard9kt i2Cso) nahn i(ld1d 9rWe9n3i l)(d1e9r9n3es)s Areas (1993) epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri