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Rehabilitation of Revision ACL Reconstruction PDF

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Preview Rehabilitation of Revision ACL Reconstruction

Chapter 1 Rehabilitation of Revision ACL Reconstruction Michael B. Ellman, MD Rush University Medical Center, Chicago, Illinois Michael D. Rosenthal, PT, DSc, SCS, ECS, ATC, CSCS Naval Medical Center, San Diego, California Geoffrey S. Van Thiel, MD Rush University Medical Center, Chicago, Illinois Seth L. Sherman, MD Rush University Medical Center, Chicago, Illinois Matthew Provencher, MD Uniformed Services University of the Health Sciences, Bethesda, Maryland Naval Medical Center, San Diego, California Introduction nition of ACLR failure with the attempt to combine Reconstruction of the anterior cruciate ligament (ACL) both subjective data gathered from the patient and is widely accepted as the treatment of choice for objective data gathered by the clinician. They defined individuals with functional instability due to an ACL- failure as “functional instability with activities of daily deficient knee.1It is estimated that anywhere between living or sports and the knee shows increased laxity on 60,000 and 75,000 ACL reconstructions are performed physical examination and instrumented testing.”10 annually in the United States, although this number Based on this definition, it is estimated that approxi- may be as high as 350,000.2 Despite the fact that near- mately 8% of patients undergoing primary ACLR will ly 90% of index ACL reconstructions are performed by develop recurrent instability and proceed to graft surgeons who do fewer than 10 reconstructions per failure.10 year, the overall success rate of the operation is high, The evaluation, diagnosis, treatment and rehabilitation ranging from 75% to 95%.3,4 Nevertheless, between of failed ACLR is complex. Successful revision ACLR 3,000 and 10,000 revision ACL surgeries are performed requires an accurate diagnosis as to the cause of failure, each year, underlying the significant potential for failed appropriate pre-operative work-up, careful patient ACL reconstruction (ACLR).5 As adolescents maintain selection, a well-executed surgical plan, and individual- their participation in sports and older athletes extend ized rehabilitation protocols.7 Patient counseling and their playing days, the number of index ACL injuries management of pre-operative expectations are critical- continue to escalate each year.6Accordingly, as patient ly important. In general, it has been widely reported expectations and functional demands increase, the that the outcomes after revision ACLR are inferior to number of ACLR failures, with subsequent revision those following primary ACLR.3,5,7Even in the presence ACL surgery, will likely show a similar trend.7 of objective evidence of knee stability, subjective out- When evaluating a patient with persistent complaints comes may remain poor, possibly due to the declining following an index ACL surgery, the first and most status of the meniscus and articular surfaces.3,5-7,11 important step is to define what constitutes a failure of Return to pre-injury level of play is also less predictable the ACLR. Currently, there is a lack of general consen- after revision ACLR.3,5,7 Despite these challenges, the sus on what criteria define a failed ACLR. A low outcome of revision ACLR can be quite successful if the correlation exists between the patient's perception and treating team is attentive to detail, meticulous in pre- the surgeon's evaluation of knee stability following operative evaluation, and adherent to sound operative reconstruction.8,9 Safran and Harner10 proposed a defi- and rehabilitative principles.12 Modes of Failure likely be corrected with a revision ACLR, making post- Understanding the cause of failure is the pivotal first operative knee stiffness a potentially devastating step in evaluating the failed ACLR. It is critical to differ- complication, especially for high-level athletes. entiate between problems that can be helped by sur- Stiffness is best managed prophylactically by achieving gery, and those that are unlikely to change or improve full ROM pre-operatively and adherence to sound reha- with revision surgical intervention.1,7 In general, bilitation principles postoperatively. Loss of motion patients with a failed primary ACLR may present with secondary to arthrofibrosis may benefit from alterna- one of four major categories of complaints: recurrent tive treatment approaches such as arthroscopic lysis of patholaxity, decreased range of motion (ROM), exten- adhesions, and/or manipulation under anesthesia.7, 15 sor mechanism dysfunction, or issues with pain secondary to arthritis (Figure 1). Of these categories, the Extensor Mechanism Dysfunction most reliably treated with revision ACLR is recurrent Increased recognition and prompt treatment of patholaxity.3,5-7,11 Diagnosis and treatment of recurrent postoperative extensor mechanism deficiencies have patholaxity will be the significantly decreased the focus of the majority of the incidence of extensor chapter. The other three mechanism dysfunction problems have unique pre- over the past several years. sentations and treatment Classically, painful rehabil- algorithms that do not gen- itation in the early postop- erally involve revision erative setting induced ACLR. For completion, quadriceps muscle these causes of ACLR fail- shutdown. Deficient ure will be briefly quadriceps function cou- Figure 1: Causes of failed ACL reconstruction. discussed. pled with poor patellar mobility may lead to infra- Decreased ROM patellar contracture syndrome (IPCS), which is best The most common complication of ACLR is loss of diagnosed early and treated aggressively in rehab to knee motion, which has been reported to occur in up prevent long-term sequelae of joint contracture and to 35% of patients following primary ACLR.13-15 There patella infera.7,18 With the trend toward early aggressive are several causes of postoperative knee stiffness, rehabilitation protocols combined with increased including arthrofibrosis, prolonged immobilization, awareness about the effects of painful rehabilitation on complex regional pain syndrome (CRPS), capsulitis quadriceps inhibition, extensor mechanism dysfunc- with ligament scarring, impingement from an inade- tion is now a much less common cause of failed ACLR.7 quately debrided ACL stump, nonanatomic graft posi- tioning, and intercondylar notch scarring.16 Pain/Arthritis Specifically, arthrofibrosis, or malignant production of Pain as a cause of primary ACL failure can be due to fibrous tissue, is a significant challenge to the surgeon many factors. These include, but are not limited to, in the postoperative period. Knees reconstructed in the arthritis, infection (acute septic arthritis or chronic sub- acute setting after ACL surgery prior to regaining full clinical infection), CRPS, and recurrent or ongoing ROM pre-operatively are at greatest risk for arthrofibro- instability (including meniscal or osteochondral dam- sis,15 as pre-operative ROM is the greatest determinant age).7,10 Arthrosis should be suspected in the older of postoperative knee motion. patient returning with gradual onset of pain developing several years from the index procedure. Infection Loss of motion can be detrimental to outcomes of should be managed emergently to optimize the chance primary ACLR, potentially leading to decreased athlet- of graft survival and decrease the risk of joint degener- ic functional performance, altered running patterns, ation. CRPS requires multimodal non-operative and increased patellofemoral contact pressures with treatment methods for optimal outcome. Pain second- subsequent joint degeneration.3,5,14,16,17 Unfortunately, ary to recurrent or ongoing instability, with or without failures of primary ACLR due to loss of motion will not concomitant meniscal or osteochondral injury, may require revision ACLR.7,19 The evaluation and treat- tion of the graft in addition to favorable biomechanical ment of this subset of patients will be described in conditions (i.e. proper graft position and tension).22 more detail in the remainder of the chapter. Avascularity, immunologic reaction, and stress shield- ing may impede the ligamentization process and lead Recurrent Patholaxity to failure. Allograft use may also lead to delayed and Of the four main categories of postoperative ACLR fail- less organized biologic remodeling.23 ure, recurrent patholaxity is the failure mode most Clinically, true biological failures are rare and are a amenable to successful revision ACLR.2,3,5,6 To optimize diagnosis of exclusion. Most failures classified as biolog- outcomes, the specific cause of failure inducing recur- ic are secondary to mechanical problems preventing a rent patholaxity must be determined. This will ensure proper healing environment for the ACL graft such as a properly planned and executed revision ACLR with altered biomechanics or abnormal strain. True biolog- an individualized postoperative rehabilitation regimen. ical failures result in graft necrosis secondary to poor The causes of recurrent patholaxity can be further cat- revascularization, which may be caused by surgical fac- egorized into the following subgroups: Technical, tors such as overtensioning the graft, or patient factors Biologic, Traumatic, and Failure due to secondary insta- such as smoking, cocaine use, diabetes, or peripheral bility (Figure 1). vascular disease.7 Technical Traumatic Technical error at the time of primary ACLR is the The incidence of ACLR failure secondary to trauma is most common cause of failure requiring revision ACLR unknown. It has been reported to vary from 5-10% in and has been implicated in 77% of the cases leading to several series.7,20 Traumatic failure can be further divid- revision surgery.1,7 Intra-operative factors including ed into early and late failure, with early failures occur- non-anatomic tunnel placement, inadequate notch- ring in the first six months after surgery, prior to full plasty, improper graft tensioning, insufficient graft graft incorporation. Early failures in particular may material, and poor graft fixation rank amongst the involve overly aggressive physical therapy regimens or major shortcomings of index procedures that eventu- premature return to sport as the graft, especially at the ally fail.1 Non-anatomic tunnel placement accounts for points of fixation, is at its weakest in the acute postop- 70-80% of all technical errors, with the femoral tunnel erative setting.7,20,24 Late reruptures, in contrast, may the most likely to be malpositioned.1,20 Technical errors occur in an otherwise technically well-done ACLR. may lead to an increase in graft tension, graft impinge- Trauma of similar or greater magnitude to the initial ment, or rotational instability, all of which could result injury can potentially lead to graft failure and recurrent in eventual failure of primary reconstruction.1,7 More instability. Late rerupture usually occurs through the specifically, vertical placement of the femoral tunnel is mid-substance of the graft, similar to the location the most common technical error leading to revision where native ACLs fail.7,17 The incidence of late rerup- surgery. This error may produce a stable knee with ture is rare in a well-executed index autograft anteroposterior excursion but poor rotational stability.7 procedure.7 Biologic Failure of Secondary Stabilizers Biologic failure should be suspected in the patient with With an ACL injury, the magnitude of energy recurrent patholaxity without a history of trauma or necessary to rupture the ligament is substantial, and evidence of technical errors.1 These types of failures other structures of the knee are often injured concur- can be considered a failure of “ligamentization,” or rently. Unrecognized or unaddressed concomitant incorporation of the graft, as described by Amiel and knee injuries from the initial injury may lead to failure colleagues in 1986.21 Ligamentization is the process by of the ACLR. For example, posterolateral instability which a collagenous substitute, such as autograft or from an undiagnosed posterolateral corner (PLC) allograft tendon, undergoes remodeling and biologic injury is the most common unrecognized injury during incorporation to take on the role of the absent ACL. ACL rupture, and is present in 10-15% of chronically Successful incorporation relies on a favorable biologic ACL-deficient knees.1,17,25,26 Other concomitant injuries response from the host, which requires revasculariza- that may go unrecognized in the primary setting From a surgical perspective, an equally important include injuries to the menisci, medial collateral liga- piece of the history is reviewing previous medical and ment (MCL), lateral collateral ligament (LCL), and surgical documents to gain a better understanding of posterior cruciate ligament (PCL). Failure to address the index procedure. Reviewing the initial operative deficiencies in these knee stabilizers at the time of report provides important information on previous ACLR may lead to increased graft tension and eventu- surgical technique (one vs. two incision, open, endo- al failure. The ACL graft may initially provide anterior scopic, etc), type and source of graft, type of fixation restraint, but increased activity level will lead to grad- used, and status of menisci and articular surfaces at the ual recurrence of instability.4 time of surgery.7 Associated injuries to the articular surface and menisci are often more vital in predicting When considering revision ACLR, it is essential to subjective outcomes than recurrent patholaxity alone.27 evaluate these secondary restraints and address defi- ciencies within these structures at the time of surgery. Expectations Depending on the specific scenario, this may include Pre-injury and current activity level as well as patient combination procedures that involve revision ACLR expectations should be documented. It is crucial to rec- and PLC reconstruction or other related surgical proce- ognize that results of revision surgery are not as good dures that will be discussed in greater detail in the as those of primary ACLR,1 and the patient, physician sections to follow. Careful surgical planning and indi- and therapist must set realistic postoperative goals and vidualized rehabilitation protocols will help to ensure expectations. Kocher and colleagues clearly demon- successful outcomes in this group of patients. strated the importance of expectations in the revision ACL patient. They reported that false expectations pre- Patient Selection operatively may lead to a subjective failure of the revi- History sion procedure despite a successful revision surgery As with any surgical procedure, patient selection is from a technical standpoint.28 Often, the goals of revi- perhaps the most critical determinant of surgical sion ACLR are to allow the patient to return to activities outcome. In evaluating a patient with a failed ACL, of daily living without instability, rather than success- obtaining a thorough history is pivotal. Determining ful return to pre-injury level or sport, which may not be the patient's chief complaint may not only provide feasible. Rehabilitation after a revision is usually slow- clues as to the etiology of the failed graft, but it may er than after a primary reconstruction and patients also help guide treatment options. For example, if a need to understand that revision surgery is often con- patient's chief complaint after ACLR is pain, but he or sidered a salvage procedure, and their postoperative she demonstrates objective evidence of patholaxity on rehabilitation course will be more conservative. exam, even successful revision surgery may not allevi- ate symptoms. Next, the clinician should determine Physical Examination the symptoms that led the patient to have the index The physical exam of a failed ACLR patient should be ACL procedure in the first place, the time between thorough and consistent. There are several important initial injury and primary reconstruction, and the steps in obtaining an accurate diagnostic assessment of mechanism of injury. As noted, gaining a thorough the knee status post primary ACLR. First, the exam understanding of the patient's current symptoms, begins with observation of the patient's alignment including the presence or absence of pain, swelling, while weight bearing. Valgus or varus alignment may giving way, locking, and stiffness will help determine necessitate further imaging and prompt the clinician to both the mode of failure and the likelihood that surgery consider an osteotomy procedure, which will be dis- will be beneficial. Instability, rather than pain, should cussed later. The patient's gait should be observed for be identified before considering revision, as a painful a dynamic varus thrust, which may be seen in chronic knee that demonstrates some laxity on examination ACL-deficient knees indicating laxity of the PLC presents a different clinical scenario than a knee that structures, commonly found in the revision setting demonstrates recurrent instability. secondary to diagnostic failure prior to the index operation.26 The examination of the knee is similar to that for an ty and possible modes of failure of ACLRs previously index ACL injury. Skin should be examined for evi- discussed. MRI is a sensitive imaging modality in the dence of infection, as well as location and healing of diagnosis of concomitant injuries of the knee, most prior scars. ROM and patellar mobility may give an notably to soft tissue structures. Meniscal tears, articu- indication of cause of failure such as arthrofibrosis, lar cartilage injuries, osteochondral defects, joint contractures, or CRPS. Objective muscle strength LCL/MCL/PCL pathology, and PLC deficiency may all and functional testing help the clinician determine if be diagnosed on MRI, revealing an important step in further rehabilitation, bracing, or correction of gait pat- the understanding and management of revision ACL terns will be necessary prior to revision surgery.7 surgery.31,32 Tunnel osteolysis, while initially picked up Specific tests include the Lachman test, pivot shift, pos- on radiographs, may be further evaluated by computed terior drawer and sag testing for the PCL, assessment tomography (CT) scanning, which provides a better of LCL and MCL laxity (varus and valgus stress testing, definition of bony architecture than does MRI. Further, respectively), pain along the medial and lateral joint if there is concern for a subclinical infection, this must lines (meniscal injury vs. arthrosis), and integrity of be ruled out via joint aspiration and fluid culture, cell the PLC using the dial test. Importantly, the pivot shift count, gram stain and crystal analysis.7 test is a reliable clinical test for ACL deficiency that cor- relates well with patient-oriented outcomes.28,29 Indications and Contraindications However, this test may not be tolerated in the office set- Indications for revision ACLR include instability from ting secondary to pain and guarding by the patient. ACL deficiency with failed nonoperative management, Objective measures of ACL ligamentous laxity, such as normal mechanical alignment, and correctable concur- the KT-1000 (MEDmetric, San Diego, CA) are useful in rent meniscal, ligamentous, or cartilage damage. both the pre-operative and postoperative settings, with Contraindications are numerous and must be identi- a cutoff for an abnormal exam at >5 mm of side-to-side fied before proceeding with operative intervention. difference.11 For example, patients complaining of instability may present with quadriceps weakness secondary to inade- Imaging Studies quate rehabilitation rather than true ACL deficiency, For all patients with persistent complaints following and this must be ruled out as a cause of instability. If primary ACLR, a full set of knee radiographs should be the patient's chief complaint is pain, other sources of obtained, including weight bearing anteroposterior, failure should be identified. If the chief complaint is full-extension lateral, a 45-degree posteroanterior pain and instability, often concurrent pathology will flexion/weight bearing view, and axial views of the exist in addition to the primary ACLR failure. If the patella.7,30 Radiographs allow the clinician to assess for patient presents with malalignment and a failed ACL, evidence of arthritis, type and position of existing hard- attention must first be turned to correcting alignment ware, tunnel osteolysis, and patellar abnormalities before reconstructing the ACL, as it is not feasible to such as alta or baja that may complicate the clinical pic- correct soft tissue deficiencies with an underlying bony ture. Specifically, when evaluating for tibial or femoral abnormality. bone loss (tunnel osteolysis), serial radiographs are Similar to primary ACLR, it is necessary to obtain full helpful and should be evaluated to monitor for progres- ROM pre-operatively before revision surgery to prevent sion. Lateral views allow evaluation of tunnel position postoperative stiffness. Revision surgery is associated and size. A dedicated notch view may also be helpful in with greater stiffness pre-operatively and postopera- the revision setting to evaluate for inadequate notch- tively than primary ACL surgery secondary to a plasty, which has been implicated in the failure of number of factors, including arthrofibrosis and inade- primary ACLR.1 quate rehabilitation.33 If stiffness is significant and due Just as in primary ACL injuries, the use of advanced to arthrofibrosis, then it may be necessary to stage the imaging such as magnetic resonance imaging (MRI) is revision surgery to first regain ROM via arthroscopic not essential for the diagnosis of a failed ACLR. lysis of adhesions and aggressive rehabilitation, However, MRI is very helpful in evaluating the integri- followed by revision ACLR.7,33 Concomitant Conditions with the associated morbidity and additional risk of During the workup and evaluation of the patient with complications. a failed ACLR, secondary diagnoses may confound The advantages of using a patellar tendon autograft in operative treatment and postoperative rehabilitation. revision surgery include excellent graft strength/stiff- In the revision setting, concomitant conditions are ness, good fixation options, and predictable results in more common than with index ACL injuries. These active patients. Yet, these advantages must be coun- include PLC injuries, articular cartilage injuries, MCL tered against the disadvantages, including potential or PCL tears, patellofemoral problems, and varus or anterior knee pain, the risk of donor site fracture, and valgus malalignment. Whether diagnosed preopera- complications associated with operating on a normal tively or intraoperatively with subsequent procedures knee (in the case of a contralateral harvest). performed, concomitant conditions significantly affect both surgeon and physical therapist (PT) in the extend- The hamstrings represent another good source of auto- ed and often protracted postoperative course. Specific graft tissue for revision ACLR. The same disadvantages injuries will be discussed in greater detail in the and advantages for autograft hamstrings in the setting Surgical Treatment and Rehabilitation sections of this of primary ACL surgery hold true in the revision situa- chapter. tion. However, in the revision setting, the surgeon must take into account the size and location of the pre- Surgical Treatment vious bone tunnels. Often, these tunnels will either be Following the diagnosis of a failed ACLR and the too large or convergent with the new tunnels. This cre- determination of the etiology of failure, the surgeon ates a channel that is too wide to accommodate the may opt to proceed with operative intervention. hamstrings graft. The surgeon then has two options. If Before entering the operating room, however, pre-oper- the previous tunnels were non-anatomic, new ones ative planning is essential to properly manage the can be drilled in the appropriate anatomic position and underlying pathology. the previous tunnels can be ignored. If the tunnels present are too large for the graft, a two stage procedure Graft Selection can be completed that includes an initial bone grafting The first step in pre-operative planning is to choose a of the previous tunnel. graft for the reconstruction. This is similar to graft Lastly, a quadriceps tendon autograft can be used. selection in a primary ACL; however the coexisting This is a less common source of autograft. The con- pathology and previous procedures must be taken into cerns regarding the quadriceps tendon are similar to account. The ideal graft is one that retains strength at those for the patellar tendon given the fact that both least equivalent to that of the normal ACL, allows for require a removal of a bone block from the anterior secure fixation, has minimal morbidity, and allows for patella and can result in anterior knee pain as well as postoperative rehabilitation.34 The options for available potential patellar fractures. In the revision setting, a grafts can be broken down into two general categories, previous bone-patellar tendon-bone graft could poten- autograft and allograft. tially weaken the patella, and the subsequent removal of another bone block with the quadriceps graft may Autograft cause an intraoperative fracture. However, this has not There are multiple options for autograft reconstruc- been proven in the literature and remains theoretical. tion, including patellar, hamstrings, and quadriceps tendon grafts. Each graft has its own advantages and Allograft disadvantages in the revision setting. If the initial In revision ACL surgery, allograft tissue has become an (failed) reconstruction was done with an allograft, then extremely popular option and is used frequently. the ipsilateral patellar tendon represents an excellent Allografts have the advantage of being readily available option. If the patellar tendon was previously utilized, and are associated with less donor site morbidity, the treating surgeon has the contralateral patellar quicker operative time, decreased surgical dissection, tendon available. However, this carries the significant and are overall more cost-effective compared with disadvantage of operating on the patient's normal knee autografts.34 However, allografts will incorporate slow- grafting procedure involves clearing and identifying er than autografts and may therefore require an the ACL footprints and previous hardware on both tibia increased period of protection, and run the risk of dis- and femur, removing hardware as necessary, and bone ease transmission.34 Similar to autografts, there are grafting the previous tunnels using either allograft or multiple options for the revision ACL allograft. These autograft harvested from the iliac crest (Stage 1). The include patellar tendon, Achilles tendon, hamstrings patient is then given 4-6 months to allow incorporation tendon, as well as the tibialis anterior tendon allografts. of the bone graft, after which time the second stage can Each of these has their advantages and disadvantages, be completed in the same fashion as a primary ACL many of which are beyond the scope of this chapter. In reconstruction. particular, patellar tendon allografts are the most com- A technique for a one-stage revision ACLR with non- mon. These grafts offer excellent tensile properties anatomic initial tunnels is listed below. In most of with bone blocks that can be sculpted to fit the previ- these cases, the graft is placed either too vertical or too ous tunnel, thus improving fixation. The Achilles anterior, with the most common technical error being tendon has also become a popular graft in revision pro- vertical placement of the femoral tunnel. Therefore, cedures. It is a robust graft that has a large cross the femoral, tibial, or both tunnels may require place- sectional area and a customizable bone block. ment in new locations compared to the previous tunnels. Here, we present a brief technique guide for Surgical Techniques single bundle revision ACL reconstruction. Of note, The surgical techniques for a revision ACLR are both double bundle reconstruction is more commonly used varied and based on the etiology of failure. The follow- in primary ACLR than revision surgery, and is beyond ing sections will briefly discuss the specific surgical the scope of this chapter. techniques utilized to address various mechanisms of failure. 1. Diagnostic arthroscopy with removal of the remnant ACL and identification of appropriate The first subset we will discuss is the failed ACL with tunnel positions on both tibia and femur. A non-anatomic tunnels secondary to technical error, as notchplasty is also performed at this step. discussed previously. It is estimated that this is the eti- ology of failure in 70-80% of failed ACLRs.35 2. The tibial tunnel is drilled first from an incision on Misplacement of the initial tunnels can lead to graft the anterior tibia. If the previous tunnel does not impingement, ligamentous laxity, improper tension- converge with the new path, it can be left alone ing, and eventual graft failure.36 In these cases, pre- with or without hardware. operative planning is essential. Complete radiographs 3. If the exit point of the tibial tunnel is in the should be ordered, and a CT scan or MRI allows further appropriate position, and the surgeon wishes to evaluation of tunnel position, tissue integrity, and any create a new path for the graft, the “divergent concomitant knee pathology that may need to be tunnel” concept can be used. In this case, the new addressed at the time of revision. tunnel is created at a different angle (usually more horizontal) but with the same exit point inside the After complete evaluation, the surgeon must knee joint. determine the next course of action. If there has been significant expansion of the existing tunnels, a 2-stage 4. Now with the arthroscope, attention is turned procedure with bone grafting of the tunnels can be uti- toward the femoral ACL footprint on the medial lized. This 2-stage bone grafting technique is also use- aspect of the lateral femoral condyle. The old ACL ful in the setting of anticipated convergence between stump is identified and the location of the new the old and new tunnels. If the previous tunnels are tunnel is defined. clear of the anticipated new path, the surgery can pro- a. If the new tunnel is posterior to the old ceed in one step without bone grafting being neces- insertion, the previous hardware can be left sary. The other issue that the surgeon faces is the in place. However, given that the new hardware that was used to fix the original graft. If this tunnel may compromise the posterior wall, hardware will be in the way, then it must be removed intra-articular interference screw fixation intraoperatively. The basic technique for a 2-stage bone may not be possible. In these cases, fixation is achieved using a two-incision Clinically, patients may complain of instability coupled technique. This entails making a small with joint line pain and mechanical symptoms, more incision on the lateral aspect of the distal commonly medial than lateral with chronic ACL defi- femoral metaphysis to achieve fixation of ciency. Standard radiographs are obtained, with or the graft on the outer cortex of the femur. without an MRI to further evaluate meniscal and carti- b. If the previous femoral ACL stump is in the lage integrity. The findings on MRI for patients with correct location, two options exist. Either meniscal deficieny demonstrate a lack of meniscal tis- the use of the “divergent tunnel” concept as sue seen in the affected compartment on both coronal listed above, or the previous hardware and sagittal images (Figure 2A and 2B). must be removed and the old tunnel utilized. 5. With the technique defined and the insertion site localized, the surgeon now must determine if the femoral tunnel will be drilled through the tibial tunnel (trans-tibial), from an accessory anteromedial portal, or retrograde with the two- incision technique (special reamer required). One advantage of the accessory portal or retrograde cutter is that there is more flexibility with regard to femoral tunnel placement. This enables the surgeon to bypass the previous fixation. Figure 2a & b: MRI findings in patient with previous 6. After drilling and subsequent reaming of both tibial ACLR demonstrating deficiency of posterior horn of later- and femoral tunnels, the graft is passed and the al meniscus on T1-weighted coronal (2A) and sagittal choice of fixation is chosen. In general, there are (2B) images. two types of fixation; interference screw or fixation to the outer cortex of the tibia/femur with To best preserve the knee joint long-term, maintaining suspension fixation of the graft. intact menisci is of utmost importance in both index and revision ACL surgery. This creates a situation that Concomitant conditions necessitates management of both the ligament defi- Meniscal Injuries ciency and the meniscal pathology. In the initial Meniscal lesions and ACL tears commonly occur setting, unstable meniscal tears should be managed in together. The medial and lateral menisci act as shock conjuction with the primary ACLR. However, occa- absorbers in the knee, and the posterior horn of the sionally these tears will go undiagnosed or occur after medial meniscus is a secondary stabilizer to anterior- the index surgery and can potentially contribute to the posterior translation of the tibia on the femur. Removal failure of the original graft. In these cases, the menis- of even a small percentage of the meniscus (16-34%) cal tear should be addressed during the revision can significantly impact contact forces seen across the reconstruction with one of the follow techniques: knee, with up to a 350% increase in contact pressures 1) Partial Meniscectomy, 2) Meniscal Repair, or 3) in the medial compartment.37 It is well published that Meniscal Transplantation. the menisci influence both stability and load transmis- sion,38-41with an interdependence between the ACL and Meniscectomy medial meniscus.42 Patients undergoing a primary Meniscectomy is a straightforward procedure that ACLR with a medial meniscal-deficient knee have requires debridement and/or removal of the affected poorer outcomes than those without meniscal portion of the meniscus. This provides good pain relief deficiency due to an increase in contact pressures and but will not offer additional stability to the knee. The instability of the graft, and have higher rates of ACL effect of a meniscectomy on postoperative rehabilita- failure and revision surgery.17,37,43-46 tion is minimal. Meniscal Repair placing a bone block with both the anterior and poste- Meniscal repairs, in contrast, will significantly influ- rior meniscal horns attached into a slot created in the ence the postoperative protocol during ACLR, resulting tibia and securing the meniscus to capsule using an in limitations of ROM and weight bearing activities dur- inside-out meniscal repair technique. A screw may be ing the early stages of rehabilitation. In the setting of used to fix the bone block to the tibia, if needed. This an ACLR, meniscal repair of torn menisci have been approach is commonly used for lateral meniscal allo- shown to have high rates of healing secondary to graft transplant. The second technique, more common hematoma formation from ACLR,47 however this with medial meniscal transplants, utilizes bone tunnels depends on the type of tear. Tears involving the poste- that require the anterior and posterior meniscal allo- rior horn of the medial meniscus can significantly graft to be attached to two different bone plugs. These affect anteroposterior stability and should be repaired are then secured in the tibia via suture fixation. The in both primary and revision ACL procedures. Based ACL graft is then inserted, tensioned, and secured, as on the type of tear, different techniques and instru- previously described. ments can be used. For example, the surgeon will choose to use either an “all-inside” or “inside-out” tech- Cartilage Injuries nique to repair the meniscus back to capsule. “All- Cartilage injuries are common in patients with an inside” techniques use proprietary devices that secure acute ACL tear (25%) or chronic ACL deficiency the tear without having to make accessory incisions. (50%).48 In the ACL-deficient knee, chondral injuries “Inside-Out” techniques consist of a suture that is are classified as one of two types. The first is an acute passed through the torn meniscus on a needle that is chondral or osteochondral injury (i.e. osteochondral retrieved on the outside of the knee. Knots are then fracture) that is a result of the initial traumatic event, tied against the capsule through small incision. A mod- occurs more commonly in the lateral knee, and is like- ification of this using bone tunnels can sometimes be ly due to transient subluxation of the tibia on the femur used to repair posterior horn avulsions of the menis- and/or altered mechanical loading. The second type is cus. The ACL is then reconstructed using methods a degenerative lesion found in a chronically unstable described above. knee, resulting from long-term sequelae of the original insult or altered biomechanics from chronic instabili- Meniscal Transplant ty.49 The natural history of chondral lesions is largely In cases where the meniscus has been damaged unknown, but is thought to be more favorable in young beyond debridement or repair, or a significant portion and skeletally immature individuals and less favorable was previously removed with a meniscectomy, the in older patients.50 only way to recreate the secondary stabilizing effect of Clinically, diagnosis is often complicated because the the meniscus is through a meniscal transplantation. patient with a chondral lesion will have symptoms that This can be approached in either a staged or one-time overlap with ACL deficiency. In the revision setting, fashion along with the revision ACLR. Some surgeons cartilage injuries are difficult to diagnose and should be elect to complete the meniscal transplantation first and suspected in a patient with recurrent postoperative then come back at a later date for the ACLR. Others effusions or true mechanical symptoms following ACL elect to perform a one-stage meniscal transplantation. surgery (with no evidence of meniscal damage during Briefly, meniscal transplantation requires thorough first surgery). Overall alignment is important to deter- pre-operative planning to determine the size of the mine whether the patient is loading one compartment required allograft. Diagnostic arthroscopy is then per- over another, and may implicate the need for osteoto- formed with removal of the remnant meniscus and my to create a more favorable environment for carti- ACL. The anterior and posterior insertions for the lage restoration. A flexed knee radiograph can best meniscus are identified and a small arthrotomy is illustrate osteochondritis dissecans, posterior condyle made on the affected side for placement of the graft. degenerative disease, or posterior condyle osteochon- Preparation is then made for allograft docking, which dral lesions.49 MRI is valuable to further characterize can be done using two different techniques. The first lesions suspected on x-ray and allows for evaluation of involves use of a bone-bridge technique that involves defects that may significantly affect surgical interven- sent to a proprietary lab. In the lab, the chondrocytes tion.51 are isolated and reproduced exponentially. The patient is then taken back to the operating room, at which time Management of articular cartilage lesions can range the harvested cells are implanted into the cartilage from benign neglect to cartilage transplantation proce- defect via injection. A patch or glue is placed over the dures. The choice of treatment should be based on a top of the lesion to secure the cells in place, with the number of factors, including patient activity, age, depth goal of cartilage restoration. This procedure is current- and size of lesion, and intra-articular location. The lit- ly undergoing significant changes in contemporary erature is not clear with regard to what procedure is orthopaedics with the introduction of novel matrices best for each patient or lesion. Thus, the treatment is that better hold the cells and mimic the natural struc- surgeon-specific. Some of the primary procedures that ture of a cartilage matrix. Some of these techniques are can be considered in conjunction with a revision ACLR being used to create a one-stage process that does not are listed below. require the external incubation of a patient's cells. 1. Benign neglect- often symptoms induced by cartilage lesions will improve over time, and improved knee sta- MCL Injuries bility after ACLR can help make these defects less Concomitant ACL and medial collateral ligament symptomatic. (MCL) injuries frequently occur together, and have been classically termed as two-thirds of the “unhappy 2. Microfracture - This is technically the easiest triad,” along with medial meniscal injury.55 Recent procedure and some data suggests that this can be as studies report that MCL injury in the setting of an ACL effective as the more extensive cartilage procedures.52-54 tear can be as high as 20-38%.56,57Biomechanically, the It consists of creating small holes at the base of the ACL and MCL work together to limit anterior tibial lesion in order to stimulate and release pluripotent translation and valgus instability.58 The MCL complex, mesenchymal cells to aid in cartilage healing. At the including the superficial and deep MCL, resists valgus time of the diagnostic arthroscopy during revision ACL and external rotation forces of the tibia relative to the surgery, the lesion is identified and the calcified carti- femur, and acts as a secondary stabilizer to anterior lage layer is removed from the base of the defect. A translation.59 The mechanism of injury is usually a piv- microfracture awl is then introduced arthroscopically oting-type injury followed by immediate swelling and and used to create multiple subchondral holes that are pain on the medial side of the knee. The best physical spaced approximately 2-3 mm apart. When the tourni- examination test for MCL assessment is valgus stress quet is released, there should be bleeding evident from testing at 30 degrees of flexion. If the knee is unstable these holes. at both 0 and 30 degrees of flexion, classically the patient will have both an MCL and cruciate injury. 3. Osteoarticular Transplant System (OATS)- In this pro- cedure, an allograft is used to fill the cartilage defect. To date, treatment of MCL injuries when part of a This technique can be used for large and deep lesions. combined ACL-MCL injury is controversial, as some It is often done in a staged fashion in order to prevent studies have demonstrated that the MCL will heal well stiffness from occurring post-ACLR. Intraoperatively, with nonoperative treatment if the knee is protected, the lesion is defined and sized, and a corresponding while others report poor results following nonoperative plug is created in a femoral condyle allograft. This plug treatment.60-62 Nevertheless, relative indications for is then inserted into the patient's knee at the site of the repair or reconstruction of MCL injuries include three cartilage defect and secured with a bioabsorbable or more multiligamentous knee injury, intraarticular screw. entrapment of the MCL, failure of nonoperative treat- ment, and bony avulsion of the MCL insertion.58 In 4. Autologous Chondrocyte Implantation (ACI)- This tech- these situations, the surgeon may make the decision to nique requires harvesting and incubating the patient's repair the MCL during the revision ACL procedure. own chondrocytes and requires a two-stage procedure. In the first procedure, cartilage biopsies are taken from a non-articulating portion of the patient's knee and

Description:
ACL reconstruction (ACLR).5 As adolescents maintain Rehabilitation of Revision ACL .. of the bone graft, after which time the second stage can.
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