Regenerative Engineering Advanced Materials Science Principles CRC PRESS SERIES IN REGENERATIVE ENGINEERING SERIES EDITOR Cato T. Laurencin University of Connecticut Health Center, Farmington, Connecticut PUBLISHED TITLES Regenerative Engineering: Advanced Materials Science Principles Yusuf Khan and Cato T. Laurencin 3D Bioprinting in Regenerative Engineering: Principles and Applications Ali Khademhosseini and Gulden Camci-Unal Regenerative Engineering and Developmental Biology: Principles and Applications David M. Gardiner Regenerative Engineering Advanced Materials Science Principles Edited by Yusuf Khan and Cato T. 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Visit the Taylor & Francis Web site at www.taylorandfrancis.com and the CRC Press Web site at www.crcpress.com Contents Contributors, vii Chapter 1 ◾ Regenerative Engineering: Advanced Materials Science Principles 1 Mary Badon and yusuf Khan Chapter 2 ◾ Polymeric Hydrogels via Click Chemistry for Regenerative Engineering 11 Liangju Kuang, pauL a. LengeMann, and Meng deng Chapter 3 ◾ Bioactive Ceramics and Metals for Regenerative Engineering 31 ChangChun Zhou, Xiangfeng Li, junqiu Cheng, hongsong fan, and Xingdong Zhang Chapter 4 ◾ Substrate Guided Cell Behavior in Regenerative Engineering 53 Mengqian Liu and shyni Varghese Chapter 5 ◾ Bovine Tissue-Scaffold Interface Facilitates in vivo Evaluation of Tissue-Engineered Injectable Devices for Breast Tissue Reconstruction 71 CheryL t. goMiLLion, Karen j. L. Burg, and steVen e. eLLis Chapter 6 ◾ Application of Nanoscale Materials for Regenerative Engineering of Musculoskeletal Tissues 95 arijit BhattaCharjee, gariMa Lohiya, aMan Mahajan, M. sriraM, and dhirendra s. Katti v vi ◾ Contents Chapter 7 ◾ 3D Bioprinting for Regenerative Engineering 119 nathan j. Castro, Wei Zhu, haitao Cui, se-jun Lee, and Lijie graCe Zhang Chapter 8 ◾ Regenerative Engineering of the Human Using Convergence 139 Cato t. LaurenCin and naVeen nagiah INDEX, 149 Contributors Mary Badon Meng Deng Department of Orthopaedic Surgery Department of Agricultural and Biological University of Connecticut Health Center Engineering Farmington, Connecticut Purdue University West Lafayette, Indiana Arijit Bhattacharjee Department of Biological Sciences and Steven E. Ellis Bioengineering Division of Biological Infrastructure, Indian Institute of Technology Kanpur Biological Sciences Directorate Kanpur, Uttar Pradesh, India National Science Foundation Arlington, Virginia Karen J. L. Burg College of Veterinary Medicine Hongsong Fan University of Georgia National Engineering Research Center for Athens, Georgia Biomaterials Sichuan University Nathan J. Castro Chengdu, China Department of Mechanical and Aerospace Engineering Cheryl T. Gomillion The George Washington University College of Engineering Washington, District of Columbia University of Georgia Athens, Georgia Junqiu Cheng National Engineering Research Center for Dhirendra S. Katti Biomaterials Department of Biological Sciences and Sichuan University Bioengineering Chengdu, China Indian Institute of Technology Kanpur Kanpur, Uttar Pradesh, India Haitao Cui Department of Mechanical and Aerospace Yusuf Khan Engineering Department of Orthopaedic Surgery The George Washington University University of Connecticut Health Center Washington, District of Columbia Farmington, Connecticut vii viii ◾ Contributors Liangju Kuang Garima Lohiya Department of Agricultural and Biological Department of Biological Sciences and Engineering Bioengineering Purdue University Indian Institute of Technology Kanpur West Lafayette, Indiana Kanpur, Uttar Pradesh, India Cato T. Laurencin Aman Mahajan Department of Orthopaedic Surgery Department of Biological Sciences and University of Connecticut Health Center Bioengineering Farmington, Connecticut Indian Institute of Technology Kanpur and Kanpur, Uttar Pradesh, India Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Naveen Nagiah Engineering Sciences Institute for Regenerative Engineering Farmington, Connecticut University of Connecticut Health Center and Farmington, Connecticut Department of Materials Science & Engineering M. Sriram University of Connecticut Department of Biological Sciences and Storrs, Connecticut Bioengineering Indian Institute of Technology Kanpur Se-Jun Lee Kanpur, Uttar Pradesh, India Department of Mechanical and Aerospace Engineering Shyni Varghese The George Washington University Department of Bioengineering Washington, District of Columbia University of California San Diego, California Paul A. Lengemann Department of Agricultural and Biological Lijie G. Zhang Engineering Departments of Mechanical and Aerospace Purdue University Engineering, Biomedical Engineering, West Lafayette, Indiana and Medicine The George Washington University Xiangfeng Li Washington, District of Columbia National Engineering Research Center for Biomaterials Xingdong Zhang Sichuan University National Engineering Research Center for Chengdu, China Biomaterials Sichuan University Mengqian Liu Chengdu, China Department of Bioengineering University of California San Diego, California Contributors ◾ ix Changchun Zhou Wei Zhu National Engineering Research Center for Department of Mechanical and Aerospace Biomaterials Engineering Sichuan University The George Washington University Chengdu, China Washington, District of Columbia