Rediscovering cancer: from mechanism to therapy PDF
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REDISCOVERING CANCER REDISCOVERING CANCER From Mechanism to Therapy Edited by Sayali Mukherjee, PhD Somali Sanyal, PhD Sonia Chadha, PhD Apple Academic Press Inc. Apple Academic Press Inc. 3333 Mistwell Crescent 9 Spinnaker Way Oakville, ON L6L 0A2 Canada Waretown, NJ 08758 USA © 2019 by Apple Academic Press, Inc. Exclusive worldwide distribution by CRC Press, a member of Taylor & Francis Group No claim to original U.S. Government works International Standard Book Number-13: 978-1-77188-690-1 (Hardcover) International Standard Book Number-13: 978-1-351-16656-0 (eBook) All rights reserved. No part of this work may be reprinted or reproduced or utilized in any form or by any electric, mechanical or other means, now known or hereafter invented, including photocopying and record- ing, or in any information storage or retrieval system, without permission in writing from the publisher or its distributor, except in the case of brief excerpts or quotations for use in reviews or critical articles. This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission and sources are indicated. Copyright for individual articles remains with the authors as indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the authors, editors, and the publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors, editors, and the publisher have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowl- edged, please write and let us know so we may rectify in any future reprint. Trademark Notice: Registered trademark of products or corporate names are used only for explanation and identification without intent to infringe. Library and Archives Canada Cataloguing in Publication Rediscovering cancer : from mechanism to therapy / edited by Sayali Mukherjee, PhD, Somali Sanyal, PhD, Sonia Chadha, PhD. Includes bibliographical references and index. Issued in print and electronic formats. ISBN 978-1-77188-690-1 (hardcover).--ISBN 978-1-351-16656-0 (PDF) 1. Cancer. 2. Cancer--Etiology. 3. Cancer--Prevention. 4. Cancer--Treatment. I. Mukherjee, Sayali, editor II. Sanyal, Somali, editor III. Chadha, Sonia, editor RC261.R43 2018 616.99’4 C2018-903221-9 C2018-903222-7 Library of Congress Cataloging-in-Publication Data Names: Mukherjee, Sayali, editor. | Sanyal, Somali, editor. | Chadha, Sonia, editor. Title: Rediscovering cancer : from mechanism to therapy / editors, Sayali Mukherjee, Somali Sanyal, Sonia Chadha. Description: Oakville, ON ; Waretown, NJ : Apple Academic Press, 2018. | Includes bibliographical references and index. | Identifiers: LCCN 2018024997 (print) | LCCN 2018025644 (ebook) | ISBN 9781351166560 () | ISBN 9781771886901 (hardcover : alk. paper) | ISBN 9781351166560 (eBook) Subjects: | MESH: Neoplasms Classification: LCC RC263 (ebook) | LCC RC263 (print) | NLM QZ 200 | DDC 616.99/4--dc23 LC record available at https://lccn.loc.gov/2018024997 Apple Academic Press also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic format. For information about Apple Academic Press products, visit our website at www.appleacademicpress.com and the CRC Press website at www.crcpress.com CONTENTS About the Editors............................................................................................vii List of Contributors .........................................................................................ix List of Abbreviations .....................................................................................xiii Preface ..........................................................................................................xxi PART I: MOLECULAR MECHANISMS UNDERLYING INITIATION, PROMOTION, AND PROGRESSION OF CANCER ...............................1 1. Genetic Instability in Cancer ........................................................................3 Gloria Ravegnini, Patrizia Hrelia, and Sabrina Angelini 2. Oncogenesis and Telomerase Activity in Cancer .......................................21 Sutapa Mukherjee, Madhumita Roy, and Jaydip Biswas 3. Cell Cycle Checkpoints in Cancer ..............................................................59 Sreeparna Chakraborty and Abhik Sen 4. Angiogenesis, Its Importance, and Implication in Tumor Growth and Progression and in Anticancer Therapy: An Update .......................113 Chandrani Sarkar and Debanjan Chakroborty 5. The Tumor Microenvironment and Metastasis .......................................173 Sonia Chadha 6. Apoptosis: A Regulatory Mechanism in Cancer .....................................201 Sutapa Mukherjee, Apurba Mukherjee, Souvick Biswas, and Madhumita Roy 7. Cytoplasmic Signaling Circuitry: An Important Trait of Cancer .........223 Subhra Dash, K. Lohitesh, and Sudeshna Mukherjee PART II: CANCER ETIOLOGY: PHYSICAL, CHEMICAL, ENVIRONMENTAL FACTORS, AND GENETIC SUSCEPTIBILITY ....................................................................................251 8. Cancer: An Overview of Risk Factors ......................................................253 Sayali Mukherjee and Shabana Siddique vi Contents 9. Single Nucleotide Polymorphisms as Susceptibility Markers for Cancer ...................................................................................................287 Suresh Kumar Yadav and Somali Sanyal PART III: CANCER PREVENTION AND CONVENTIONAL THERAPIES .............................................................313 10. Dietary Phytochemicals in the Prevention and Therapy of Cancer: Modulation of Molecular Targets .............................................................315 Shamee Bhattacharjee 11. Health Benefits and Preventive Effects of Common Beverages in Cancer .....................................................................................................371 Vivek Kumar Gaur, Sanjay Gupta, and Janmejai Kumar Srivastava 12. Cancer Chemotherapy ...............................................................................407 Sonal Srivastava, Sakshi Mishra, Jayant Dewangan, Aman Divakar, Prabhash Kumar Pandey, and Srikanta Kumar Rath PART IV: NOVEL THERAPEUTIC APPROACHES FOR CANCER ...........................................................................................447 13. Non-Coding RNAs : The New Reins in Malignancies .............................449 Deba Prasad Mandal 14. Epigenetics in Cancer Prevention and Therapy: Role of Phytochemicals ..............................................................................493 Sajid Khan, Samriddhi Shukla, and Syed Musthapa Meeran 15. Cancer Stem Cell: Current Understanding and Future Perspectives .......527 Sonal Srivastava, Jayant Dewangan, Divya Tandon, and Srikanta Kumar Rath 16. Tumor Microenvironment and Cancer Stem Cells: Therapeutic Potential of Epigenetic Inhibitors to Target Cancer Stem Cells ............563 Anup Kumar Singh, Priyank Chaturvedi, and Dipak Datta 17. Nanoparticles in Cancer Therapy .............................................................581 Madhuchanda Banerjee 18. Cancer Immunotherapy: Extending New Horizons in Cancer Treatment .......................................................................................607 Deba Prasad Mandal Index ......................................................................................................................637 ABOUT THE EDITORS Sayali Mukherjee, PhD Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow, India Sayali Mukherjee, PhD, is an Assistant Professor at the Amity Institute of Biotechnology, Amity Univer- sity Uttar Pradesh, Lucknow, India. She completed her PhD from the Chittaranjan National Cancer Institute, Kolkata India, registered under Jadavpur University in Life Sci- ences. She received a NET-CSIR Research Fellowship. During her PhD she has worked on the toxicological and carcinogenic effects of air pollutants on human health. After completing her PhD, she has worked on stem cell cul- ture as a Research Associate at the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bangalore, India. Presently she is working on immunological and biochemical aspects of oral cancer and oral diseases. She has several publications in peer-reviewed journals of national and inter- national repute. Somali Sanyal, PhD Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow, India Somali Sanyal, PhD, is an Assistant Professor at Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow, India. She received her PhD from the Karolinska Medical University, Stock- holm, Sweden. During her PhD she has worked on molecular epidemiology of urinary bladder cancer. After her PhD she worked as a postdoctoral fel- low at the Karolinska Medical University, Stockholm, Sweden. Later on she moved to the Central Drug Research Institute, Lucknow, India, as a Research Associate. Her current research focuses on genetic aspects of head and neck, viii About the Editors oral, and gall bladder cancer. She has published several research articles in journals of national and international repute. Sonia Chadha, PhD Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow, India Sonia Chadha, PhD, is presently working as a fac- ulty member at the Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow, India. She completed her PhD from the Central Drug Research Institute, Lucknow, India, in biochemistry. During her PhD she has worked on the interaction of rat polymorphonuclear leukocyte derived free radical generation and nitric oxide in normal and in various pathological conditions. She has pursued her PDF from the National Environmental Engineering Research Insti- tute (NEERI), Nagpur, India, where she worked on cytochrome P450. Her research interests include biochemical and molecular aspects of cancer and hypertensive disorders. She has several publications in national and interna- tional peer-reviewed journals. LIST OF CONTRIBUTORS Sen Abhik Centre For Neurodegenerative Diseases, Blanchette Rockefeller Neurosciences Institute, West Virginia University, USA Divakar Aman Toxicological Division, CSIR–Central Drug Research Institute, Lucknow–226031, Uttar Pradesh, India Mukherjee Apurba Department of Environmental Carcinogenesis & Toxicology, Chittaranjan National Cancer Institute, 37, S.P. Mukherjee Road, Kolkata–700026, India Sarkar Chandrani Department of Pathology, The Ohio State University, 1645 Neil Avenue Columbus OH 43210, USA Chakroborty Debanjan Department of Pathology, The Ohio State University, 1645 Neil Avenue, Columbus OH 43210, USA Datta Dipak Biochemistry Division, CSIR–Central Drug Research Institute, Lucknow–226031, India Tandon Divya Toxicology Division, CSIR–Central Drug Research Institute, Lucknow–226031, India Ravegnini Gloria Department of Pharmacy and Biotechnology, Via Irnerio 48, Bologna, 40126, Italy Dewangan Jayant Toxicology Division, CSIR–Central Drug Research Institute, Lucknow–226031, India Biswas Jaydip Department of Environmental Carcinogenesis & Toxicology, Chittaranjan National Cancer Institute, 37, S.P. Mukherjee Road, Kolkata–700026, India Gaur Vivek Kumar CSIR–Indian Institute of Toxicology Research, M.G. Road, Lucknow, India Pandey Prabhash Kumar Toxicological Division, CSIR–Central Drug Research Institute, Lucknow–226031, Uttar Pradesh, India Rath Srikanta Kumar Toxicology Division, CSIR–Central Drug Research Institute, Lucknow–226031, India Singh Anup Kumar B Biochemistry Division, CSIR–Central Drug Research Institute, Lucknow–226031, India Srivastava Janmejai Kumar Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Lucknow–226028, Uttar Pradesh, India K. Lohitesh Department of Biological Sciences, Birla Institute of Science and Technology, Pilani, Rajasthan–333031, India
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