Recueil Des Travaux Chimiques Des Pays-Bas 1993: Vol 112 Index

12 Pages·1993·5 MB·French

Recueil des Travaux Chimiques des Pays-Bas 112 / 12, December 1993
Recl. Trav. Chim. Pays-Bas 112, 653-656 (1993)
Author Index
Adam, G., see Cutler, H.G. 467 Synthesis, conformations and redox properties of diametrical
Akkerman, O.S., see Gruter, G.-J.M. 425 calix{4Jarenediquinones 384
Albrecht-Gary, A.M. Cerfontain, H.
—, Dietrich-Buchecker, C.O., Guilhem, J., Meyer, M., Pascard, C. and —, Koeberg-Telder, A. and Lerch, U.
Sauvage, J.P. Electrophilic substitution of two monohomoperylenes and perylene
Dicopper (1) trefoil knots: Demetallation kinetic studies and molecu- 584
lar structures 427 Cerfontain, H., see Ansink, H.R.W. 210
Altona, C., see Quaedflieg, P.J.L.M. 15 Cerfontain, H., see Ansink, H.R.W. 216
Amabilino, D.B. Cerfontain, H., see Schonk, R.M. 201
- and Stoddart, J.F. Cerfontain, H., see Schonk, R.M. 247
A new approach to controlling catenated structures 429 Cerfontain, H., see Schonk, R.M. 457
Ansink, H.R.W. Chao, I.
—, Zelvelder, E. and Cerfontain, H. - and Diederich, F.
Sulfonation of 1- and 2-naphthol and their methanesulfonate esters Catalytic cyclophanes VII. Esterase activity of a bisimidazolyl-
with sulfur trioxide. The influence of initial sulfation on the sulfo- cyclophane 335
product composition 210 Chibante, L.P.F., see Heymann, D. 531
Ansink, H.R.W. Chibante, L.P.F., see Heymann, D. 639
—, Zelvelder, E. and Cerfontain, H. Chittenden, G.J.F., see Raaiïjmakers, H.W.C. 511
Sulfonation of a series of naphthalenes containing two different oxy Cleij, M.C.
substituents 216 —, Drenth, W. and Nolte, R.J.M.
Arnouts, E.G., see Raaijmakers, H.W.C. 511 Enantioselective cleavage of esters by histidine-containing tripeptides
Baart, A., see Mulder, P.P.J. 22 in micellar solutions of various hexadecvyltrialkylammonium bromide
Bakker, B.H., see Schonk, R.M. 201 surfactants 1
Bakker, B.H., see Schonk, R.M. 247 Comelli, E., see Casnati, A. 384
Bakker, B.H., see Schonk, R.M. 457 Copinga, S.
Banerjee, A.K. —, Dijkstra, D., de Vries, J.B., Grol, C.J. and Horn, AS.
_- and Vera, W. Synthesis and pharmacological evaluation of 5,6,7,8-tetrahydro-6-[pro-
Novel rearrangement during dehydration. Construction of the gua- pyl[2-(2-thienylethyljamino]-1,2-naphthalenediol: a novel non-
ianolide skeleton 259 selective dopamine-receptor agonist 137
Barf, T. Cornelisse, J., see Mulder, P.P.J. 22
—, Jansen, J.F.G.A., van Bolhuis, F., Spek, A.L. and Feringa, B.L. Cornelisse, J., see Mulder, P.P.J. 255
Self-assembling chiral metallo-clefts; synthesis and molecular struc- Cornelisse, J., see Mulder, P.P.J. 287
ture of N,N'-bis(12 H-benzolaJxanthen-12-ylidene)-1,2-ethane- Cutler, H.G.
diamine zinc(Il)-dichloride complex 376 —, Yokota, G. and Adam, eds., G.
Basten, J.E.M., see Spijker, N.M. 611 Brassinosteroids. Chemistry, Bioactivity, and Applications 467
Benckhuijsen, W., see de Goede, A.T.J.W. 567 Dargan, P., see Versloot, P. 273
Berden, J.A., see Groesbeek, M. 237 de Boer, J.S.A.M.
Berden, J.A., see Groesbeek, M. 303 - and Stam, CH.
Bickelhaupt, F., see Gruter, G.-J.M. 425 The influence of substituents on the geometry of the cyclopropane
Bijma, K. ring. VII The molecular and crystal structures of bicyclopropylidene
- and Engberts, J.B.F.N. (C;3H,=C;H,) and (dicyclopropylmethylene)cyclopropane [(C;-
The effect of chemical structure upon the thermodynamics of micel- H;),C=C;H,]. 635
lization of model alkylarenesulphonates. Prediction of micellar prop- de Boer, T., see Hermkens, P.H.H. 95
erties with the Poisson—-Boltzmann model 393 de Boer, Th., see Wieringa, J. 143
Bocchi, V., see Casnati, A. 384 de Goede, A.T.J.W.
Boere, B.B., see Mulder, P.P.J. 22 —, Benckhuijsen, W., van Rantwijk, F., Maat, L. and van Bekkum, H.
Boere, B.B., see Mulder, P.P.J. 255 Selective lipase-catalyzed 6-O-acylation of alkyl a-p-glucopyranosides
Boere, B.B., see Mulder, P.P.J. 287 using functionalized ethyl esters 567
Boersma, J., see Wissing, E. 618 de Goede, R.E.Y., see van den Broek, L.A.G.M. 82
Bolscher, J.G.M., see van den Broek, L.A.G.M. 82 de Groot, Ae., see Kesselmans, R.P.W. 226
Boons, G.J.P.H., see Smid, P. 451 de Haas, M.P., see Keegstra, E.M.D. 423
Born, J.G.P. de Jong, F., see van Straaten-Nijenhuis, W.F. 317
-, van der Wart, H.W.A., Mulder, P. and Louvw, R. de Meijere, A., see Schonk, R.M. 457
Gas-phase oxychlorination of benzene 262 de Mendoza, J.
Boryczka, S., see Maslankiewicz, A. 519 -, Prados, P., Campillo, N., Nieto, P.M., Sâchez, C.. Fayet, J.-P.
Bradshaw, eds., J.S., see Izatt, R.M. 516 Vertut, M.C., Jaime, C. and Elguero, J.
Brodesser, G., see Vôgtle, F. 325 Dipole moments can be used to determine the conformation of
Broekkamp, C.L.E., see Hermkens, P.H.H. 95 calix{4Jarenes 367
Brouvwer, A.M., see Scherer, T. 535 den Blanken, A., see Wieringa, J. 143
Broxterman, H.J.G., see Smid, P. 451 de Vries, E.F.J., see Groesbeek, M. 303
Bruggink, A., see van der Haest, A.D. 230 de Vries, J.B., see Copinga, S. 137
Cacciapaglia, R. de Zoete, M.C.
—, Mandolini, L. and van Axel Castelli, V. -, van Rantwijk, F., Maat, L. and Sheldon, R.A.
Alkali-metal-ion-assisted B,,2 cleavage of 2-(methoxycarbonyl)-1,3- Selective oxidation of penicillin G with hydrogen peroxide and with
xylylene-18-crown-5 by benzenemethanethiolate anion 347 enzymatically generated peroxyoctanoic acid 462
Campillo, N., see de Mendoza, J. 367 Diederich, F., see Chao, I. 335
Casnati, A. Dietrich-Buchecker, C.O., see Albrecht-Gary, A.M. 427
_-, Comelli, E., Fabbi, M., Bocchi, V., Mori, G., Ugozzoli, F., Lanfredi, Dijkstra, D., see Copinga, S. 137
A.M.M., Pochini, A. and Ungaro, R. Dijkstra, G.D.H.
654 Author Index
Conformational analysis of 1-arylpiperazines and 4-arylpiperidines a, w-Dipolar amphiphiles: Influence of rigid and flexible units on
151 aggregation behavior 339
Douvwes, M., see Verduyn, R. 464 Heymann, D.
Drenth, W., see Cleij, M.C. 1 - and Chibante, L.P.F.
Drenth, W., see Hansen, C.B. 497 Reaction of C;, and Cx With ozone at different temperatures 531
Drenth, W., see Huige, C.J.M. 33 Heymann, D.
Driessen, W.L. - and Chibante, L.P.F.
_-, Gorter, S., Haanstra, W.G., Laarhoven, L.J.J., Reedijk, J., Goubitz, Reaction of Cép, C0: C6: C78, and Cy4 With ozone at 23.5°C 639
K. and Seljée, F.R. Hezemans, A.M.F., see Huige, C.J.M. 33
Coordination properties of the didentate N,O ligand 1-(2-hydroxy- Hielkema, W., see Scherer, T. 535
ethyl)-3,5-dimethylpyrazole (HL). Crystal structure of [Cu- Hoogenraad, M., see Edema, J.J.H. 370
(HL),(NO;);] and [Cu(L)Br], 309 Horn, A.S., see Copinga, S. 137
Edema, J.J.H. Huige, C.J.M.
—, Hoogenraad, M., Schoonbeek, F.S., Kellogg, R.M., Kooïjman, H. —, Hezemans, A.M.F., Nolte, R.J.M. and Drenth, W.
and Spek, A.L. Molecular-mechanics calculation on oligomers of tert-butyl isocyanide
Alkylation of the S-C-S linkage. Towards lipophilic mono- and di- 33
topic heavy-metal receptors containing trithiane building blocks. Hulsbergen, F.B.
Molecular structure of cis-2,4,6-tribenzyl-1,3,5-trithiane 370 - and Reedijk, J.
Eijckelhoff, C., see Scherer, T. 535 Coordination compounds of tripeptides and pentapeptides containing
Elguero, J., see de Mendoza, J. 367 L-histidyl residues. Studies towards structural models for the active
Ellermann, L., see Hamm, P. 503 site of copper proteins 278
Engbersen, J.F.J., see Verboom, W. 549 Ippel, J.H., see Groesbeek, M. 237
Engbersen, J.F.J., see Weijnen, J.G.J. 351 Izatt, R.M.
Engbersen, J.F.J., see Weijnen, J.G.J. 525 - and Bradshaw, eds., J.S.
Engberts, J.B.F.N., see Bijma, K. 393 The Pedersen Memorial Issue 516
Erkelens, C., see Mulder, P.P.J. 287 Jaime, C., see de Mendoza, J. 367
Eveleens, S.M., see Raaijmakers, H.W.C. 511 Jansen, J.F.G.A., see Barf, T. 376
Fabbi, M., see Casnati, A. 384 Jauffret, P., see Hamm, P. 503
Fayet, J.-P., see de Mendoza, J. 367 Jenneskens, L.W., see Keegstra, E.M.D. 423
Feringa, B.L., see Barf, T. 376 Jones, FE.N., see Wicks, Jr., Z.W. 565
Gorter, S., see Driessen, W.L. 309 Katritzky, A.R.
Gosling, P.A. —, Rachwal, B., Rachwal, S., Smith, T.P. and Macomber, D.W.
—, Sijbesma, R.P., Spek, A.L. and Nolte, R.J.M. Preparation of dyes derived from Eriochrome Red B and Acid Alizarin
Synthesis and X-ray structure of a novel cavity-containing dinuclear Violet N soluble in organic solvents 552
nickel(II) complex 404 Kaufmann, G., see Hamm, P. 503
Goubitz, K., see Driessen, W.L. 309 Keegstra, E.M.D.
Goubitz, K., see Versloot, P. 273 —, Schouten, P.G., Schouten, A., Kooïjman, H., Spek, A.L., de Haas,
Groen, M.B., see Groen-Piotrowska, E.M. 627 M.P., Zwikker, J.W., Warman, J.M. and Jenneskens, L.W.
Groen-Piotrowska, E.M. Rapid charge migration within 1,4-benzoquinone stacks in the solid
- and Groen, M.B. phases of 2,5-di-n-decoxy-1,4-benzoquinone 423
Total synthesis of (+)-13-ethyl-3-methoxygona-1,3,5,911)-tetraen-17- Kelderman, E., see Verboom, W. 549
one via the tandem Claisen-ene strategy 627 Kellogg, R.M., see Edema, J.J.H. 370
Groesbeek, M. Kerkhof, F., see Scherer, T. 535
—-, de Vries, E.F.J., Berden, J.A. and Lugtenburg, J. Kesselmans, R.P.W.
The influence of the 5-methyl group in bacteriorhodopsin 303 —, Wijnberg, J.B.P.A., Schrijvers, R., Sudhôlter, E.J.R. and de Groot,
Groesbeek, M. Ae.
-, van Galen, A.J.J., Ippel, J.H., Berden, J.A. and Lugtenburg, J. Conformational analysis of cis-fused eudesm-11-en-4-ols 226
Three bacteriorhodopsins with ring-didemethylated 6-s-locked chro- Kleijn, H., see Wissing, E. 618
mophores and their properties 237 Klein Gebbink, R.J.M., see Martens, C.F. 400
Grol, C.J., see Copinga, S. 137 Koeberg-Telder, A., see Cerfontain, H. 584
Gronowitz, ed., S. Kooïijman, H., see Edema, J.J.H. 370
Thiophene and its Derivatives, part five 649 Kooïjman, H., see Keegstra, E.M.D. 423
Grootenhuis, P.D.J., see Koymans, L.M.H. 161 Koomen, G.J.
Gruter, G.-J.M. Synthesis and biological properties of selected nucleoside analogues
-, Akkerman, O.S., Bickelhaupt, F., Smeets, W.J.J. and Spek, A.L. 51
A remarkable halogen-zinc exchange reaction; X-ray crystal structure Koudijs, A., see Weijnen, J.G.J. 525
of (2-iodozincio-1,3-xylylene)-15-crown-4 425 Koväcs, L.
Guilhem, J., see Albrecht-Gary, A.M. 427 Methods for the synthesis of a-keto esters 471
Haanstra, W.G., see Driessen, W.L. 309 Koymans, L.M.H.
Haasnoot, C.A.G., see Koymans, L.M.H. 161 —, Grootenhuis, P.D.J. and Haasnoot, C.A.G.
Haasnoot, J.G., see Versloot, P. 273 Homology model-building studies of human thrombin: optimisation of
Hamm, P. modelling protocol and comparison with X-ray structure 161
-, Ellermann, L., Jauffret, P. and Kaufmann, G. Krijnen, B., see Scherer, T. 535
Perception and generalization of protective groups in the COSYMA Kuyl-Yeheskiely, E., see Quaedflieg, P.J.L.M. 15
system 503 Laarhoven, L.J.]J., see Driessen, W.L. 309
Hansen, C.B. Lanfredi, A.M.M., see Casnati, A. 384
-, Mul, G., Tabor, R.B.J. and Drenth, W. Laversanne, R., see Hessel, V. 339
Mechanistic study of decomposition of cyclohexyl hydroperoxide Lembeck, I., see Schonk, R.M. 247
catalysed by manganese{(Ill) tetraarylporphyrins 497 Lerch, U., see Cerfontain, H. 584
Harkema, S., see Verboom, W. 549 Leusen, F.J.J., see van der Haest, A.D. 230
Hayashida, O., see Murakami, Y. 421 Leysen, D., see Wieringa, J. 143
Heeres, G., see Wieringa, J. 143 Lie, T.S., see Woudenberg, R.H. 557
Hermant, R.M., see Scherer, T. 535 Louvw, R., see Born, J.G.P. 262
Hermkens, P.H.H. Lugtenburg, J., see Groesbeek, M. 237
-, Ottenheijm, H.C.J., van der Werf-Pieters, J.M.L., Broekkamp, Lugtenburg, J., see Groesbeek, M. 303
C.L.E., de Boer, T. and van Nispen, J.W. Lugtenburg, J., see Mulder, P.P.J. 22
CCK:-A Agonists: endeavours involving structure-activity relationship Lugtenburg, J., see Mulder, P.P.J. 255
studies 95 Lugtenburg, J., see Mulder, P.P.J. 287
Heskamp, B.M., see van den Broek, L.A.G.M. 82 Maat, L., see de Goede, A.T.J.W. 567
Hessel, V. Maat, L., see de Zoete, M.C. 462
-, Ringsdorf, H., Laversanne, R. and Nallet, F. Maat, L., see Meuzelaar, G.J. 573
Recueil des Travaux Chimiques des Pays-Bas 112 / 12, December 1993 655
Maat, L., see Woudenberg, R.H. 557 B-b-fructopyranosides; a convenient route to simple alkyl B-b-fruc-
Maat, L., see Woudenberg, R.H. 578 topyranosides 511
Macomber, D.W., see Katritzky, A.R. 552 Rachwal, B., see Katritzky, A.R. 552
Mandolini, L., see Cacciapaglia, R. 347 Rachwal, S., see Katritzky, A.R. 552
Martens, C.F. Rebek, Jr., J., see Pieters, R.J. 330
—, Sijbesma, R.P., Klein Gebbink, R.J.M., Spek, A.L. and Nolte, R.J.M. Reedijk, J., see Driessen, W.L. 309
X-ray structure of a molecular basket. Origin of its poor binding Reedijk, J., see Hulsbergen, F.B. 278
properties 400 Reedijk, J., see Versloot, P. 273
Maslankiewicz, A. Reichwein, A.M.
- and Boryczka, S. —, Verboom, W. and Reinhoudt, D.N.
4-Alkoxy-3'-(alkyithio)-3,4'-diquinolinyl sulfides and 4-alkoxy-3-(al- Binaphthyl metallomacrocycles for complexation of neutral molecules
kylthio)quinolines 519 358
Matsuura, S., see Murakami, Y. 421 Reichwein, A.M.
Meijer, C.W., see Schonk, R.M. 457 —, Verboom, W. and Reinhoudt, D.N.
Menge, W.M.P.B., see Vollinga, R.C. 123 Functionalized binaphthyl salophen crown ethers as models for the
Meuzelaar, G.J. enzyme urease 595
—, Woudenberg, R.H., Sinnema, A. and Maat, L. Reinhoudt, D.N., see Reichwein, A.M. 358
Synthesis of neopine and its 5B- and 7-substituted derivatives (chem- Reinhoudt, D.N., see Reichwein, A.M. 595
istry of opium alkaloids, part XL) 573 Reinhoudt, D.N., see van Straaten-Nijenhuis, W.F. 317
Meuzelaar, G.J., see Woudenberg, R.H. 578 Reinhoudt, D.N., see Verboom, W. 549
Meyer, M., see Albrecht-Gary, A.M. 427 Rijk, H., see Wieringa, J. 143
Miedema, F., see van den Broek, L.A.G.M. 82 Ringsdorf, H., see Hessel, V. 339
Mori, G., see Casnati, A. 384 Rissanen, K., see Vôgtle, F. 325
Morzherin, Y., see Verboom, W. 549 Roeters, T., see Wieringa, J. 143
Mul, G., see Hansen, C.B. 497 Sâchez, C., see de Mendoza, J. 367
Mulder, P., see Born, J.G.P. 262 Sauvage, J.P., see Albrecht-Gary, A.M. 427
Mulder, P.P.J. Scherer, T.
—-, Boere, B.B., Baart, A., Cornelisse, J. and Lugtenburg, J. —, Hielkema, W., Krijnen, B., Hermant, R.M., Eijckelhoff, C., Kerkhof,
Synthesis and spectroscopy of nine isomeric methylacephenan- F., Ng, A.K.F., Verleg, R., van der Tol, E.B., Brouwer, A.M. and
thrylenes 22 Verhoeven, J.W.
Mulder, P.P.J. Synthesis and exploratory photophysical investigation of donor-
-, Boere, B.B., Cornelisse, J. and Lugtenburg, J. bridge-acceptor systems derived from N-substituted 4-piperidones
Synthesis of dicyclopenta-fused derivatives of phenanthrene 255 535
Mulder, P.P.J. Schipper, F.J.M., see Smid, P. 451
—, Olde Boerrigter, J., Boere, B.B., Zuilhof, H., Erkelens, C., Cor- Schneider, H.-J.
nelisse, J. and Lugtenburg, J. NMR spectroscopy and molecular-mechanics calculations in
Synthesis and spectroscopy of nitroaceanthrylenes and nitroacean- supramolecular chemistry 412
threnes 287 Schonk, R.M.
Murakami, Y. —, Bakker, B.H. and Cerfontain, H.
—, Hayashida, O. and Matsuura, S. Reactions of cumulated and conjugated dienes with sulfur trioxide
Preparation and characterization of novel cage-type cyclophanes hav- 201
ing a helically twisted and cylindrical internal cavity 421 Schonk, R.M.
Nagasaki, T. —, Lembeck, I., Bakker, B.H. and Cerfontain, H.
—, Tajiri, Y. and Shinkai, S. Intramolecular competition in Friedel-Crafts sulfocyclization of w-
New water-soluble calixarenes modified with amino acids at the upper (1-naphthyl)-n-alkenes and 1,7-diphenyl-3-heptene on reaction with
rim 407 sulfur trioxide 247
Nallet, F., see Hessel, V. 339 Schonk, R.M.
N£g, A.K.F., see Scherer, T. 535 —, Meijer, C.W., Bakker, B.H., Zôllner, S., Cerfontain, H. and
Nieger, M., see Vôgtle, F. 325 de Meijere, A.
Nieto, P.M., see de Mendoza, J. 367 Reactions of methylenecycloalkanes and cycloalkylidenecycloalkanes
Nolte, R.J.M., see Cleij, M.C. 1 with sulfur trioxide 457
Nolte, R.J.M., see Gosling, P.A. 404 Schoonbeek, F.S., see Edema, J.J.H. 370
Nolte, R.J.M., see Huige, C.J.M. 33 Schouten, A., see Keegstra, E.M.D. 423
Nolte, R.J.M., see Martens, C.F. 400 Schouten, P.G., see Keegstra, E.M.D. 423
Nolte, R.J.M., see Sijbesma, R.P. 643 Schrijvers, R., see Kesselmans, R.P.W. 226
Olde Boerrigter, J., see Mulder, P.P.J. 287 Seljée, F.R., see Driessen, W.L. 309
Ottenheijm, H.C.J., see Hermkens, P.H.H. 95 Sheldon, R.A., see de Zoete, M.C. 462
Pandit, UK. Shinkai, S., see Nagasaki, T. 407
Programmed antibodies as tailor-made catalysts 431 Sijbesma, R.P.
Pappas, S.P., see Wicks, Jr., Z.W. 565 - and Nolte, R.J.M.
Pascard, C., see Albrecht-Gary, A.M. 427 Synthesis of concave receptors derived from diphenylglycoluril 643
Peters, J.A., see Venema, F.R. 445 Sijbesma, R.P., see Gosling, P.A. 404
Pieters, R.J. Sijbesma, R.P., see Martens, C.F. 400
- and Rebek, Jr., J. Sinnema, À., see Meuzelaar, G.J. 573
Convergent functional groups XIV. Synthesis and binding studies of Smeets, W.J.J., see Gruter, G.-J.M. 425
new molecular clefts for recognition and catalysis 330 Smid, P.
Pikkemaat, J.A., see Quaedfilieg, P.J.L.M. 15 -, Schipper, F.J.M., Broxterman, H.J.G., Boons, G.J.P.H.
Plate, R., see Wieringa, J. 143 van der Marel, G.A. and van Boom, J.H.
Ploegh, H.L., see van den Broek, L.A.G.M. 82 Use of (chloromethyl)dimethylphenylisilane in sugar chemistry.
Pochini, A., see Casnati, A. 384 Stereo-controlled approach to destomic acid and 1-deoxy-nojirimycin
Prados, P., see de Mendoza, J. 367 451
Put, J., see Versloot, P. 273 Smith, T.P., see Katritzky, A.R. 552
Quaedflieg, P.J.L.M. Soudijn, W., see van Wijngaarden, I. 126
—, Pikkemaat, J.A., van der Marel, G.A., Kuyl-Yeheskiely, E., Altona, Spek, A.L., see Barf, T. 376
C. and van Boom, J.H. Spek, A.L., see Edema, J.J.H. 370
Synthesis and physicochemical properties of decanucleotides contain- Spek, A.L., see Gosling, P.A. 404
ing (3 — 5’)-O-CH;,-O-linkages at predetermined positions 15 Spek, A.L., see Martens, C.F. 400
Raaijmakers, H.W.C. Spek, A.L., see Gruter, G.-J.M. 425
-, Eveleens, S.M., Arnouts, E.G., Zwanenburg, B. and Chittenden, Spek, A.L., see Keegstra, E.M.D. 423
G.J-F. Spijker, N.M.
Preparation and catalytic hydrogenolysis of some w-halogenoalkyl —, Basten, J.E.M. and van Boeckel, C.A.A.
656 Author Index
Unexpected phenomena in glycosylations of acceptors with L-idose Verboom, W.
configuration 611 -, Morzherin, Y., Kelderman, E., Engbersen, J.F.J., van Hummel,
Stam, C.H., see de Boer, J.S.A.M. 635 G.J., Harkema, S. and Reinhoudt, D.N.
Steenvoorden, J., see Wieringa, J. 143 Synthesis of 2,3-dihydro-1 H,4H,6H-fu]pryrorol[o{31,2,-a4 J-qubino -
Stoddart, J.F., see Amabilino, D.B. 429 line-6a(7H )-carbonitrile; a novel type of intramolecular tetrahydro-
Sudhôlter, E.J.R., see Kesselmans, R.P.W. 226 furan formation 549
Tabor, R.B.J., see Hansen, C.B. 497 Verboom, W., see Reichwein, A.M. 358
Tajiri, Y., see Nagasaki, T. 407 Verboom, W., see Reichwein, A.M. 595
Tan, M.C.A.A., see van den Broek, L.A.G.M. 82 Verduyn, R.
Tap, P.G.J.A., see Weijnen, J.G.J. 525 -, van der Klein, P.A.M., Douwes, M., van der Marel, G.A. and
Timmerman, H., see Vollinga, R.C. 123 van Boom, J.H.
Timmers, C.M. Polymer-supported solution synthesis of a heptaglucoside having phy-
-, van der Marel, G.A. and van Boom, J.H. toalexin elicitor activity 464
A note on the solid-phase synthesis of oligosaccharides by the Dan- Verhoeven, J.W., see Scherer, T. 535
ishefski approach 609 Verleg, R., see Scherer, T. 535
Tulp, M.Th.M., see van Wijngaarden, I. 126 Vermaas, D.J., see van den Broek, L.A.G.M. 82
Ugozzoli, F., see Casnati, A. 384 Versloot, P.
Ungaro, R., see Casnati, A. 384 —, Dargan, P., Haasnoot, J.G., Reedijk, J., van Duin, M., Put, J. and
van Axel Castelli, V., see Cacciapaglia, R. 347 Goubitz, K.
van Bakel, F., see Wieringa, J. 143 Reactivity of zinc dialkyldithiocarbamates towards halogen-sub-
van Bekkum, H., see de Goede, A.T.J.W. 567 stituted olefins 273
van Bekkum, H., see Venema, F.R. 445 Vertut, M.C., see de Mendoza, J. 367
van Boeckel, C.A.A., see Spijker, N.M. 611 Vôogtle, F.
van Boeckel, C.A.A., see van den Broek, L.A.G.M. 82 —-, Brodesser, G., Nieger, M. and Rissanen, K.
van Bolhuis, F., see Barf, T. 376 Binding of water and solvent molecules in a 25-membered-ring host
van Boom, J.H., see Quaedflieg, P.J.L.M. 15 compound 325
van Boom, J.H., see Smid, P. 451 Vollinga, R.C.
van Boom, J.H., see Timmers, C.M. 609 —, Menge, W.M.P.B. and Timmerman, H.
van Boom, J.H., see Verduyn, R. 464 A new convenient route for the synthesis of 4(5)-(w-aminoalkyl)-1H -
van Boom, J.H., see Zuurmond, H.M. 507 imidazoles 123
van der Klein, P.A.M., see Verduyn, R. 464 Warman, J.M., see Keegstra, E.M.D. 423
van der Marel, G.A., see Timmers, C.M. 609 Weijnen, J.G.J.
van der Marel, G.A., see Verduyn, R. 464 - and Engbersen, J.F.J.
van den Berg, K.J. Catalytic hydrolysis of phosphate esters by metallocomplexes of 1,10-
— and van Leusen, A.M. phenanthroline derivatives in micellar solution 351
Formation and [4 + 2] cycloaddition reactions of 2,3-dimethylene-2,3- Weijnen, J.G.J.
dihydrothiophene 7 —, Koudijs, A., Tap, P.G.J.A. and Engbersen, J.F.J.
van den Broek, L.A.G.M. Hydrolysis of 4-nitrophenyl esters of picolinic acid and N-protected
—, Vermaas, D.J., Heskamp, B.M., van Boeckel, C.A.A., Tan, M.C.A.A., amino acids by metalloenzyme models in vesicular assemblies 525
Bolscher, J.G.M., Ploegh, H.L., van Kemenade, F.J., de Goede, R.E.Y. Wicks, Jr., Z.W.
and Miedema, F. —, Jones, F.N. and Pappas, S.P.
Chemical modification of azasugars, inhibitors of N-glycoprotein- Organic Coatings. Science and Technology. Vol 1: Film Formation,
processing glycosidases and of HIV-I infection. Review and struc- Components, and Appearance 565
ture-activity relationships 82 Wieringa, J.
van den Meerendonk, A., see Wieringa, J. 143 -, van den Meerendonk, A., Steenvoorden, J., Heeres, G., van Bakel,
van der Haest, A.D. F., Roeters, T., van der Hulst, R., den Blanken, A., Leysen, D., de Boer,
—, Wynberg, H., Leusen, F.J.J. and Bruggink, A. Th., Rijk, H. and Plate, R.
Towards a rational design for resolving agents. Part V. Substituent Monoamine re-uptake inhibiting 1-[2-[(phenoxyphenyl)methoxyJeth-
effects in the resolution of ephedrine using a series of cyclic phospho- yllpiperazines as potential antidepressants 143
ric acids 230 Wijnberg, J.B.P.A., see Kesselmans, R.P.W. 226
van der Hulst, R., see Wieringa, J. 143 Wissing, E.
van der Marel, G.A., see Quaedflieg, P.J.L.M. 15 —, Kleijn, H., Boersma, J. and van Koten, G.
van der Marel, G.A., see Smid, P. 451 Regioselective introduction of functional groups in a-diimines by
van der Marel, G.A., see Zuurmond, H.M. 507 means of dialkylzinc compounds. Synthesis of functionalized 2- and
van der Tol, E.B., see Scherer, T. 535 3-pyrrolidinone derivatives 618
van der Wart, H.W.A., see Born, J.G.P. 262 Woudenberg, R.H.
van der Werf-Pieters, J.M.L., see Hermkens, P.H.H. 95 -, Lie, T.S. and Maat, L.
van Duin, M., see Versloot, P. 273 Reactions of thebaine and 6-demethoxythebaine anions with carbonyl
van Galen, A.J.J., see Groesbeek, M. 237 compounds; novel Diels-Alder adducts from 5B-substituted thebaines
van Hummel, G.J., see Verboom, W. 549 (chemistry of opium alkaloids, Part XXXIX) 557
van Kemenade, F.J., see van den Broek, L.A.G.M. 82 Woudenberg, R.H.
van Koten, G., see Wissing, E. 618 —, Meuzelaar, G.J. and Maat, L.
van Leusen, A.M., see van den Berg, K.J. 7 Synthesis of 7-substituted 6-demethoxythebaines and Diels-Alder re-
van Nispen, J.W., see Hermkens, P.H.H. 95 action of 7-methoxy-5B-methyl-6-demethoxythebaine (chemistry of
van Rantwijk, F., see de Goede, A.T.J.W. 567 opium alkaloids, part XLI) 578
van Rantwijk, F., see de Zoete, M.C. 462 Woudenberg, R.H., see Meuzelaar, G.J. 573
van Straaten-Nijenhuis, W.F. Wynberg, H., see van der Haest, A.D. 230
—, de Jong, F. and Reinhoudt, D.N. Yokota, G., see Cutler, H.G. 467
Macrocyclic carriers in supported liquid membranes 317 Zelvelder, E., see Ansink, H.R.W. 210
van Wijngaarden, I. Zelvelder, E., see Ansink, H.R.W. 216
-, Tulp, M.Th.M. and Soudijn, W. Zôllner, S., see Schonk, R.M. 457
Serotonin agonists and antagonists. Pharmacological tools and thera- Zuilhof, H., see Mulder, P.P.J. 287
peutics 126 Zuurmond, H.M.
Venema, F.R. -, van der Marel, G.A. and van Boom, J.H.
—, Peters, J.A. and van Bekkum, H. Potential usefulness of sugar 1,2 thio ortho esters in iodonium-promo-
Multinuclear-magnetic-resonance study of the coordination of alu- ted glycosidation 507
minium(IIl)-aldarate complexes with calcium(IT) in aqueous solution Zwanenburg, B., see Raaijmakers, H.W.C. 511
445 Zwikker, J.W., see Keegstra, E.M.D. 423
Vera, W., see Banerjee, A.K. 259
g"e—n"e s"
Recueil des Travaux Chimiques des Pays-Bas 112 / 12, December 1993
Recl. Trav. Chim. Pays-Bas 112, 657-663
Subject Index
abzymes, programmed antibodies, review, 431 atropine, in medicinal chemistry, 43
aceanthrenes, nitro—, 287 atropisomerism, fert-butyl isocyanide oligomers, MM, 33
aceanthrylenes, nitro—, 287 autobiographies, chemists, book, 652
acephenanthrylenes, methyl-, 22 aynchronous cycloaddition, 7-substd. 6-demethoxythebaine, 578
acetanilide, 4-chloro-, oxidative metabolism by cytochrome P450, 186 aza sugars, in medicinal chemistry, review, 82
acetonitrile, triethoxy-—, «-keto esters, synth., review, 471 aziridinylquinones, SAR, 174
(R)-1-acetyl-5-isopropoxy-3-pyrrolin-2-one, thesis, 515 azo dyes, derived from eriochrome red B and acid alizarin violet N, 552
N-acetylneuraminic acid, review, 471 azulene sesquiterpenes, cis-hydro-, thesis, 314
acid alizarin violet N, like dyes, 552 azulene, perhydro-, from dehydration of 1-(trimethylsiloxy)-decalin, 259
acrylic ester, in lipase-catalyzed 6-O-acylation of a-p-glucopyranosides, bacteriorhodopsins, labeling, thesis, 470; 237
567 bacteriorhodopsin, 5-methyl influence, 303
acrylonitrile, 2-ethoxy-, a-keto esters, synth., review, 471 BAL2, see nucleophilic cleavage of S,2 type
active site, in Cu proteins, 278 barium, binaphthyl metallomacrocycles, 358
acylase, in medicinal chemistry, review, 66 base-induced elimination, thesis, 469
N-acyliminium, ion precursor, thesis, 515 basket molecule, from diphenylglycoluril, crystal structure, 400
7-ADCA, in medicinal chemistry, review, 66 benzene, gas-phase oxychlorination, 262
adenine, receptor for hosts, 330 benzenediol, as [2]Jcatenane unit, 429
adenylosuccinate lyase, in medicinal chemistry, review, 51 benzenemethanethiolate, 18-crown-5, cleavage, 347
agonist-receptor interaction, in medicinal chemistry, 43 benzenesulfonates, micellization, thermodynamics, 393
AIDS, in medicinal chemistry, review, 82 benzodiazepines, nucleosides in medicinal chemistry, review, 51
aldarate, aluminum calcium complex, !H-, C-, !’O:., ?’AI-NMR, 431 benzonitrile, gas-phase oxychlorination, 262
alkali-metal ions, 18-crown-5, catalytic cleavage, 347 1,4-benzoquinone, 2,5-didecyloxy-, charge migration in solid phase, 423
alkaloids, see also opium alkaloids; neopine, 573; thebaine with car- benzola]xanthenylidene-1,2-ethanediamine, N,N'-bis-, ZnCl, complex,
bonyls, 557; thebaine, 7-substd. 6-demethoxy-, 578 crystal structure, 377
alkanes, book, 41 bicyclopropylidene, influence of substituents on geometry, 635
alkylarenesulfonates, micellization, thermodynamics, 393 bidentate, 1-(2-hydroxyethyl)pyrazole, 309
alkylidenetungsten(VI), in thesis, 470 binaphthyl metallomacrocycles, complexation, 358
alkynes, a-keto esters, synth., review, 471 binaphthyl salophen, crown ethers, 595
allene, sulfonation, 201 binary fluid mixtures, thesis, 272
allylic rearrangement, in neopine synth., 573 binding, see host-guest chemistry
aluminum, calcium aldarate complex, 1H-, ÉC., !7O., 7’AI-NMR, 431 biology, mass spectrometry, book, 236
amidoalkylation, molecular cavity from diphenylglycoluril, 643 biomedical polyurethane networks, thesis, 272
amine re-uptake, inhibited by piperazines, 143 bioreduction, aziridinylquinones, 174
amines, diphenylalkyi-, modulators of calcium and calmodulin, thesis, biosensors, third generation amperometric —, thesis, 39
314 biosynthesis, tetrapyrroles, book, 271
amino acids, calixarenes, modification, 407 bipyridines, cyclomeric — as host, 330
amino-acid sequence, CCK-A agonists, in medicinal chemistry, review, 95 4,4'-bipyridine, as [2Jcatenane unit, 429
amperometric biosensors, third generation —, thesis, 39 bisimidazolyl-cyclophanes, esterase activity, 335
amphiphiles, dipolar, 339 3-BMC, in medicinal chemistry, review, 66
analgesics, K-opioid receptor agonists, 169 books, advanced organic chemistry: reactions, mechanism, structure, 468;
anesthesine, in medicinal chemistry, 43 alkanes and cycloalkanes, chemistry, 41; autobiographies of chemists,
8-anilino-1-naphthalenesulfonate (ANS), calixarenes, modified with L-cy- 652; biosynth. of tetrapyrroles, 271; brassinosteroids, 467; carbohy-
steine, fluorescence, 407 drate antigens, 650; chirality in industry, 565; fused pyrimidines, 517;
announcement, Trends in Drug Research, Noordwijkerhout, 200 gas-phase ion chemistry, 518; inorganic chemicals handbook, 517;
annulation, furopyrroloquinolinecarbonitrile, 549 macromolecular science, 316; mass spectrometry in biology, 236;
[10]annulenes, 1,6-methano-, electrophilic substitution, 584 membrane chemistry, 315; natural products, 652; NMR, 651; organic
ANS, see 8-anilino-1-naphthalenesulfonate chemistry, 41; organic coatings, vol 1: films, 565; organic reactions,
antagonist-receptor interaction, in medicinal chemistry, 43 vol. 41, 516; organic synth., vol. 70, 652; organometallic chemistry of
antibodies, programmed as tailor-made catalysts, review, 431 transition metals, 467; organometallic chemistry, 315; organophospho-
anticancer agents, aziridinylquinones, 174 rus, 271; Pedersen memorial issue, 516; progress in heterocyclic chem-
antidepressants, piperazines, 143 istry, 315; pyrroles, 649; radical ionic systems, condensed phases, 42;
antidiarrhea agents, in medicinal chemistry, 43 reagents for organic synth., 468; Rodd’s chemistry of carbon com-
antiferromagnetism, Cu 1-(2-hydroxyethyl)pyrazole complex, 309 pounds, 2nd suppl., 650; stereochemistry of organic compounds, 42;
antigens, carbohydrates, book, 650 supramolecular chemistry, 651; tandem organic reactions, 518; thio-
antiglucocorticoid activity, mifepristone analog, 107 phenes, 649
antiprogestagens, 107 boron tribromide, O-demethylation in etorphine analogs, 113
antipsychotics, in medicinal chemistry, 43 bovine rhodopsins, labeling, thesis, 470
antisense, in decanucleotides with (3' — 5’)-O-CH;,-O- linkage, 15 brassinosteroids, book, 467
antitussives, in medicinal chemistry, 43 bromination, homoperylene, 584
antiulcer agents, in medicinal chemistry, 43 bromoalkenes, with Zn dialkyldithiocarbamates, 273
antiviral activity, in medicinal chemistry, review, 51, 82 N-bromosuccinimide, see succimide, N-bromo-—
6-APA, in medicinal chemistry, review, 66 tert-butyl isocyanide oligomers, MM, 33
arabinarate, aluminum calcium complex, !H-, °C-, !/O-, ?’AI-NMR, 431 tert-butyldimethylsilyl, protecting group, 123
armed””, thioglycosyl acceptor, 507 butyrophenone, type medicines, 43
aryl radicals, in benzene gas-phase oxychlorination, 262 CS, Ni, Pd conducting complexes, 314
arylpiperazines, conformation, 151 Co: With ozone, 531, 639
arylpiperidines, conformation, 151 C0: With ozone, 531, 639
asymmetric synthesis, contraceptive gonatetraenone deriv., 627 C6; With ozone, 639
658 Subject Index
C8, with ozone, 639 complexation, binaphthyl metallomacrocycles, 358; binaphthyl salophen
C4, With ozone, 639 crown ether uranyl complex, 595; NMR and MM of supramolecules,
CaA, zeolite, in lipase-catalyzed 6-O-acylation of a-b-glucopyranosides, review, 412; 2,4,6-tribenzyl-1,3,5-trithiane with Ag, 370
567 computational chemistry, thrombin, 161
cage-type cyclophanes, with cylindric and helical cavity, 421 computer graphics, K-opioid receptor agonists, 169
calcium, aluminum aldarate complex, !H-, lC-, !/O-, ?’AI-NMR, 431; computer-assisted organic synthesis (CAOS), COSYMA system, 503
diphenylalkylamines: modulators of — and calmodulin, thesis, 314 condensed phases, radical ionic systems, book, 42
calculation, arylpiperidines, conformation, 151; oxidative metabolism of conductors, based on M(C;,S;); and M(C;Se;);, thesis, 314; 2,5-didecyl-
4-chloroacetanilide by cytochrome P450, 186 oxy-1,4-benzoquinone in solid phase, 423; dipolar amphiphiles, 339
calix{4]arenes, dipole moment, conformation, 367; diquinones, 384; for conformation, arylpiperidines, 151, 151; calix{4jarenediquinones, 384;
heavy-metal-ion sensors, thesis, 40; macrocyclic carriers in mem- calix{4Jarenes, from dipole moment, 367; cyclophanes with cylindric
branes, review, 317; water-soluble, 407 and helical cavity, 421; deoxynojirimycin, in medicinal chemistry, re-
calix{élarenes, water-soluble, 407 view, 82; eudesm-11-en-4-ols, 226; tert-butyl isocyanide oligomers,
calmodulin, diphenylalkylamines: modulators of calcium and -, thesis, MM, 33; nitroaceanthrylenes and -aceanthrenes, 287; NMR and MM
314 of supramolecules, review, 412
CAOS, see computer-assisted organic synth. conjugated dienes, sulfonation, 201
carban-ions, a-keto esters, synth., review, 471 contraceptive steroid, gonatetraenone deriv., 627
carbazoles, cyclomeric — as host, 330 coordination, Co, Ni, Cu, Zn 1-(2-hydroxyethyl)pyrazole complexes, 309;
carbene adducts, of uridine derivs. in medicinal chemistry, review, 51 see complexation; L-histidyl-containing tri-and pentapeptides with Co,
carbohydrates, aluminum calcium aldarate, 'H-, BC-, 170-, Z’AI-NMR, Zn, Cu, 278; in WŸ! alkylidene chemistry, thesis, 470
431; antigens, book, 650; destomic acid and 1-deoxynojirimycin, 451; copper, 1,10-phenanthroline trefoil knot, crystal structure, 427; binding to
for chiral products, thesis, 314; a-p-glucopyranosides, lipase-catalyzed hosts, 330; 1-(2-hydroxyethyl)pyrazole complex, crystal structure, 309;
6-O-acylation, 567; glycosylation of acceptors with L-idose configura- proteins, 278
tion, 611; w-halogenoalkyl-B-b-fructopyranosides, 511; heptagluco- COSYMA system, protective groups, CAOS, 503
side, solid-phase synth., 464; nucleoside analogs in medicinal chem- counter-ion binding, alkylarenesulfonate micellization, 393
istry, review, 51; sialyltransferases, thesis, 470; solid-phase synth., 609; critical micellar concentration (CMC), calixarenes, modified with L-cy-
sugar 1,2-thio ortho esters, 507 steine, 407; dipolar amphiphiles, 339
carbon, C, and C with ozone, 531; Co, etc., with ozone, 639 crown ethers, binaphthyl salophen, 595; contg. benzenediol units, 429;
carbon-13, in labeled drugs, 191 macrocyclic carriers in membranes, review, 317; Pedersen memorial
carbon-14, in labeled drugs, 191 issue, book, 516; thia-—, 370
carbonium ions, hypervalently coordinated, gas-phase chemistry, thesis, 15-crown-4, iodo-, with Et, ZN, iodine-zinc exchange, 425
272 18-crown-5, 2-(methoxycarbonyl)-1,3-xylylene-—, cleavage, 347
carbyl sulfates, naphthols, 210; with naphthylalkenes and diphenylhep- crystal structure, (2-iodozincio-1,3-xylylene)-15-crown-4, 425; N,N'-bis-
tene, 247 benzo[a]xanthenylidene-1,2-ethanediamine ZnCl, complex, 377;
carbyl sulfate, from SO; and dienes, 201 calix{4Jarenediquinones, 384; Cu 1-(2-hydroxyethyl)pyrazole complex,
carfentanyl, in medicinal chemistry, 43 309; dicyclopropyl derivs., 635; 2,3-dimethyl-2-butenyl dimethyldithio-
catalysis, 18-crown-5, cleavage by alkal-metal ions, 347; esterase activity carbamate, 273; furopyrroloquinolinecarbonitrile, 549; homoperylene,
of imidazolyl-cyclophanes, 335; hydrolysis of phosphate esters by 584; molecular basket from diphenylglycoluril, 400: molecular cavity
1,10-phenanthroline metallocomplexes, 351; iodonium in glycosida- from diphenylglycoluril, 404; musk compounds, thesis, 39; pyridine
tion by sugar 1,2-thio ortho esters, 507; lipase-catalyzed 6-O-acylation cyclomer, 325; thrombin, 161; 2,4,6-tribenzyl-1,3,5-trithiane, 370
of a-p-glucopyranosides, 567; programmed antibodies, review, 431; CT fluorescence, donor-bridge-acceptor systems from AN-substd. 4-
2-pyridinecarboxylic acid 4-nitrophenyl esters, hydrolysis, 525; vulcan- piperidones, 535
ization by metal compds., thesis, 469 cumulative dienes, sulfonation, 201
catechol, as [2]catenane unit, 429 cyanation, decalinone by Me;SiCN, 259; for methanoretinal, 237
[2]catenanes, contg. benzenediol units, 429 cyanoformate, «-keto esters, synth., review, 471
cavity molecule, from diphenylglycoluril, crystal structure, 404; from cyanohydrins, a-keto esters, synth., review, 471
diphenylglycoluril, 643 cyclic hydrazines, thesis, 515
CCK (cholecystokinin), in medicinal chemistry, review, 95 cyclic phosphates, for ephedrine resolution, 230
CCK-:-A agonists, in medicinal chemistry, review, 95 cyclic voltammetry, binaphthyl salophen crown ether uranyl complex, 595;
CD, see Circular Dichroism calix{4Jarenediquinones, 384
cephalosporins, transformation, in medicinal chemistry, review, 66 #-Cyclization, a-methoxycarbonyl oxycarbenium ions, thesis, 515
cesium ions, 18-crown-5, catalytic cleavage, 347 cycloaddition, 7-substd. 6-demethoxythebaine, 578; SO; + dienes, 201;
charge migration, in 2,5-didecyloxy-1,4-benzoquinone in solid phase, 423 thebaine with carbonyls, 557; of 2,3-[4 + 2]-, dimethylene-2,3-dihydro-
charge-transfer fluorescence, donor-bridge-acceptor systems from AMN- thiophene, 7
substd. 4-piperidones, 535 cycloalkanes, book, 41; methylene-— with SO;, 457
chemists, autobiographies, book, 652 cycloalkylidenecycloalkanes, with SO;, 457
chirality, N,N ‘-bisbenzol a Jxanthenylidene-1,2-ethanediamine, 377; carbo- cyclodextrines, NMR and MM of supramolecules, review, 412
hydrates for chiral products, thesis, 314; cyclophanes with cylindric cyclohexanol, from decompn. of cyclohexyl hydroperoxide, 497
and helical cavity, 421; in enantioselective cleavage of esters by histi- cyclohexanone, from decompn. of cyclohexyl hydroperoxide, 497
dine-contg. tripeptides, 1; in industry, book, 565; 2-pyridinecarboxylic cyclomers, macrocyclic carriers in membranes, review, 317
acid 4-nitrophenyl esters, hydrolysis, 525 cyclopenta-fused hydrocarbons, methylacephenanthrylenes, 22
4-chloroacetanilide, oxidative metabolism by cytochrome P450, 186 cyclopentanthracenes, 287
4-chlorobutanoate, in lipase-catalyzed 6-O-acylation of «-Dp-glucopyrano- cyclopentl hilacephenanthrylene, 255
sides, 567 cyclophanes, imidazolyl-, esterase activity, 335; NMR and MM of
(chloromethyl)dimethylphenylsilane, for destomic acid and 1-de- supramolecules, review, 412; with cylindric and helical cavity, 421
oxynojirimycin, 451 cyclopropanes, influence of substituents on geometry, 635
chromophores, in bacteriorhodopsins, 237, 303 cylomeric pyridines, host molecules, 325
circular dichroism (CD), cyclophanes with cylindric and helical cavity, L-Ccysteine, calixarenes, modification, 407
421 cytochrome P450, oxidative metabolism of 4-chloroacetanilide, 186
CIS, see complexating-induced NMR shift cytostatic activity, in medicinal chemistry, review, 51
Claisen-ene strategy, contraceptive gonatetraenone deriv., 627 Danishefski approach, solid-phase synth. of oligosaccharides, 609
cleavage, 18-crown-5, 347; enantioselective — of esters by histidine-contg. Darzens condensation, a-keto esters, synth., review, 471
tripeptides, 1 decalin, 1-(trimethylsiloxy)—, dehydration to perhydroazulene, 259
CMC, see critical micellar concentration decanucleotides, with (3° — 5’)-O-CH,;-O- linkage, 15
coatings, organic —, vol 1: films, book, 565 demetallation, Cu! 1,10-phenanthroline trefoil knot, kinetics, 427
cobalt, 1-(2-hydroxyethyl)pyrazole complex, 309; proteins, 278 6-demethoxythebaine, with carbonyls, 557
cocaine, in medicinal chemistry, 43 3-deoxy-p-manno-octulosonic acid, review, 471
codeine, 14B-bromo-, in neopine synth., 573 deoxynojirimycin, in medicinal chemistry, review, 82
competition, in Friedel-Crafts sulfocyclization of naphthylalkenes and destomic acid, 451
diphenylheptene, 247 deuterium, in labeled drugs, 191
complexating-induced NMR shift (CIS), supramolecules, review, 412 dialkyldithiocarbamates, Zn —, with haloalkenes, 273
Recueil des Travaux Chimiques des Pays-Bas 112 / 12, December 1993 659
dialkylzince, in regioselective introduction of functional groups in a-diim- Fourier-transform ion-cyclotron resonance (FT-ICR), gas-phase chem-
ines, 618 istry of hypervalently coordinated carbonium ions, thesis, 272
diasteromeric salts, ephedrine, 230 Fourier-transform IR, bacteriorhodopsins, 303; hyphenated — for poly-
1-diaza-2-butanone, intermediate in dopamine receptor, 137 mers, thesis, 39
diazonium salts, for dyes like eriochrome red B and acid alizarin violet N, free radicals, see radicals
552 Friedel-Crafts reaction, a-keto esters, synth., review, 471; sulfocycliza-
(dicyclopropylmethylene)cyclopropane, influence of substituents on ge- tion of naphthylalkenes and diphenylheptene, 247
ometry, 635 B-b-fructopyranosides, alkyl —- and w-halogenoalkyl —, 511
dicylopentaphenanthrenes, 255 p-fructose, for w-halogenoalkyl B-b-fructopyranosides, 511
didemethylmethanoretinals, 237 FT-ICR, see Fourier-transform Ion-Cyclotron Resonance
didentate, 1-(2-hydroxyethyl)pyrazole, 309 FT-IR, see Fourier-transform IR
Diels-Alder reaction, 7-substd. 6-demethoxythebaine, 578; etorphine fullerenes, with ozone, 531, 639
analogs, 113; thebaine with carbonyls, 557 furan, 2-acetyl-, a-keto esters, synth., review, 471
dienes, sulfonation, 201 furopyrroloquinolinecarbonitrile, 549
diethylzinc, iodine-zinc exchange with (2-iodo-1,3-xylylene)-15-crown-4, fused pyrimidines, book, 517
425 G-protein-coupled receptors,, 131; arylpiperidines, conformation, 151
dihydrothiophene, 2,3-dimethylene-2,3-—, [4 + 2] cycloaddition, 7 GAMESS, computer program for calculation on oxidative metabolism of
a-diimines, regioselective introduction of functional groups, 618 4-chloroacetanilide by cytochrome P450, 186
2,3-dimethyl-2-butenyl dimethyldithiocarbamate, crystal structure, 273 gas-phase chemistry, hypervalently coordinated carbonium ions, thesis,
dimethylsulfamoyl, protecting group, 123 272; ions, book, 518; oxychlorination of benzene, 262; unimolecular
1,3,2,4-dioxadithiane tetraoxide, from SO; and dienes, 201 dissociation, thesis, 39
1,7-diphenyl-3-heptene, sulfonation, 247 generalization, protective groups in COSYMA system, CAOS, 503
diphenylalkylamines, modulators of calcium and calmodulin, thesis, 314 glucarate, aluminum calcium complex, !H-, C-, !/O-, ?’AI-NMR, 431
diphenylglycoluril, basket molecule from -—, crystal structure, 400; cavity a-p-glucopyranosides, lipase-catalyzed 6-O-acylation, 567
molecule from —, crystal structure, 404; cavity molecule from —, 643 glutarimide, nucleosides in medicinal chemistry, review, 51
dipolar amphiphiles, 339 glycoluril, diphenyl-, basket molecule from -—, crystal structure, 400;
dipole moment, calix{4jarenes, conformation, 367 cavity molecule from —, crystal structure, 404; cavity molecule from —,
3,4'-diquinolinyl sulfides, 519 643
directing effect, methoxynaphthol sulfonation, 216 glycosidases, inhibition, in medicinal chemistry, review, 82
disaccharide, idose-galactose glycosylation, 611 glycosidation, by sugar 1,2-thio ortho esters, 507
disarmed”, thioglycosyl acceptor, 507 glycosylation, acceptors with L-idose configuration, 611
dissociation, unimolecular —, in gas-phase rections, thesis, 39 glyoxylate thoacetals, a-keto esters, synth., review, 471
[1,4]dithi:i 5,n6-oc’ l]d2iq,ui3no-licne , for 3,4'-diquinolinyl sulfides, 519 gonatetraenone, deriv., 627
dithiocarbamates, Zn dialkyl-, with haloalkenes, 273 guaianolide, skeleton from 1-(trimethylsiloxy)decalin, 259
donor-bridge-acceptor systems, from N-substd. 4-piperidones, 535; the- haloalkenes, with Zn dialkyldithiocarbamates, 273
sis, 40 Haworth synthesis, methylacephenanthrylenes, 22
dopamine re-uptake, inhibited by piperazines, 143 heat transfer, in injection moulding, thesis, 469
dopamine-receptor agonist, a thienyl naphthalenediol, 137 heavy-metal ions, sensors based on ISFETSs, thesis, 40
dressed-micelle model, alkylarenesulfonates, 393 heavy-metal receptors, 2,4,6-tribenzyl-1,3,5-trithiane, 370
drugs, design for K-opioid receptor agonists, 169; design for thrombin, helices, tert-butyl isocyanide oligomers, MM, 33
161; labeling, 191; see medicinal chemistry; research symposium, Hep-G2, in medicinal chemistry, review, 82
Noordwijkerhout, 200 heptaglucoside, having phytoalexin elecitor activity, solid-phase synth.,
dyes, derived from eriochrome red B and acid alizarin violet N, 552 464; solid-phase synth., 464
dynamic NMR, eudesm-11-en-4-ols, 226 3-heptene, 1,7-diphenyl-, sulfonation, 247
electrochemistry, aziridinyiquinones SAR, 174; binaphthyl salophen crown heterocyclic chemistry, progress, book, 315
ether uranyl complex, 595 hexadecyltrialkylammonium bromides, surfactants in cleaving esters
electron paramagnetic resonance (EPR), Cu 1-(2-hydroxyethyl)pyrazole enantioselectively, 1
complex, 309 high-pressure reaction, contraceptive gonatetraenone deriv., 627
electrophilic substitution, homoperylene, 584 histamine, analogs, 123
elimination, base-induced, thesis, 469 histidine, in oligopeptides, coordination with Co, Zn, Cu, 278; in tripep-
enantioselectivity, cleavage of esters by histidine-contg. tripeptides, 1; tides, cleaving esters enantioselectively, 1
2-pyridinecarboxylic acid 4-nitrophenyl esters, hydrolysis, 525 HIV-]I infection, inhibition, in medicinal chemistry, review, 82
enthalpy, see thermodynamics homology model building, human thrombin, 161
enzymes, binaphthyl salophen crown ethers as urease model, 595; in homoperylene, electrophilic substitution, 584
enantioselective cleavage of esters by histidine-contg. tripeptides, 1; host-guest chemistry, AN,N'-a Jbxanithensvylbideene-n1,2z-etohanledi a-
inhibition in medicinal chemistry, review, 51; lipase-catalyzed 6-0O- mine, 377; binaphthyl metallomacrocycles, 358; binaphthyl salophen
acylation of a-b-glucopyranosides, 567; metallomacrocycles as mod- crown ether uranyl complex, 595; book, 651; calixarenes, modified
els, thesis, 470; programmed antibodies, review, 431; 2-pyridine- with L-cysteine, 407; for carbazole and bipyridine cyclomers, 330;
carboxylic acid 4-nitrophenyl esters, hydrolysis, 525 cyclophanes with cylindric and helical cavity, 421; imidazolylcyclo-
epoxides, in neopine synth., 573 phanes, esterase activity, 335; macrocyclic carriers in membranes,
EPR, see electron paramagnetic resonance review, 317; molecular basket from diphenylglycoluril, 400; molecular
eriochrome red B, like dyes, 552 cavity from diphenylglycoluril, 404, 643; NMR, review, 412; pyridine
ester cleavage, enantioselective —, by histidine-contg. tripeptides, 1 cyclomers as host molecule, 325; 317-430
esterase activity, imidazolylcyclophanes, 335 S-HT, see serotonin
esterification, in lipase-catalyzed 6-O-acylation of a-b-glucopyranosides, human thrombin, homology model building, 161
567 a-hydrazino acids, thesis, 515
ethenoisomorphinans, 7-substd. 6-demethoxythebaine, 578; etorphine cis-hydroazulene sesquiterpenes, thesis, 314
analogs, 113; thebaine with carbonyls, 557 hydrogen peroxide, with penicillin G, 462
ethenomorphinans, 7-substd. 6-demethoxythebaine, 578 hydrolase activity, imidazolylcyclophanes, 335
etorphine, analog from thebaine with carbonyls, 557; analogs, 113 hydrolysis, binaphthyl salophen crown ether uranyl complex, 595; phos-
eudesm-11-en-4-ols, conformation, 226; thesis, 273 phate esters, catalysis by 1,10-phenanthroline metallocomplexes, 351;
ferrodoxines, synthetic analogs, thesis, 469 2-pyridinecarboxylic acid 4-nitrophenyl esters, 525
ferromagnetism, anti-, Cu 1-(2-hydroxyethyl)pyrazole complex, 309 hydroperoxide, cyclohexyl-, decompn., 497
films, organic coatings, vol 1, book, 565 hydrophobicity, calixarenes, modified with L-cysteine, 407
fluorescence, calixarenes, modified with L-cysteine, 407; donor-bridge- 1-(2-hydroxyethyl)pyrazole, coordination with Co, Ni, Cu, Zn, 309
acceptor systems from N-substd. 4-piperidones, 535 5-hydroxytryptamine, see serotonin
5-fluorouracil, prodrug in medicinal chemistry, review, 51 hyperchromicity, UV —, decanucleotides with (3° — 5”)-O-CH,;-O-linkage,
force-field calculations, MM on fert-butyl isocyanide oligomers, 33; NMR 15
and MM of supramolecules, review, 412 hypervalency, carbonium ions, gas-phase chemistry, thesis, 272
formate, ethyl cyano-—, a-keto esters, synth., review, 471 hyphenated FT-IR, polymers, thesis, 39
formylation, homoperylene, 584 idose-galactose disaccharide, glycosylation, 611
660 Subject Index
L-iduronic acid, glycosylation of acceptors with L-idose configuration, 611 metal binding, to hosts, 330
imidazoles, («@—-aminoalkyl)-, 123 metal ions, 18-crown-5, catalytic cleavage, 347
imidazolylcyclophanes, esterase activity, 335 metal receptors, 2,4,6-tribenzyl-1,3,5-trithiane, 370
12-iminoba]e xannzthoenle) , ethanediylbis(, ZnCl, complex, crystal struc- metal-catalyzed sulfur vulcanization, thesis, 469
ture, 377 metallo-cleft, N, N '-bisbenzol a Jxanthenylidene-1,2-ethanediamine, 377
iminomethylenes), poly(—, MM, 33 metallocomplexes, of 1,10-phenanthroline, catalytically hydrolyzing phos-
immunoglobulines, programmed antibodies, review, 431 phate esters, 351
industrial manufacture, chiral compounds, book, 565 metalloenzyme model, 2-pyridinecarboxylic acid 4-nitrophenyl esters, hy-
injection moulding, heat transfer, thesis, 469 drolysis, 525
inorganic chemicals handbook, book, 517 metallomacrocycles, binaphthyl salophen crown ethers as urease model,
interfacial tension, alkylarenesulfonate micellization, 393 595; binaphthyl -, complexation, 358; enzyme models, thesis, 470
inulin, for «w-halogenoalkyl B-D-fructopyranosides, 511; from chicory metallovesicular assemblies, in hydrolysis of 4-nitrophenyl esters, 525
roots, thesis, 40 methacrylates, a-keto esters, synth., review, 471
iodine, Zn exchange in (2-iodo-1,3-xylylene)-15-crown-4 + Et,Zn, 425 methanesulfonates, with naphthols, 210
iodonium-promoted glycosidation, by sugar 1,2-thio ortho esters, 507 methanoretinals, 237
ions, chemistry in gas-phase, book, 518 1,6-methano[10]annulene, electrophilic substitution, 584
IR, bacteriorhodopsins, 303; hyphenated FT-IR on polymers, thesis, 39; a-methoxycarbonyl oxycarbenium ions, 7-cyclization, thesis, 515
nitroaceanthrylenes and -aceanthrenes, 287 methoxycarbonyl)-1,3-xylylene-18-crown-5, cleavage, 347
ISFETSs, for heavy-metal-ion sensors, thesis, 40 methoxymethoxy group, protecting OH in 7-substd. 6-demethoxythebaine,
isocyanide oligomers, tert-butyl-, MM, 33 578
isomerization, V,N ‘-bisbenzol a Jxanthenylidene-1,2-ethanediamine, syn-— methoxynaphthol, sulfonation, 216
anti, 377 methylacephenanthrylenes, 22
isotope effect, labeled drugs, 191 methylenecycloalkanes, with SO;, 457
K-opioid receptor agonists, 169 methylenedioxy linkage, in decanucleotides, 15
KDO (3-dexoxy-p-manno-2-octulosonic acid), review, 471 5-methyl, influence in bacteriorhodopsin, 303
a-keto esters, review, 471 mianserin, labeling, 191
kinetics, benzene gas-phase oxychlorination, 262; C, and C with ozone, micelles, alkylarenesulfonates, thermodynamics, 393; in hydrolysis of
531; Co, etc., with ozone, 639; 18-crown-5, cleavage by alkal-metal phosphate esters by 1,10-phenanthroline metallocomplexes, 351;
ions, 347; Cu! 1,10-phenanthroline trefoil knot, demetallation, 427; platelike, 339; solutions in enantioselective cleavage of esters by
cyclohexy!l hydroperoxide decompn., 497; in enantioselective cleavage histidine-contg. tripeptides, 1
of esters by histidine-contg. tripeptides, 1; hydrolysis of phosphate mifepristone, analog, 107
esters by 1,10-phenanthroline metallocomplexes, 351; 2-pyridine- migration of 4-substituent, oxidative metabolism of 4-chloroacetanilide by
carboxylic acid 4-nitrophenyl esters, hydrolysis, 525 cytochrome P450, 186
knot, trefoil, Cu! 1,10-phenanthroline complex, crystal structure, 427 mirtazepin, labeling, 191
labeling, bacteriorhodopsins and bovine rhodopsins, thesis, 470; drugs, MM, see molecular mechanics
191 MNDO), see molecular mechanics
lactones, sesquiterpene — from chicory roots, thesis, 40 molecular cavity, see host-guest chemistry
lamellar lyophases, 339 molecular cleft, see host-guest chemistry
lipase, catalyzing 6-O-acylation of a-b-glucopyranosides, 567 molecular design, in medicinal chemistry, 43
lipophilic heavy-metal receptors, 2,4,6-tribenzyl-1,3,5-trithiane, 370 molecular dynamics, thrombin, 161
liquid membranes, macrocyclic carriers in —, review, 317 molecular mechanics (MM), arylpiperidines, conformation, 151; bi-
lithiation, imidazole, 123 naphthyl metallomacrocycles, 358; binaphthyl salophen crown ether
lithium ions, 18-crown-5, catalytic cleavage, 347 uranyl complex, 595; calix{4Jarenes, 367; cyclophanes with cylindric
local anesthetics, in medicinal chemistry, 43 and helical cavity, 421; eudesm-11-en-4-ols, 226; tert-butylisocyanide
locked chromophores, in bacteriorhodopsins, 237 oligomers, 33; K-opioid receptor agonists, 169; serotonin receptor
longe-range donor-acceptor interaction, thesis, 40 subclasses, 131; supramolecules, review, 412
lyophases, lamellar, 339 molecular modeling, see molecular mechanics
macrocycles, binaphthyl metallo-, complexation, 358; calix{4Jaren- molecular recognition, calixarenes, modified with L-cysteine, 407
ediquinones, 384; carriers in membranes, review, 317; cyclophanes molecular-orbital package (MOPAC), arylpiperidines, conformation, 151;
with cylindric and helical cavity, 421; metallo- as enzyme models, K-opioid receptor agonists, 169
thesis, 470; metallo-, binaphthyl salophen crown ethers as urease monoamine re-uptake, inhibited by piperazines, 143
model, 595; pyridine cyclomers as host molecule, 325; receptors in MOPAC, see molecular-orbital package
membrane transport, thesis, 40; receptors in membranes, review, 317 morphinan-5,8-dienes, thebaine with carbonyls, 557
macromolecular science, book, 316 morphine, K-opioid receptor agonists, 169
magnesium chloride, (dimethylphenyl)silyl-, for destomic acid and 1-de- morphinomimetics, in medicinal chemistry, 43
oxynojirimycin, 451 moulding, injection —, heat transfer, thesis, 469
magnetic susceptibility, Cu 1-(2-hydroxyethyl)pyrazole complex, 309 MS, bacteriorhodopsins, 237, 303; dicylopentaphenanthrenes, 255; in bi-
malonates, a-keto esters, synth., review, 471 ology, book, 236; methylacephenanthrylenes, 22; nitroaceanthrylenes
manganese(IIl), salen complex, crystal structure, 404; tetraarylpor- and -aceanthrenes, 287
phyrins, catalyst in decompn. of cyclohexyl peroxide, 497 Müller-Rôscheisen reaction, for pyridine cyclomers, 325
mannarate, aluminum calcium complex, 1H, SC. lO., 7’AI-NMR, 431 musk compounds, X-ray, thesis, 39
mass spectrometry, see MS N-0437, dopamine-receptor agonist, 137
mechanism, benzene gas-phase oxychlorination, 262; cyclohexyl hydroper- NANA, review, 471
oxide decompn., 497; Friedel-Crafts sulfocyclization of naphth- naphthalenediol, thienyl-, dopamine-receptor agonist, 137
ylalkenes and diphenylheptene, 247; methoxynaphthol sulfonation, naphthalene, retinals, 237; sultone, 216
216; naphthols, sulfonation, 210; organic chemistry, book, 468; radical 1-naphthol, sulfonation, 210,216
—, oxidative metabolism of 4-chloroacetanilide by cytochrome P450, 2-naphthol, sulfonation, 210,216
186; SO+ d;iene s, 201; with SO; with methylenecycloalkanes and w-(1-naphthyl)-n-alkenes, sulfonation, 247
cycloalkylidenecycloaälkanes, 457 natural products, book, 652
medicinal chemistry, (w—-aminoalkyl)imidazoles, 123; aza sugars, review, NBS, see succinimide, N-bromo-
82; CCK-A agonists, review, 95; dopamine-receptor agonist, 137, 137; neopine, 573
etorphine analogs, 113; human thrombin, 161; K-opioid receptor ago- networks, biomedical polyurethane -—, thesis, 272
nists, 169; labeled drugs, 191; mifepristone analog, 107; in nucleo- neuSAC, review, 471
sides, review, 51; penicillin and cephalosporin transformation, review, neuraminic acid, V-acetyl-, review, 471
66; piperazines inhibiting amine re-uptake, 143; review, 43; serotonin neuroleptic action, in medicinal chemistry, 43
(ant)agonists, 126; serotonin receptor subclasses, 131; special issue, nickel, conductors based on Ni(C;,S), and Ni(C;,Ses);, thesis, 314; 1-(2-
43-199 hydroxyethyl)pyrazole complex, 309; salen complex, crystal structure,
membrane chemistry, book, 315 404
membrane transport, macrocyclic carriers in —, review, 317; macrocyclic nitration, homoperylene, 584
receptors, thesis, 40 nitroaceanthrenes, 287
mesogenic amphiphiles, 339 nitroaceanthrylenes, 287
metabolism, oxidative —, 4-chloroacetanilide, by cytochrome P450, 186 nitroacetates, «-keto esters, synth., review, 471
Recueil des Travaux Chimiques des Pays-Bas 112 / 12, December 1993
4-nitrophenyl ester cleavage, enantioselective —, by histidine-contg. phosphorus, organo-, book, 271
tripeptides, 1 photophysics, donor-bridge-acceptor systems from N-substd. 4-piperi-
NMR, book, 651; supramolecules, NOESs, review, 412 dones, 535
NMR, 'H, aluminum calcium aldarate, 431; bacteriorhodopsins, 237, 303; phytoalexin elecitor activity, heptaglucoside, 464
calix{4Jarenediquinones, 384; decanucleotides with (3’ — 5')-O-CH;- picolinic acid, hydrolysis of 4-nitrophenyl esters, 525
O- linkage, 1D- en 2D-NMR, 15; dicylopentaphenanthrenes, 255; piperazines, aryl-, conformation, 151; inhibiting amine re-uptake, 143
etorphine analogs, 113; eudesm-11-en-4-ols, 226; methylacephenan- piperidines, aryl-, conformation, 151
thrylenes, 22; molecular basket from diphenylglycoluril, 400; naph- 4-piperidones, V-substd. —, donor-bridge-acceptor systems, 535
thols, sulfonation, 210; neopine, 573; nitroaceanthrylenes and platelike micelles, 339
-aceanthrenes, 287; with SO; with methylenecycloalkanes and cy- PM3 geometry, 131
cloalkylidenecycloalkanes, 457; thebaine with carbonyls, 557 POCH3, see phosphorus oxychloride
NMR, “H -, labeled drugs, 191
Poisson-Boltzmann model, micellar properties, 393
NMR, C, aluminum calcium aldarate, 431; bacteriorhodopsins, 237, 303; poly(iminomethylenes), MM, 33
etorphine analogs, 113; neopine, 573; nitroaceanthrylenes and polycyclic aromatic hydrocarbons (PAHSs), dicylopentaphenanthrenes,
-aceanthrenes, 287; thebaine with carbonyls, 557 255; methylacephenanthrylenes, 22; nitroaceanthrylenes and
NMR, °C, aluminum calcium aldarate, 431: bacteriorhodopsins, 237, 303; -aceanthrenes, 287
etorphine analogs, 113; neopine, 573; nitroaceanthrylenes and polymer-supported synthesis, see solid-phase synth.
-aceanthrenes, 287; thebaine with carbonyls, 557 polymers, book, 316; hyphenated FT-IR, thesis, 39
NMR, !’O, aluminum calcium aldarate, 431 polyurethane, biomedical — networks, thesis, 272
NMR, ?’Al, aluminum calcium aldarate, 431 potassium ions, 18-crown-5, catalytic cleavage, 347
NOE, see NMR PR-TRMC (pulse-radiolysis time-resolved microwave conductivity), in
nojirimycin, 1-deoxy-, 451 2,5-didecyloxy-1,4-benzoquinone in solid phase, 423
19-norsteroids, mifepristone analog, 107 programmed antibodies, as tailor-made catalysts, review, 431
nucleophilic cleavage of S,2 type (BAL2), 18-crown-5, 347 protection, OH in 7-substd. 6-demethoxythebaine by methoxymethoxy,
nucleosides, in medicinal chemistry, review, 51 578
nucleotides, deca-, with (3° — 5’)-O-CH,;-O- linkage, 15 protective groups, in COSYMA system, CAOS, 503
3-octulosonic acid, 3-deoxy-p-manno- (KDO), review, 471 proteins, see also peptides; thrombin, 161
oligomers, tert-butyl isocyanides, MM, 33 protein-protein interaction, in medicinal chemistry, 43
oligonucleotides, with (3 — 5')-O-CH,;-O- linkage, 15 proton pump, bacteriorhodopsins, 237, 303
oligopeptides, L-histidyl-containing —, coordination with Co, Zn, Cu, 278 PTAT, dopamine-receptor agonist, 137
oligopyridine rings, host molecules, 325 pulse-radiolysis time-resolved microwave conductivity (PR-TRMC), in
oligosaccharides, solid-phase synth., 609 2,5-didecyloxy-1,4-benzoquinone in solid phase, 423
omeprazole, in medicinal chemistry, 43 pyrazoles, cyclomeric — as host, 330; 1-(2-hydroxyethyl)-, coordination
K-opioid receptor agonists, 169 with Co, Ni, Cu, Zn, 309
opium alkaloids, 7-substd. 6-demethoxythebaine, 578; etorphine analogs, 2-pyridinecarboxylic acid, hydrolysis of 4-nitrophenvyl esters, 525
113; neopine, 573; thebaine with carbonylis, 557 [2n](2,6)pyridinophanes, host molecules, 325
opsin shift, in bacteriorhodopsins, 237, 303 pyrimidines, fused —, book, 517
organic chemistry, book, 41; reactions, mechanism, structure (book), 468; pyrolysis, see thermochemistry
reagents, book, 468 pyrroles, book, 649
organic coatings, vol 1: films, book, 565 pyrrolidine nucleosides, in medicinal chemistry, review, 51
organic reactions, tandem —, book, 518; vol. 41, book, 516 pyrrolidinones, from regioselective introduction of functional groups in
organic synthesis, vol. 70, book, 652 a-diimines, 618
organometallic chemistry, book, 315; transition metals, book, 467 3-pyrrolin-2-one, (R)-1-acetyl-5-isopropoxy-, thesis, 515
organophosphorus, book, 271 pyruvates, «-keto esters, synth., review, 471
organozinc, (2-iodozincio-1,3-xylylene)-15-crown-4, 425 QSAR (quantitative structure-activity relationship), see SAR
ortho esters, in neopine synth., 573; sugar 1,2-thio —, 507 Qua/n CHtARaMm , thrombin, 161
oxalates, a-keto esters, synth., review, 471 quantitative structure-activity relationship (QSAR), see SAR
1,2-oxathietane dioxide, from SO; and dienes, 201 quantum chemistry, see molecular mechanics
oxidative metabolism, 4-chloroacetanilide, by cytochrome P450, 186 o-quinodimethane, 2,3-dimethylene-2,3-dihydrothiophene analog, 7
a-0x0 esters, review, 471 quinolines, 4-alkoxy-3-(alkylthio)-, 519
oxycarbenium ions, a-methoxycarbonyl —, 7-cyclization, thesis, 515 quinones, aziridinyl-, SAR, 174; calix{4Jarenes, 384
oxychlorination, benzene, 262 radiation-induced conductivity, in 2,5-didecyloxy-1,4-benzoquinone in
ozone, With Co and Cy, 531; with Co, etc., 639 solid phase, 423
PAHSs, see polycyclic aromatic hydrocarbons radical ionic systems, condensed phases, book, 42
palladium, conductors based on Pd(C;S;); and Pd(C;Se;);, thesis, 314 radicals, in benzene gas-phase oxychlorination, 262; oxidative metabolism
Pedersen memorial issue, book, 516 of 4-chloroacetanilide by cytochrome P450, 186
penicillins, transformation, in medicinal chemistry, review, 66; — G, with radiolysis, labeled drugs, 191
peroxy compds., 462 rational design, resolving agents, 230
1,3-pentadiene, sulfonation, 201 reaction mechanism, see mechanism
pentapeptides, L-histidyl-containing —, coordination with Co, Zn, Cu, 278 reactions, organic chemistry, book, 468
peptides, histidine-contg. tri-, cleaving esters enantioselectively, 1; L- reagents, for organic synth., book, 468
histidyl-containing —, coordination with Co, Zn, Cu, 278; topology, rearrangement, allylic —, in neopine synth., 573; 1-(trimethylsiloxy)decalin
CCK:-A agonists, in medicinal chemistry, review, 95 to perhydroazulene, 259
peptidomimetics, CCK-A agonists, in medicinal chemistry, review, 95 receptors, affinity for serotonins, 131; affinity of a thienyl naphthalene-
perception, protective groups in COSYMA system, CAOS, 503 diol, 137; arylpiperidines, model, 151; K-opioid agonists, 169
peroxyoctanoic aicd, with penicillin G, 462 redox, calix{4Jarenediquinones, 384
perylene, electrophilic substitution, 584 reductive cyanation, for methanoretinal, 237
pethidine, in medicinal chemistry, 43 regioselective introduction, functional groups in a-diimines, 618
Ph.D. theses, see theses reserpine, dopamine-receptor agonist, 137
phase diagrams, dipolar amphiphiles, 339 resolution, ephedrine, rational design, 230
phenanthrenes, dicylopenta-—, 255 retinals, labeling, thesis, 470; 237
1,10-phenanthroline, Cu! trefoil knot, crystal structure, 427; functional- retinal, 5-bromo-5-demethyl-, 303
ized, in hydrolysis of 4-nitrophenyl esters, 525; metallocomplexes reviews, aza sugars, in medicinal chemistry, 82; CCK-A agonists, in
catalytically hydrolyzing phosphate esters, 351 medicinal chemistry, 95; a-keto esters, synth., 471; macrocyclic carri-
phenylalanine ester, enantioselective cleavage by histidine-contg. tripep- ers in supported liquid membranes, 317; medicinal chemistry, 43;
tides, 1 NMR and MM in supramolecules, 420; nucleosides in medicinal
phosphate esters, catalytically hydrolyzed by phenanthroline metallocom- chemistry, 51; penicillin and cephalosporin transformation, in medici-
plexes, 351; cyclic — for ephedrine resolution, 230 nal chemistry, 66; programmed antibodies as tailor-made catalysts,
phosphonates, a-keto esters, synth., review, 471 431
phosphoranes, a-keto esters, synth., review, 471 rhodium acetate, catalyzing cyclization to a tetralone, 137
phosphorus oxychloride, dehydrating 1-(trimethylsiloxy)decalin to perhy- rhodopsins, bacterio-, 237; 5-bacterio-, methyl influence, 303; labeling,
droazulene, 259 thesis, 470
662 Subject Index
rigidity, chromophores in bacteriorhodopsins, 237; dipolar amphiphiles, syn-anti isomerization, /V,N'-a Jbxanithesnylbideene-n1,2z-etohanledi a-
339 mine, 377
ring enlargement, in medicinal chemistry, review, 66 tandem Claisen-ene strategy, contraceptive gonatetraenone deriv., 627
ring formation, furopyrroloquinolinecarbonitrile, 549 tandem organic reactions, book, 518
Rodd’s chemistry of carbon compounds, 2nd suppl., book, 650 template structures, thrombin, 161
saccharides, see carbohydrates tetraarylporphyrins, Mn!!!, catalyst in decompn. of cyclohexyl peroxide,
salen, metal complexes, crystal structure, 404 497
salophen, binaphthyl —, crown ethers, 595 tetrahydrofurano formation, furopyrroloquinolinecarbonitrile, 549
SAR, see structure-activity relationship tetralone, intermediate in dopamine receptor, 137
SCE, see self-consistent field tetrapyrroles, biosynth., book, 271
self-assembly, 2,5-didecyloxy-1,4-benzoquinone in solid phase, 423; 1,2- thallium(TIL), nitrate, oxidizing dialkoxycalix{4Jarenes, 384
bismetallo-clefts, benzola]xanthenylidene-1,2-ethanediamine, 377; thebaines. 7-substd. 6-demethoxy-, 578; etorphine analogs, 113, 113; with
[2Jcatenanes contg. catechol units, 429 carbonyls, 557
self-consistent field (SCF) calculation, oxidative metabolism of 4-chloro- thermochemistry, benzene gas-phase oxychlorination, 262
acetanilide by cytochrome P450, 186 thermodynamics, micellization of alkylarenesulfonates, 393
semi-empirical calculation, arylpiperidines, conformation, 151 theses, (R)-1-acetyl-5-isopropoxy-3-pyrrolin-2-one, 515; bacteriorho-
sequence alignment, thrombin, 161 dopsins and bovine rhodopsins, labeling, 470; base-induced elimi-
serotonin, (ant)agonists, 126; receptor subclasses, 131 nation reactions, 469; binary fluid mixtures, 272; biomedical
sesquiterpenes, cis-hydroazulene -—, thesis, 314; lactones from chicory polyurethane networks, 272; biosensors, third generation amperomet-
roots, thesis, 40 ric, 39; carbohydrates for chiral products, 314; conductors based on
sialyltransferases, thesis, 470 M(C;3S:); and M(C;Sei);, 314; cyclic hydrazines and a-hydrazino
silane, (1,2-diethoxy-1,2-ethanediyl)bis(trimethyl-, «-keto esters, synth., acids via N-acylhydrazonium ions, 515; -cyclizations of a-methoxy-
review, 471 carbonyl oxycarbenium ions; oxacyclic carboxylic esters, 515; dipheny-
silane, (chloromethyl)dimethylphenyli-, for destomic acid and 1-de- lalkylamines: modulators of calcium and calmodulin, 314; donor-
oxynojirimycin, 451 bridge-acceptor systems for detection of longe-range donor-acceptor
silver, 2,4,6-tribenzyl-1,3,5-trithiane complex, 370 interaction, 40; eudesm-11-en-ols, 273; gas-phase chemistry of hyper-
silyl, tert-butyldimethyl-, protecting group, 123 valently coordinated carbonium ions, 272; gas-phase rections, uni-
silyloxy)-1,2-diethoxyethane, 1,2-bis(trimethyl-, a-keto esters, synth., re- molecular dissociation, 39; heat transfer in injection moulding, 469;
view, 471 heavy-metal ions, sensors based on ISFETS, 40; cis-hydroazulene
simplified-perturbed-hard-chain equation, on binary fluid mixtures, the- sesquiterpenes, 314; intramolecular coordination in WŸ! alkylidene
sis, 272 chemistry, 470; macrocyclic receptors in membrane transport, 40;
SKF 38393, dopamine-receptor agonist, 137 metal-catalyzed sulfur vulcanization, 469; metallomacrocycles as en-
S\2 cleavage, 18-crown-5, 347 zyme models, 470; musk compounds, X-ray, 39; polymers, hyphenated
SO;, see sulfur trioxide FT-IR, 39; sesquiterpene lactones and inulin from chicory roots, 40;
sodium ions, 18-crown-5, catalytic cleavage, 347 sialvitransferases, 470; synthetic analogs for ferrodoxines, 469
solid-phase synthesis, heptaglucoside, 464; oligosaccharides, 609 thiacrown ethers, 370
solvatochromism, donor-bridge-acceptor systems from V-substd. 4- thiazole, 2-acetyl-, «-keto esters, synth., review, 471
piperidones, 535 thienyl naphthalenediol, dopamine-receptor agonist, 137
solvent binding, by cyclomeric pyridines, 325 1,2-thio ortho esters, sugar —, 507
sorbitol, for chiral products, thesis, 314 thiophene, 2,3-dimethylene-2,3-dihydro-, [4 + 2] cycloaddition, 7
SPHC equation, on binary fluid mixtures, thesis, 272 thiophenes, book, 649
spin distribution calculation, oxidative metabolism of 4-chloroacetanilide thioquinanthrene, for 3,4'-diquinolinyl sulfides, 519
by cytochrome P450, 186 thiuram sulfides, 273
spiperone, dopamine-receptor agonist, 137 thrombin, human -—, homology model building, 161
spirosultones, from methylenecycloalkanes and cycloalkylidenecycloalka- transesterification, in lipase-catalyzed 6-O-acylation of a-b-glucopyrano-
nes, 457 sides, 567
stereochemistry, book, 42 transferases, sialyl-, thesis, 470
stereoselectivity, 2-pyridinecarboxylic acid 4-nitrophenyl esters, hydroly- transition metals, organometallic chemistry, book, 467
sis, 525 transport, macrocyclic carriers in membranes, review, 317
steroids, brassino-, book, 467; contraceptive gonatetraenone deriv., 627; trefoil knot, Cu! 1,10-phenanthroline complex, crystal structure, 427
mifepristone analog, 107, 107 triaza[3.3.3]paracyclophanes, with cylindric and helical cavity, 421
structure, organic chemistry, book, 468 2,4,6-tribenzyl-1,3,5-trithiane, crystal structure, 370
structure-activity relationship (SAR), aziridinylquinones, 174; CCK-A trifluoroacetic acid, transforming a tetralone, 137
agonists, in medicinal chemistry, review, 95; serotonin (ant)agonists, 1-(trimethylsiloxy)decalin, dehydration to perhydroazulene, 259
126 tripeptides, see peptides
substituent effect, in ephedrine resolution, 230 1,3,5-trithiane, 2,4,6-tribenzyl-, crystal structure, 370
succinimide, N-bromo-— (NBS), homoperylene, bromination, 584 tritium, in labeled drugs, *H-NMR, 191
sucrose, for w-halogenoalkyl B-b-fructopyranosides, 511 tropacaine, in medicinal chemistry, 43
sugar 1,2-thio ortho esters, 507 tryptamine, 5-hydroxy-, see serotonin
sugar acids, aluminum calcium complex, !H-, C-, !/O-, ?’AI-NMR, 431 tryptamines, receptor subclasses, 131
sugars, see carbohydrates tumor inhibition, mifepristone analog, 107
sulfanilamide, in medicinal chemistry, 43 tungsten(VI), in alkylidene chemistry, thesis, 470
sulfonates, micellization, thermodynamics, 393 turnover catalysis, esterase activity of imidazolylcyclophanes, 335
sulfonation, dienes, 201; homoperylene, 584; methoxynaphthols, 216; U 50 488, K:-opioid receptor agonists, 169
methylenecycloalkanes and cycloalkylidenecycloalkanes, 457; 1- and unimolecular dissociation, in gas-phase rections, thesis, 39
2-naphthols, 210; naphthylalkenes and diphenylheptene, 247 uranyl, binaphthyl metallomacrocycles, 358; binaphthyl salophen crown
sulfur trioxide (SO), withdienes, 201; with methoxynaphthols, 216; with ether complex, 595
methylenecycloalkanes and cycloalkylidenecycloalkanes, 457; with 1- urease, binaphthyl salophen crown ethers as enzyme model, 595
and 2-naphthols, 210; with naphthylalkenes and diphenylheptene, 247 urea, binaphthyl metallomacrocycles, complex, 358; complexation by bi-
sulfur vulcanization, metal-catalyzed —, thesis, 469 naphthyl salophen crown ether uranyl complex, 595
sulfur-35, in labeled drugs, 191 UV, bacteriorhodopsins, 237, 303; Cu 1-(2-hydroxyethyl)pyrazole complex,
sulfur-carbon-sulfur bond, alkylation, 370 309; decanucleotides with (3 — 5')-O-CH,;-O- linkage, hyperchromic-
B-sultones, from dienes, 201; with naphthylalkenes and diphenylheptene, ity, 15; dicylopentaphenanthrenes, 255; methylacephenanthrylenes, 22;
247 nitroaceanthrylenes and -aceanthrenes, 287
supported liquid membranes, macrocyclic carriers in —, review, 317 vesicular assemblies, in hydrolysis of 4-nitrophenyl esters, 525
supramolecular chemistry, see host-guest chemistry; book, 651; Pedersen viscosity, dipolar amphiphiles, 339
memorial issue, book, 516; 317-430 voltammetry, cyclic —, binaphthyl salophen crown ether uranyl complex,
surface tension, dipolar amphiphiles, 339 595; calix{4Jarenediquinones, 384
surfactants, hexadecyltrialkylammonium bromides in cleaving esters vulcanization, metal-catalyzed, thesis, 469
enantioselectively, 1 water activity, in lipase-catalyzed 6-O-acylation of a«-b-glucopyranosides,
synthesis design, see CAOS 567