Quick Cognitive Screening for Clinicians Mini Mental, Clock Drawing and Other Brief Tests Quick Cognitive Screening for Clinicians Mini Mental, Clock Drawing and Other Brief Tests Kenneth I Shulman MD SM FRCPsych FRCPC Professor and Richard Lewar Chair Department of Psychiatry University of Toronto Sunnybrook and Women’s College Health Sciences Centre Toronto, Ontario, Canada Anthony Feinstein MPhil PhD FRCPC Professor Department of Psychiatry University of Toronto Sunnybrook and Women’s College Health Sciences Centre Toronto, Ontario, Canada LONDON AND NEW YORK © 2003 Martin Dunitz, an imprint of the Taylor & Francis Group First published in the United Kingdom in 2003 by Martin Dunitz, an imprint of the Taylor and Francis Group, 11 New Fetter Lane, London EC4P 4EE Tel.: +44 (0) 20 7583 9855 Fax.: +44 (0) 20 7842 2298 E-mail: [email protected] Website: http://www.dunitz.co.uk This edition published in the Taylor & Francis e-Library, 2005. “To purchase your own copy of this or any of Taylor & Francis or Routledge’s collection of thousands of eBooks please go to www.eBookstore.tandf.co.uk.” All rights reserved. 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Contents Preface vi Acknowledgements and Dedication vii Chapter 1 Introduction to cognitive screening 1 Chapter 2 Premorbid intellectual functioning 11 Chapter 3 Mini Mental State Examination 26 Chapter 4 The Clock Drawing Test 40 Chapter 5 Tests of frontal lobe function 76 Chapter 6 Short cognitive screening tests and batteries 98 Chapter 7 Informant questionnaires 121 Chapter 8 Neuroimaging correlates of cognitive 136 dysfunction Chapter 9 Clinical vignettes 157 Index 171 Preface This collaboration on cognitive screening brings together two rapidly growing and overlapping fields, namely geriatric psychiatry and neuro-psychiatry. As colleagues in the same department, we came to realize the importance of sharing our expertise and experience of assessing and treating a wide range of central nervous system (CNS) disorders. The fields of psychiatry, geriatrics, neurology, neuropsychology and primary care all share a role and vested interest in the early identification of brain disorders as well as having the capacity to monitor cognitive changes over time. The book focuses on the brief or ‘quick’ cognitive screening instruments. Inevitably, there is a selection bias on the part of the authors in terms of which instruments we chose to review and their relative emphasis. However, we did strive for objectivity in reviewing those instruments most widely used and studied. We also felt that a chapter devoted to frontal lobe tests was necessary, given the importance of this brain region in modulating behavior and cognition. In this book, we summarize the current state of knowledge related to the development of cognitive screening instruments. Hopefully, readers will find the book of academic interest and practical value in their daily clinical work. Kenneth I Shulman Anthony Feinstein Acknowledgements We gratefully acknowledge the help of Dilshad Ratansi in the preparation of the manuscript and Abigail Griffin for her careful editing of the text. Dedication We dedicate this book to our families: Karen, Pippa, Saul and Clara Rhona, Rayzie and Tamara Chapter 1 Introduction to cognitive screening Why cognitive screening? With a rapidly growing elderly population comes the ‘demographic imperative’ that neuropsychiatric disorders will become one of the major clinical and public health challenges of the next generation. The dementias and neuropsychiatric disorders in this population, as well as in younger patients, represents a challenge for which we are still largely unprepared. While many of these conditions are not reversible, secondary and tertiary prevention are realistic and important goals for health-care systems around the world. Prevention involves early diagnosis and treatment, but also disability limitation and the prevention of complications resulting from those disorders (Ganguli, 1997). Ganguli rightly makes the point that ‘No cognitive screening measure is an Alzheimer’s test;. While non-professionals can generally perform screening, those who test positive need to be targeted for more skilled and detailed assessments. Although screening represents only the first step in a process of assessment and ‘work-up’, it still offers the best opportunity for secondary prevention (Ganguli, 1997). Early detection carries with it a number of important potential benefits from a clinical as well as a societal perspective: 1.The early diagnosis of a neuropsychiatric or dementing disorder offers the opportunity to provide an explanation to patients and families regarding changes in cognition, functioning, behavior or mood. 2.The establishment of a firm diagnosis allows for planning of important issues for the patient and family. This includes the preparation of Powers of Attorney for property and personal