Table Of Content

The Quarterly Journal of Medicine Edited by JSTEWART CAMERON (Senior Editor), A BRECKENRIDGE, DP DE BONO, CRW EDWARDS, CD MARSDEN, G NEALE, R SMITH, MF SUDLOW, HC THOMAS, DA WARRELL, PJ WATKINS, DG WILLIAMS, FH EPSTEIN (American Editor), JM HOLT (Executive Editor) New Series, Volumes 78-81, 1991 OXFORD UNIVERSITY PRESS Contents VOLUME 78 No 285, January 1991 Post-marketing Drug Surveillance - How Far Have We Got? DG McDevitt and TM MacDonald Epidemiology of Inflammatory Bowel Disease V Jayanthi, CSJ Probert and JF Mayberry Post-cimetidine Surveillance for up to Ten Years: Incidence of Carcinoma of the Stomach and Oesophagus DG Colin-Jones, MJS Langman, DH Lawson, RFA Logan, KR Paterson and MP Vessey Breathing During Sleep in Patients with Myotonic Dystrophy and Non-myotonic Respira- tory Muscle Weakness JJ Gilmartin, BG Cooper, CJ Griffiths, TJ Walls, D Veale, TN Stone, JW Osselton, P Hudgson and GJ Gibson Large-volume Paracentesis versus Dialytic Ultrafiltration in the Treatment of Cirrhotic Ascites KN Lai, PKT Li, E Law, R Swaminathan and MG Nicholls Single-dose Antibiotic Treatment for Symptomatic Urinary Tract Infections in Women: a Meta-analysis of Randomized Trials L Leiboviv and AJ Wysenbeek Autoimmunity, Inflammatory Bowel Disease and Hyposplenism FP Ryan, AM Ward and CD Holdsworth Large Granular T Lymphocytes, Neutropenia and Polyarthropathy: An Underdiagnosed Syndrome? N Snowden, M Bhavani, DR Swinson, JR Kendra, C Dennett, P Carrington, S Walsh and RSH Pumphrey Elderly Patients with Suppressed Serum TSH but Normal Free Thyroid Hormone Levels Usually Have Mild Thyroid Overactivity and are at Increased Risk of Developing Overt Hyperthyroidism DJ Stott, AR McLellan, J Finlayson, P Chu and WD Alexander Factors Determining Success and Energy Requirements for Cardioversion of Atrial Fibrillation: Revised Version GWN Daizell, J Anderson and AAJ Adgey No 286, February 1991 Immunosuppression and Mycobacterium sp Infection GC Cook Recent Developments in the Diagnosis and Management of Transient Ischaemic Attacks and Minor Strokes PAG Sandercock A Prospective Study to Evaluate the Dose of Vitamin D Required to Correct Low 25- Hydroxyvitamin D Levels, Calcium, and Alkaline Phosphatase in Patients at Risk of Developing Antiepileptic Drug-induced Osteomalacia N Collins, J Maher, M Cole, M Baker and N Callahan Detection of Hepatitis B Virus DNA Sequences in Liver in HBsAg Seronegative Patients with Liver Disease with and without Anti-HBc Antibodies EA Fagan, FD Davison, R Trowbridge, WF Carman, HM Smith, R Tedder and R Williams Low-dose Cyclopenthiazide in the Treatment of Hypertension: A One-year Community- based Study GD Johnston, R Wilson, BJ McDermott, GE McVee, D Duffin and J Logan Mycobacterial Infections After Renal Transplantation RM Higgins, AP Cahn, D Porter, AJ Richardson, RG Mitchell, JM Hopkin and PJ Morris Effect of Recombinant Alpha,-Interferon with or without Prednisone in Chinese HBsAg Carrier Children C-L Lai, H-J Lin, JY-N Lau, AS-F Lok, H-T Chung, LS-K Wong, MP Leung and C-Y Yeung Effects of Cranial Irradiation on Hypothalamic-Pituitary Function — a 5-Year Longitudinal Study in Patients with Nasopharyngeal Carcinoma KSL Lam, VKC Tse, C Wang, RTT Yeung and JHC Ho Hypomagnesaemia in Elderly Hospital Admissions: A Study of Clinical Significance BJ Martin, J Black and AS McLelland Hypothalamic Syndrome and Central Sleep Apnoea Associated with Toluene Exposure S Teelucksingh, CR Steers, CJ Thompson, JR Seckl, NJ Douglas and CRW Edwards No 287, March 1991 The Medical Management of Zollinger-Ellison Syndrome JM Rhodes The Polymerase Chain Reaction WF Carman Joint and Systemic Distribution of Dialysis Amyloid NA Athanasou, D Ayers, AJ Rainey, DO Oliver and RB Duthie Changing Patterns in Presentation and Management of the Zollinger-Ellison Syndrome in Northern Ireland, 1970-1988 JSA Collins, KD Buchanan, TL Kennedy, CF Johnston, JES Ardill, JM Sloan, EM Mcllrath and C Russell The Initial Electrocardiogram in Patients Seen by a Mobile Coronary Care Unit GWN Daizell, J Purvis and AAJ Adgey Non-Typhoid Salmonella in Renal Transplant Recipients: a Report of Twenty Cases and Review of the Literature JM Dhar, AA Al-Khader, M Al-Sulaiman and MK Al-Hasani Pseudohypoparathyroidism: Its Phenotypic Variability and Associated Disorders in a Large Family CM Faull, RR Welbury, B Paul and P Kendall-Taylor Endocrine and Reproductive Dysfunction Following Fractionated Total Body Irradiation in Adults MD Littley, SM Shalet, GR Morgenstern and DP Deakin Abdominal Pain in HIV Infection PJ Thuluvath,GM Connolly, A Forbes and BG Gazzard No 288, April 1991 Diabetic Proximal Neuropathy: Therapy and Prognosis M Donaghy The Pathophysiology, Clinical Features and Management of Rotavirus Diarrhoea IE Haffajee Rickettsial Infection of the Central Nervous System: the Role of Prompt Antimicrobial Therapy Y Shaked The Natural History of Diabetic Femoral Neuropathy SW Coppack and PJ Watkins Liver Damage in Long-term Anticonvulsant Therapy: A Serological and Histological Study GR Foster, RD Goldin, CJ Freeth, E Nieman and DBG Oliveira Total Parathyroidectomy Alone or with Autograft for Renal Hyperparathyroidism? RM Higgins, AJ Richardson, PJ Ratcliffe, CG Woods, DO Oliver and PJ Morris IgM-Associated Primary Diffuse Mesangial Proliferative Glomerulonephritis: Natural History and Prognostic Indicators DJ O’Donoghue, W Lawler, LP Hunt, EJ Acheson and NP Mallick Variable Hormonogenesis in Cushing’s Syndrome MS Shapiro and L Shenkman The Determinants of Early Nephropathy in Insulin-dependent Diabetes Mellitus: A Prospective Study Based on the Urinary Excretion of Albumin GF Watts, R Harris and KM Shaw No 289, May 1991 Aortic Dissection CM Oakley The Molecular Biology of von Willebrand’s Disease GR Standen and IR Peake Diagnostic Delay and Outcome in Surgery for Type A Aortic Dissection J Butler, OJM Ormerod, N Giannopoulos, R Pilliai and S Westaby Antibodies to Cardiolipin in Stroke: Association with Mortality and Functional Recovery in Patients without Systemic Lupus Erythematosus KK Chakravarty, MA Byron, M Webley, CJ Durkin, AH Al-Hillawi, R Bodley and J Wozniak Aluminium Mobilization Following Renal Transplantation and the Possible Effect on Susceptibility to Bacterial Sepsis A Davenport, AM Davison, EJ Will, KE Newton and C Toothill Intracranial and Intracerebral Perfusion Pressure Changes Before, During and Immediately After Orthotopic Liver Transplantation for Fulminant Hepatic Failure R Keays, D Potter, J O’Grady, T Peachey, G Alexander and R Williams A Pre-eclamptic-like Syndrome Association with Hypothyroidism During Pregnancy S Patel, S Robinson, RJ Bidgood and CJ Edmonds Proximal Cutaneous Necrosis Associated with Small Vessel Calcification in Renal Failure CN Ross, MJD Cassidy, M Thompson, R Russell-Jones and AJ Rees The Clinical Entity of Orofacial Crohn’s Disease AJK Williams, D Wray and A Ferguson No 290, June 1991 Autosomal Dominant Polycystic Kidney Disease ST Reeders Rheumatoid Arthritis: Workload and Outcome over 10 Years HA Capelli, EA Murphy and JA Hunter Polycystic Kidney Disease Re-evaluated: A Population-based Study F Davies, GA Coles, PS Harper, AJ Williams, C Evans and D Cochlin Thrombolytic Therapy Within One Hour of the Onset of Acute Myocardial Infarction AJ McNeill, DJ Flannery, CM Wilson, GWN Dalzell, NPS Campbell, MM Khan, GC Patterson, SW Webb and AAJ Adgey The Influence of Autonomic Neuropathy on Mortality in Insulin-dependent Diabetes IA O’Brien, JP McFadden and RJM Corrall Treatment of Type | Gaucher’s Disease Affecting Bone with Aminohydroxypropylidene Bisphosphonate (Pamidronate) L Ostlere, T Warner, PJ Meunier, P Hulme, R Hesp, RWE Watts and J Reeve Perspectives in Multiple Myeloma: Survival, Prognostic Factors and Disease Complications in a Single Centre Between 1975 and 1988 HC Rayner, AP Haynes, JR Thompson, N Russell and J Fletcher Upper Airway Obstruction and Pulmonary Function in Acromegaly: Relationship to Disease Activity B Trotman-Dickenson, AP Weetman and JMB Hughes The Association of Different Measures of Insulinaemia with Vascular Risk Factors in Healthy Normoglycaemic Normotensive Non-obese Men and Women PH Winocour, S Kalyuva, L Brown, M Farrer, JP Millar, HAW Neil and KGMM Alberti No 291, July 1991 Very early thrombolysis: the challenge and the reality DP de Bono HIV infection and tuberculosis JH Darbyshire Circulating Anti-neutrophil Cytoplasmic Autoantibodies in Subglottic Stenosis: a Useful Aid in Diagnosing Vasculitis in This Condition? ROB Gans, N de Vries, AJM Donker, R Goldschmeding and SJ Hoorntjes Intra-articular Chlamydial Antigen and Inflammatory Arthritis RA Hughes, E Hyder, JD Trehearne and ACS Keat Pulmonary Hypertension in Aortic Regurgitation: Early Surgical Outcome DP Naidoo, AS Mitha, S Vythilingum and S Chetty Gene Probe Analysis in an Informative Family with Multiple Endocrine Neoplasia Syndrome Type 2A (MEN 2A) Improvement in Carrier Risk Estimation PJ Morrison, DR Hadden, AE Hughes, L Kennedy, CJF Russell and NC Nevin Prevalence and Significance of Haematological Abnormalities in Patients with Systemic Lupus Erythematosus JC Nossent and AJG Swaak Tuberculosis in Patients infected with the Human Immunodeficiency Virus ELC Ong and BK Mandal Nebulized Pentamidine for the Prevention of Pneumocystis carinii Pneumonia in AIDS Patients: Experience of 173 Patients and a Review of the Literature DE Smith, DA Hills, C Harman, DA Hawkins and BG Gazzard No 292, August 1991 The Natural History of Low Grade Non-Hodgkin’s Lymphoma and the Impact of a No Initial Treatment Policy on Survival DH Wright The Pattern of Rheumatoid Arthritis in West Africa and Comparison with a Cohort of British Patients AO Adebajo and DM Reid Frequency of Asymptomatic Hepatitis Types B and C in an Inner City Community and Relation to Possible Risk Factors R King, PJ Johnson, YS White, HM Smith and R Williams The Natural History of Low Grade Non-Hodgkin’s Lymphoma and the Impact of a No Initial Treatment Policy on Survival MER O’Brien, P Easterbrook, JP owell, GRP Blackledge, L Jones, ICM MacLennan and RCF Leonard Peripheral Nerve Dysfunction in Scleroderma W Schady, A Sheard, A Hassell, L Holt, MIV Jayson and P Klimiuk Children with Atopic Eczema. I: Clinical Response to Food Elimination and Subsequent Double-blind Food Challenge KS Sloper, J Wadsworth and J Brostoff Children with Atopic Eczema II: Immunological Findings Associated with Dietary Manipu- lations KS Sloper, J Wadsworth and J Brostoff No 293, September 1991 Glucose Counter-regulation in Health and Disease: Current Concepts in Hypoglycaemia Recognition and Response S Amiel Long-term Survival After Resuscitation From Ventricular Fibrillation Occurring Before Hospital Admission W Dickey, G MacKenzie and AAJ Adgey Acute Cerebrovascular Episodes in Systemic Lupus Erythematosus S Eustace, M Hutchinson and B Bresnihan Bites by the King Cobra (Ophiophagus hannah) in Myanmar: Successful Treatment of Severe Neurotoxic Envenoming Tin-Myint, Rai-Mra, Maung-Chit, Tun-Pe and DA Warrell Prevalence of Persistent Cough During Long-term Enalapril Treatment: Controlled Study Versus Nifedipine WW Yeo, G Foster and LE Ramsay Massive Cystic Hepatomegaly in a Female Patient with Polycystic Kidney Disease Treated by Combined Hepatic and Renal Transplantation JE Taylor, RY Calne and WK Stewart Eighty-fifth Annual General Meeting of the Association of Physicians of Great Britain and Northern Ireland No 294, October 1991 \ The Management of Asthma in the Community: Problems of Compliance with Treatment GM Cochrane and GR Horn The Management of Chronic Renal Failure: Ten Unanswered Questions AM EI Nahas and JP Wight Comparative Trial of Norfloxacin and Macrocrystalline Nitrofurantoin (Macrodantin) in the Prophylaxis of Recurrent Urinary Tract Infection in Women W Brumfitt, JMT Hamilton-Miller, GW Smith and W Al-Wali Out-of-hospital Ventricular Fibrillation in Patients Under the Age of 40 Years and the Long- term Prognosis W Dickey and AAJ Adgey Patterns of Insulin Dependence in an African Diabetic Clinic GV Gill and KR Huddle Failure of Dietary Protein and Phosphate Restriction to Retard the Rate of Progression of Chronic Renal Failure: A Prospective, Randomized, Controlled Trial PS Williams, ME Stevens, G Fass, L Irons and JM Bone Neurological Manifestations of Systemic Lupus Erythematosus: A Prospective Study KL Wong, EKW Woo, YL Yu and RWS Wong Actinobacillus actinomycetemcomitans Endocarditis: A Report of Four Cases and Review of the Literature Y-C Chen, S-C Chang, K-T Luh and W-C Hsieh No 295, November 1991 Renal Biopsy and the Prognosis of Lupus Nephritis AEG Raine Barrett’s Oesophagus—A Review CSJ Probert, V Jayanthi and JF Mayberry Endocrine Function, Psychiatric and Clinical Consequences in Patients with Macroprolacti- nomas After Long-term Treatment with the New Non-ergot Dopamine Agonist CV205-502 PS Barnett, E Palazidou, JP Miell, PB Coskeran, J Butler, JM Dawson, J MacCabe and AM McGregor Predictors of One-year Outcome in Lupus Nephritis: the Importance of Renal Biopsy JM Esdaile, W Federgren, H Quintal, S Suissa, JP Hayslett and M Kashgarian The Antihypertensive and Metabolic Effects of Low and Conventional Dose Cyclopenthia- zide in Type II Diabetics with Hypertension AP Passmore, EM Whitehead, V Crawford, GE McVeigh and GD Johnston Ganciclovir Treatment for Cytomegalovirus Infection in Immunocompromised Patients With Renal Disease CN Ross, HLC Beynon, JS Savill, RP Watkins, J Cohen, CD Pusey and AJ Rees A Long-term Clinical Review of Patients With Oesophageal Pain GL Swift, H Alban-Davies, H McKirdy, R Lowndes, D Lewis and J Rhodes Familial Nephropathic, Non-neuropathic Amyloidosis: Clinical Features, Immunohisto- chemistry and Chemistry AM Zalin, S Jones, NJS Fitch and DB Ramsden No 296, December 1991 Resuscitation—Time for a Re-think? D De Bono Mechanisms of Sleep-disordered Breathing in Chronic Neuromuscular Disease: Implications for Management PEM Smith, RHT Edwards and PM Calverly Pulse Cyclophosphamide for Severe Neuropsychiatric Lupus DT Boumpas, H Yamada, NJ Patronas, D Scott, JH Klippel and JE Blalow The Effect of External Pituitary Irradiation on Elevated Serum Prolactin Levels in Patients with Pituitary Macroadenomas MD Littley, SM Shalet, H Reid, CG Beardwell and ML Sutton Sputum Examination in the Screening and Diagnosis of Pulmonary Tuberculosis in the Elderly CDW Morris Age and Other Determinants of Survival after In-hospital Cardiopulmonary Resuscitation S O’Keeffe, C Redahan, P Keane and K Daly Measurement of Lung Tissue Mass in Interstitial Lung Disease DJ Seddon and PD Snashall The Coventry Diabetes Study: Prevalence of Diabetes and Impaired Glucose Tolerance in Europids and Asians D Simmons, DRR Williams and MJ Powell Study of Lupus Nephritis in Males S Tateno, Y Hiki, K Hamaguchi, H Tsuchida, H Shigematsu and Y Kobayashi Medicine in Sheffield HT Swan Subject Index Abdominal! pain Arthritis HIV infection, 78:275 inflammatory, anti-Chlamydia antibodies, Acromegaly 80:575 lung function/upper airways obstruction, Ascites 77:527 cirrhotic, treatment, dialytic ultrafiltration Actinobacillus actinomycetemcomitans paracentesis, 78:33 endocarditis, 81:871 Asthma AIDS management, compliance, 81:797 Pneumocystis carinii pneumonia, prophy- Atopic eczema laxis, nebulized pentamidine, 80:619 food elimination studies/immunology, Alkaline phosphatase 80:677; 695 levels, antiepileptic drugs effects on, 78:113 Atrial fibrillation Aluminium factors affecting success, 78:85 mobilization, renal transplant patients, Autoimmunity effects on bacterial sepsis, 79:407 association with inflammatory bowel disease Aminohydroypropylidene bisphosphonate +hyposplenism, 78:59 treatment of Gaucher’s disease, bone, Autonomic neuropathy 79:503 effects on mortality, diabetes, 79:495 Amyloid Barrett's oesophagus deposition, dialysis patients, 78:205 review, 81:883 Amyloidosis Calcification familial, nephropathic, non-neuropathic, small vessels, association with proximal cuta- 81:945 neous necrosis, renal failure, 79:443 Antibiotics Calcium single-dose, urinary tract infections treat- levels, antiepileptic drugs effects on, 78:113 ment, women, 78:43 Cancer ANCA nasopharynx, cranial irradiation effects on subglottic stenosis, 80:565 hypothalamus/pituitary, 78:165 Antibodies stomach/oesophagus, during cimetidine anti-cardiolipin, stroke patients, 79:397 treatment, 78:13 anti-Chylamydia, intra-articular, inflamma- Cardiolipin tory arthritis, 80:575 antibodies, stroke patients, 79:397 anti-neutrophil cytoplasmic, subglottic ste- Cardiopulmonary resuscitation nosis, 80:565 see resuscitation Anticonvulsants Central nervous system effects on liver, 79:315 Rickettsia infection, treatment, 79:301 Antiepileptic drugs Central sleep apnoea associated osteomalacia, prevention, 78:113 association with toluene exposure, 78:185 Aortic dissection Cerebrovascular episodes type A, diagnosis/surgery, 79:379; 391 acute, systemic lupus erythematosus, 80:739 Aortic regurgitation Children pulmonary hypertension, surgical outcome, HBsAg carriers, treatment, «2-inter- 80:589 feron + prednisone, 78:155 Chlamydia ECG antibodies, intra-articular, inflammatory mobile coronary care units, 78:227 arthritis, 80:575 Eczema Cimetidine food elimination studies/immunology, treatment, stomach/oesophagus carcinoma 80:677; 695 incidence, 78:13 Enalapril Cirrhosis association with persistent cough, 80:763 ascites, treatment, dialytic ultrafiltration Endocarditis paracentesis, 78:33 Actinobacillus actinomycetemcomitans, 81: Coronary care units 871 mobile, presenting ECG, 78:227 Endocrine system Cough dysfunction following total body irradiation, association with enalapril treatment, 80:763 78:265 Cranial irradiation function, CV205-502 treatment effects on, nasopharyngeal carcinoma patients, effects macroprolactinomas, 81:891 on hypothalamus/pituitary, 78:165 hormonogenesis, Cushing’s syndrome, Crohn’s disease 78:357 orofacial, 79:451 Envenoming Cushing’s syndrome neurotoxicity, Ophiophagus hannah bites, hormonogenesis, 79:357 treatment, 80:751 Cyclopenthiazide Femoral neuropathy low-dose, treatment of hypertension, 78:135 diabetes, 79:307 low-dose/conventional, treatment of hyper- Ganciclovir tension, 81:919 treatment of cytomegalovirus infection, Cyclophosphamide immunosuppressed patients, 81:929 pulse, treatment of neuropsychiatric lupus, Gaucher’s disease 81:975 bone, treatment, pamidronate, 79:503 Cytomegalovirus Genetics infection, immunocompromised patients, gene probe analysis, MEN 2A, carrier risk treatment, ganciclovir, 81:929 estimation, 80:597 Diabetes Geriatrics autonomic neuropathy, 79:495 hyperthyroidism risk, 78:77 early nephropathy, 79:365 hypomagnaesemia, clinical significance, Europids/Asians, 81:1021 78:177 femoral neuropathy, 79:307 tuberculosis diagnosis/screening, sputum hypertension, treatment, cyclopenthiazide, examination, 81:999 81:919 Glomerulonephritis insulin dependence, Africa, 81:821 primary diffuse mesangial proliferative, IgM proximal neuropathy, 79:287 associated, 79:333 Dialysis (see also haemodialysis, peritoneal di- Glucose alysis) counter-regulation, review, 80:707 amyloid deposition, 78:205 impaired tolerance, Europids/Asians, Dialytic ultrafiltration 81:1021 cirrhotic ascites treatment, 78:33 Haematology Diarrhoea systemic lupus erythematosus, 80:605 rotavirus, review, 79:289 Hepatitis B DNA sequences asymptomatic, epidemiology, inner city area, hepatitis B virus, detection, liver, HBsAg- 80:641 negative hepatitis, 78:123 Hepatitis C Dopamine asymptomatic, epidemiology, inner city area, agonist, CV 205-502, treatment of macropro- 80:641 lactinoma, 81:891 Hepatitis B virus Drug surveillance DNA sequence detection, liver, HBsAg-nega- post-marketing, 78:1 tive hepatitis, 78:123