Pyrrolizidine Alkaloid Containing Plants

82 Pages·2008·9 MB·English

by  Bryan Stegelmeier

Pyrrolizidine Alkaloid Containing
Plants
Bryan Stegelmeier
ADVS 586
February 12, 2008
PPRL 2008
PPRL 2008
Pyrrolizidine alkaloid containing plants are the
most widespread and expensive poisonous
plant problem that affects plants, insects,
animals and humans.
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Outline
Toxin
Plants
Poisoning
Susceptibility
Metabolism
Clinical signs
Lesions
Diagnosis
Current Research
Future Objectives
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Pyrrolizidine alkaloids: Structure
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PA Global Problem
>6000 plants contain PA’s
Most common poisonous plant
affecting livestock, wildlife, and
humans
Invasive noxious weeds
Contaminated feed, food and
herbal preparations
Wide range of susceptibility
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Plants Containing Pyrrolizidine Alkaloids
Compositae
Senecio (1200 species)
(cid:122)
S. jacobaea (tansy ragwort)
(cid:122)
S. vulgaris (common groundsel)
(cid:122)
S. longilobus (threadleaf groundsel)
(cid:122)
S. riddellii (Riddell groundsel)
(cid:122)
Fabaceae (Liguminosae)
Crotalaria (600 species)
(cid:122)
C. sagittalis (rattlebox)
(cid:122)
C. spectabilis (showy crotalaria)
(cid:122)
C. retusa (wedge-leaf rattlebox)
(cid:122)
C. pallida (smooth crotalaria)
(cid:122)
C. juncea (sun hemp)
(cid:122)
Boraginacea
Amsinckia intermedia (tarweed)
(cid:122)
Borago officinalis (borage)
(cid:122)
Cynoglossum officinale (hound’s tongue)
(cid:122)
Echium plantagineum (echium)
(cid:122)
Echium vulgare (vipers bugloss)
(cid:122)
Heliotropiu europaeum (heliotrope)
(cid:122)
Symphytum officinale (comfrey)
(cid:122)
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Compositae
Senecio (1200 species)
S. jacobaea (tansy ragwort)
(cid:122)
S. vulgaris (common groundsel)
(cid:122)
S. longilobus (threadleaf groundsel)
(cid:122)
S. riddellii (Riddell groundsel)
(cid:122)
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Senecio jacobea
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Senecio riddellii
.
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