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10 12 14 Research Register Today BCVS 2015 Networks Update for International Stroke Scientific Sessions Conference 2016 SERVING SCIENTIFIC COUNCILS FALL 2015 | VOL. 13 | NO. 3 CONNECTIONS CONNECTIONS Scientific Sessions 2015 Is Bigger and Better Customize your Scientific Sessions experience with new areas of interest/tracks and hands-on learning opportunities Scientific Sessions keeps you on the cut- ting edge of cardiovascular science and clinical practice. That’s right! Five days of comprehensive, unparalleled education, late- breaking clinical trials and basic science, oral abstract sessions, poster presentations, named lectures and so much more. AHA brings you a re- Join us in Orlando, Florida, for new areas of interest and hands-on learning at Scientific Sessions 2015. freshed and reshaped Scientific Sessions in 2015. Areas of Interest The American Heart Association AHA has lined up can’t-miss programming and segmented the meeting into 30 highly targeted Names Six Distinguished Scientists areas of interest to allow you to focus your time and more easily navigate the meeting. The American Heart Association disease and stroke. The awardees will join Programming for Scientific Sessions 2015 is has designated six Distinguished the ranks of 85 other eminent researchers divided into five main categories: Basic, Clini- Scientists for 2015. These renowned and scientists and will be recognized at the cal, Population, Special Focus and Frontiers scientists will be honored by the Opening Session of Scientific Sessions 2015 in Science. Each category features a number association for their research that has in Orlando. see SESSIONS, page 2 advanced the understanding of cardiovascular see DISTINGUISHED SCIENTISTS, page 6 my.americanheart.org COUNCIL NEWS my.americanheart.org Arteriosclerosis, Thrombosis Cardiovascular Disease in the Young 22 Epidemiology and Prevention 32 Lifestyle and Cardiometabolic Health 40 COanUdN VaCsIcLul aNr BEioWloSgy 16 AanrtBde arVisoaiscscc Cluealraorrds Biisoi,ov Tlaohsgrcoyu mlabr oSscisie nces 618 CCaaCCrrddaaiirrooddvviiooaavvssaaccssuucclluaaulrral aaDrr nR isadaen daSdisto Sreloo tikrgnoey kt Nhaene uNd rYsu oIinrnustgeinn rggv e ntion11 242246 EFpuFBinduiceontmlicooitgnoioylaon lg aGyl eaGnneodnm Poirmcesvic easnn taidon nTd r aTnrasnlastliaotnioanl al 2234 NPeuPQrtireupitrahiiopleinthry,ae Plor ahVf lya CVssaiaccrsuaecll a uaArnl caDdtri i vsDOietiyusa teascaneosd me M ese tRabeoselisamrc h33 024424 BaCPseaicrri doCipoaeprdruailotmivvoaens acanurydl,a RrC Serisctiuicesanclc iCteaastri oen, (3CPR) 820 CaCrdairodviaosvcauslcaur lRara dSiuorloggeyry a anndd I nAtenrevsetnhteiosnia 1628 BioHlyopgeyr tension 2436 QuSatlriotyk eo f Care and Outcomes Research 3446 CPearridoipoeprualtmivoen aanryd, RCeristiucsacl iCtaatrioen, (3CPR) 10 CCaliCnrdliicnioaicvl aaCls aCcrudaliraodrli ooSgluoyrg gye ry and Anesthesia 128030 HKiidgKnhide Bnyel oiyno idCn aPCrrdaeirsodsviouavrseac suRcleausrl aeDra irsDceihsa esaes e 226838 Stroke 36 SESSIONS • Heart Failure and Cardiomyopathies continued from page 1 • Hypertension of areas of interest to allow you to focus your • Imaging education in your specialty or expand your • Vascular Disease knowledge in other areas. But most important, • Stroke you will be able to locate what you need faster • Nursing Clinical Symposium and more easily than ever before. The Population Science programming pro- Basic Science programming seeks to pro- vides awareness of the most effective popula- vide state-of-the-art insights into the underly- tion-based approaches to preventing cardiovas- ing mechanisms of cardiovascular development cular diseases and improving cardiovascular and disease. These insights ultimately could health across populations. Population Science lead to the development of effective new inter- features these areas of interest: ventions to better diagnose, treat and prevent • Prevention and Rehabilitation cardiovascular disease. Specific areas of inter- • Obesity and Cardiometabolic Health est with the Basic Science category are: • Lifestyle Risk Factors and Behavior Change • Arteriosclerosis, Vascular Biology and Devel- • Quality of Care and Outcomes opment • Epidemiology Scientific Sessions 2015 is five days of comprehensive, unparalleled education, late- • Cardiac Development, Structure and Function • Population Health Cohorts — Big Data breaking clinical trials and basic science, • Genetics and Genomics • Workplace Health oral abstract sessions, poster presentations, • Metabolism and Physiology • Health Tech named lectures and so much more. • Cellular Biology and Function • Signaling Mechanisms and Drug Discovery The Special Focus programming is com- The Frontiers in Science meetings deliver • Thrombosis, Immunity and Inflammation prised of various topics within cardiovascular one-day, science-focused gatherings that provide disease that are of continuing concern to clini- an intimate setting for the free exchange of new Clinical Science programming aims to pro- cians, including the use of innovative tools and ideas. Scientists come together for intense open vide access to the latest clinical and scientific technologies. Four areas of interest comprise science discussion to encourage the cross-polli- applications in the diagnosis, medical manage- the Special Focus programming. nation of new concepts and ideas. Speakers pres- ment, prevention and treatment of cardiovascu- • Nursing Science ent in a rapid-fire format, encouraging discussion lar disease. The areas of interest in the Clinical • Clinical Trialists throughout the day. Because Frontiers in Science Science category are: • Lifelong Congenital Heart Disease and Heart meetings focus on pre-discovery/pre-publication • Chronic and Acute Ischemic Heart Disease Health in the Young topics, there is no recording of lectures or discus- • Arrhythmias and Electrophysiology • Resuscitation Science Symposium sion; ideas are not meant to be disseminated to • Intervention and Surgery the public. Frontiers in Science features: • Arrhythmia Research Summit • Vascular Disease 2015 Guidelines Instructor Conference Don’t miss your opportunity to receive your required Guidelines Instructor update from the 5 AHA at the 2015 Guidelines Instructor Con- 1 0 ference on Friday, Nov. 6, prior to Scientific 2 Sessions. L L Using a conference format, attendees will A F receive a comprehensive science update, and then S add sessions for each discipline. AHA science N experts, volunteers and staff will outline what O TI the new guidelines mean for teaching lifesaving C E CPR and ECC courses. BLS, ACLS and PALS N sessions will be offered multiple times throughout N O the day of the conference. C The Guidelines Instructor Conference includes a fourth educational track for instructor Scientific Sessions 2015 will be held at the Orange County Convention Center in Orlando, Florida. development and enrichment. 2 my.americanheart.org Second Annual Health Tech Competition Health Tech sessions explore the role of EXPECT technology in the treatment and preven- tion of cardiovascular disease, examine BIG Science ways to drive innovation and collabora- BIG Clinical Content tion in the marketplace and, ultimately, BIG Technology drive toward a health-technology road- BIG Networking map with the goal of improved outcomes. See why Scientific Sessions is the global conference of choice for THINGS Genomics Boot Camp cardiovascular professionals. Familiarize yourself with the basic prin- ciples of genetics and genomics and how they are being applied to the practice of a Global 23 medicine during this Sunday morning Perspective 17,000 boot camp. FROM SPECIAL & NAMED Attendees of Scientific Sessions 2015 countries CARDIOVASCULAR lectures who have an interest in learning about 45% international PROFESSIONALS 55% domestic clinical genomics, especially non-scien- tists and clinical practitioners (including physicians, nurses, pharmacists, etc.) are who attends: welcome to attend this flipped classroom RESEARCHERS • CLINICIANS • NURSES +1.5 million EMTs • Technicians • Pharma • Students • Early Career boot camp. virtual attendees All Genomics Boot Camp participants must complete the Basic Concepts in Ge- netics and Genomics CME/CE activity on 5,000+ 200+ exhibitors learn.heart.org prior to the event. A certifi- the technology + resources cate of completion must be presented for presentations BEST entry. Boot Camp is included in Sessions INCLUDING registration, but attendees will need to go science 1,500 INVITED Hands-on to the Registration Resource Center to FACULTY activities secure their seat for this program. 4,000 ABSTRACTS in new SIMULATION More BIG Things ZONE Scientific Sessions 2015 offers a unique LATEST-BREAKING Clinical Trials opportunity to gather with colleagues from around the world in an exciting ed- ucational and professional environment. ARRHYTHMIA 30 programming RESEARCH SUMMIT The scope and quality of the scientific tracks Become a Cardiovascular Nursing exchange make Scientific Sessions the Clinical Symposium PROFESSIONAL INCLUDES 3 NEW premier cardiovascular research and MEMBER C educational meeting in the world. ReSS TRACKS: and save up to $400 ON More than 17,000 cardiovascular Clinical Trialists on registration N E healthcare professionals attended Scien- are now part of C tific Sessions last year, including 6,000 Health Tech T SCIENTIFIC IO CONTINUING international attendees who come from N SESSIONS Workplace Health EDUCATION more than 100 countries. credits available S F A BIG Breakthroughs L L Late-Breaking Clinical Trials bring Exhibits: November 8–10 LEARN MORE 2 you face-to-face with leading experts in 0 1 the cardiovascular field as they unveil Sessions: November 7–11 scientificsessions.org/ 5 registrationandhousing the latest breakthroughs in clinical science. These innovative presentations my.americanheart.org 3 likely will have a significant impact on your increasing number of patients, new diagnostic Developed by AstraZeneca, Conference clinic practice, making them one of the must- dilemmas challenge the clinician. The Notes is available on iPad and through a web see forums at Scientific Sessions. The Clinical Mechanical Circulatory Support Simulation browser for laptop viewing. Science Special Report sessions highlight provides a hands-on opportunity to model trial updates, registries and important clinical critical scenarios and observe hemodynamic BIG Events science in a variety of specialties. To extend consequences. A total artificial heart mock Never stop learning. In addition to the hundreds your learning, you can connect with the circulatory loop paired with both axial and of presentations and educational opportunities researchers involved in select trials through centrifugal continuous flow devices will test at Scientific Sessions, you also have access to the Meet the Trialists program. Located in scenarios such as inadequate preload/afterload Unofficial Satellite Events — independently the Science & Technology Hall, Meet the conditions, right heart failure and device organized scientific and educational activities Trialists affords you the opportunity to get your obstruction. offered and/or accredited by various sponsoring questions answered in a casual setting. organizations. These events will be held during BIG Innovation Scientific Sessions 2015 before and after of- BIG Hands-On Experiences Schedule time to explore the Science & Tech- ficial programming, giving you an opportunity Presented in AHA’s newly formed Simulation nology Hall, where you’ll discover the latest for additional learning and networking. Visit Center, located on the Science and Technology in technology, services and products. You will scientificsessions.org for a list of events. Hall Floor, Body Interact is a cloud-based im- find areas dedicated to the tools and resources mersive training platform that virtualizes acute for your business and practice. Check out the BIG Information and chronic medical conditions. It provides Cardiovascular Expert Theaters to find specific HeartQuarters, located in Booth 859 in the realistic user experiences with a life-like virtual products and therapeutic treatments, and visit Science & Technology Hall, is your one-stop patient, complete with dynamic monitoring, the Emerging Science & Technology Showcase location for all things American Heart As- dialoguing, test orders, scans, drugs, interven- to see the latest technologies in prevention, sociation. Here you can find information about tion options and performance debriefing. diagnosis and treatment of cardiovascular professional membership and councils, browse Body Interact offers dozens of medical case disease. various scientific publications explore online study scenarios, including cardiology, respira- professional education activities and attend tory, infectious disease and diabetes. Scientific BIG Technology events in the theater. Sessions 2015 attendees might be particularly If you aren’t following Scientific Sessions 2015 Check out our new layout featuring the interested in the following categories of avail- on your smartphone or mobile device, you’re Collaboration Station, Shop Heart, Science and able cases: stroke, cholesterol, atrial fibrillation missing out. Patient and Consumer program. Our theater and heart failure. Get instant access to educational sessions, will hold hourly presentations. Also, check out The Simulation Zone is also where eposters, abstracts, faculty, event information, our interactive map or find colleagues from you’ll find Mechanical Circulatory Support hotels, schedule planning and maps by around the world. Simulation. The field of mechanical circulatory downloading the 2015 Mobile Meeting Guide. support provides longer and improved This app will help you navigate the meeting BIG Fitness quality of life for patients and end stage heart as well as ask questions and engage with big- Just because you’re traveling doesn’t mean you failure. As innovation in this field impacts an name speakers in our most popular sessions have to kick your daily exercise routine to the live by using the Digital Moderator curb. AHA has planned several activities for component. Listen to live stream audio you. Wear Red on Monday, Nov. 9, to encourage from all of the educational sessions. awareness of women’s heart disease. Then Wear Navigate the meeting through the Your Sneakers Day will be Tuesday, Nov. 10, interactive map, get information on when we invite you to give your feet a break all of the Science & Technology Hall by trading your business shoes for comfortable exhibitors and expand your professional walking shoes. To ignite your competitive network. Additionally, with easy access side, we’ll host the Annual Sessions Walking to your Scientific Sessions photos, you Challenge, which will track your daily steps. can quickly share pictures on social The program will feed all numbers into a networks. Follow us on social media leaderboard so users can monitor their daily using #AHA15. progress and see how they compare to the Available in more sessions this year, leading walkers at Sessions. Conference Notes is an app that allows you to follow along with presentations BIG Opportunities in real time, bookmark important slides Early career members are invited to network To extend your learning, you can connect with the to revisit and add notes and sketches with senior investigators at the Early Career researchers involved in select trials through the Meet the Trialists program. directly on your screen. Day on Saturday, Nov. 7. 4 my.americanheart.org Consider participating in our Peripheral Vascular Disease Fellows in Training Workshop, which is designed to enable vascular and cardiovascular post-graduate trainees and junior faculty to more effectively identify and treat peripheral vascular disorders. The workshop brings together trainees from diverse disciplines, including cardiovascular and vascular medicine, vascular surgery, interventional cardiology and interventional radiology to facilitate discussion of the common evidence-based practices. At the Early Career Engagement Lounge, you can meet the experts, learn how AHA membership can help you achieve your goals, network with peers and see what other attendees are saying on our social media sites. BIG Discoveries Don’t miss the cutting-edge original research presented through Posters and ePosters that are displayed in the Poster Hall. You can view these at personal workstations or on your smartphone. You also are encouraged to go online and communicate with presenters via email. Posters presenters will be able to network with Poster Professors — the top researchers in Get instant access to educational sessions, faculty, abstracts, event information, hotels, schedule a presenter’s field of interest — who will make planning and maps by downloading the 2015 Mobile Meeting Guide. rounds to welcome and network with poster presenters for increased interaction and robust discussion. tendees, with a global presence from more than tion. There will be a dedicated discussant for The Best of AHA Specialty Conferences 100 countries, making it the perfect place to each group of five abstracts in the abstract oral Poster Session features the top 10 percent expand your network and share your knowledge session. of abstracts presented at the 2015 specialty on cardiovascular diseases and stroke with Early Career Investigator Award Ses- conferences. Meet these poster presenters from like-minded professionals. Several networking sions will recognize promising and outstanding 9:30 to 11 a.m., Monday, Nov. 9. events are available during the week, including investigators in the early stages of their careers, An addition to our Poster program is the Meet the Trialists, Case Theaters: Learning stimulate continued interest in basic or clinical Basic Science Reception, which recognizes the at the Movies, EP Central, Simulation Zone, research and help early career investigators best of basic science abstracts, as well as late- WiFi/Charging Lounges, Early Career Lounge, participate in AHA meetings. breaking basic science abstracts. It will be held council dinners, as well as the Members Circle Featured Research Sessions will offer from 5 to 7 p.m., Monday, Nov. 9. and the AHA Fellows Lounge. state-of-the-science lectures on compelling C O Check out the Case Theaters: Learning areas of research. Speakers in this category have N at the Movies, presentations that showcase BIG Programming not only made outstanding contributions to the N E technical aspects and management of proce- Got questions? Get answers during these field, but are also talented teachers and com- C dures performed in patients, accompanied by sessions, which allow you to interact with the municators. T IO a panel of experts for intense discussion. The presenter and generate meaningful discussion. Named Lectures/Council-Sponsored N Case Theaters are 45-minute live presentations Abstract Oral Sessions will have 15 Lectures are presented throughout the meeting S of case presentations by international experts minutes allotted for each abstract presenter (10 in honor of scientists and AHA volunteers who F A in challenging and controversial situations in minutes presentation followed by five minutes have made outstanding contributions to the field L L structural heart disorders, cardiac surgery, vas- of questions and answers). The moderators in and the American Heart Association. 2 cular intervention and advanced heart failure. the session also will serve as discussants. Each There is so much more to Scientific 0 1 discussant will be given 10 minutes to provide Sessions. For specific Council activities 5 BIG Networking a critical analysis of the studies and provide and programming, check your Council report Scientific Sessions attracts nearly 17,000 at- constructive criticism and informed interpreta- in this issue or visit scientificsessions.org. my.americanheart.org 5 DISTINGUISHED SCIENTISTS Dr. Goldhaber is president and founding direc- Investigation. He is the recipient of the William continued from page 1 tor of the nonprofit organization, North American Harvey Award of the American Society of Thrombosis Forum (NATFonline.org). He serves Hypertension, the Okamoto Award from Japan’s Samuel Z. Goldhaber, MD, as a section editor of Clinician Update and the Vascular Disease Research Foundation, the FAHA Cardiology Patient Page for Circulation. He runs Clinical Research Prize as well as the James B. Professor of Medicine a busy outpatient practice of general cardiology, Herrick Award, both from the American Heart Brigham and Women’s venous thromboembolism and atrial fibrillation Association. Dr. Pfeffer is an honorary fellow of Hospital patients, and oversees the inpatient Cardiology the Royal College of Physicians and Surgeons Boston Consult Service. of Glasgow and is the recipient of an Honorary Samuel Z. Goldhaber, Doctoral Degree from Sahlgrenska Academy, MD, professor of Medicine at Harvard Medical Marc Alan Pfeffer, MD, University of Gothenburg, Sweden. School, is section head of Vascular Medicine PhD, FAHA in the Cardiovascular Medicine Division at Dzau Professor of Howard A. Rockman, MD, Brigham and Women’s Hospital. He is director Medicine, Harvard FAHA of the BWH Thrombosis Research Group and Medical School Edward S. Orgain Professor serves as principal investigator of a broad range Senior Physician, of Cardiology of randomized clinical trials and observational Cardiovascular Division Professor of Medicine, studies related to the prevention, treatment and Brigham and Women’s Hospital Cell Biology and Molecular epidemiology of venous thromboembolism, Boston Genetics stroke prevention in atrial fibrillation and pre- Marc Pfeffer is the Dzau Professor of Duke University vention of recurrent myocardial infarction. Medicine at Harvard Medical School and senior Durham, North Carolina Dr. Goldhaber showed through a series of physician in the Cardiovascular Division at the Howard A. Rockman is an internationally clinical trials that right ventricular dilatation Brigham and Women’s Hospital in Boston. A recognized basic scientist in cardiovascular disease and hypokinesis predict an adverse prognosis in noted researcher, Dr. Pfeffer, along with his late who has made seminal discoveries in understand- acute pulmonary embolism. Furthermore, these wife, Dr. Janice Pfeffer, and Eugene Braunwald, ing the molecular mechanisms of cardiac hypertro- trials showed that systemic and catheter-based MD, is credited with introducing the concept phy and heart failure, with emphasis on the role of ultrasound-facilitated thrombolytic therapy that angiotensin-converting enzyme inhibitors G protein-coupled receptors in the development more rapidly than heparin restored normal could attenuate adverse ventricular remodelling and therapy of heart disease. He pioneered the use right ventricular function. He also conducted following myocardial infarction and that this use of the mouse as a model system by developing a randomized trial demonstrating that elec- would result in a prolongation of survival and miniaturized technologies to study murine cardiac tronic medical alerts for high risk inpatients not other clinical benefits. Since this initial discovery, pathophysiology. This work laid the foundation receiving venous thromboembolism prophylaxis he has had a principal role in several practice- for him, and the scientific community, to use reduce the symptomatic DVT and pulmonary changing clinical trials such as SAVE, CARE, genetically engineered mice to study molecular embolism rates by more than 40 percent. VALIANT, CHARM, PEACE, ARISE, TREAT, mechanisms of disease. Dr. Goldhaber serves as chair of the steering ALTITUDE, RED-HF, TOPCAT and ELIXA. In a landmark study, he disproved a long- committee of the National Heart, Lung, and Dr. Pfeffer is considered as a team builder standing theory that normalization of wall stress Blood Institute-sponsored ATTRACT Trial and takes pride in academic advancement of was critical in preventing heart failure. His work of DVT, which is testing pharmacomechani- trainees and junior faculty collaborating on the resulted in a paradigm shift in understanding how cal low-dose thrombolysis against standard trials. He is known for his fairness in data sharing the heart responds to pathological stress. In elegant anticoagulation to prevent postthrombotic and assisting others in developing meaningful studies, he discovered that phosphoinositide 5 syndrome. He serves on the steering commit- scholarly works from study databases. He sets 3-kinase has protein kinase activity and identified 1 0 tees of the GARFIELD Atrial Fibrillation and high standards for relationships with the sponsors for the first time an endogenous substrate for the 2 GARFIELD-Venous Thromboembolism cohort whether industry or NHLBI. enzyme and role in receptor endocytosis. Recently, L L studies and is national coordinator of U.S. Dr. Pfeffer is senior associate editor of he discovered how β-adrenergic and angiotensin A F participating sites. For his work on prevention Circulation and is a member of the editorial receptors in the heart can be selectively activated S of venous thromboembolism, Dr. Goldhaber has board of several other prominent journals. He to induce cardioprotective signaling, which has led N received the Certificate of Appreciation from the serves on the Data Safety Monitoring Boards to the development of a new class of drugs known O TI Surgeon General of the United States. of major international trials. An internationally as biased ligands. He has authored more than 200 C E Dr. Goldhaber directs a series of Harvard recognized expert in the field of cardiology, he articles, has received many mentoring and teaching N Medical School CME courses, including a five- was recognized by Science Watch as having the awards and has been elected to the Association of N O day update in clinical cardiology and a two-day most “Hot Papers” (highly cited) in all of clini- American Physicians and the American Society for C course on thrombosis and thromboembolism. cal medicine. Dr. Pfeffer was listed as one of Clinical Investigation. He is the current editor-in- He also tapes the “Clot Blog” for theheart.org the highly influential biomedical researchers of chief of the Journal of Clinical Investigation. on Medscape. 1996-2011 in the European Journal of Clinical 6 my.americanheart.org Jeffrey L. Saver, MD, FAHA bright Professor of Gerontology and director Russell P. Tracy, PhD, FAHA, ABCC, is Professor of Neurology of the Biobehavioral Research Center at the professor of Pathology and Laboratory Medicine Geffen School of University of Pennsylvania, School of Nursing. and Biochemistry in the College of Medicine at Medicine at UCLA She is co-editor of the Journal of Cardiovascular the University of Vermont, and director of the Director Nursing, which is the official journal of the Pre- Laboratory for Clinical Biochemistry Research. UCLA Comprehensive ventive Cardiovascular Nurses Association and He has served as senior associate dean of Research Stroke Center endorsed by the AHA Council on Cardiovascular and Academic Affairs in the College of Medicine, Los Angeles and Stroke Nursing. and currently serves on the Board of Trustees of Jeffrey L. Saver is director of the UCLA Com- Dr. Riegel is an established nurse scientist the UVM Medical Center. After graduate training prehensive Stroke Center, and professor and senior studying adults with cardiovascular disease. Her at Syracuse University in biochemistry, he was a associate vice chair of Neurology at the David primary research interest is self-care of older post-doctoral fellow in Clinical Chemistry at the Geffen School of Medicine, University of Califor- adults with chronic heart failure. Recently, her Mayo Clinic and has ABCC Board certification as nia, Los Angeles. Dr. Saver received his medical interests have expanded to include multimorbid- a clinical chemist. degree from Harvard Medical School in 1981, and ity — a common phenomenon in adults with In the mid-1980s, Dr. Tracy began work in is a graduate of the Harvard-Longwood Neurol- heart failure. Dr. Riegel focuses her research on cardiovascular clinical trials, and in the late 1980s ogy Training Program, the University of Iowa the self-care issues of medication adherence and added epidemiological science, which has become Fellowship Program in Behavioral Neurology and decision-making in response to symptoms. She his major area of interest. Dr. Tracy’s research Cognitive Neuroscience and the Brown University has demonstrated that poor medication adherence focuses on coagulation, inflammation and adap- Fellowship Program in Vascular Neurology. An au- is a primary contributor to hospitalization in heart tive immune systems in cardiovascular disease thor or co-author of more than 470 research articles, failure, identified intentional and unintentional and other chronic diseases. He has made major two books and 35 book chapters, Dr. Saver’s re- factors associated with poor medication adher- contributions to our understanding of inflamma- search interests are in acute stroke treatment, stroke ence and developed an approach to improving tion in atherosclerosis and as a major cause of prevention, neuroimaging, clinical trial design and medication adherence in these patients. CVD and non-CVD morbidity and mortality in neurocognitive consequences of stroke. In reference to symptom response, she “well-controlled” HIV-infected individuals. Most Dr. Saver has held numerous leadership positions has identified factors that impair the ability of recently, his lab has focused on the role of chronic in neurovascular and translational science organiza- heart failure patients to accurately perceive and infections, including CMV, HIV and HCV, in the tions, including having served as chair of the AHA/ interpret their symptoms, including age-related regulation of adaptive immunity, and the implica- ASA Stroke Council, founding chair of the AHA/ changes in interoception and illness-related tions for CVD. ASA Stroke Scientific Statements Oversight Com- changes in the brain. She has published both a NIH funded since 1984, Dr. Tracy is involved mittee, founding chair of the AHA/ASA Stroke situation-specific theory of heart failure self-care in many molecular and genetic epidemiological Performance Measures Oversight Committee, and a middle range theory of self-care of chronic studies often as core lab director, biorepository co-chair of the NIH-NINDS Common Data Ele- illness. These theories have formed the basis director, and/or Steering Committee; examples in- ments — Stroke Task Force, principal investigator of various self-report research measures used clude the Cardiovascular Health Study, the Multi- of the NIH-NINDS Field Administration of Stroke worldwide to study the self-care behaviors of Ethnic Study of Atherosclerosis, the NHLBI Heart Magnesium (FAST-MAG) phase 3 clinical trial, prin- chronically ill individuals. Failure Network, NHLBI’s HIV-CVD Consor- cipal investigator of NIH-NINDS UCLA Specialized Dr. Riegel has more than 250 peer-reviewed tium, and NHLBI’s Exome Sequencing Program. Program of Translational Research in Acute Stroke publications and is invited to speak nationally The LCBR Biological Specimen Repository is a (SPOTRIAS) and global principal investigator of the and internationally on self-care. This interest major national resource, currently housing >4M Solitaire with the Intention for Thrombectomy as grew out of her early years as a clinical nurse samples, in almost 200 ultracold freezers. Primary Endovascular Treatment for Acute Ischemic researcher at Sharp HealthCare in San Diego, Dr. Tracy has more than 600 scientific Stroke (SWIFT PRIME) pivotal clinical trial. Having where she led several studies testing disease publications and numerous honors, including C O served on the editorial boards of numerous journals, management approaches to transitioning chroni- the American Association of Clinical Chemistry N he is currently associate editor at JAMA, the Journal cally ill patients from hospital to home, a theme Bernie Zak Award for Research, the University of N E of the American Medical Association, as well as that continues in her current program of research. Oklahoma Kelly West Lecturer, Emory University C consulting editor at the journal Stroke. Distinguished Visiting Professor in Pathology and T IO Russell P. Tracy, PhD, University of Kentucky Gill Heart Institute Visit- N Barbara J. Riegel, PhD, FAHA ing Professor. He serves currently on the Office S RN, FAHA Professor of Pathology & of AIDS Research Working Group on HIV and F A Edith Clemmer Steinbright Laboratory Medicine and Aging, and has participated in many NHLBI, NIA L L Professor of Gerontology Biochemistry and NIAID workshops and planning sessions. He 2 School of Nursing Director, Laboratory for Clin- has done extensive mentoring of graduate students, 0 1 University of Pennsylvania ical Biochemistry Research postdoctoral fellows and junior faculty and has 5 Philadelphia University of Vermont College of Medicine served on the advisory boards of several training Barbara Riegel is the Edith Clemmer Stein- Burlington, Vermont programs around the country. my.americanheart.org 7 Councils: Year In Review The AHA’s 16 Scientific Councils Basic Cardiovascular Sciences underrepresented medical students, [and] are members from multiple, July 2014 marked the 10th anniversary of the addressing the needs of underserved specific disciplines that support Basic Cardiovascular Sciences Scientific Ses- communities.” The intent of CVRI’s outreach AHA’s mission and serve as a robust sions, which has increased attendance every is to further promote careers in cardiovascular group of scientific experts for the AHA. year. In 2014, the conference welcomed 600 imaging to physicians from underrepresented They make essential contributions to the attendees from 22 countries. populations, which is also in line with the AHA scientific and administrative goals of the The Kenneth D. Bloch Memorial mission. Garth Beache, MD, led the develop- AHA by creating the programming for all of Lecture in Vascular Biology was established ment of co-sponsored sessions on cardiovascu- AHA’s scientific meetings and professional to honor the life and work of Kenneth Bloch, lar imaging for the Student National Medical education offerings; authoring Guidelines on MD. It is co-sponsored by BCVS and the Association (SNMA) annual meeting in early Practice and scientific statements that provide Council on Cardiopulmonary, Critical Care, 2015. This successful relationship with the review and understanding of many science Perioperative and Resuscitation (3CPR). Ste- SNMA was identified as a best practice during topics; serving as peer reviewers for AHA phen Archer, MD, was selected as the inaugural CVRI’s Council Biennial review by the Council grants, scientific journals, conference Bloch lecturer. Operations Committee. abstracts and other AHA initiatives; and serving as expert representatives for the Cardiovascular Disease in the Young Cardiovascular Surgery and Anesthesia AHA on many national and international The council on Cardiovascular Disease in The Council on Cardiovascular Surgery and committees and groups. the Young (CVDY) has planned a new Anesthesia (CVSA) launched a new Mentoring special focus track, Lifelong Congenital Program to support and help early career Council Accomplishments 2014-15 Heart Disease and Heart Health in the Young, members develop their professional careers. which will debut at 2015 Scientific Sessions to Mentees will be matched with a senior Cardiopulmonary, Critical Care, cover the latest findings relating to congenital volunteer mentor and a volunteer peer mentor Perioperative and Resuscitation heart defects and the prevention of with expertise in their field. In an important The Council on Cardiopulmonary, Critical cardiovascular diseases starting in childhood. advance in multidisciplinary collaboration, Care, Perioperative and Resuscitation (3CPR), It also will focus not only on congenital/ CVSA joined the SCA’s Clinical Practice and in collaboration with the Council on Basic structural heart disease, but acquired Quality Improvement Initiative in Cardiac Cardiovascular Sciences (BCVS), established cardiovascular diseases as well. Surgery. The project is a multidisciplinary the Kenneth D. Bloch Memorial Lecture in collaboration of physicians and healthcare Vascular Biology to honor Dr. Kenneth D. Cardiovascular Radiology and workers that includes and embraces many Bloch, a pioneer in the governance and leader- Intervention AHA surgeons and cardiologist members, as ship of American Heart Association over many The Council on Cardiovascular Radiology and well as members of the STS and Heart Rhythm years. The award will be presented at Scientific Intervention (CVRI) once again supported the Society. Sessions 2015. 42nd Annual Meeting of the North American Past Council Chair Frank Sellke, MD, Society for Cardiovascular Imaging in Septem- FAHA, was appointed as Chair of the AHA’s Arteriosclerosis, Thrombosis and ber 2014 in New Orleans. The program included Committee on Scientific Sessions Program. 5 Vascular Biology the presentation of the AHA CVRI Young Under Dr. Sellke’s leadership, exciting 1 0 The Arteriosclerosis, Thrombosis and Vascular Investigator Awards to Akos Varga-Szemes, changes have been made to Scientific Sessions’ 2 Biology/Peripheral Vascular Disease 2015 MD, PhD; Kate Hanneman, MD; and Akif structure, and new topics have been added to L L Scientific Sessions was organized in Mohammed, MD. increase the educational offerings available to A F collaboration with the Council on Functional For the 2014 Scientific Sessions, Harold attendees. S Genomics and Translational Biology (FGTB) Litt, MD, led the Cardiac Imaging Boot Camp Past AHA President and CVSA Chair Tim N and the Society for Vascular Surgery. Its to kick off CVRI’s early career program, Gardner, MD, FAHA, was awarded the Chair- O TI primary goal is to serve as the principal introducing a new format focused on case-based man’s Award. Dr. Gardner has been a force in C E venue for presenting preclinical, clinical imaging by modality. Also at Sessions, CVRI fostering the advancement of education and N and population-based research that drives new was honored to have Joao Lima, MD, present quality assessment in surgery, including playing N O insights and provides new directions for the the Charles T. Dotter Memorial Lecture. a critical role at the National Institutes of Health C prevention and management in the fields of CVRI also continued its support of the in the establishment of the NIH Cardiothoracic arteriosclerosis, thrombosis and vascular Student National Medical Association, which Surgical Trials Network. biology as well as vascular medicine. is “committed to supporting current and future CVSA was recognized as the Council 8 my.americanheart.org Operations Committee Council Engagement Prevention Science Subcommittee; EPI and as it has been for many years. Winner in the medium council category. QCOR Social Determinants of Health Science The Trainee Advocacy Committee Subcommittee; and EPI and FGTB Molecular developed the Council on Hypertension Cardiovascular and Stroke Nursing Determinants of Cardiovascular Health Com- Mentoring Program (CHAMP), whose mission The Council on Cardiovascular and Stroke mittee. In addition, the EPI the Functional Ge- statement is to foster an environment of Nursing member, Barbara Riegel, PhD, FAHA, nomics and Epidemiology Mid-Career Research training and networking activities in order FAAN, was awarded the Distinguished Scientist Award and Lecture Council was established to provide support in the form of mentor Designation and will be recognized at Scientific between the two councils.. CHAMPions for future career choices in Sessions 2015. Dr. Riegel is the Edith Clemmer Once again, the councils was recognized the scientific community. The matched Steinbright Professor of Gerontology and the by the Council Operations Committee as a mentors/mentees met for the first time at the Director of the Biobehavioral Research Center Council Engagement Winner in the large Council on Hypertension Scientific Sessions at the University of Pennsylvania. This is only council category. in September. the second time a nurse has been awarded the John Hall, MD, FAHA, was awarded the Distinguished Scientist Designation. Functional Genomics and Translational American Heart Association’s Meritorious The Council developed both a Diversity Biology Achievement Award for his many scientific Task Force and a Doctor of Nursing Practice The Council on Functional Genomics and contributions. For more than 30 years, he has (DNP) Toolkit resource this year. The Diversity Translational Biology planned an active served as a leader of the AHA’s Council on Task Force is dedicated to increasing diversity learning, “flipped classroom” approach dur- Hypertension, including serving as a major within the Council and the Council’s commit- ing ATVB/PVD 2015. The Boot Camp was a participant in national AHA committees and tees and inviting people from diverse groups to two-hour session that focused on two topics: policymaking and as editor-in-chief of the jour- Scientific Sessions. The DNP Task Force will genome editing with the CRISPR-Cas9 system nal Hypertension. develop a DNP resource center on the AHA and use of ENCODE data. At the Boot Camp, Professional Membership website. roughly 100 participants, made up of conference Kidney in Cardiovascular Disease attendees, formed groups of about three to four The Council on Kidney in Cardiovascular Clinical Cardiology people to work through two cases related to the Disease continued its support of the The Council on Clinical Cardiology and the featured technologies. Nine instructors drawn APS-Renal Section Poster and Professors Cardiac Arrhythmia Research Summit brought from the Early Career memberships of the Session at the Experimental Biology 2015 together international experts in cardiac electro- FGTB and ATVB Councils circulated around (EB15) meeting in Boston. physiology in an exciting one-day symposium. the Boot Camp to give guidance and answer In November, the council had its annual It was held on Nov. 19, 2014, in coordination questions from the groups. Young Investigator Symposium and Reception with Scientific Sessions in Chicago. In addition, the Council: at ASN’s Kidney Week in Philadelphia. Also at Sessions, the Council on Clinical • Established the Functional Genomics and KCVD once again co-sponsored the ASN Cardiology hosted its third High School Minor- Epidemiology Mid-Career Research Award Young Investigator Award with ASN for Kidney ity Outreach Program and doubled attendance to and Lecture Week 2014. Special thanks go to the KCVD 86 students from 14 different high schools in the • Established the Molecular Determinants in Early Career Committee for their hard work Chicago area. A special highlight of the day was Health Committee in conjunction with the and dedication during the planning of the Young training every student in hands-only CPR, as Council on Epidemiology and Prevention. Investigator Symposium. well as the provision of inflatable mannequins • Established a new process for recruiting that they could take home to demonstrate CPR members through the Early Career Committee. Lifestyle and Cardiometabolic Health to friends and family. • Obtained CME accreditation for the Basic The Council on Lifestyle and Cardiometa- Council members were acknowledged with Concepts in Genetics and Genomics Modules. bolic Health along with the Epidemiology and C O national AHA Awards for their service and • Was once again recognized by the Council Op- Prevention renamed their annual convention N volunteerism: erations Committee as a Council Engagement in 2015. The EPI/NPAM Conference was re- N E • Clinical Research Prize: Judith Hochman, MD Winner in the small council category. named to the EPI/Lifestyle 2015 Scientific Ses- C • Chairman’s Award: Jennifer Mieres, MD, sions. The conference continues to grow each T IO FAHA Hypertension year and is a premier function of the Lifestyle N • Gold Heart Award: Clyde Yancy, MD, FAHA The Council on High Blood Pressure changed and Cardiometabolic Health Council. S its name to the Council on Hypertension in Early Career Committee activities have F A Epidemiology and Prevention order to broaden its scope to encompass the been prominent at the conference, including L L The Council on Epidemiology and Prevention larger field of hypertension, which includes the Lifestyle Council Annual Business 2 continues cross-collaboration with other both research and clinical specialties. The Meeting and Networking luncheon, several 0 1 Councils through its joint science subcommittees 2015 conference, the Council on Hypertension lunchtime sessions and roundtable sessions 5 such as EPI and Lifestyle Behavior Change Scientific Sessions, was co-sponsored by the held by senior investigators for early career Science Subcommittee; EPI and CVSN Council on Kidney in Cardiovascular Disease, see REVIEW, page 13 my.americanheart.org 9 Research Networks Update the disproportionate impact of cardiovascular diseases and stroke in some population groups. In June, the AHA announced the four insti- receive a total of $15 million, and each center Each center will train three fellows, and all tutions that will form the American Heart will undertake three research projects focused four centers will meet on a regular basis and Association Strategically Focused Dis- on factors — such as socioeconomic status engage in collaborative projects to accelerate parities in Cardiovascular Disease and Stroke and genetic risk profile — that may underlie information exchange and ideas. Research Network: the Medical University of South Carolina (Director: Robert Adams, MD, MS), Morehouse School of Medicine (Direc- tor: Herman Taylor, Jr., MD, MPH), North- western University (Director: Myles Wolf, MD, MMSc), and the University of Colorado, Denver (Director: Spero Manson, MD). Over the next four years, these centers will Gold Standard Boards Twenty-four local governing bodies of the American Heart Association can call themselves Gold Standard Boards for meeting criteria designed to help strengthen and improve health, revenue and volunteerism goals at AHA affiliates across the country. Another 24 local boards, out of 104 nationwide, have earned the Silver Standard Board designation, and 35 are Bronze Standard Boards. Among the criteria used to determine award Notable achievements from the current and active AHA/ASA Professional Members winners is a board’s composition. The AHA year’s results include: who served as president of the following suggests boards include at least 25 percent physi- • Twin Cities (MWA) is the only division to boards recognized as Gold and Silver during cians or medical professionals; 25 percent mem- achieve Gold status in all four years; its the 2014-2015 fiscal year: bers such as philanthropists, survivors of heart revenue growth over this time has been 38 disease or stroke, or members of health-related percent. Gold companies; and 50 percent from the corporate • The Kansas City division (MWA) and Lou- Michael Artman, FAHA world. Typically, board presidents are physicians isville division (GRA) have both been at the Kansas City, Missouri who can serve as spokespeople for the AHA, Gold award level for three years running. Sub- Thomas Barringer, MD while chairs are from the corporate world. sequently their three-year growth rates have Charlotte, North Carolina 5 To achieve the Gold Standard designation, been 58 percent and 17 percent, respectively. Thomas Broderick, MD, FAHA 1 0 a local board has to meet 14 of the 16 criteria • Ninety-three percent of board members Cincinnati 2 established by the AHA. That shows they are around the country participated in at least Angela Brown, MD L L following the best practices to generate rev- one AHA/ASA health activity in their com- St. Louis A F enue, sustain volunteer leadership and achieve munities last year. Joshua Buckler, MD, FAHA S the AHA mission of making a health impact in • Sixty-four percent of the Top 25 compa- Puget Sound (Seattle), Washington N O the local community. nies in each division around the country Vincent Figueredo, MD, FAHA TI The Gold Standards Board initiative began participated in at least one AHA/ASA health Philadelphia C E four years ago to help dramatically ramp up activity. Christopher Granger, MD, FAHA N volunteer efforts to meet the AHA’s 2020 Science professionals play a significant role Durham, North Carolina N O Impact Goal “to improve the cardiovascular in strengthening these local boards through re- Steven Raible, MD C health of all Americans by 20 percent while cruitment and engagement efforts, community Louisville, Kentucky reducing deaths from cardiovascular diseases involvement and advocacy efforts. Congratula- Robert Spicer, MD and stroke by 20 percent.” tions to these outstanding science volunteers Omaha, Nebraska 10 my.americanheart.org

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Arteriosclerosis, Vascular Biology and Devel- · opment . questions answered in a casual setting. University of Vermont College of Medicine.
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