Subject index of volume 109 Abecarnil 163 Ca?* channel inhibitors 12 D.-dopamine receptors 410 Acetylcholine 439 Cerebral hypoxic hypoxidosis 30 Active avoidance conditioning 157 Cerebral ischemia 264 Eating 331 Acute ethanol withdrawal 112 Cerebrospinal fluid 497 EEG 163, 277, 283 Acute tolerance 107 CGP 37849 383 EEG mapping 30 Adenosine triphosphate (ATP) -sensitive Chlordiazepoxide 177, 203, 433, 461 Elevated X-maze 338 potassium (Karp) channels 239 Choice 245 Elimination rate 449 Adenylate cyclase 231 Cholinergic 299 Enkephalins 347 Adrenalectomy 299 Cholinergic system 127, 373 Ethanol 107, 112, 217 Adverse side-effects 484 Circumventricular organs 347 Ethanol self-administration 92 Aging 127, 489 Classical conditioning 185 Ethanolamine O-sulphate 191 Alcohol intake 191 Clinical effects 145 Excitatory amino acids 271 Alpha-2 adrenoceptors 127, 271 Clonidine 235 Excitotoxic lesion 331 Amino acids 251 Clozapine 473 Exercise 77 Amount of reinforcement 245 Co-administration of drugs 99 Exploratory 315 Amperozide 473 Cocaine 99, 241, 245, 305 Amphetamine 63, 99, 331, 415 Co-dergocrine mesylate 30 F 2692 338 Analgesia 291 Coffee 85 Feeding 212, 403 Anhedonia 305 Compensatory behaviors 112 Fenfluramine 331, 415 Anorectics 415 Competitive antagonism 291 Fenoldopam 41 Anorexia 77, 331 Concurrent schedules 85 Fentanyl 291 Anticonvulsant 107 Conditioned avoidance response 134 FG 7142 379 Anticonvulsant effect 12 Conditioned tolerance 217 Flesinoxan 395 Antidepressant 231 Conditioning 172 Flumazenil 315 Antidepressant activity 369 Consumption history 121 Fluoxetine 2, 212, 245, 415, 433 Antidepressant effect 12 Contingent tolerance 217 Fluvoxamine 395 Antidepressive agents, tricyclic 57 Corticosteroids 383 Food intake 77, 415 Antidopaminergic effect 12 Corticosterone 299 Food-deprived 444 Antihypertensive agents 484 Corticotropin-releasing factor 177 Footshock 395 Anxiety 153, 395 C57BL/6 mice 457 Full and partial agonists 365 Anxiogenic drugs 379 Anxiolytic 315 Dark adaptation 68 Anxiolytic effect 12 Delay of reinforcement 245 GABA 68 Apomorphine 49, 390 Delayed match-to-sample 439 GABA transmission 163 Associative 185 Delayed neuronal death 264 GABA, receptors 191 Atenolol 484 Delta receptor 157 Gerontopsychopharmacology 30 Atropine 68 Dependence 449 GM1 457 Attention 203 Depression 305, 395 Grooming 41 Atypical antidepressants 2 Desipramine 305 Autonomic systems 347 Desmethylimipramine 305, 395 Haloperidol 63, 248, 477 Development 191, 457 Heart 57 Baboons 484 Dexfenfluramine 212 a-Helical CRFg_4, 177 Behavior 255, 403 Diazepam 338, 395 Hippocampus 373 Behavioral tolerance 217 Diet composition 212 Holeboard test 315 Behaviour 277, 395 Dietary self-selection 177 HPNS 163 Behavioural observations 163 1,4-Dihydropyridines 12 5-HT-receptor antagonists 466 Benzodiazepine receptors 365 Dissociative anaesthesia 271 5-HT 77, 338 Benzodiazepines 68, 153, 461 DMI 305 5-HT agonists 77 Beta-adrenergic blocking agents 484 Dopamine 68, 369, 379, 390, 403 5-HT receptors 77 Beta-adrenergic receptors 305 Dopamine antagonist 92 5-HT release 251 Beta-CCE 379 Dopamine receptors 49 5-HT synthesis 251 Bicuculline 68 Dose-response curves 172, 185 5-HT uptake inhibitors 2 Blood brain barrier 497 Dose-response effect 457 5-HT.2-receptors 473 Blood gases 30 Downregulation 305 5-HT2 antagonists 2 Blood-brain barrier 347 Drug abuse 305 5-HT3 antagonists 461 Body temperature 217, 365 Drug discrimination 63, 99, 291 5-HT,¢ receptors 77 Brain protection 30 Drug self-administration 85 Human 68, 231 Brain stimulation reward 305 Drug-induced reinforcement 12 Human brain 410 Bungarotoxin 299 403 Humans 85 dopamine agonists 241 5-Hydroxyindoleacetic acid 422 Caffeine 85, 99, 121, 283 receptor 477 Hydroxylation 57 Captopril 383 receptors 41 5-Hydroxy-tryptophan 422 Carbohydrate 212, 415 403 Hyperactivity 77 Cat 68 receptor 477 Hyperthermia 239, 466 Catalepsy 477 receptors 41 Hypothermia 217 Subject index of volume 109 Abecarnil 163 Ca?* channel inhibitors 12 D.-dopamine receptors 410 Acetylcholine 439 Cerebral hypoxic hypoxidosis 30 Active avoidance conditioning 157 Cerebral ischemia 264 Eating 331 Acute ethanol withdrawal 112 Cerebrospinal fluid 497 EEG 163, 277, 283 Acute tolerance 107 CGP 37849 383 EEG mapping 30 Adenosine triphosphate (ATP) -sensitive Chlordiazepoxide 177, 203, 433, 461 Elevated X-maze 338 potassium (Karp) channels 239 Choice 245 Elimination rate 449 Adenylate cyclase 231 Cholinergic 299 Enkephalins 347 Adrenalectomy 299 Cholinergic system 127, 373 Ethanol 107, 112, 217 Adverse side-effects 484 Circumventricular organs 347 Ethanol self-administration 92 Aging 127, 489 Classical conditioning 185 Ethanolamine O-sulphate 191 Alcohol intake 191 Clinical effects 145 Excitatory amino acids 271 Alpha-2 adrenoceptors 127, 271 Clonidine 235 Excitotoxic lesion 331 Amino acids 251 Clozapine 473 Exercise 77 Amount of reinforcement 245 Co-administration of drugs 99 Exploratory 315 Amperozide 473 Cocaine 99, 241, 245, 305 Amphetamine 63, 99, 331, 415 Co-dergocrine mesylate 30 F 2692 338 Analgesia 291 Coffee 85 Feeding 212, 403 Anhedonia 305 Compensatory behaviors 112 Fenfluramine 331, 415 Anorectics 415 Competitive antagonism 291 Fenoldopam 41 Anorexia 77, 331 Concurrent schedules 85 Fentanyl 291 Anticonvulsant 107 Conditioned avoidance response 134 FG 7142 379 Anticonvulsant effect 12 Conditioned tolerance 217 Flesinoxan 395 Antidepressant 231 Conditioning 172 Flumazenil 315 Antidepressant activity 369 Consumption history 121 Fluoxetine 2, 212, 245, 415, 433 Antidepressant effect 12 Contingent tolerance 217 Fluvoxamine 395 Antidepressive agents, tricyclic 57 Corticosteroids 383 Food intake 77, 415 Antidopaminergic effect 12 Corticosterone 299 Food-deprived 444 Antihypertensive agents 484 Corticotropin-releasing factor 177 Footshock 395 Anxiety 153, 395 C57BL/6 mice 457 Full and partial agonists 365 Anxiogenic drugs 379 Anxiolytic 315 Dark adaptation 68 Anxiolytic effect 12 Delay of reinforcement 245 GABA 68 Apomorphine 49, 390 Delayed match-to-sample 439 GABA transmission 163 Associative 185 Delayed neuronal death 264 GABA, receptors 191 Atenolol 484 Delta receptor 157 Gerontopsychopharmacology 30 Atropine 68 Dependence 449 GM1 457 Attention 203 Depression 305, 395 Grooming 41 Atypical antidepressants 2 Desipramine 305 Autonomic systems 347 Desmethylimipramine 305, 395 Haloperidol 63, 248, 477 Development 191, 457 Heart 57 Baboons 484 Dexfenfluramine 212 a-Helical CRFg_4, 177 Behavior 255, 403 Diazepam 338, 395 Hippocampus 373 Behavioral tolerance 217 Diet composition 212 Holeboard test 315 Behaviour 277, 395 Dietary self-selection 177 HPNS 163 Behavioural observations 163 1,4-Dihydropyridines 12 5-HT-receptor antagonists 466 Benzodiazepine receptors 365 Dissociative anaesthesia 271 5-HT 77, 338 Benzodiazepines 68, 153, 461 DMI 305 5-HT agonists 77 Beta-adrenergic blocking agents 484 Dopamine 68, 369, 379, 390, 403 5-HT receptors 77 Beta-adrenergic receptors 305 Dopamine antagonist 92 5-HT release 251 Beta-CCE 379 Dopamine receptors 49 5-HT synthesis 251 Bicuculline 68 Dose-response curves 172, 185 5-HT uptake inhibitors 2 Blood brain barrier 497 Dose-response effect 457 5-HT.2-receptors 473 Blood gases 30 Downregulation 305 5-HT2 antagonists 2 Blood-brain barrier 347 Drug abuse 305 5-HT3 antagonists 461 Body temperature 217, 365 Drug discrimination 63, 99, 291 5-HT,¢ receptors 77 Brain protection 30 Drug self-administration 85 Human 68, 231 Brain stimulation reward 305 Drug-induced reinforcement 12 Human brain 410 Bungarotoxin 299 403 Humans 85 dopamine agonists 241 5-Hydroxyindoleacetic acid 422 Caffeine 85, 99, 121, 283 receptor 477 Hydroxylation 57 Captopril 383 receptors 41 5-Hydroxy-tryptophan 422 Carbohydrate 212, 415 403 Hyperactivity 77 Cat 68 receptor 477 Hyperthermia 239, 466 Catalepsy 477 receptors 41 Hypothermia 217 Imipramine 57 Noradrenaline 235 SCH 23390 41, 49, 403, 477 Indoleacetic acid 422 Noradrenergic system 127 Schizophrenic suicides 410 Ingestion rate 415 Norepinephrine 415 Scopolamine 223, 321, 373 Inhibitory avoidance 457 Nucleus accumbens 92, 379 Seizures 365 Intoxicated practice 112 Selective agonists 157 Intracranial self-stimulation 305 Object-recognition 321 Selective antagonists 157 Inverse agonists 365 Ocular effects 255 Self administration 241, 291 Ipsapirone 338 8-OH-DPAT 134 Self-administration 305 Olfaction 439 Self-control 245 Ketanserin and mianserin 264 Ondansetron 461, 497 Sensory imbalance 390 Kynurenine 422 Operant behavioural dependence 461 Sensory responsiveness 390 Operant performance 112 Serotonin 2, 77, 415, 422 Large neutral amino acids 422 Operant schedule 217 Shift effect 68 Lateral hypothalamus 331 Opiate-withdrawal 235 Short-term memory 127, 439 Learning 157, 347, 373 Opioid 291 Side-effects 377 Lever press 145 Opioid peptides 157 SKF 38393 41, 241, 403 Levodopa 68 Opioid receptors 157 SKF 77434 403 . Light-dark exploratory test 315 Organogenesis 255 SKF 82958 403 Lithium 231 Oxytocin levels 473 Spatial alteration behavior 223 Locomotor 315 Spatial discrimination 373 Spiperone 403, 444 Pavlovian conditioning 217 Maprotiline 433 Squirrel monkeys 241 PEP 277 Marmosets 49 Starvation 77 PCP psychosis 271 Matching law 145 State-dependence 321 Pentabarbitone 99 mCPP 77, 466 Stimulants 305 Performance 121, 489 MDL-72222 444 Stimulus encoding 198 Perphenazine 477 Melatonin 422 Strain differences in mice 365 Personality 283 Memory 347, 489 Stress 77, 299, 379, 395, 433 Pharmacodynamics 449 Memory facilitation 383 Stress coping 283 Pharmacokinetics 57, 449 Memory inhibition 383 Stress proneness 283 Phenylpropanolamine 99, 415 Memory scanning 198 Strychnine 383 Phosphoinositide turnover 248 Men 422 Subthreshold summation 68 Physiology 283 Mental effort 489 Sucrose drinking 433 Physostigmine 198, 321 Mental performance 283 Sugars 415 Place preference conditioning 433 Mesolimbic system 369 Sulpiride 68 Plasma concentrations 422 Mesulergine 444 Supersensitivity 63 Plasma GABA 153 Metergoline 444 Swine 57 Platelet 231 Methamphetamine 255 Synergism 41 Postnatal 191 Methodology 85 Methylphenidate 145 Primates 163 Tail pinch 331 Mianserin 444 Propranolol 444, 484 Tailflick 172, 185 Mice 157, 315, 383 Protein 177 TFMPP 466 Microdialysis 235, 338, 379 Psychometry 30 Thresholds 305 Microstructure of ingestion 415 Psychophysics 68 Time of day 121 Midazolam 203 Pupil size 489 Tolerance 63, 112, 172, 185, 299, 449 MK-801 477 Tolerance retention 185 Modulation 347 Quinpirole 49 Trazdone 2 Mongolian gerbil 264 Tricyclic antidepressants 305 Mood 489 Raclopride 49 Tryptophan metabolites 422 Morphine 99, 172, 185, 239 [*H]raclopride 410 L-tryptophan 251, 422 Motor impairment 107 Radial-maze 321 Turning behavior 390 Motor performance 145 Rat 127, 134, 145, 177, 191, 255, 338, Uric acid 377 Mu receptor 157 369, 373, 395, 403 Uricosuric agents 377 Muscarinic receptor 248 Rate dependency principle 145 Rats 217, 245, 277, 321, 433, 461 L-valine 251 N-Acetyl-tryptophan 422 Receptors 299 Variable-interval schedule 145 Neophilia 177 Rehearsal 223 Ventral hippocampus 338 Neuroleptics 377 Reinforcement 85, 241 Vigilance 203 Neurotensin 369 Reinforcement efficacy 145 Visual receptive fields 68 Nicotine 248, 299, 449 Renovascular hypertension 484 Visual system 68 Nicotinic 299 Reserpine 271 Vitamin B-6 489 Nifedipine 235 Respiratory function 291 Nimodipine 383 Response rate 145 Withdrawal 63, 305, 461 Nitrous oxide 315 Response strength equation 145 Working memory 223 NMDA 277 Restraint stress 177 Working-memory 321 NMDA antagonist 92 Reward 433 Nonassociative 185 Rhesus monkey 291 Yohimbine 271 Non-compliance 377 Ritanserin 444 Non-human primates 484 Ro15-1788 203 ZK 91296 203 Nootropics 30 RU 24969 212 Zuclopenthixol 377