TABLE OF CONTENTS Autonomic pharmacology RELATIONSHIP BETWEEN THE NICOTINIC CHOLINERGIC MEDIATED INDUCTION OF TYROSINE HYDROXYLASE AND RELEASE OF CATECHOLAMINES IN BOVINE ADRENAL CHROMAFFIN CELLS G.L. Craviso, V.B. Hemelt, J.C. Waymire, J. Larsen, S.T. Mihaylova-Todorova, D.P. Westfall & R.A. Bjur CATECHOLAMINERGIC ACTION OF JUDAS GUT ALCOHOLIC EXTRACT ON AORTIC RINGS FROM THE GUINEA PIG E. Gijon, M. Lorenzana, L. Cartas & X. Garcia CHARACTERIZATION OF THE a-ADRENERGIC EFFECT OF SOME 5-HT) , AGONISTS E. Hong, C. Castillo, M. Ibarra & R. Villalobos PURINERGIC FACILITATION OF NOREPINEPHRINE RELEASE FROM ADRENERGIC NERVES OF RABBIT EAR ARTERY R. Ishii, K. Shinozuka, K. Hattori, R.A. Bjur, D.P. Westfall, K. Takeuchi & T. Hashimoto DIFFERENTIATION OF PC 12 CELLS INDUCED BY INHIBITION OF N®.ACETYLSPERMIDINE DEACETYLASE USING 7-(N-(3-AMINO- PROPYL)AMINO]JHEPTAN-2-ONE A.M.S. Menezes & J. Blankenship Cardiovascular pharmacology NONPEPTIDE ANGIOTENSIN II RECEPTOR ANTAGONISTS: POTENTIAL ADVANTAGES OVER ACE INHIBITORS D.P. Brooks, P.D. Depalma, T.A. Fredrickson RINE, NNN TR. sssacanvanssnsdunvacnanenubectannsianassncnancnbedsleunnnicaaeecasied 25 NONSPECIFIC ANTISPASMODIC ACTION OF VIGUIEPINOL V. Campos-Lozada, E. Campos, C. Guerrero J. Taboada, J. Hernandez-Falcon & B. Fuentes-Pardo EFFECT OF CHRONIC COCAINE ON CARDIOVASCULAR RESPONSES TO . NOREPINEPHRINE AND ACETYLCHOLINE IN THE CONSCIOUS RAT W.R. Dixon, A. Chang, E. Judd, H. Carrillo & H. Simms TABLE OF CONTENTS Autonomic pharmacology RELATIONSHIP BETWEEN THE NICOTINIC CHOLINERGIC MEDIATED INDUCTION OF TYROSINE HYDROXYLASE AND RELEASE OF CATECHOLAMINES IN BOVINE ADRENAL CHROMAFFIN CELLS G.L. Craviso, V.B. Hemelt, J.C. Waymire, J. Larsen, S.T. Mihaylova-Todorova, D.P. Westfall & R.A. Bjur CATECHOLAMINERGIC ACTION OF JUDAS GUT ALCOHOLIC EXTRACT ON AORTIC RINGS FROM THE GUINEA PIG E. Gijon, M. Lorenzana, L. Cartas & X. Garcia CHARACTERIZATION OF THE a-ADRENERGIC EFFECT OF SOME 5-HT) , AGONISTS E. Hong, C. Castillo, M. Ibarra & R. Villalobos PURINERGIC FACILITATION OF NOREPINEPHRINE RELEASE FROM ADRENERGIC NERVES OF RABBIT EAR ARTERY R. Ishii, K. Shinozuka, K. Hattori, R.A. Bjur, D.P. Westfall, K. Takeuchi & T. Hashimoto DIFFERENTIATION OF PC 12 CELLS INDUCED BY INHIBITION OF N®.ACETYLSPERMIDINE DEACETYLASE USING 7-(N-(3-AMINO- PROPYL)AMINO]JHEPTAN-2-ONE A.M.S. Menezes & J. Blankenship Cardiovascular pharmacology NONPEPTIDE ANGIOTENSIN II RECEPTOR ANTAGONISTS: POTENTIAL ADVANTAGES OVER ACE INHIBITORS D.P. Brooks, P.D. Depalma, T.A. Fredrickson RINE, NNN TR. sssacanvanssnsdunvacnanenubectannsianassncnancnbedsleunnnicaaeecasied 25 NONSPECIFIC ANTISPASMODIC ACTION OF VIGUIEPINOL V. Campos-Lozada, E. Campos, C. Guerrero J. Taboada, J. Hernandez-Falcon & B. Fuentes-Pardo EFFECT OF CHRONIC COCAINE ON CARDIOVASCULAR RESPONSES TO . NOREPINEPHRINE AND ACETYLCHOLINE IN THE CONSCIOUS RAT W.R. Dixon, A. Chang, E. Judd, H. Carrillo & H. Simms NICARDIPINE OR PROPRANOLOL COMBINED WITH HYDROCHLOROTHIAZIDE IN PATIENTS WITH ESSENTIAL HYPERTENSION J. Arriaga-Gracia, J. L. Sanchez-Garcia & C. A. Gonzdlez-Garcia EFFECTS OF OXYGEN DEPRIVATION ON CARDIAC REDOX SYSTEMS J.P. Kehrer, T. Paraidathathu & L.G. Lund THE CARDIOVASCULAR EFFECTS OF PROTAMINE IN RATS AND ISOLATED RAT HEART R. Kertesz & M.J.A. Walker ADENOSINE INCREASES BLOOD LACTATE PRODUCTION IN THE ANESTHETIZED RAT Y. Zhang & W.W. Lautt DEVELOPMENTAL CONTRACTILITY CHANGES IN OVINE PERIPHERAL CEREBRAL ARTERIES S.R. Elliott & W.J. Pearce MATURATION AND HYPOXIA INFLUENCE THE CALCIUM DOSE RESPONSE RELATIONSHIP IN OVINE CEREBRAL ARTERIES S.D. Zurcher & W.J. Pearce NEUROPEPTIDE EFFECTS ON CARDIAC REFLEXES IN THE CONSCIOUS DOG D.V. Priola & X. Cao MODULATION OF VASCULAR REACTIVITY BY ENDOTHELIUM DERIVED FACTORS COMPARISON OF ENDOGENOUS ADENYL PURINE RELEASE FROM AORTA AND CAUDAL ARTERY OF RAT K. Shinozuka, Y. Tanabe, Y. Kobayashi, K. Shimoura, S. Takaori, K. Takeuchi, R.A. Bjur, D.P. Westfall & K. Hattori ANTIARRHYTHMIC ACTIONS OF A LONG ACTING VERAPAMIL ANALOGUE, ANIPAMIL, IN PIGS C. Ries, C.J. Harvie, M.J.A. Walker & MLK. Pugsley VASCULAR REACTIVITY: MODULATION BY HYPOXIA J.C. Wanstall Chemotherapy ADAPTOGENIC SCREENING IN RATS T.H.T. Hui, H.I. Runion & M.G. Chaubal HISTOLOGICAL CHANGES IN THE TIBIA OF THE MOUSE FETUS EXPOSED TO DIAZEPAM A. Marquez-Orozco, M.C. Marquez-Orozco & EFFECTS OF DIAZEPAM ON THE ULTRASTRUCTURE OF FETAL MICE HEPATOCYTES M.C. Marquez-Orozco, A. Marquez-Orozco & M.V. Gazca-Ramirez TESTICULAR HISTOLOGICAL CHANGES IN MICE AFTER PRENATAL ADMINISTRATION OF DIAZEPAM M.V. Mata-Santibanez, M.C. Marquez-Orozco & A. Marquez-Orozco DIAZEPAM INDUCED HISTOLOGICAL CHANGES IN THE TESTES OF ADULT MICE M. Ramos-Avila, M.C. Marquez-Orozco & A. Marquez-Orozco THE EFFECTS OF HEXADECYLPHOSPHOCHOLINE (HPC), A MIXTURE OF ALKYLPHOSPHOCHOLINES (APC) AND DIFFERENT DIETARY OILS, ON THE GROWTH OF A HUMAN MAMMARY TUMOR D.T. Colombo, L.K. Tran & R.C. Reitz Clinical pharmacology COMPARATIVE STUDY OF KETOROLAC AND DIPYRONE IN THE TREATMENT OF POSTOPERATIVE PAIN L.G. Ibarra-Ibarra, M.A. Cubillo, A. Silva-Adaya & C.A. Gonzdlez-Garcia PHARMACOKINETIC AND PHARMACODYNAMIC COMPARISONS OF ORAL AND SUBLINGUAL NIFEDIPINE IN HYPERTENSIVE MEXICAN PATIENTS J.A. Palma-Aguirre, A. Roa-Mendieta, L.M. Hernandez-Jiménez, M.E. Girard-Cuesy, F. Leén-Urrea, A. Alfaro-Mejfa, A. Frati & O. Barreiro-Perera Endocrinology COMPARISON OF THE TIME COURSE OF ANTICOAGULANT AND ESTROGENIC EFFECTS OF PROLAME, BUTOLAME, PENTOLAME AND HEXOLAME, A HOMOLOGOUS SERIES OF 178-AMINO ESTROGENS C. Rubio-Péo, C. Lemini, G. Silva, J. Garcfa-Mondragén, E. Zavala, D. Castro, N. Mendoza-Patifio & J.J. Mandoki THE EFFECTS OF STRESS ON PLASMA LIPIDS AND ANTIOXIDANT STATUS IN RATS WITH DIET INDUCED HYPERLIPIDEMIA P.M. Toleikis & D.V. Godin General ACYL GLUCURONIDE CONJUGATES: REACTIVE METABOLITES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS R.G. Dickinson DOES COCAINE AT ITS LDc, EXHIBIT A CYTOPROTECTIVE EFFECT ON THE GASTRIC MUCOSA? L. Angus, A.R. Abadir, H. Levendoglu & J. Gintautas SERUM COCAINE IN THE RAT: BEHAVIOR AND PHARMACOKINETIC STUDY J. Gintautas, L. Angus, H. Levendoglu & ARE ENANTIOSELECTIVE ASSAY METHODS NECESSARY FOR COMPARATIVE BIOAVAILABILITY STUDIES ON RACEMIC DRUGS? W.D. Hooper REDUCED SENSITIVITY TO AZT OF SIV ISOLATES FROM MORPHINE TREATED RHESUS MONKEYS K.F. Killam, Jr., A.J. Chuang & R.Y. Chuang THE LIVER DOES NOT EXPORT ADENOSINE UNDER PHYSIOLOGICAL CONDITIONS Y. Zhang & W.W. Lautt EFFICACY OF BUTOCONAZOLE NITRATE IN THE TREATMENT OF VULVO-VAGINAL CANDIDIASIS COMPARED WITH CLOTRIMAZOL AND ISOCONASOL A. Lépez-Fiesco, A. Ayala-Ruiz, L.M. Romo, M.D. Delgado & G. Zamora DEVELOPMENT OF A FACULTY RESEARCH INTERESTS DATABASE T. McCalden & G. Chapman 4-AMINOPYRIDINE ANTAGONIZES LETHALITY INDUCED BY SAXITOXIN IN MICE D. Santamaria, C. Rios, J. Kravzov & M. Altagracia REGULATION OF HUMAN PERIPHERAL TYPE BENZODIAZEPINE RECEPTORS (PBR): EFFECT OF 3-AMINO-1,2,4-TRIAZOLE (AT) J.D. Militante & P.J. Syapin QUANTITATION OF NITRIC OXIDE BY A COMPUTERIZED CHEMILUMINESCENCE DETECTOR MEASUREMENT OF PHOTOLYTIC DEGRADATION OF STREPTOZOTOCIN AND SODIUM NITROPRUSSIDE TO RELEASE NITRIC OXIDE S.K. O'Neill, S. Dutta & C.R. Triggle STOBADINE PROTECTS ION PUMP ATPases FROM FREE RADICAL INHIBITION K.A. Clinch, F.F. Vincenzi, T.T. Rohn & T.R. Hinds EFFECT OF PROBENECID AND ITS CONGENERS ON BRAIN ORGANIC ACID TRANSPORT IN RATS M. Altagracia, C. Rios, J. Kravzov & F. Lépez-Naranjo CEREBELLAR HISTOLOGICAL CHANGES PRODUCED BY DIAZEPAM R. Andrada-Martinez, M.C. Marquez-Orozco & A. Marquez-Orozco EFFECT OF RESERPINE ON SLEEP PATTERNS IN A CHELONIAN REPTILE (GOPHEROUS BERLANDIERI) F. Ayala-Guerrero, S. Huitron-Resendiz & G. Mexicano EFFECT OF A THIONE ON SLEEP DISTURBANCES ASSOCIATED WITH CHRONIC PAIN F. Ayala-Guerrero, L.U. Guevara, J. Taboada & R. Martinez OPIOID PEPTIDE ADMINISTRATION AND MEMORY FORMATION: EFFECTS OF ADMINISTRATION VEHICLE P.J. Colombo, K.R. Thompson, J.L. Martinez Jr., E.L. Bennett & M.R. Rosenzweig COMPARISON OF THE ANALGESIC EFFECTS OF KETOROLAC, MORPHINE AND ASPIRIN IN THE RAT V. Granados-Soto, F.J. Flores-Murrieta, G. Castafieda-Hernandez, E. Hong & F.J. Lépez-Mujioz -XXiv- EVIDENCE FOR THE UP-REGULATION OF KAPPA OPIATE MECHANISMS IN MICE SELECTIVELY BRED FOR HIGH ANALGESIA B. Kest, J.S. Mogil, W.F. Sternberg, J.C. Liebeskind & B. Sadowski PROTECTIVE EFFECT OF PROBENECID ON CIRCLING BEHAVIOR OF RATS WITH UNILATERAL QUINOLLINIC ACID INDUCED STRIATAL LESIONS J. Kravzov, A. Santamaria, C. Rios, A. Flores & M. Altagracia EEG EVALUATION OF THE ANTICONVULSIVE EFFECT OF DAPSONE IN THE KAINIC ACID MODEL OF EPILEPSY C. Rios, M. Altagracia, J. Kravzov, A. Monroy-Noyola, R. Alvarado-Calvillo, J. Manjarrez-Marmolejo & L. Osorio-Rico ANALGESIC EFFECTS OF MULTIPLE COMBINATIONS OF MORPHINE AND ASPIRIN IN THE RAT FJ. Lépez-Mufioz & L.A. Salazar INNATELY HEARING IMPAIRED SPRAGUE-DAWLEY RATS EXHIBIT AUDIOGENIC SEIZURE SUSCEPTIBILITY FOLLOWING MONOAMINE DEPLETION C.E. Reigel & C.L. Faingold TOXICITY OF &-AMYLOID,<4 , PEPTIDE IN PC12 CELLS EM. Clark & R. Vulliet COCAINE CAUSES A TIME DEPENDENT AND DOSE DEPENDENT INCREASE IN D, RECEPTORS AND DOPAMINE TRANSPORTERS J.R. Wamsley & M.E. Alburges COMPARISON OF THE EFFECTS OF PROPOFOL, DIAZEPAM AND PENTOBARBITAL ON HIPPOCAMPAL POTENTIALS EVOKED BY PREPYRIFORM STIMULATION IN THE FREELY BEHAVING RAT Z.A. Hasan, H.L. Drummer, L. Zimmer, T. Tubbs & D.E. Woolley AMANTADINE ENHANCES DOPAMINE AND SEROTONIN TURNOVER IN THE MPTP MODEL OF PARKINSON'S DISEASE M. Altagracia, P. Rojas, J. Kravzov & C. Rios Neuroscience THE NMDA RECEPTOR ANTAGONIST MK-801 BLOCKS NON-OPIOID STRESS INDUCED ANALGESIA AND DECREASES TUMOR METASTASIS IN THE RAT S. Ben-Eliyahu, G.G. Page, P. Marek, B. Kest, A.N. Taylor & J.C. Liebeskind CHARACTERIZATION AND MAPPING OF A DELTA OPIOID RECEPTOR CLONE FROM NG108-15 CELLS DE. Keith Jr., B. Anton & C.J. Evans THE NMDA RECEPTOR ANTAGONIST MK-801 PROTECTS AGAINST THE DEVELOPMENT OF MORPHINE TOLERANCE AFTER INTRATHECAL ADMINISTRATION B. Kest, J.S. Mogil, B-E. Shamgar, B. Kao, J.C. Liebeskind EFFECTS OF CENTROMEDIAL AMYGDALOID (CMA) LESIONS ON THE DIAZEPAM ANXIOLYSIS I. Zarco de Coronado, M.A. Barrios-Figueroa, M. de J. Vivar-Estudillo & M. de L. Palacios-Perez Smooth muscle RELAXATION OF RINGS OF CEREBRAL ARTERY PRODUCED BY A COMPOUND DERIVED FROM A PAPUA NEW GUINEA SPONGE M. Doi, T.M. Allen, R. Andersen, D.A. Cook, C.F.B. Holmes & G. Kao 82-AGONIST BRONCHODILATORS - ADVANCES VERSUS CONTROVERSIES S.R. O'Donnell General EFFECT OF PIROXICAM AND TENOXICAM ON ETHANOL METABOLISM IN TACONIC MICE L. VAazquez-Osornio, S. Miranda-Sdnchez, E. Perez-Tapia, C. Rodriguez-Rodriguez, A. Rivera-Aguilar, F. Allende-Herrera, R. Ruiz-Soto, M. Lorenzana-JIménez & M.D. Ramirez-Gonzalez ABSTRACTS (Alphabetically by first author) INDEX OF AUTHORS A fee a sl