Preventive Strikes This page intentionally left blank Preventive Strikes Women, Precancer, and Prophylactic Surgery (cid:1) ILANA LÖWY (cid:1) The Johns Hopkins University Press Baltimore ©2010The Johns Hopkins University Press All rights reserved.Published 2010 Printed in the United States ofAmerica on acid-free paper 2 4 6 8 9 7 5 3 1 The Johns Hopkins University Press 2715North Charles Street Baltimore,Maryland 21218-4363 www.press.jhu.edu Library ofCongress Cataloging-in-Publication Data Löwy,Ilana Preventive strikes :women,precancer,and prophylactic surgery / Ilana Löwy. p. cm. Includes bibliographical references and index. ISBN-13:978-0-8018-9364-3(hardcover :alk.paper) ISBN-10:0-8018-9364-X (hardcover :alk.paper) 1. Cancer in women—Surgery—Social aspects. 2. Precancerous conditions— Surgery—Social aspects. 3. Breast—Cancer—Surgery—Social aspects. 4. Ovaries—Cancer—Surgery—Social aspects. 5. Social medicine. I. Title. [DNLM:1. Neoplasms—prevention & control—France. 2. Neoplasms— prevention & control—Great Britain. 3. Neoplasms—prevention & control— United States. 4. Precancerous Conditions—surgery—France. 5. Precancerous Conditions—surgery—Great Britain. 6. Precancerous Conditions—surgery— United States. 7. Genetic Predisposition to Disease—France. 8. Genetic Predisposition to Disease—Great Britain. 9. Genetic Predisposition to Disease— United States. 10. History,20th Century—France. 11. History,20th Century— Great Britain. 12. History,20th Century—United States. 13. Women’s Health— France. 14. Women’s Health—Great Britain. 15. Women’s Health—United States. QZ204L917p2009] RC281.W65L692009 616.99(cid:1)4071—dc22 2008056007 A catalog record for this book is available from the British Library. Special discounts are available for bulk purchases ofthis book.For more information, please contact Special Sales at 410-516-6936or [email protected]. The Johns Hopkins University Press uses environmentally friendly book materials, including recycled text paper that is composed ofat least 30percent post-consumer waste,whenever possible.All ofour book papers are acid-free,and our jackets and covers are printed on paper with recycled content. To Barbara Rosenkrantz This page intentionally left blank contents (cid:1) Acknowledgments ix Introduction:Embodied Risk 1 chapter one Biopsy 19 chapter two Classifications 40 chapter three Borderline Lesions 55 chapter four In Situ Cancers 84 chapter five The Origins ofScreening 118 chapter six The Generalization ofScreening 143 chapter seven Heredity 166 chapter eight The New Surgical Radicalism 198 Conclusion:Uncertainty 225 Notes 239 Index 323 This page intentionally left blank acknowledgments My first debt is to the institutions that have made this research possible.INSERM— the French Institute ofHealth and Medical Research—has given continual sup- port to my atypical investigations,while my research center,CERMES,has pro- vided excellent intellectual and material conditions for my work,a rare privilege in a time of reduced support for “useless” studies, those devoid of economic value.Additional support for this study has come from grants from the Fonda- tion de France and the French National Cancer Institute (INCa).I was extremely lucky to able to benefit from the resources oftwo extraordinary institutions:The Radcliffe Institute,where I started the research on this book,and the Max Planck Institute for the History ofScience (MPIWG),where I wrote large parts ofit.My gratitude goes to Drew Faust and Judith Vichniac at the Radcliffe Institute and to Loraine Daston,Jürgen Renn,and Hans Jörg Rheinberger at the MPIWG,for cre- ating a scholars’paradise. My second—and crucial—debt is to archivists.The invisible work oflibrari- ans and archivists makes historical studies possible.While working on this book I met highly skilled,dedicated,and enthusiastic archivists.I’m very grateful to Nathalie Huchette and Laurence Leclerc at the Curie Institute,Paris; Jonathan Evans and his colleagues at the London Hospital Archives;Katie Ormerod and her colleagues at the Archives of St Bartholomew’s Hospital, London; Hilary Ritchie at Addenbrooke’s Hospital,Cambridge (UK);Jim Gehrlich at the Archives Service ofNew York Hospital;Stephen Novak and his colleagues at the Archives and Special Collections ofthe Health Sciences Library,Columbia University;and Jack Eckert and the staffofthe Rare Books and Manuscript Department,Count- way Library,Harvard University,for their essential help. Research is a collective endeavor,and exchanges with colleagues are one of the great pleasures ofthat occupation.This study started as an investigation of