Practical Approach to Paediatric Gastroenterology, Hepatology and Nutrition Practical Approach to Paediatric Gastroenterology, Hepatology and Nutrition Deirdre Kelly, MD, FRCP, FRCPI, FRCPH The Liver Unit Birmingham Children’s Hospital; Professor of Paediatric Hepatology University of Birmingham Birmingham, UK Ronald Bremner, DM, FRCPCH Consultant Paediatric Gastroenterologist Department of Gastroenterology and Nutrition Birmingham Children’s Hospital Birmingham, UK Jane Hartley, MBChB, MRCPCH, MMedSc, PhD Consultant in Paediatric Hepatology and Small Bowel Transplantation The Liver Unit Birmingham Children’s Hospital Birmingham, UK Diana Flynn, MBBCh, MRCPCH, BSc, PhD Consultant Paediatric Gastroenterologist Department of Gastroenterology Royal Hospital for Sick Children Glasgow, UK This edition first published 2014 © 2014 by John Wiley & Sons, Ltd. 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ISBN 978-0-470-67314-0 (pbk. : alk. paper) – ISBN 978-1-118-77866-1 (epdf) – ISBN 978-1-118-77882-1 (epub) – ISBN 978-1-118-77883-8 (emobi) I. Hartley, Jane, author. II. Flynn, Diana, author. III. Kelly, Deirdre A., editor. IV. Title. [DNLM: 1. Gastrointestinal Diseases–Handbooks. 2. Child Nutrition Disorders– Handbooks. 3. Child. 4. Infant Nutrition Disorders–Handbooks. 5. Infant. 6. Liver Diseases–Handbooks. WS 39] RJ446 618.92'33–dc23 2013024997 A catalogue record for this book is available from the British Library. Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books. Cover image: iStock File #7646055 © Fertnig Set in 9/12 pt Palatino by Toppan Best-set Premedia Limited 1 2014 Contents Preface, vii Acknowledgements, viii Part I Gastroenterology, 1 1 The infant with abdominal pain, 3 2 The child with abdominal pain, 6 3 The infant with vomiting, 15 4 The child with vomiting, 21 5 Difficulty swallowing, 24 6 Abdominal distension, 29 7 The infant with acute diarrhoea, 32 8 The child with acute diarrhoea, 35 9 The infant with chronic diarrhoea, 40 10 The child with chronic diarrhoea, 47 11 Gastrointestinal bleeding, 61 12 Food-associated symptoms, 67 13 Abdominal mass, 76 14 The infant with constipation, 79 15 The child with constipation, 83 16 Perianal pain, 90 Part II Hepatology, 93 17 The infant with jaundice, 95 18 The acutely unwell infant, 108 19 The infant with splenomegaly, 118 20 The infant with a hepatic cause for abdominal distension, 121 21 The older child with jaundice, 128 22 The older child who is acutely unwell, 134 23 The older child with hepatic causes of abdominal distension, 138 24 Chronic liver disease: itching, 141 25 Chronic liver disease: ascites, 145 26 Chronic liver disease: haematemesis or meleana, 148 v vi | Contents 27 Children with incidental abnormal liver biochemistry, 150 28 The child with cystic fibrosis, 152 29 The child with liver disease following chemotherapy, 155 30 The management of a child with acute liver failure, 158 31 Indications for liver transplant, 164 32 Complications following liver transplant, 166 Part III Nutrition, 171 33 Nutritional monitoring, 173 34 Nutrition in the normal infant: breast-feeding, 176 35 Nutrition in the normal infant: infant formulae, 180 36 Nutrition in premature infants, 183 37 Problems with weaning, 186 38 The infant or child with poor feeding, 188 39 Food aversion, 192 40 Ingestion of non-food items (pica), 194 41 Nutrition in neurodisability, 198 42 Malnutrition, 201 43 Obesity, 209 44 Intestinal failure, 213 45 Parenteral nutrition: initiating and monitoring, 225 46 Parenteral nutrition: complications, 230 47 Parenteral nutrition: weaning, 237 48 Home parenteral nutrition, 239 49 Enteral tube feeding, 241 50 Nutrition in cystic fibrosis, 247 Index, 249 Preface Paediatrics is a rapidly evolving field of medicine, particularly in the sub-specialties. This makes it difficult for trainees, junior doctors and allied health professionals to keep up with new developments. This book aims to provide problem-orientated clinical scenarios in paediatric gastroenterology, hepatology and nutrition, and is designed to make initial assessment, management and referral of children easy to follow. The book is up to date with current practice, user friendly, with links to the latest guidance, protocols and information, and should be a popular book no trainee doctor should be without. We hope you enjoy using it and that it will help you improve how you manage children with these specialist conditions. vii
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