Chapter 03 *Lecture and Animation Outline with Anatomy & Physiology Revealed Images To run the animations you must be in Slideshow View. Use the buttons on the animation to play, pause, and turn audio/text on or off. Please Note: Once you have used any of the animation functions (such as Play or Pause), you must first click on the slide’s background before you can advance to the next slide. *See separate FlexArt PowerPoint slides for all figures and tables pre-inserted into PowerPoint without notes and animations. 1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Type Institution Name Here Type Course Number Here: Type Course Name Here Chapter 3 Type Professor Name Here Type Academic Rank Here Type Department Name Here 2 3.1: Introduction • The basic organizational structure of the human body is the cell. • There are about 75 trillion cells in the human body. • Cell size is measured in micrometers. • Differentiation is when cells specialize. • As a result of differentiation, cells vary in size and shape due to their unique function. 3 3.2: A Composite Cell Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. • Also called a ‘typical’ Phospholipid bilayer Flagellum cell Nucleus Nuclear envelope Chromatin • Major parts include: Nucleolus Ribosomes Microtubules Basal body Cell membrane • Nucleus Centrioles Rough Endoplasmic reticulum Mitochondrion Smooth • Cytoplasm Endoplasmic reticulum • Cell membrane Microvilli Secretory vesicles Cilia Golgi apparatus Microtubule Microtubules 4 L ysosomes The Generalized Cell Cell Membrane (aka Plasma Membrane) • Outer limit of the cell • Controls what moves in and out of the cell • Selectively permeable • Phospholipid bilayer • Water-soluble “heads” form surfaces (hydrophilic) • Water-insoluble “tails” form interior (hydrophobic) • Permeable to lipid-soluble substances • Cholesterol stabilizes the membrane • Proteins: • Receptors • Pores, channels and carriers • Enzymes • CAMS • Self-markers 6 Cell Membrane Cell Membrane Inner leaflet Extracellular matrix Outer leaflet Plasma membranes Cytoplasm Cell Membrane Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Extracellular side of membrane Glycolipid Carbohydrate Fibrous protein Glycoprotein “Heads” of phospholipid Double layer of “Tails” of phospholipid Phospholipid molecules Cell membrane Cell membrane Cholesterol Globular Hydrophobic (a) (b) a: © Biophoto Associates/Photo Researchers, Inc. molecules protein fatty acid “tail” Hydrophilic Cytoplasmic side Phosphate of membrane “head” 9 Membrane Lipids Membrane Proteins Membrane Carbohydrates
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