Posterior Uveitis: Advances in Imaging and Treatment PDF
Preview Posterior Uveitis: Advances in Imaging and Treatment
Essentials in Ophthalmology Series Editor: Arun D. Singh Narsing A. Rao Julie Schallhorn Damien C. Rodger Editors Posterior Uveitis Advances in Imaging and Treatment Essentials in Ophthalmology Series Editor Arun D. Singh Cleveland Clinic Foundation Cole Eye Institute Cleveland, OH, USA More information about this series at http://www.springer.com/series/5332 Narsing A. Rao • Julie Schallhorn Damien C. Rodger Editors Posterior Uveitis Advances in Imaging and Treatment Editors Narsing A. Rao Julie Schallhorn Ophthalmology Department of Ophthalmology USC Roski Eye Institute Ophthalmology and Francis I. Proctor Foundation Los Angeles, CA University of California, San Francisco USA San Francisco, CA USA Damien C. Rodger Department of Ophthalmology Kaiser Permanente Los Angeles Medical Center Los Angeles, CA USA ISSN 1612-3212 ISSN 2196-890X (electronic) Essentials in Ophthalmology ISBN 978-3-030-03139-8 ISBN 978-3-030-03140-4 (eBook) https://doi.org/10.1007/978-3-030-03140-4 Library of Congress Control Number: 2019930846 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland Preface We have the great fortune of practicing medicine at a time of rapid discovery and advancement. Every coming year brings new diagnostics, new therapeutics, and an evolving insight into the genesis of uveitis and related intraocular inflammatory diseases. We have collected here an in-depth examination of the diseases, imaging techniques, and treatments that are being reshaped by the advances in our field. The first section will tour a multitude of infectious and noninfectious uveitidies and explore how advances are aiding our diagnosis and treatment. The second sec- tion will delve into established and emerging therapeutics, including advances in drug delivery. We are aided in this journey by a panoply of experts from around the world, bringing a truly international view to this subject. We hope that readers find Advances in Intraocular Inflammation Imaging and Treatment useful as they navigate and incorporate the changes in the field in diag- nosis and management of intraocular inflammation and prepare for what is to come. Los Angeles, CA, USA Narsing A. Rao San Francisco, CA, USA Julie Schallhorn Los Angeles, CA, USA Damien C. Rodger v Contents Part I Introduction Posterior Uveitis: Role of Imaging Modalities . . . . . . . . . . . . . . . . . . . . . . . . 3 Phuc V. Le Part II N on-Infectious Posterior or Pan Uveitis Ocular Sarcoidosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Padmamalini Mahendradas, Ankush Kawali, and Sujay Chauhan Vogt-Koyanagi-Harada Disease and Sympathetic Ophthalmia . . . . . . . . . . 39 Jeffrey J. Tan and Narsing A. Rao Multifocal Choroiditis/Serpiginous Choroiditis and Related Entities . . . . . 57 Hossein Nazari Khanamiri and Narsing A. Rao Part III Infectious Posterior or Panuveitis Ocular Toxoplasmosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 Daniel Vitor Vasconcelos-Santos Ocular Syphilis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99 Francesco Pichi and Thomas A. Albini Ocular Tuberculosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 Soumyava Basu Viral Retinitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 Dana Yousef Darwish, Mei Zhou, and Ann-Marie Lobo Intraocular Lymphoma: A Posterior Uveitis Masquerade Syndrome . . . . . 141 Brian K. Do, Jesse L. Berry, and Damien C. Rodger vii viii Contents Part IV N on-Infectious Uveitis: Treatment Options Noninfectious Uveitis: Systemic and Local Corticosteroids . . . . . . . . . . . . . 159 Ashleigh Laurin Levison Noninfectious Uveitis: Immunomodulatory Agents and Biologicals . . . . . . 175 John A. Gonzales and Nisha Acharya Noninfectious Uveitis: Emerging Therapies . . . . . . . . . . . . . . . . . . . . . . . . . . 209 Julie Schallhorn Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 Contributors Nisha Acharya, MD, MS F.I. Proctor Foundation, University of California, San Francisco, San Francisco, CA, USA Thomas A. Albini, MD Bascom Palmer Eye Institute, University of Miami Miller School, Department of Ophthalmology, Miami, FL, USA Soumyava Basu, MS Retina and Uveitis Service, L V Prasad Eye Institute, Bhubaneswar, India Jesse L. Berry, MD USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Department of Ophthalmology, Los Angeles, CA, USA Children’s Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA Sujay Chauhan, DO Narayana Nethralaya, Department of Uveitis and Ocular Immunology, Bangalore, India Dana Yousef Darwish, BS Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Department of Ophthalmology and Visual Sciences, Chicago, IL, USA Brian K. Do, MD USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Department of Ophthalmology, Los Angeles, CA, USA John A. Gonzales, MD F.I. Proctor Foundation, University of California, San Francisco, San Francisco, CA, USA Ankush Kawali, DNB Narayana Nethralaya, Department of Uveitis and Ocular Immunology, Bangalore, India Phuc V. Le, MD, PhD UCLA Department of Ophthalmology, Doheny Eye Institute, Pasadena, CA, USA Ashleigh Laurin Levison, MD Colorado Retina Associates, Denver, CO, USA Ann-Marie Lobo, MD Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Department of Ophthalmology and Visual Sciences, Chicago, IL, USA ix x Contributors Padmamalini Mahendradas, DO, DNB Narayana Nethralaya, Department of Uveitis and Ocular Immunology, Bangalore, India Hossein Nazari Khanamiri, MD University of Texas medical Branch, Department of Ophthalmology and Visual Sciences, Galveston, TX, USA Francesco Pichi, MD Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA Narsing A. Rao, MD Ophthalmology, USC Roski Eye Institute Ophthalmology, Los Angeles, CA, USA Damien C. Rodger, MD, PhD Department of Ophthalmology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA Julie Schallhorn, MD, MS Department of Ophthalmology and Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, CA, USA Jeffrey J. Tan, MD USC Roski Eye Institute, Department of Ophthalmology, Los Angeles, CA, USA Daniel Vitor Vasconcelos-Santos, MD, PhD Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, Brazil Mei Zhou, MD Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Department of Ophthalmology and Visual Sciences, Chicago, IL, USA Part I Introduction
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