Pocket Prescriber Psychiatry PDF
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30 Journal of Psychopharmacology00(0) Rapid Tranquilisation Algorithm ‘This book condenses huge amounts of up-to-date prescribing knowledge into a concise and P o AduAAlddt uuAllttL SAA L(LASS d((AAvaddnvvacaenndcce eLddi f LLeii ffSeeu SSpuupppopproot)rr ttC)) a CCraadrriddaiciaa Acc rAArrerrrseetss tAt AAlgllgogoroirrtiihtthhmmm easy-to-use format. Doctors, pharmacists and nurses caring for patients with neuropsychiatric c Pocket European Resuscitation Council Guidelines 2017 disorders should read it. They will enjoy it and their patients will benefit in turn.’ k e Unresponsive? Professor Sir Robin Murray FRS, Professor of Psychiatric Research, Institute of Psychiatry, t Not breathing or only occasional gasps Psychology & Neuroscience, King’s College London, UK P Prescriber r Call e Resuscitation s Team ‘What a great idea! I only wish we had something like this back in my day.’ c Professor Sir Simon Wessely, Regius Professor of Psychiatry, Institute of Psychiatry, rib Attach dCePfiRb r3il0la:2tor/monitor Psychology & Neuroscience, King’s College London; President of Royal Society of Medicine; Past e Psychiatry (cid:127) Minimise interruptions President of Royal College of Psychiatrists r P s Pocket Prescriber Psychiatry is a concise, up-to-date prescribing guide containing all the y Assess Rhythm c ‘must-have’ information that psychiatrists and mental health professionals need to know. h Shockable Non-shockable KEY FEATURES ia (VF/Pulseless VT) (PEA/Asystole) t • A–Z list of most commonly prescribed drugs with key prescribing information r Return of y spontaneous • Covers safety issues, warnings, drug errors and adverse effects circulation • Practical guidance on drug selection, plus protocols and guidelines R IMMEDIATE POST CARDIAC • Advice for complicated prescriptions and drug interactions o ARREST TREATMENT • Concise management summaries for psychiatric emergencies and rapid tranquilization ger 1 Shock (cid:127)(cid:127) UCosen tAroBlCleDdE oaxpypgreonaacthion and An algorithm for the management of acute disturbance. ••••Th isAICfmEP nabdnslceicoyvdnodtcoioisrcihkcrpc e asofoop replflrorleodhayomgr atvub ea sirbsydsmlp eae teekfahssscuec iesifycloa eo Brlplpnceo rophutmgiiitoasynaiipesrntlmsdhusd laefiAanrrcstosfiosomo loornom fcgsm ia,yaa e, stt wnaiiuootescnnaa hw llff thaooehrerls l a o ataflhlt sl he ealndde rclya wpCeaadRnicCdtwii toPdynrr welsue sgigsn/i. a staillct carleoatrihsno ognacler em po afis vdruaisgieleiatrabssll efs oars.m eacBtsoookm s • Leung • Nicholson D(cid:127)(cid:127)(cid:127)(cid:127)(cid:127)(cid:127) UEPGCCVnlooRaiavsnnsIMneNucst I uriiGamioCdnenlcxa Peu miCthymrRrioP goi ea guaiR3endzchds0nesci -va ce: qb2iahtsnuee nseft flaocs(eyoitler rni rr tdrce2teyuo r s apaimmCunivtrPmtiipwenoRernern:ae orryssuaus apitsoen,t ni,din nsd g ctwera CapphPotne(cid:127)(cid:127)(cid:127) hRs no s,1TTvh e gre2reayoeern-mpdauclateovoppstiaatl) iheaplhdnyrtre caiEeoertCcmdnuiGp riaaeiti racwotinanytgr iocnla /puthlsaeecreapeutR(cid:127)(cid:127)(cid:127)(cid:127)(cid:127)(cid:127)i EcHHHHTTVhayyyyEmrppppoRoooopmSxv-to/IhioMbBhanelIoLyaamirCEnpsemdiP miemseCmRi ra –Aeki– ia 3dzU acc0eoilSaaa: r2iErteonde Smfntiloeayair rcarr ry2e/u m sopmuretmi itnpoaeunblsomliocnary Reprinted from Patel & Sethi et al., Joint BAP NAPICU evidence-based consensus Figure 1. manedn tisa la hne easltshe nptrioafle gssuiiodnea flosr pprseyscchriibaitnrigs tdsr,u gs Jonathan P Rogers (cid:127)(cid:127) GCoivrere acdt rreenvaelrisnibel e(e cpainuesepshrine) every 3–5 min (cid:127)(cid:127) TToenxisniosn pneumothorax guidelines for the clinical management of acute disturbance: De-escalation and rapid tranquillisation, Journal of Psychopharmacology, 32(6), 601–640, 2018, SAGE Publishing, mental health nurses, primary care physicians, https://doi.org/10.1177/0269881118776738 Cheryl CY Leung psychologists, psychotherapists and counsellors, • When deciding between options consider patient preference, health problems / pregnancy, intoxication, previous response, SEs, interactions & total dose prescribed.NICE and anyone caring for people with mental Timothy RJ Nicholson • For IM RT, use lorazepam rather than an antipsychotic if no info about previous response, no ECG, pre-existing cardiac disease or antipsychotic-naïve.NICE health issues. Pocket Prescriber Psychiatry Pocket Prescriber Psychiatry Edited by Jonathan P Rogers MA MB BChir MRCP MRCPsych NIHR Academic Clinical Fellow, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, and South London and Maudsley NHS Foundation Trust, London, UK Cheryl CY Leung BSc (Hons) BMedSc BMBS NIHR Academic Clinical Fellow, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, and South London and Maudsley NHS Foundation Trust, London, UK Timothy RJ Nicholson MBBS BSc MSc PhD MRCP MRCPsych Clinical Lecturer & NIHR Clinician Scientist, Institute of Psychiatry Psychology & Neuroscience, King’s College London, and Honorary Consultant Neuropsychiatrist, South London & Maudsley NHS Foundation Trust CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2020 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Printed on acid-free paper International Standard Book Number-13: 978-1-4441-7666-7 (Paperback) This book contains information obtained from authentic and highly regarded sources. While all reasonable efforts have been made to publish reliable data and information, neither the author[s] nor the publisher can accept any legal responsibility or liability for any errors or omissions that may be made. The publishers wish to make clear that any views or opinions expressed in this book by individual editors, authors or contributors are personal to them and do not necessarily reflect the views/opinions of the publishers. The information or guidance contained in this book is intended for use by medical, scientific or health-care professionals and is provided strictly as a supplement to the medical or other professional’s own judgement, their knowledge of the patient’s medical history, relevant manu- facturer’s instructions and the appropriate best practice guidelines. Because of the rapid advances in medical sci- ence, any information or advice on dosages, procedures or diagnoses should be independently verified. The reader is strongly urged to consult the relevant national drug formulary and the drug companies’ and device or material manufacturers’ printed instructions, and their websites, before administering or utilizing any of the drugs, devices or materials mentioned in this book. This book does not indicate whether a particular treatment is appropriate or suitable for a particular individual. Ultimately it is the sole responsibility of the medical professional to make his or her own professional judgements, so as to advise and treat patients appropriately. The authors and publishers have also attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowl- edged please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, includ- ing photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http:// www.copyright.com/) or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. Library of Congress Cataloging-in-Publication Data Names: Rogers, Jonathan P., editor. | Leung, Cheryl C. Y., editor. | Nicholson, Timothy R. J., editor. Title: Pocket prescriber psychiatry / edited by Jonathan P. Rogers, Cheryl C.Y. Leung, Timothy R.J. Nicholson. Description: Boca Raton : CRC Press, [2019] | Includes bibliographical references and index. Identifiers: LCCN 2019015207 (print) | LCCN 2019016846 (ebook) | ISBN 9780429317330 (eBook) | ISBN 9781444176667 (pbk. : alk. paper) Subjects: | MESH: Mental Disorders--drug therapy | Drug Prescriptions | Handbook Classification: LCC RC454 (ebook) | LCC RC454 (print) | NLM WM 34 | DDC 616.89--dc23 LC record available at https://lccn.loc.gov/2019015207 Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com CONTENTS Contributors vii Foreword ix Acknowledgements x How to Use this Book xi List of Abbreviations xiv How to Prescribe Safely xxv Common/useful drugs 1 Disorders 182 Psychosis 183 Bipolar affective disorder 206 Depression 226 Anxiety disorders 243 Dementia 255 Attention deficit hyperactivity disorder (ADHD) 268 Sleep disorders and agitation 280 Substance misuse 292 Non-pharmacological treatments 312 Psychoeducation 313 Crisis planning 313 Lifestyle interventions 314 Social interventions 316 Psychological therapies 319 Neurostimulation 323 Psychosurgery 325 Basic psychopharmacology 326 Pharmacokinetics 327 Pharmacodynamics 331 Neurotransmitter systems 334 Drug interactions 341 Miscellaneous 350 Prescribing in the perinatal period 351 vi Contents Prescribing in autism 354 Prescribing in personality disorders 354 Controlled drugs (CDs) 355 Off-license prescribing 357 Psychiatric side effects of medications 358 Medication adherence 358 Risk assessment 359 Psychiatric classification 361 Mental Health Act (MHA) in England and Wales 364 Mental Capacity Act (MCA) in England and Wales 369 Emergencies 372 Rapid tranquilisation (RT) 373 Drug toxicity syndromes 380 Alcohol and drug withdrawal syndromes 390 Catatonia 393 Delirium 395 Seizures (epileptic and dissociative) 397 Acute dystonia 399 Clozapine-induced agranulocytosis 399 HIV post-exposure prophylaxis (PEP) 400 Hanging 401 Self-laceration 402 Acute coronary syndromes (ACS) 404 Acute asthma 408 Chronic obstructive pulmonary disease exacerbation 409 Pulmonary embolism 410 Sepsis (severe or septic shock) 410 Diabetic ketoacidosis (DKA) 412 ↓Glucose 414 Reference information 416 Guidelines 417 Useful contacts 422 Reference values 424 Index 429 CONTRIBUTORS Prof David S. Baldwin MA DM FRCPsych Ms Jules Haste BSc DipClinPharm Professor of Psychiatry MRPharmS, MCMHP Faculty of Medicine Principal Pharmacist University of Southampton Sussex Partnership NHS Foundation Trust Southampton, UK Sussex, UK Prof David Coghill BSc (Med Sci) MB Dr Frank Holloway FRCPsych ChB, MD South London and Maudsley Hospital NHS Financial Markets Foundation Chair of Foundation Trust Developmental Mental Health London, UK Departments of Paediatrics and Psychiatry Dr Jonathan Huntley PhD MBBS BA Faculty of Medicine Clinical Lecturer and Wellcome Trust Dentistry and Health Sciences Clinical Fellow University of Melbourne Division of Psychiatry, University College London Melbourne, Australia and Dr Fiona Cresswell MBChB BSc MRCP Honorary Consultant Old Age Psychiatrist DTM&H DipGUM PGCert Epi Camden and Islington NHS Foundation Trust Clinical PhD Fellow London, UK Faculty of Infectious and Tropical Diseases Dr Hind Khalifeh PhD BMBCh MRCPsych London School of Hygiene and Tropical NIHR Research Fellow and Hon Consultant Medicine Psychiatrist London, UK King’s College London and Dr Thomas Dewhurst MBBCh MRCPsych South London and Maudsley NHS Specialty Registrar in Psychiatry Foundation Trust South London and Maudsley NHS London, UK Foundation Trust London, UK Dr Robin Kumar MBBS BSc (Hons) FRCA Consultant Neuroanaesthetist Dr Graham Fleming MBBS FRACGP King’s College Hospital FCEM London, UK Consultant in Emergency Medicine King’s College Hospital Prof Anne Lingford-Hughes MA PhD BM London, UK BCh FRCPsych Professor of Addiction Biology Prof Guy Goodwin FMedSci Imperial College London Emeritus Professor of Psychiatry and Department of Psychiatry Hon Consultant Psychiatrist University of Oxford CNWL NHS Foundation Trust Oxford, UK London, UK Prof Jeremy Hall MA MB BChir MPhil PhD Dr James MacCabe BSc MB BS MSc MRCPsych FRCPsych PhD Director Reader in the Epidemiology of Psychosis Neuroscience and Mental Health Research Institute of Psychiatry, Psychology and Institute Neuroscience Cardiff University King’s College London Cardiff, UK London, UK viii Contributors Prof R Hamish McAllister-Williams BSc MB Dr Tabish Saifee MRCP PhD ChB PhD MD FRCPsych Consultant Neurologist and Senior Clinical Professor of Affective Disorders Lecturer Institute of Neuroscience The National Hospital for Neurology and Newcastle University Neurosurgery Newcastle upon Tyne, UK London, UK Dr John DC Mellers MBBS (Melbourne) Dr Hugh Selsick BSc (Hon) MBBCh MRCPsych Consultant in Psychiatry and Sleep Medicine Honorary Consultant Psychiatrist Insomnia Clinic Maudsley Hospital Royal London Hospital for Integrated Institute of Psychiatry, Psychology and Medicine and Sleep Disorder Centre Neuroscience Guy’s Hospital King’s College London London, UK London, UK Prof Donald Singer BMedBiol MD FRCP FBPharmacolS Dr Stirling Moorey BSc MBBS MA Professor of Clinical Pharmacology and FRCPsych Therapeutics Consultant Psychiatrist in CBT Fellowship of Postgraduate Medicine South London and Maudsley NHS London, UK Foundation Trust and Prof John-Paul Taylor MBBS(Hons) PhD Visiting Senior Lecturer MRCPsych Institute of Psychiatry, Psychology and Professor of Translational Dementia Neuroscience Research Institute of Neuroscience King’s College London and London, UK Honorary Consultant in Old Age Psychiatry Northumberland, Tyne and Prof John T O’Brien FMedSci Wear NHS Trust Foundation Professor of Old Age Newcastle-Upon-Tyne, UK Psychiatry Prof Peter Tyrer MD FRCPsych FMedSci Department of Psychiatry Emeritus Professor of Community Psychiatry University of Cambridge Imperial College London Cambridge, UK London, UK Mr Ian Osborne MPharm PgDip Dr Rachel Upthegrove MBBS FRCPsych PhD MRPharmS Reader in Psychiatry and Youth Mental Health Pharmacist Institute for Mental Health Pharmacy Department University of Birmingham Maudsley Hospital Birmingham, UK and Institute of Pharmaceutical Science Dr Dan Wilson MB BChir MRCP King’s College London Consultant Physician London, UK Department of Clinical Gerontology King’s College Hospital Dr Dene Robertson MB BS MRCGP London, UK MRCPsych Prof Allan H. Young MB ChB MPhil PhD Consultant Psychiatrist, Clinical Director FRCPsych FRCPC FRSB Behavioural and Developmental Clinical Director, Centre for Affective Disorders Academic Group Institute of Psychiatry, Psychology and South London and Maudsley NHS Neuroscience Foundation Trust King’s College London London, UK London, UK FOREWORD Doctors are generally people who like books. Throughout our long training, we spend many hours with them (or perhaps now their electronic equivalents) attempting to turn the lead of the prose contained therein into the gold of clinical knowledge which should be in every clinician’s brain as a bedrock of practice. However, our need to refresh and update this knowledge base never really ends for the active clinician, in training or not. To fill this need, many guidelines are available, but recently some of these have been bedevilled with controversy and have drifted somewhat from being the handy aid which the busy trainee and clinician requires. This fate has not befallen the British Association for Psychopharmacology Guidelines which remain as relevant and valued as ever for the guidance that they offer to the reader. The BAP Guidelines are based on expert opinion and high-quality evidence, are revised frequently and are free to download. The BAP Guidelines now also form the underpinning of evidence for this volume. The authors have worked hard to reconcile the mass of evidence with the need for brevity and have succeeded in this demanding task to produce a helpful text which all clinicians will find useful. This is to be greatly welcomed as such a practical compendium as the Pocket Prescriber Psychiatry will greatly aid the prescriber in psychiatry and find a welcome home in many pockets. Professor Allan Young MB ChB, MPhil, PhD, FRCPsych, FRCPC, FRSB President, British Association for Psychopharmacology
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