(c) 2015 Wolters Kluwer. All Rights Reserved. P o c k e t Notebook Pocket Obstetrics and GynecOlOGy Edited by K. Joseph hurt, MD, phD Assistant Professor Department of obstetrics and Gynecology University of Colorado School of Medicine (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-FM_i-xiv.indd 1 26/05/14 4:29 PM Acquisitions Editor: Jamie M. elfrank Product Development Editor: Ashley Fischer Freelance Development Editor: Sarah Granlund Production Project Manager: bridgett Dougherty Creative Director: Doug Smock Marketing Manager: Stephanie Manzo Manufacturing Coordinator: beth Welsh Prepress Vendor: Aptara, Inc. Copyright © 2015 Wolters kluwer Health All rights reserved. this book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. to request permission, please contact Wolters kluwer Health at two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at [email protected], or via our website at lww.com (products and services). 9 8 7 6 5 4 3 2 1 Printed in China Library of congress cataloging-in-Publication Data Pocket obstetrics and gynecology / edited by k. Joseph Hurt. p. ; cm. – (Pocket notebook series) ISbN 978-1-4511-4605-9 (paperback) I. Hurt, k. Joseph., editor. II. Series: Pocket notebook. [DNLM: 1. Genital Diseases, Female–diagnosis–Handbooks. 2. Diagnosis, Differential– Handbooks. 3. obstetrics–Handbooks. WP 39] RG107 618.1′075–dc23 2014017349 Care has been taken to confirm the accuracy of the information presented and to describe generally accepted practices. However, the author(s), editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the publication. Application of this information in a particular situation remains the professional responsibility of the practitioner; the clinical treatments described and recommended may not be considered absolute and universal recommendations. the author(s), editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accordance with the current recom- mendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. this is particularly important when the recommended agent is a new or infrequently employed drug. Some drugs and medical devices presented in this publication have Food and Drug Administration (FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug or device planned for use in his or her clinical practice. LWW.com (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-FM_i-xiv.indd 2 26/05/14 4:29 PM CONTENTS Contributing Authors ix Preface xiii Foreword xiv Well Woman Visit and Primary Care Shilpa Iyer, Kavita Shah Arora, Heather A. Walker, K. Joseph Hurt, and Maryam Guiahi Well-woman (Annual) Exam 1-1 Benign Breast Disease 1-2 Breast Cancer 1-4 Cervical Cancer Screening 1-5 Lipids & Cholesterol 1-7 Obesity 1-8 Osteoporosis 1-9 Skin Cancer Screening 1-11 Domestic Violence 1-12 Substance Abuse 1-13 Depression and Psychiatric Disease Screening 1-14 Contraception and Sterilization 1-15 Emergency Contraception (EC) 1-17 Vaccinations 1-17 Women’s Health Epidemiology and Research 1-18 emergenCy room Lauren May, Marguerite Palisoul, Caryn Dutton, and Roxanne Vrees Imaging in OBGYN 2-1 Ultrasound in Early Pregnancy 2-2 Acute Pelvic Pain 2-2 Ectopic Pregnancy 2-3 Ovarian Cysts 2-5 Adnexal Torsion 2-6 Pelvic Inflammatory Disease (PID) 2-7 Acute Uterine Bleeding 2-8 Spontaneous Abortion (SAB) 2-8 Trauma in Pregnancy 2-10 oPeratiVe oB-gyn Considerations Brett Einerson, Sherif El-Nashar, David Shalowitz, and Sarah L. Cohen Perioperative Patient Management 3-1 Postoperative Fever 3-5 Surgical Site Infections (SSI) 3-5 Perioperative DVT/PE 3-6 Sepsis 3-7 Perioperative Oliguria 3-8 Postoperative Ileus 3-9 Bowel Obstruction 3-9 Complications of Laparoscopy 3-10 Complications of Hysteroscopy 3-11 oB anesthesia Annalisa Post, Laura Goetzl Gynecologic Anesthesia 4-1 Parenteral Analgesia in Obstetrics 4-1 Neuraxial Anesthesia in Obstetrics 4-2 (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-R1-FM_i-xiv.indd 3 05/11/14 3:40 PM Local Anesthetics in obstetrics 4-5 Nonpharmacologic Analgesia in obstetrics 4-6 General Anesthesia in obstetrics 4-6 Postoperative Pain Management 4-6 generaL gynecoLogy Alexis May Tran, Teresa M. Walsh, and Sarah Appleton Vulvovaginitis 5-1 bartholin Gland Cyst and Abscess 5-2 Uterine Fibroids 5-2 Adenomyosis 5-4 endometriosis 5-4 Recurrent Abnormal Uterine bleeding (AUb) 5-6 Postmenopausal bleeding 5-7 Dysmenorrhea 5-8 Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Syndrome (PMS) 5-10 Chronic Pelvic Pain 5-10 Vestibulodynia 5-11 Female Sexual Dysfunction 5-12 Menopause 5-13 Hormone therapy 5-14 Pregnancy termination 5-16 PeDiatric anD aDoLescent gynecoLogy Jessica Opoku-Anane, Emily Petersen, and Tricia Huguelet Puberty 6-1 Precocious Puberty 6-2 Delayed Puberty 6-3 Amenorrhea 6-5 Androgen Insensitivity Syndrome 6-8 Congenital Adrenal Hyperplasia (CAH) 6-11 PeLVic surgery anD urogynecoLogy Catherine Hudson, Emily Prendergast, Kathleen A. Connell, and Lieschen H. Quiroz Physiology and Mechanisms of Micturition 7-1 Physiology and Mechanisms of Defecation 7-1 Pelvic organ Prolapse (PoP) 7-1 Urinary Incontinence 7-4 overactive bladder and Urge Incontinence 7-5 Stress Incontinence 7-6 overflow Incontinence 7-6 bypass Incontinence and Urogenital Fistulae 7-7 Interstitial Cystitis 7-7 Anal Incontinence 7-8 infertiLity Shweta Bhatt, Manuel Doblado, Laxmi A. Kondapalli, and Mary Ellen Pavone Infertility evaluation 8-1 Premature ovarian Insufficiency (PoI) 8-2 Polycystic ovarian Syndrome (PCoS) 8-2 tubal Factor Infertility 8-3 Recurrent Pregnancy Loss (RPL) 8-4 (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-FM_i-xiv.indd 4 26/05/14 4:29 PM Müllerian Anomalies 8-4 Male Factor Infertility 8-8 ovulation Induction and Assisted Reproduction 8-9 Fertility Preservation 8-10 Preimplantation Genetic testing 8-11 ovarian Hyperstimulation Syndrome (oHSS) 8-11 PrenataL care Sarah Rae Easter, Julia Drose, Emily Todd, and Sharon Phelan Routine Prenatal Visits 9-1 Nutrition in Pregnancy 9-3 Clinical Pelvimetry 9-4 Common Prenatal Complaints 9-5 Fetal Ultrasound: Anatomy and echocardiography 9-6 Congenital Anomalies 9-7 Genetic Screening 9-11 Amniocentesis and Chorionic Villus Sampling (CVS) 9-12 normaL LaBor anD DeLiVery David Shalowitz, Amy Nacht, and Sara Mazzoni Antenatal Fetal testing 10-1 Fetal Lung Maturity testing by Amniocentesis 10-2 Newborn Respiratory Distress 10-2 Group b Streptococcal Disease 10-3 Spontaneous Labor and Delivery 10-4 Induction of Labor (IoL) 10-5 Intrapartum Fetal Monitoring 10-7 operative Vaginal Delivery 10-11 Vaginal birth After Cesarean 10-12 Fetal Cord blood Gas Analysis 10-13 Routine Postpartum Care 10-13 breastfeeding 10-14 Affiliated obstetrical Providers 10-15 comPLicateD Pregnancy anD DeLiVery Lisa Gill, Alexandria J. Hill, Paul Wexler, and Jamie Bastek Gestational Hypertensive Disorders 11-1 Hydrops Fetalis 11-2 Intrauterine Growth Restriction 11-3 Multiple Gestation 11-4 Cervical Insufficiency/Short Cervix 11-5 Preterm Premature Rupture of Membranes 11-6 Preterm Labor 11-7 Postpartum Hemorrhage (PPH) 11-8 Placental Abruption 11-11 Placenta Previa 11-12 Vasa Previa 11-13 Placenta Accreta 11-13 Uterine Inversion 11-14 Amniotic Fluid embolism 11-14 Malpresentation 11-15 Fetal Meconium 11-15 Chorioamnionitis 11-16 endomyometritis 11-16 (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-FM_i-xiv.indd 5 26/05/14 4:29 PM carDioLogy anD carDioVascuLar Disease Catherine Albright, Meghan Donnelly Cardiovascular Disease in Pregnancy 12-1 Cardiovascular Changes in Pregnancy 12-1 Chronic Hypertension (CHtN) 12-2 Hypertensive Crisis 12-4 Pregnancy-Related Hypertension 12-5 Coronary Artery Disease/Acute Coronary Syndrome 12-8 Pulmonary Hypertension 12-9 Valvular Heart Disease 12-10 Peripartum Cardiomyopathy 12-12 PuLmonary David Shalowitz, Abdulrahman Sinno, and M. Camille Hoffman Pulmonary Function testing 13-1 Respiratory Changes in Pregnancy 13-2 Arterial blood Gas (AbG) Analysis 13-3 Pneumonia 13-4 Pulmonary edema 13-5 Influenza in Pregnancy 13-5 Asthma and Pregnancy 13-6 Anaphylaxis 13-7 nePhroLogy anD urinary tract Megan Barrett, Gina Northington Urinary System Changes in Pregnancy 14-1 Acute Renal Failure (ARF) 14-1 Chronic Renal Failure 14-3 Urinary tract Infection (UtI) 14-4 Pyelonephritis 14-6 Nephrolithiasis 14-7 Fluids and electrolytes 14-8 gastroenteroLogy Terri Huynh, Roxanne Vrees Gastrointestinal Changes in Pregnancy 15-1 Cholelithiasis 15-1 Cholecystitis 15-1 Appendicitis 15-2 Pancreatitis 15-3 Irritable bowel Syndrome (IbS) 15-3 Inflammatory bowel Disease 15-4 Viral Hepatitis 15-6 Intrahepatic Cholestasis of Pregnancy (ICP) 15-8 HeLLP Syndrome 15-9 Acute Fatty Liver of Pregnancy (AFLP) 15-10 total Parenteral Nutrition (tPN) 15-10 hematoLogy Todd J. Stanhope, Sasha Andrews Hematologic Changes of Pregnancy 16-1 Anemia 16-1 Hemoglobinopathies 16-3 thrombocytopenia (Plt <150000/mL) 16-4 (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-FM_i-xiv.indd 6 26/05/14 4:29 PM Venous thromboembolic Disease 16-6 Perioperative Vte Prevention 16-9 thrombophilia evaluation 16-10 Coagulopathies 16-11 Antiphospholipid Antibody Syndrome (APS) 16-12 Alloimmunization 16-13 blood Products for Hemorrhage and Critical Care 16-15 enDocrinoLogy Juan Alvarez, Amy Schutt, K. Joseph Hurt, and Terry Harper Hormonal Regulation 17-1 type I Diabetes Mellitus 17-2 Diabetic ketoacidosis (DkA) 17-3 type II Diabetes Mellitus 17-4 Hyperosmolar Hyperglycemic State 17-5 Diabetes in Pregnancy 17-5 Gestational Diabetes (GDM) 17-7 Hypothyroidism 17-8 Hyperthyroidism 17-9 Adrenal Disorders 17-10 Hyperandrogenism 17-12 Hirsutism 17-13 Parathyroid Disorders 17-14 Pituitary Disorders 17-15 neuroLogy Ponnila Marinescu, K. Joseph Hurt Headache (HA) 18-1 Migraine 18-2 Seizure Disorders 18-3 eclampsia 18-5 Stroke in Pregnancy 18-6 Cerebral Venous thrombosis 18-6 Multiple Sclerosis in Pregnancy 18-7 Neuropathies in Pregnancy 18-8 DermatoLogy Sumer Allensworth, K. Joseph Hurt, Crystal Adams Dermatologic Changes in Pregnancy 19-1 Lichen Sclerosus 19-2 Lichen Simplex Chronicus 19-3 Lichen Planus 19-3 Seborrheic Dermatitis 19-4 Hidradenitis Suppurativa 19-5 Fox-Fordyce Disease 19-5 Gyn-Derm Cysts 19-6 Common Dermatologic Manifestations of Systemic Disease 19-6 infectious Disease Leo Han, Michelle Khan HIV/AIDS in Women 20-1 toRCH Infections 20-2 other Infections in Pregnancy 20-4 Human Papilloma Virus (HPV) 20-5 Syphilis 20-7 (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-FM_i-xiv.indd 7 26/05/14 4:29 PM Molluscum Contagiosum 20-8 Chancroid 20-9 Pubic Lice 20-9 Genital Ulcers 20-10 gynecoLogic oncoLogy Mariam Al-Hilli, Erin Medlin, Kari Ring, Leigh A. Cantrell, and Ritu Salani types of Hysterectomy 21-1 Cervical Cancer 21-2 Uterine Cancer 21-4 epithelial ovarian Cancer (eoC) 21-7 Germ Cell tumors 21-8 Sex Cord-Stromal tumors 21-10 Vaginal Cancer 21-11 Vulvar Cancer 21-12 Gestational trophoblastic Neoplasia 21-14 Chemotherapy 21-17 Radiation therapy 21-18 aPPenDix: oB-gyn anatomy Primer 22-1 Sherif El-Nashar aPPenDix: common ProceDures anD surgeries 23-1 Sherif El-Nashar, David Shalowitz aPPenDix: Drug reference 24-1 Natalie Karp aPPenDix: acLs aLgorithms 25-1 aPPenDix: nrP aLgorithm 26-1 aBBreViations 27-1 inDex I-1 (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-FM_i-xiv.indd 8 26/05/14 4:29 PM CONTRIBUTING AUTHORS crystal adams, mD Jamie Bastek, mD, msce Assistant Professor Assistant Professor obstetrics & Gynecology Maternal Fetal Medicine University of Colorado obstetrics & Gynecology Aurora, Colorado University of Pennsylvania Philadelphia, Pennsylvania catherine m. albright, mD Section Editor shweta Bhatt, mD Resident, obstetrics & Gynecology Resident, obstetrics & Gynecology brown University Northwestern University Providence, Rhode Island Chicago, Illinois mariam al-hilli, mD Leigh a. cantrell, mD, msPh Resident, obstetrics & Gynecology Assistant Professor Mayo Clinic Gynecologic oncology Rochester, Minnesota obstetrics & Gynecology University of Virginia sumer k. allensworth, mD Charlottesville, Virginia Resident, obstetrics & Gynecology University of Colorado sarah L. cohen, mD, mPh Aurora, Colorado Instructor Minimally Invasive Surgery Juan P. alvarez, mD obstetrics & Gynecology Resident, Gynecology & obstetrics Harvard Medical School emory University boston, Massachusetts Atlanta, Georgia kathleen a. connell, mD sasha e. andrews, mD Associate Professor Fellow Female Pelvic Medicine & Maternal Fetal Medicine Reconstructive Surgery obstetrics & Gynecology obstetrics & Gynecology University of Colorado University of Colorado Aurora, Colorado Aurora, Colorado sarah appleton, mD manuel a. Doblado, mD, ma Senior Instructor Resident, obstetrics & Gynecology obstetrics & Gynecology University of Colorado University of Colorado Aurora, Colorado Aurora, Colorado meghan Donnelly, mD kavita shah arora, mD, mBe Assistant Professor Section Editor Maternal Fetal Medicine Resident, obstetrics & Gynecology obstetrics & Gynecology Northwestern University University of Colorado Chicago, Illinois Aurora, Colorado megan r. Barrett, mD Julia a. Drose, rDms, rDcs, Section Editor rVt Resident, obstetrics & Gynecology Associate Professor, Radiology University of Virginia University of Colorado Charlottesville, Virginia Aurora, Colorado (c) 2015 Wolters Kluwer. All Rights Reserved. LWBK1354-FM_i-xiv.indd 9 26/05/14 4:29 PM
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