PHARMACOTHERAPY Edited by Farid Badria Pharmacotherapy Edited by Farid Badria Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. As for readers, this license allows users to download, copy and build upon published chapters even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas contained in the book. Publishing Process Manager Ivona Lovric Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published June, 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from [email protected] Pharmacotherapy, Edited by Farid Badria p. cm. ISBN 978-953-51-0532-9 Contents Preface IX Section 1 In Vivo Imaging – New Diagnostic and Therapeutic Approach 1 Chapter 1 Small Animal Imaging in Development of New Generation Diagnostic and Therapeutic Agents 3 Tuulia Huhtala and Ale Närvänen Section 2 Earthquake Medical Management 23 Chapter 2 Rational Drug Use in Medical Response to an Earthquake 23 Ling-li Zhang, Yi Liang, Li-nan Zeng and Die Hu Section 3 Cognitive and Psychology Management 39 Chapter 3 Integration of Pharmacological and Psychosocial Treatment for Schizophrenia in Mexico: The Case of a Developing Country Proposal 37 Marcelo Valencia, Alejandro Diaz and Francisco Juarez Chapter 4 Nicotine Addiction: Role of the Nicotinic Acetylcholine Receptors Genetic Variability in Knowledge, Prevention and Treatment 69 Candida Nastrucci and Patrizia Russo Chapter 5 Psychiatric Drugs in Medical Practice 81 María-José Martín-Vázquez Section 4 Up-to-Date in Anti-Inflammatory Therapy 113 Chapter 6 State of the Art of Anti-Inflammatory Drugs 115 Túlio Ricardo Couto de Lima Souza, Graziella Silvestre Marques, Amanda Carla Quintas de Medeiros Vieira and Juliano Carlo Rufino de Freitas VI Contents Chapter 7 House Dust Mite Immunotherapy in Iraqi Patients with Allergic Rhinitis and Asthma 141 Abdulghani Mohamad Alsamarai, Amina Hamed Ahmad Alobaidi, Sami Mezher Alrefaiei and Amar Mohamed Alwan Section 5 Up-to-Date in Antihypertensive Therapy 155 Chapter 8 Efficacy of Aliskiren/Hydrochlorothiazide Combination for the Treatment of Hypertension: A Meta-Analytical Revision 157 Manuel Morgado, Sandra Rolo and Miguel Castelo-Branco Section 6 Up-to-Date in Ulcer with Venous Origin Therapy 179 Chapter 9 LavTIME – A Brand-New Treatment Method of Lasting Wounds – A Multi-Centre Randomized Double-Blind Study on Effectiveness of Polyhexanide and Betaine in Ulcers’ Healing with Venous Origin 181 Z. Rybak, G Krasowski, R. Wajda and P. Ciesielczyk Preface Though Pharmacotherapy continues to be complex, it never ceases to be interesting. Pharmacotherapy is frequently combined with other treatment methods, such as physical therapy and dietotherapy. Drugs are often used in various combinations. We have two major objectives in writing this book; firstly, to strike a balance between developments in Pharmacotherapy research and the facts that researchers must absorb, and secondly, to link scientific advances with clinical practice so that the management of diseases can be based on sound physiological concepts. Therefore, this book is a book that everybody involved in Pharmacotherapy must have. Each chapter has been reviewed and revised and new authors have brought up‐to‐date research to make the book better informative, illustrative, and easy to read. The intent of this book is to provide an overview of current conceptualizations of Pharmacotherapy. The book focuses on three major areas; diagnosis, treatment, and prevention for a wide array of diseases; Cognitive and Psychological disorders (Schizophrenia and Nicotine addiction), Inflammatory disorders (New Chemical anti‐ inflammatory and Immunotherapy), updated antihypertensive therapy and healing of ulcers with venous origin. A separate chapter is dedicated to the rationality of drug use in earthquake injuries. The last chapter deals with Imaging of potential therapeutic or diagnostic agents in animal models in the early stage of research. This is an important step towards pre‐clinical and clinical trials in human. We hope this book is useful to a wide range of people, from students first learning about Pharmacotherapy, to advanced clinicians and researchers who are looking for a review of current treatments and conceptualizations of the condition. It is our hope that this book may motivate readers to approach the evidence on Pharmacotherapy with an open mind, and thereby spark an interest in making further contributions to the current scientific debate and treatment development efforts. Farid A. Badria Prof. and Head of Pharmacognosy Department Faculty of Pharmacy, Mansoura University, Mansoura, Egypt Section 1 In Vivo Imaging – New Diagnostic and Therapeutic Approach
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