Personalized Medicine - Dr Amy Yasko

211 Pages·2007·17.28 MB·English

by  Amy Yasko

Microbes, Metals and
Methylation
Dr. Amy Yasko
April 2005
MICROBES
METALS METHYLATION
At least 15% of the general population has a
genetic enzyme defect (C-to-T mutation of
nucleotide 677 of the MTHFr gene) that causes
elevated homocysteine. High levels of
homocysteine are correlated with heart disease, as
well as with Alzheimer’s disease. Moreover, higher
risks of neural tube malformations have been
attributed to this mutation. An additional genetic
change in the MTHFr gene, known as A1298C,
also results in a lowered enzymatic activity. It is
essential when screening, to use a test that looks
for BOTH of these mutations, the C677T and the
A1298C.
Saliva and blood tests are available to determine if
you have this mutation. According to Dr. Richard
Kunin up to 80%-90% of the patients he sees carry
one or the other of these MTHFr mutations. In Dr.
Yasko’s practice, she has seen an exceedingly
high correlation between children with this
mutation and autism and ADD, ADHD. The
pathways involved with this mutation are
understood, and nutritional supplements are
available that bypass the genetic defect.
(Presentation: Vitamin Related Mutations, Jan.,
2004).)
Case study
• Severely autistic
• MTHFr
• Negative provoked urine
• RNA based protocol with EDTA
Provoked urine tests do not
always reflect the actual body
burden of heavy metals,
especially in the presence of
chronic infection.
DMSA Provoked Urine
June 4, 2001
NO MERCURY
DMSA Provoked Urine
July 16,2001
NO MERCURY
DMSA Provoked Urine
August 15, 2001
NO MERCURY