v a d e m e c u m Perioperative Care in Cardiac Anesthesia and Surgery Davy C.H. Cheng, M.D. Tirone E. David, M.D. Toronto General Hospital Peter Munk Cardiac Centre . L A N D E S B I O S C I E N C E GEORGETOWN, TEXAS U.S.A. v a d e m e c u m Perioperative Care in Cardiac Anesthesia and Surgery Davy C.H. Cheng, M.D. Tirone E. David, M.D. Toronto General Hospital Peter Munk Cardiac Centre L A N D E S B I O S C I E N C E AUSTIN, TEXAS U.S.A. VADEMECUM Perioperative Care in Cardiac Anesthesia and Surgery LANDES BIOSCIENCE Austin Copyright © 1999 Landes Bioscience All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Printed in the U.S.A. Please address all inquiries to the Publisher: Landes Bioscience, 810 S. Church Street, Georgetown, Texas, U.S.A. 78626 Phone: 512/ 863 7762; FAX: 512/ 863 0081 ISBN: 1-57059-527-5 Library of Congress Cataloging-in-Publication Data Perioperative care in cardiac anesthesia and surgery/ [edited by] Davy C.H. Cheng, Tirone E. David. p.cm. "Vademecum." Includes bibliographical references and index. ISBN 1-57059-527-5 (alk. paper) 1. Heart--Surgery--Patients--Medical care--Handbooks, manuals, etc. 2. Therapeutics, Surgical--Handbooks, manuals, etc. 3. Operating room nursing--Handbooks, manuals, etc. 4. Postoperative care--Handbooks, manuals, etc. I. Cheng, Davy C. H. II. David, Tirone E. [DNLM: 1. Perioperative Care--methods. 2. Coronary Disease--surgery. 3. Cardiac Surgical Procedures--methods. WO 178 H2356 1999] RD598.H286 1999 617.4'12--dc21 DNLM/DLC 98-50222 for Library of Congress CIP While the authors, editors, sponsor and publisher believe that drug selection and dosage and the specifications and usage of equipment and devices, as set forth in this book, are in accord with current recommendations and practice at the time of publication, they make no warranty, expressed or implied, with respect to material described in this book. In view of the ongoing research, equipment development, changes in governmental regula- tions and the rapid accumulation of information relating to the biomedical sciences, the reader is urged to carefully review and evaluate the information provided herein. Dedication To the students, residents, and fellows of cardiac anesthesia and surgery at Toronto General Hospital, University of Toronto. Contents I. Peter Munk Cardiac Centre, Toronto General Hospital 1. The Toronto General Hospital Cardiac Surgical Program....................................................1 Tirone E. David 2. Fast Track Cardiac Surgical Program..................................3 Davy C.H. Cheng Introduction..................................................................................................3 Risk Stratification in Fast Track Cardiac Surgery........................................3 Medical and Economic Implications...........................................................4 Fast Track Cardiac Surgery Team.................................................................7 3. Preoperative Assessment......................................................8 Tirone E. David, Susan Kerwin-Lenkei, John Bradley Basic Evaluation............................................................................................8 Preadmission Tests......................................................................................10 Assessing the Risk and Benefit of Surgery.................................................10 Informed Consent.......................................................................................12 The Pre-admission Clinic...........................................................................12 Preoperative Medication Order..................................................................12 II. Anesthesia and Cardiopulmonary Bypass Management 4. Early Extubation Anesthesia..............................................14 Davy C.H. Cheng Preoperative.................................................................................................14 Intraoperative..............................................................................................14 Postoperative...............................................................................................15 5. Perioperative Monitoring and Intraoperative Echocardiography..............................17 Corey Sawchuk, Harry Rakowski Standard Monitors......................................................................................17 Central Venous Monitoring (CVP)............................................................17 Swan-Ganz Catheterization........................................................................18 Transesophageal Echocardiography (TEE)................................................19 Mitral Valve Repair......................................................................................20 Aortic Valve Repair......................................................................................21 6. Weaning from Cardiopulmonary Bypass.........................23 Annette Vegas Weaning Techniques...................................................................................23 Theory and Practice....................................................................................25 Individual Agents........................................................................................27 Summary.....................................................................................................30 7. Blood Conservation and Transfusion Requirement........31 Jacek M. Karski Introduction................................................................................................31 Post-CPB Coagulopathy.............................................................................31 Predictors of Postoperative Bleeding .........................................................31 Prevention of the Postoperative Blood Loss..............................................32 Antifibrinolytics..........................................................................................33 Blood Product Administration...................................................................35 Summary.....................................................................................................36 8. Anesthesia for Special Cardiac Surgical Procedures........38 Annette Vegas Anesthesia for Minimally Invasive Coronary Artery Bypass....................38 Anesthesia for Partial Left Ventriculectomy (PLV)....................................41 9. Anesthetic Management of Diseases Affecting Cardiopulmonary Bypass..................................44 Ramiro Arellano Diabetes Mellitus.........................................................................................44 Renal Insufficiency......................................................................................44 Sickle Cell Trait and Disease.......................................................................46 Cryoproteins................................................................................................47 10. Malignant Hyperthermia...................................................50 Jane E. Heggie Introduction................................................................................................50 Malignant Hyperthermia Crisis.................................................................50 Postcrisis Management...............................................................................51 Elective Management of Malignant Hyperthermia Susceptible Patients.....................................................................................52 Preoperative.................................................................................................52 Intraoperative..............................................................................................53 Postoperative...............................................................................................53 11. Combined Cardiac and Thoracic Surgery ........................54 Peter Slinger Controversies...............................................................................................54 Presentation.................................................................................................55 Preoperative Evaluation..............................................................................55 Anesthetic Technique..................................................................................57 Combined Procedures.................................................................................58 Postoperative Analgesia...............................................................................59 12. Anesthesia for Intrathoracic Transplantation..................60 Karen M. McRae Introduction................................................................................................60 Lung Transplantation..................................................................................61 Heart Transplant.........................................................................................65 Heart-Lung Transplant...............................................................................69 Nitric Oxide.................................................................................................69 13. Heparin Associated Thrombocytopenia and Alternatives to Heparin...............................................71 Patricia McNama, Annette Vegas Introduction................................................................................................71 Heparin........................................................................................................71 Heparin Associated Thrombocytopenia....................................................72 Diagnosis.....................................................................................................73 Management................................................................................................73 Alternatives to Heparin for CPB................................................................74 14. Cardiopulmonary Bypass Technique................................78 TTH Perfusionists Introduction................................................................................................78 Circuit..........................................................................................................78 Circulatory Changes During CPB..............................................................79 Methods of Adjusting BP............................................................................80 Pump Flow vs. Pressure (MAP)..................................................................80 Pulsatile vs. Nonpulsatile Flow...................................................................81 Hypothermia vs. Normothermia Bypass...................................................81 ABG Analysis Alpha (α) vs. pH Stat...........................................................83 15. Circulatory Arrest and Neuroprotection..........................84 Christopher M.S. Feindel, Ludwig Fedorko Introduction................................................................................................84 Indications...................................................................................................84 Technique of Circulatory Arrest.................................................................85 Retrograde Cerebral Perfusion...................................................................86 Pharmaceutical and Other Neuroprotective Adjuncts..............................86 Acid/Base Control.......................................................................................87 Glucose Control..........................................................................................87 Temperature Monitoring and Rewarming Phase......................................87 Pharmacotherapy........................................................................................87 16. Hemoconcentration and Hemodialysis During CPB ......89 Teraze McDougall, Mary Scholz Hemoconcentration (Ultra-filtration).......................................................89 Hemodialysis...............................................................................................91 17. Intra-Aortic Balloon Pump................................................93 Arthur Melo, Mindy Madonik, Annette Vegas Mechanism of Action and Role..................................................................93 Monitoring..................................................................................................94 Weaning and Removal................................................................................94 Balloon Operation ......................................................................................95 Conventional Timing..................................................................................95 Trouble Shooting IABP...............................................................................97 III. Surgical Technique and Postoperative Consideration 18. Aortocoronary Bypass: Surgical Technique Including Cannulation Techniques...................................99 Anthony Ralph-Edwards Aortocoronary Bypass Surgery...................................................................99 Cannulation Techniques...........................................................................102 19. Myocardial Protection......................................................106 Michael A. Borger, Richard D. Weisel Introduction..............................................................................................106 Cardioplegia Composition.......................................................................106 Cardioplegia Temperature........................................................................107 Cardioplegia Delivery...............................................................................108 Future Directions......................................................................................110 20. Surgery of Heart Valve, the Aortic Root, Ascending Thoracic Aorta and Transverse Arch ............111 Tirone E. David Aortic Valve Repair....................................................................................112 Aortic Valve Replacement.........................................................................112 Mitral Valve Repair....................................................................................116 Mitral Valve Replacement.........................................................................117 Tricuspid Valve Repair...............................................................................118 Tricuspid Valve Replacement....................................................................118 Maze Procedure for Atrial Fibrillation.....................................................119 Surgery for Chronic Ascending Aortic Aneurysm...................................119 Surgery for Mega-Aorta Syndrome..........................................................120 Surgery for Acute Type A Aortic Dissection............................................120 21. Heart Transplantation......................................................122 Christopher M.S. Feindel, Heather Ross, Annette Vegas Recipient....................................................................................................122 Donors.......................................................................................................124 Surgical Technique for Donor Harvest....................................................125 Surgical Technique for Orthotopic Heart Transplant.............................125 Immediate Postoperative Management...................................................127 Immunosuppression.................................................................................127 Complications...........................................................................................128 22. Adult Congenital Heart Surgery......................................130 Nancy C. Poirier, Glen S. Van Arsdell, William G. Williams Atrial Septal Defect (ASD)........................................................................131 Ventricular Septal Defects (VSD).............................................................133 Patent Ductus Arteriosis (PDA)...............................................................135 Coarctation................................................................................................136 Tetralogy of Fallot (TOF)..........................................................................138 Single Ventricle (Fontan Operation)........................................................140 Hypertrophic Obstructive Cardiomyopathy (HOCM)...........................143 23. Ventricular Aneurysm Resection.....................................146 Lynda L. Mickleborough Left Ventricular Aneurysm........................................................................146 Ventricular Arrhythmias, Mapping, Ventricular Tachycardia Ablation.............................................................147 24. Combined Cardiac and Vascular Surgery.......................148 Charles M. Peniston Carotid Artery Surgery and Cardiac Surgery...........................................148 Combined Coronary Artery Bypass with Abdominal Aortic Aneurysm Repair...............................................149 25. Minimally Invasive Cardiac Surgery...............................151 Robert J. Cusimano Indications.................................................................................................151 Operative Technique.................................................................................152 Stabilization of the Heart..........................................................................153 Heart Rate Control....................................................................................153 Postoperative Care.....................................................................................154 26. Partial Left Ventriculectomy (PLV).................................155 Robert J. Cusimano Indications.................................................................................................155 Operative Technique.................................................................................156 Postoperative Care.....................................................................................156 27. AICD and Pacemakers Insertion.....................................158 Charles M. Peniston Automatic Implantable Cardioverter Defibrillator (AICD)...................158 Pacemakers................................................................................................159 28. Ventricular Assist Devices (VAD)....................................163 Gideon I. Cohen Commonly Utilized Ventricular Assist Devices (VAD)...........................163 Indications for Left Ventricular Assist Device (LVAD) Implantation.....163 Absolute and Relative Contraindications to LVAD Implantation..........164 Biventricular VAD Indications.................................................................165 Semi-Implantable/Pericorporeal VAD.....................................................165 Perioperative Considerations...................................................................166 LVAD Complications................................................................................168 Myocardial Recovery after LVAD Placement...........................................168 Total Artificial Heart.................................................................................169 29. Lung and Heart-Lung Transplantation...........................170 Shaf H. Keshavjee Introduction..............................................................................................170 Surgical Technique....................................................................................170 Postoperative Care.....................................................................................173 IV. Post-cardiac Surgical Unit Management 30. Routine CVICU Care: Early Extubation to Discharge...176 Annette Vegas, Davy C. H. Cheng Early Tracheal Extubation and Process of Care.......................................176 CVICU—A Variable Care Unit ................................................................177 Admissions................................................................................................177 Routine Postoperative Course..................................................................179 Common Management Strategies............................................................179 Unstable Patients and Chest Re-openings...............................................181 Medical Rounds.........................................................................................181 Discharges..................................................................................................182 Delegated Acts and Procedures ................................................................182 31. Analgesia Techniques.......................................................184 Gerald O’Leary, Alan N. Sandler Introduction..............................................................................................184 Modalities..................................................................................................184 Common Problems...................................................................................186 32. Common Problems in the CVICU ..................................188 Annette Vegas Central Nervous System (CNS)................................................................188 Respiratory................................................................................................189 Cardiovascular...........................................................................................190 Gastrointestinal.........................................................................................193 Renal..........................................................................................................194 Hematologic..............................................................................................195 Metabolic...................................................................................................195 Infectious Disease......................................................................................200 V. Postoperative Complications Management 33. Chest Reopening...............................................................201 Terrence M. Yau Introduction..............................................................................................201 Incidence....................................................................................................201 Indications.................................................................................................201 Technique of Emergency Chest Reopening.............................................203 Outcomes...................................................................................................205 Summary...................................................................................................206
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