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ISSN: 0888-0018 VOLUME 10 T3393 Pediatric Hematology and Oncology JORGEN COHN, M.D. Editor-in-Chief Pediatric Hematology and Oncology EDITOR-IN-CHIEF Editorial Office: Jgrgen Cohn, M.D., Department of Paediatrics, University of Tromsg, The Health Jorgen Cohn, M.D. Studies Building, MH-Breivika, N-9037 Troms¢g, Nor- Department of Paediatrics, University way. Telephone 47-83-45708, Telefax 47-83-45740. Publishing, Advertising, and Production Offices: of Troms¢, The Health Studies Taylor & Francis, 1101 Vermont Ave., Suite 200, Building, MH-Breivika, N-9037 Washington, DC 20005, phone (202)289-2174, fax Troms¢, Norway (202)289-3665, Sarah E. Baker, Production Editor; or Taylor & Francis Ltd., Rankine Rd., Basingstoke, Hampshire RG24 OPR, UK. 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Oncology Information Service, and Cambridge Sci- @ Printed on acid-free paper, effective with Vol- entific Abstracts. ume 9, Number 1, 1992. CONTENTS OF VOLUME 10 Number 1 Editorial CYTOGENETIC ABNORMALITIES IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIAS © G. Schaison Annotation GROWTH HORMONE AND LEUKEMIA © julie Blatt Articles CONSTITUTIVE HETEROCHROMATIN POLYMORPHISMS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA Aspasia Tsezou, Sofia Kitsiou-Tzeli, Helen Kosmidis, Kalliopi Paidousi, Klea Katsouyanni, and Constantine Sinaniotis THALASSEMIA: LUNG FUNCTION WITH REFERENCE TO IRON STUDIES AND REACTIVE OXIDANT STATUS © David K. Luyt, Guy A. Richards, Herna Roode, RobertJ . Dowdeswell, AudreyJ . van Rensburg, and Stephanus G. Reinach Short Communications CYTOGENETIC ABNORMALITIES IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA © PD. Micallef-Eynaud, O. B. Eden, E. Grace, and P. M. Ellis MYCN AMPLIFICATION BY DIFFERENTIAL PCR © Simon N. Huddart, Jillian R. Mann, Angela G. McGukin, and Robin Corbett REVERSIBLE CARDIOPATHY AFTER ACCIDENTAL OVERDOSE OF MITOXANTRONE © SS. Hachimi-Idrissi, R. Schots, D. DeWolf, S. J. P. Van Belle, and J. Otten GROWTH HORMONE TREATMENT AND DEVELOPMENT OF MALIGNANCY: RECOMBINANT HUMAN GROWTH HORMONE DOES NOT INDUCE LEUKEMIA IN AKR/O-MICE © Anne Grete Bechensteen, Sverre Halvorsen, Michael Abdelnoor, and Anna Skottner TERATOMA ASSOCIATED WITH ENDODERMAL SINUS TUMOR O L.C.H. John, J. Kingston, and S. J. Edmondson LATE LEUKEMIC RELAPSE 10 YEARS FROM DIAGNOSIS IN A CHILD ON RECOMBINANT HUMAN GROWTH HORMONE © David L. Baker, Ursula R. Kees, P. James Price, and Michael L. N. Willoghby Report REPORT ON THE INTERNATIONAL WORKSHOP OF THE KIND PHILIPP FOUNDATION ON LATE EFFECTS AFTER BONE MARROW TRANSPLANTATION IN CHILDHOOD MALIGNANCIES OR. Dopfer and D. Niethammer Letters to the Editor CUTANEOUS RELAPSE IN A CHILD WITH ACUTE MIXED LEUKEMIA Affif Barbara, Luigi Besenzon, Alessandro Busca, Adalberto Brach del Prever, Roberto Miniero, Enrico Madon, Robin Foa; Marco Forni, and Maddalena Saitta LONG-TERM PREDNISOLONE THERAPY IN CHILDREN WITH IDIOPATHIC PULMONARY HEMOSIDEROSIS © Vaskar Saha, Edwin Ravikumar, Uma Khanduri, Anand Date, Joyce Ponnaiya, and P. Raghupathy RHABDOMYOSARCOMA OF THE ORBIT © PP. Schlienger Reply THE ROLE OF CHEMOTHERAPY, SURGERY, AND RADIOTHERAPY IN RHABDOMYOSARCOMA OF THE ORBIT © J. de Kraker Letters to the Editor VARIABLE PRESENCE OF CIRCULATING CYTOKINES IN PATIENTS WITH SPORADIC OR X-LINKED LYMPHOPROLIFERATIVE DISEASE WITH FATAL INFECTIOUS MONONUCLEOSIS © Motohiko Okano, Geoffrey M. Thiele, and David T. Purtilo GASTRIC PERFORATION IN NON-HODGKIN’S LYMPHOMA S. Attard-Montalto, J. E. Kingston, and O. B. Eden SUCCESSFUL USE OF PARTIAL SPLENIC EMBOLIZATION IN AN INFANT WITH AUTOIMMUNE HEMOLYTIC ANEMIA 7c SS. _Taniuchi, A. Fujita, Y. Iwamoto, K. Harima, and Y. Kobayashi CENTRAL NERVOUS SYSTEM DISEASE IN ACUTE LYMPHOBLASTIC LEUKEMIA © Giulio J. D’Angio POST-MONILIAL EXTENSIVE ESOPHAGEAL STRICTURE O Adel Ismail and Shaker Abdulla BOOK REVIEW ERRATUM Number 2 Editorial A HISTORICAL SKETCH OF PEDIATRIC HEMATOLOGY AND ONCOLOGY IN JAPAN © Fumio Bessho and Noboru Kobayashi T-LYMPHOCYTES IN CHILDHOOD LEUKEMIA © Yehuda L. Danon Annotation EPIPODOPHYLLOTOXINS AND SECONDARY LEUKEMIA © Richard B. Womer Articles THE ASSESSMENT OF SUBCLINICAL IFOSFAMIDE-INDUCED RENAL TUBULAR TOXICITY USING URINARY EXCRETION OF RETINOL-BINDING PROTEIN © Mahmoud Al Sheyyab, David Worthington, Robert Beetham, and Michael Stevens SERIAL STUDY OF T LYMPHOCYTES IN CHILDHOOD LEUKEMIA DURING REMISSION © Penny E. Lovat, John H. Robinson, Kevin P. Windebank, Jenny Kernahan, and J. Graham Watson Review Article HISTORY AND PRESENT STATE OF PEDIATRIC HEMATOLOGY AND ONCOLOGY IN TURKEY © Sinasi Ozsoylu Short Communications DYSKERATOSIS CONGENITA: UNUSUAL PRESENTING FEATURES WITHIN A KINDRED © Gian Luca Forni, Caterina Melevendi, Scilla Jappelli, and Alberto Rasore-Quartino TUMOR LYSIS SYNDROME COMPLICATING TREATMENT OF WIDESPREAD METASTATIC ABDOMINAL RHABDOMYOSARCOMA © Javed Khan and Valerie A. Broadbent THE USE OF TAPED PARENTAL INTERVIEWS TO IMPROVE COMMUNICATION WITH CHILDHOOD CANCER FAMILIES QO O. B. Eden, I. Black, and A. E. H. Emery MYELODYSPLASTIC SYNDROME FOLLOWING EPIPODOPHYLLOTOXIN THERAPY IN FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS © Jan-Inge Henter, Goran Elinder, Per-Olof Libeck, and Ake Ost INVASIVE ASPERGILLOSIS IN LEUKEMIC CHILDREN © Toshiji Shitara, Shin-ichiroh Yugami, Manabu Sotomatu, Yukio Oshima, Hiroko Ijima, Takayoshi Kuroume, and Mitsuomi Matsumoto Letters to the Editor CHILDHOOD MYELOFIBROSIS: Transformation to Acute Lymphoblastic Leukemia © Ruma Ray, G. Garewal, R. K. Marwaha, and Neelam Marwaha PERCUTANEOUS RETRIEVAL OF AN EMBOLIZED MEDIPORT CATHETER IN A PATIENT RECEIVING THERAPY FOR HODGKINS LYMPHOMA © Abraham Rothman and Faith H. Kung UNUSUAL CAUSE OF SIDEROPENIC ANEMIA IN CHILDHOOD: Solitary Gastric Polyp © Andrea Di Cataldo, Salvatore Pietro Dibenedetto, Rosalia Ragusa, Vincenzo Bagnara, and Sebastiano Cacciaguerra MALIGNANT OSTEOPETROSIS MANIFESTED AS JUVENILE CHRONIC MYELOID LEUKEMIA © A. Toren, Y. Neumann, J. J. Meyer, M. Mandel, G. Schiby, G. Kende, I. Bassat, and G. Rechavi HEPATOBLASTOMA AND HEPATOCELLULAR CARCINOMA IN CHILDREN © H. Mottl, T. Eckschlager, andJ . Snajdauf GRANULOCYTE COLONY-STIMULATING FACTOR ASSOCIATED LEUKOCYTOCLASTIC VASCULITIS MIMICKING HENOCH-SCHONLEIN PURPURA © Yih-Ming Yang, Vipul N. Mankad, and Elizabeth Manci MEGADOSE METHYLPREDNISOLONE FOR KASABACH-MERRITT SYNDROME © Sinasi Ozsoylu IMMUNOLOGY OF CHILDHOOD ACUTE IDIOPATHIC THROMBOCYTOPENIC PURPURA © Sinasi Ozsoylu MENINGEAL NEUROBLASTOMA AFTER COMPLETING THERAPY © Naoki Sakata, Jun Okamura, Haruhiko Eguchi, Yoshiko Ikuno, and Hideko Tasaka PAINLESS AND SAFE SUBCUTANEOUS CATHETER FOR INJECTION OF VARIOUS CYTOKINES IN PATIENTS WITH HEMATOLOGICAL DISORDERS © Yorikazu Ishikawa, Motohiko Okano, Hideki Arioka, Ryoji Kobayashi, Hiroyuki Naito, and Yukio Sakiyama LOCAL TREATMENT OF HEMANGIOMA OF THE UROGENITAL TRACT © I.M.B. Russel, P. A. Voite, M. E. Weyerman, and A. Vos CARDIAC LYMPHOMA PRESENTING WITH PERICARDIAL EFFUSION IN A PEDIATRIC PATIENT: Case Report, Management, and Literature Review © Frank E. Shafer, Gerard R. Martin, Bertrand Duval-Arnold, and Nita L. Seibel Number 3 Editorials MUNCHHAUSEN’S-BY-PROXY SYNDROME © Lars Holmberg CARDIOVASCULAR COLLAPSE AFTER HIGH DOSE METHYLPREDNISOLONE © I. J. Cohen Review Article POLYCYTHEMIA: A Review Article and Case Report of Erythrocytosis Secondary to Wilms’ Tumor © Abdul Kader Souid, A. Stephen Dubansky, Peter Richman, and P. David Sadowitz Articles CHILDREN WITH CANCER TALK ABOUT THEIR OWN DEATH WITH THEIR FAMILIES © Ann Goldman and Deborah Christie CENTRAL VENOUS CATHETER WITH SUBCUTANEOUS INJECTION PORT (PORT-A-CATH): 8 Years Clinical Follow Up With Children OF. Wesenberg, H. Flaatten, and C. W.J anssen Short Communications MUNCHAUSEN SYNDROME PRESENTING AS HEMOPHILIA: A Convenient and Economical “Steal’’ of Disease and Treatment Q Mouhab Ayass, Regina Bussing, and Paulette Mehta UNEXPLAINED MENORRHAGIA AND HEMATURIA: A Case Report of Munchausen’s Syndrome by Proxy © Abdul Kader Souid, Ken Korins, David Keith, Stephen Dubansky, and P. David Sadowitz CARDIORESPIRATORY DECOMPENSATION FOLLOWING METHYLPREDNISOLONE ADMINISTRATION © Kenneth G. Lucas, Denise L. Howrie, and Carol K. Phebus DESFERRIOXAMINE AND URINARY ZINC EXCRETION IN B-THALASSEMIA MAJOR © Zimriit Uysal, Nejat Akar, Sabri Kemahli, Nazli Dincer, and Ayten Arcasoy DIAMOND-BLACKFAN ANEMIA ASSOCIATED WITH TREACHER-COLLINS SYNDROME © Rashed Hasan and Susumu Inoue LONG-TERM CEREBRAL EFFECTS OF CNS CHEMOTHERAPY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA QO SoerenJ . Bakke, Aud Fossen, Ingebjoerg Storm-Mathiesen, and Sverre O. Lie CONGENITAL MICROANGIOPATHIC HAEMOLYTIC ANEMIA: A Variant of Thrombotic Thrombocytopenic Purpura? QO Patricia C. E. Sartori, M. S. Enayat, and PhilipJ .D arbyshire PRIMARY OCULAR RECURRENCE OF LEUKEMIA FOLLOWING BONE MARROW TRANSPLANT © Indira Sahdev, Mark E. Weinblatt, Harriet Lester, Paul T. Finger, and Joseph Kochen EFFECT OF NUTRITIONAL STATUS ON THE INCIDENCE OF INFECTION IN CHILDHOOD CANCER © Mary Munazza Taj, Andrew D. J. Pearson, David B. Mumford, and Lisa Price HEMOGLOBINOPATHIES IN THE DISTRICT OF ANTALYA, TURKEY QO Iffet Bircan, Sevim Sisli, Asaf Giiven, Sanda Cali, Olcay Yegin, Halil Ertug, Ayfer Giir Giiven, and Nejat Akar Letter to the Editor RECOMBINANT INTERFERON ALFA-2b THERAPY IN CHILDREN WITH IMMUNE THROMBOCYTOPENIC PURPURA Q Ammar Hayani, Donald H. Mahoney Jr., C. Philip Steuber, and Abdus Saleem Reply CENTRAL NERVOUS SYSTEM DISEASE IN CHILDHOOD ALL O A. Kreuger Number 4 NOTE FROM THE EDITOR Editorials PEDIATRIC HEMATOLOGY AND ONCOLOGY IN THE UNITED KINGDOM © Alan W. Craft and John S. Lilleyman DEFINITIONS AND DOGMA IN CHILDHOOD IDIOPATHIC THROMBOCYTOPENIC PURPURA © J.-S. Lilleyman Review Article PEDIATRIC HEMATOLOGY AND ONCOLOGY IN IRAN: Past and Present State © Mardawig Alebouyeh Short Communications CEREBROVASCULAR COMPLICATIONS OF L-ASPARAGINASE THERAPY IN CHILDREN WITH LEUKEMIA: Aphasia and Other Neuropsychological Deficits © A. Kingma, R. Y. J.T amminga, W. A. Kamps, R. Le Coultre, and R. J. Saan SPECTRUM OF CLINICAL MANIFESTATIONS OF ANTIPHOSPHOLIPID ANTIBODIES IN CHILDHOOD AND ADOLESCENCE © A. Toren, P. Toren, A. Many, M. Mandel, R. Mester, Y. Neumann, G. Kende, T. Moses, S. Gitel, M. Levanon, J. Davidsohn, E. Springer, I. Ben-Bassat, and G. Rechavi ORAL MEGADOSE METHYLPREDNISOLONE VERSUS INTRAVENOUS IMMUNOGLOBULIN FOR ACUTE CHILDHOOD IDIOPATHIC THROMBOCYTOPENIC PURPURA © Sinasi Ozsoylu, Tiilin R. Sayli, and Giilyiiz Oztiirk INTRAVENOUS CORTICOSTEROIDS VERSUS INTRAVENOUS GAMMAGLOBULIN IN THE TREATMENT OF ACUTE IMMUNE THROMBOCYTOPENIC PURPURA © Jeffrey D. Hord and Neil J. Grossman LOW FREQUENCY OF TRANSFUSION-RELATED DISEASE IN CHILDREN UNDERGOING PERIPHERAL BLOOD STEM CELL AUTOGRAFTS © Y. Takaue, Y. Okamoto, T. Watanabe, Y. Kawano, and Y. Kuroda RENAL AUTOTRANSPLANTATION—A KIDNEY SAVING PROCEDURE BEFORE SPINAL RADIOTHERAPY © R. Hitchcock, J. Kohler, P. G. Duffy, and P. S. Malone SQUAMOUS CELL CARCINOMA IN THE SACROCOCCYGEAL AREA: A Case Report and Review of the Literature QO Kamar Godder, Vildane Manzo, Joseph Kochen, and Ellen Kahn ACUTE FEBRILE NEUTROPHILIC DERMATOSIS (SWEET’S SYNDROME) IN MYELODYSPLASTIC SYNDROME © R.P.S. Bajwa, R. K. Marwaha, Gurjeewan Garewal, and M. Rajagopalan CASE OF A CHILD WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA DIAGNOSED BY FLOW CYTOMETRY QO Naoko Kinugawa, Tsutomu Shichishima, Junichi Nishimura, and Teruo Kitani CYTOMEGALOVIRUS INFECTION IN TWO INFANTS WITH CONGENITAL OR NEONATAL SOLID TUMORS © Giovanni Nigro, Uta Bartmann, Enrico Properzi, Andrea Torre, Amalia Schiavetti, and Manuel Castello LIMB CONGENITAL FIBROSARCOMA: Report of Two Cases and Review of the Literature © M. Weyl Ben Arush, Y. Ben Arie, V. Bialik, and I. Meller ALL-TRANS RETINOIC ACID AS AN ALTERNATIVE TO CHEMOTHERAPY IN THE TREATMENT OF ACUTE PROMYELOCYTIC LEUKEMIA © Thomas Kihne, Paul Imbach, Erich Signer, and Bruno Osterwalder AUTOIMMUNE NEUTROPENIA OF INFANCY AND EARLY CHILDHOOD © Joseph P. Neglia, Jan Watterson, Mary Clay, William Kline, Naomi L. C. Luban, Clark M. Smith II, and John R. Priest Letters to the Editor HIGH-DOSE INTRAVENOUS IMMUNOGLOBULIN THERAPY, BLOOD RHEOLOGY, AND SICKLE CELL ANEMIA QO Simone Gangarossa and Nunzia R. Lucini T CELL LEUKEMIA WITH PERICARDIAL EFFUSION AT DIAGNOSIS O Ying Wei Lin, Masaru Kubota, Masahiko Matsumura, Yuichi Akiyama, Kenya Nishioka, and Haruki Mikawa THROMBOCYTOPENIC PURPURA FOLLOWING DPT VACCINATION © LS. Arya, O. P. Ghai, and A. K. Saraya AVASCULAR NECROSIS OF BONES IN CHILDREN WITH SICKLE CELL ANEMIA © SS. Man and A. Koren Following Page 388 Title Page to Volume 10 Contents of Volume 10 Author Index to Volume 10 Subject Index to Volume 10