Pediatric Epilepsy Case Studies From Infancy and Childhood through Adolescence Edited by Kevin Chapman, MD Barrow Neurological Institute, Phoenix, AZ Jong M. Rho, MD Barrow Neurological Institute, Phoenix, AZ Boca Raton London New York CRC Press is an imprint of the Taylor & Francis Group, an informa business Cover illustration courtesy of the Barrow Neurological Institute (© 2007, Barrow) CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487‑2742 © 2009 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Printed in the United States of America on acid‑free paper 10 9 8 7 6 5 4 3 2 1 International Standard Book Number‑13: 978‑1‑4200‑8342‑2 (Hardcover) This book contains information obtained from authentic and highly regarded sources. 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Rho, Jong M. [DNLM: 1. Epilepsy‑‑Case Reports. 2. Adolescent. 3. Child. 4. Infant. WL 385 P377 2008] RJ496.E6P42 2008 618.92’853‑‑dc22 2008022878 Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com Contents Foreword.................................................................................................................xiii Preface......................................................................................................................xv Editors.....................................................................................................................xvii Contributors.............................................................................................................xix Section 1: the BaSicS Chapter 1 A.Pediatric.Epilepsy.Primer.......................................................................................3 James W. Owens, M.D., Ph.D. Chapter 2 Developmental.Pharmacokinetics:.Principles.and.Practice.....................................15 Gail D. Anderson, Ph.D. and Jong M. Rho, M.D. Chapter 3 Dietary.Therapies.for.Epilepsy.................................................................................29 Eric H. Kossoff, M.D. Chapter 4 Vagus.Nerve.Stimulation.Therapy............................................................................37 James W. Wheless, M.D. Chapter 5 Epilepsy.Surgery.in.Children...................................................................................49 Tobias Loddenkemper, M.D. Chapter 6 Status.Epilepticus......................................................................................................57 James J. Riviello, Jr., M.D. Section 2: the neonate Chapter 7 Benign.Familial.Neonatal.Seizures..........................................................................65 Eric Marsh, M.D., Ph.D. and Edward C. Cooper, M.D., Ph.D. i Contents Chapter 8 Hypoxic-Ischemic.Encephalopathy.(Neonatal.Seizures).........................................71 Mark S. Scher, M.D. Chapter 9 Ohtahara.Syndrome..................................................................................................79 W. Donald Shields, M.D. Section 3: the infant Chapter 10 Febrile.Seizures........................................................................................................87 Jeffrey R. Buchhalter, M.D., Ph.D. Chapter 11 Generalized.Epilepsy.with.Febrile.Seizures.Plus.(GEFS+)......................................93 Noel Baker, M.D. Chapter 12 Benign.Myoclonic.Epilepsy.of.Infancy....................................................................99 Kristen L. Park, M.D. and Douglas R. Nordli, Jr., M.D. Chapter 13 Severe.Myoclonic.Epilepsy.in.Infancy...................................................................105 Matthew M. Troester, D.O. Chapter 14 Infantile.Spasms.....................................................................................................109 Richard A. Hrachovy, M.D. and James D. Frost, Jr., M.D. Chapter 15 Gelastic.Seizures.....................................................................................................117 Yu-tze Ng, M.D., FRACP Chapter 16 Tuberous.Sclerosis.Complex...................................................................................125 Aimee F. Luat, M.D. and Harry T. Chugani, M.D. Chapter 17 Herpes.Simplex.Encephalitis..................................................................................133 Dave F. Clarke, M.D. Contents ii Chapter 18 Refractory.Status.Epilepticus.................................................................................141 James J. Riviello, Jr., M.D. Chapter 19 Myoclonus.Epilepsy.with.Ragged.Red.Fibers........................................................147 Russell P. Saneto, D.O., Ph.D. Chapter 20 Sturge–Weber.Syndrome........................................................................................153 Asit K. Tripathy, M.D. and Ajay Gupta, M.D. Section 4: the child Chapter 21 Benign.Epilepsy.of.Childhood.with.Central-Temporal.Spikes..............................161 Paul M. Levisohn, M.D. Chapter 22 Childhood.Absence.Epilepsy..................................................................................169 L. Matthew Frank, M.D. Chapter 23 Panayiotopoulos.Syndrome....................................................................................177 Korwyn Williams, M.D., Ph.D. Chapter 24 Complex.Partial.Seizures........................................................................................183 Angus A. Wilfong, M.D. Chapter 25 Lennox–Gastaut.Syndrome....................................................................................191 Jong M. Rho, M.D. Chapter 26 Nonconvulsive.Status.Epilepticus...........................................................................197 James J. Riviello, Jr., M.D. Chapter 27 Focal.Cortical.Dysplasia.........................................................................................201 Susan Koh, M.D. iii Contents Chapter 28 Landau–Kleffner.Syndrome...................................................................................209 John F. Kerrigan, M.D. Chapter 29 Continuous.Spike-and-Wave.Activity.during.Slow-Wave.Sleep.............................217 Kevin Chapman, M.D. Chapter 30 Rasmussen.Encephalitis..........................................................................................225 Daniel H. Arndt, M.D. and Raman Sankar, M.D., Ph.D. Chapter 31 Myoclonic–Astatic.Epilepsy...................................................................................231 A.G. Christina Bergqvist, M.D. Section 5: the adoleScent Chapter 32 Juvenile.Myoclonic.Epilepsy..................................................................................239 Cornelia Drees, M.D. Chapter 33 Epilepsy.in.Adolescent.Females.............................................................................245 Mary L. Zupanc, M.D. Chapter 34 Unverricht–Lundborg.Disease................................................................................251 Danielle M. Andrade, M.D.,M.Sc. and Berge A. Minassian, C.M., FRCP(C) Chapter 35 Post-Traumatic.Seizures.and.Epilepsy....................................................................257 Daniel H. Arndt, M.D. and Christopher C. Giza, M.D. Chapter 36 Reflex.Epilepsy.......................................................................................................265 Michael C. Kruer, M.D. and Colin M. Roberts, M.D. Contents ix Chapter 37 Autosomal.Dominant.Nocturnal.Frontal.Lobe.Epilepsy.......................................273 Kevin Chapman, M.D. Index ......................................................................................................................281
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