Table Of Content

Staff Clinical Director Joan M. Robinson, RN, MSN Clinical Project Manager Beverly Ann Tscheschlog, RN, MS Clinical Editor Joanne M. Bartelmo, RN, MSN Product Director David Moreau Senior Product Manager Diane Labus Editors Margaret Eckman, Debra Share Editorial Assistants Megan L. Aldinger, Karen J. Kirk, Jeri O’Shea, Linda K. Ruhf Art Director Elaine Kasmer Design Joseph John Clark Design Assistants Kate Zulak, Karen Kappe Nugent Illustrators Bot Roda, Judy Newhouse, Betty Winnberg Vendor Manager Karyn Crislip Senior Manufacturing Coordinator Beth J. Welsh Production Services SPi Global The clinical treatments described and recommended in this publication are based on research and consultation with nursing, medical, and legal authorities. To the best of our knowledge, these procedures reflect currently accepted practice. Nevertheless, they can’t be considered absolute and universal recommendations. For individual applications, all recommendations must be considered in light of the patient’s clinical condition and, before administration of new or infrequently used drugs, in light of the latest package-insert information. The authors and publisher disclaim any responsibility for any adverse effects resulting from the suggested procedures, from any undetected errors, or from the reader’s misunderstanding of the text. © 2013 by Lippincott Williams & Wilkins. All rights reserved. This book is protected by copyright. No part of it may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means—electronic, mechanical, photocopy, recording, or otherwise—without prior written permission of the publisher, except for brief quotations embodied in critical articles and reviews, and testing and evaluation materials provided by the publisher to instructors whose schools have adopted its accompanying textbook. For information, write Lippincott Williams & Wilkins, 323 Norristown Road, Suite 200, Ambler, PA 19002-2756. Printed in China. PathoIE5-010512 Library of Congress Cataloging-in-Publication Data Pathophysiology made incredibly easy!.—5th ed. p. ; cm. Includes bibliographical references and index. ISBN 978-1-4511-4623-3 I. Lippincott Williams & Wilkins. [DNLM: 1. Pathology—Nurses’ Instruction. QZ 4] 616.07—dc23 2011047464 Contents Contributors and consultants Not another boring foreword 1 Pathophysiology basics 2 Cardiovascular system 3 Respiratory system 4 Neurologic system 5 Gastrointestinal system 6 Musculoskeletal system 7 Endocrine system 8 Renal system 9 Hematologic system 10 Immune system 11 Infection 12 Cancer 13 Genetics Appendices and index Practice makes perfect Less common disorders Glossary Selected references Credits Index Contributors and consultants Alicia H. Anderson, RN, MSN Faculty II Mercy School of Nursing Charlotte, N.C. Salina Bednarek, RN, MSN Professor of Nursing Phoenix College Phoenix, Ariz. Cheryl L. Brady, RN, MSN Assistant Professor of Nursing Kent State University Salem, Ohio Sandra N. Burns, RN, MSN, PhD(c) Assistant Professor/Adjunct Faculty University of Southern Nevada Henderson, Nev. Nancy Haynes, RN, PhD, CCRN Associate Professor Saint Luke’s College of Health Sciences Kansas City, Mo. Lynn D. Kennedy, RN, MSN, CCRN Assistant Professor of Nursing Francis Marion University Florence, S.C. Catherine Lopez, RN, MEd, CIC Assistant Dean for Student Services LSUHSC School of Nursing New Orleans, La. Bernadette Madara, APRN, EdD, BC Professor of Nursing Southern Connecticut State University New Haven, Conn. Jody Ralph, RN, PhD Assistant Professor University of North Dakota Grand Forks, N.Dak. Denise R. York, RNC, MS, MEd, CNS Professor Columbus State Community College University of Phoenix Columbus, Ohio Not another boring foreword If you’re like me, you’re too busy caring for your patients to have the time to wade through a foreword that uses pretentious terms and umpteen dull paragraphs to get to the point. So let’s cut right to the chase! Here’s why this book is so terrific: It will teach you all the important things you need to know about pathophysiology. (And it will leave out all the fluff that wastes your time.) It will help you remember what you’ve learned. It will make you smile as it enhances your knowledge and skills. Don’t believe me? Try these recurring logos on for size: Now I get it! explains difficult concepts using illustrations and flowcharts. Battling illness provides the latest treatments for diseases and disorders. The genetic link connects genetics to many common disorders. Memory joggers offer mnemonics and other aids to help you understand and remember difficult concepts. See? I told you! And that’s not all. Look for me and my friends in the margins throughout this book. We’ll be there to explain key concepts, provide important care reminders, and offer reassurance. Oh, and if you don’t mind, we’ll be spicing up the pages with a bit of humor along the way, to teach and entertain in a way that no other resource can. I hope you find this book helpful. Best of luck throughout your career! Joy