Parkinson’s Disease and Movement Disorders PDF
Preview Parkinson’s Disease and Movement Disorders
Thank you for purchasing this e-book. To receive special offers and news about our latest products, sign up below. Or visit LWW.com 2 Parkinson’s Disease & Movement Disorders Sixth Edition 3 Parkinson’s Disease & Movement Disorders Sixth Edition JOSEPH JANKOVIC, MD Professor of Neurology Distinguished Chair in Movement Disorders Director, Parkinson’s Disease Center and Movement Disorders Clinic Department of Neurology Baylor College of Medicine Houston, Texas EDUARDO TOLOSA, MD Professor of Neurology Parkinson’s Disease and Movement Disorder Unit Neurology Service Hospital Clínic Universitari University of Barcelona Barcelona, Spain 4 5 Acquisitions Editor: Jamie Elfrank Product Development Editor: Andrea Vosburgh Marketing Manager: Stephanie Manzo Kindlick Production Project Manager: David Saltzberg Design Coordinator: Holly Reid McLaughlin Manufacturing Coordinator: Beth Welsh Prepress Vendor: S4Carlisle Publishing Services 6th edition Copyright © 2015 Wolters Kluwer. Copyright © 2007 Lippincott Williams & Wilkins, a Wolters Kluwer business. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information-storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as US government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at [email protected], or via our website at lww.com (products and services). 9 8 7 6 5 4 3 2 1 Library of Congress Cataloging-in-Publication Data Available upon request ISBN 978-1-6083-1176-7 eISBN 978-1-4963-1763-6 This work is provided “as is,” and the publisher disclaims any and all warranties, expressed or implied, including any warranties as to accuracy, comprehensiveness, or currency of the content of this work. This work is no substitute for individual patient assessment based upon health-care professionals’ examination of each patient and consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data, and other factors unique to the patient. The publisher does not provide medical advice or guidance, and this work is merely a reference tool. Health-care professionals, and not the publisher, are solely responsible for the use of this work, including all medical judgments and for any resulting diagnosis and treatments. Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and health-care professionals should consult a 6 variety of sources. When prescribing medication, health-care professionals are advised to consult the product information sheet (the manufacturer’s package insert) accompanying each drug to verify, among other things, conditions of use, warnings, and side effects and identify any changes in dosage schedule or contraindications, particularly if the medication to be administered is new, infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or otherwise, or from any reference to or use by any person of this work. LWW.com 7 Dag Aarsland, MD Professor of Clinical Dementia Research Alzheimer Research Centre, NVS Karolinska Institutet Stockholm, Sweden Alberto Albanese, MD Professor of Neurology Director, 1st Neurology Istituto Neurologico Carlo Besta Università Cattolica del Sacro Cuore Milano, Italy Karen Elta Anderson, MD Associate Professor of Psychiatry & Neurology Director, Georgetown MedStar Huntington’s Disease Care, Education and Research Center Department of Psychiatry & Department of Neurology Georgetown University Washington, District of Columbia Melissa J. Armstrong, MD, MSc Assistant Professor of Neurology Division of Movement Disorders University of Maryland School of Medicine Baltimore, Maryland Caterina Francesca Bagella, MD, PhD Neurologia I Istituto Neurologico Carlo Besta Milan, Italy Roger A. Barker, MRCP, PhD Professor of Clinical Neuroscience John Van Geest Centre for Brain Repair Department of Neurology 8 University of Cambridge Cambridge, United Kingdom Anna Rita Bentivoglio, MD, PhD Assistant Professor of Neurology Coordinator of the Movement Disorder Unit Department of Geriatrics, Neuroscience, Orthopaedics Institute of Neurology Catholic University Rome, Italy Kailash P. Bhatia, MD, FRCP Professor of Clinical Neurology Sobell Department of Movement Neuroscience Institute of Neurology University College London London, United Kingdom Bastiaan R. Bloem, MD, PhD Professor of Neurology Director, Parkinson Center Nijmegen Donders Institute for Brain, Cognition and Behaviour Department of Neuroloy Rasdboud University Medical Center Nijmegen, the Netherlands Kathrin Brockmann, MD Center of Neurology Department of Neurodegenerative Diseases Hertie-Institute for Clinical Brain Research University of Tübingen Tübingen, Germany Francisco Cardoso, MD, PhD, FAAN Professor of Neurology Director, Movement Disorders Clinic Neurology Service Department of Internal Medicine The Federal University of Minas Gerais Belo Horizonte, MG, Brazil Mar Carmona-Abellan, MD 9 Neurologist and Movement Disorders Research Fellow Department of Neurology Clinica Universidad de Navarra Pamplona, Spain Vijay Chandran, MBBS, DM Clinical Fellow Pacific Parkinson’s Research Centre University of British Columbia Vancouver, British Columbia, Canada K. Ray Chaudhuri, DSc, MD, FRCP(Edin), FRCP(Lond) Professor of Neurology Director, National Parkinson Foundation International Centre of Excellence Kings College London London, United Kingdom Leslie Cloud, MD, MSc Assistant Professor of Neurology Parkinson’s and Movement Disorders Center Virginia Commonwealth University School of Medicine Richmond, Virginia Cynthia L. Comella, MD, FAAN Professor of Neurology Department of Neurological Sciences Rush Medical College Chicago, Illinois Josep Dalmau, MD, PhD Catalan Institution for Research and Advanced Studies (ICREA) Hospital Clinic, University of Barcelona Barcelona, Spain; Adjunct Professor of Neurology University of Pennsylvania Philadelphia, Pennsylvania Günther Deuschl, MD, PhD Chairman, Department of Neurology Christian Albrechts University Kiel, Germany 10
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