Paediatric and Adolescent Gynaecology: A Multidisciplinary Approach PDF
Preview Paediatric and Adolescent Gynaecology: A Multidisciplinary Approach
Paediatric and Adolescent Gynaecology AMultidisciplinaryApproach Thisbookprovidesamultidisciplinaryoverviewofdevel- opmental anomalies, disorders and intersex conditions. Thesearecomplexconditionsthatdemandhighstandards of care and treatment by all healthcare professionals in- volvedwiththemanagementofthesepsychological,med- icalandsurgicalproblems.Thistextbook,whichinvolves leadinginternationalexpertsfromawiderangeofdisci- plines,aimstodistiltheirwealthofexpertiseandtoprovide thebestpossibleadviceandrecommendationsconcerning medicalintervention.Anotherimportantthemeisthepsy- chologicalwell-beingofthepatient,theneedforinformed consentandtherighttoknowone’sdiagnosis.Patientsand theirfamiliesexpecthighstandardsofcare,communica- tionandconsultation,andthisbookwillhelpdoctorsto achievethis. Inadditiontocoveringthemanagementofdisordersof development,comprehensivesectionsdiscussmenstrual cycleabnormalities,polycysticovarysyndrome,gynaeco- logical cancer the late effects of childhood cancer and fertilitypreservation,dermatologicalconditionsandinfec- tions. Emphasizingasitdoesthemultidisciplinaryapproachto healthcare,thebookwillbeessentialreadingforspecialists inpaediatricandadolescentgynaecology,reproductiveen- docrinologists,paediatricandplasticsurgeons,andclinical geneticists. Paediatric and Adolescent Gynaecology A Multidisciplinary Approach Editor-in-chief AdamH.Balen DepartmentofReproductiveMedicine, LeedsGeneralInfirmary,Leeds Co-editors SarahM.Creighton TheElizabethGarrettAndersonand ObstetricHospital,University CollegeLondonHospitals,London MelanieC.Davies ReproductiveMedicineUnit, UniversityCollegeLondonHospitals,London JaneMacDougall DepartmentofObstetricsandGynaecology, Addenbrooke’sHospital,Cambridge RichardStanhope InstituteofChildHealth,London publishedby the press syndicate of the university of cambridge ThePittBuilding,TrumpingtonStreet,Cambridge,UnitedKingdom cambridge university press TheEdinburghBuilding,CambridgeCB22RU,UK 40West20thStreet,NewYork,NY10011–4211,USA 477WilliamstownRoad,PortMelbourne,VIC3207,Australia RuizdeAlarco´n13,28014Madrid,Spain DockHouse,TheWaterfront,CapeTown8001,SouthAfrica http://www.cambridge.org (cid:1) C CambridgeUniversityPress2004 Thisbookisincopyright.Subjecttostatutoryexception andtotheprovisionsofrelevantcollectivelicensingagreements, noreproductionofanypartmaytakeplacewithout thewrittenpermissionofCambridgeUniversityPress. Firstpublished2004 PrintedintheUnitedKingdomattheUniversityPress,Cambridge TypefacesUtopia8.5/12pt.andDax SystemLATEX2ε [tb] AcataloguerecordforthisbookisavailablefromtheBritishLibrary ISBN0521809614hardback Everyefforthasbeenmadeinpreparingthisbooktoprovideaccurate Althoughcasehistoriesaredrawnfromactualcases,everyeffort andup-to-dateinformationwhichisinaccordwithaccepted hasbeenmadetodisguisetheidentitiesoftheindividuals standardsandpracticeatthetimeofpublication.Nevertheless,the involved. authors,editorsandpublishercanmakenowarrantiesthatthe Everyefforthasbeenmadetoreachcopyrightholders;the informationcontainedhereinistotallyfreefromerror,notleast publisherswouldliketohearfromanyonewhoserightstheyhave becauseclinicalstandardsareconstantlychangingthroughresearch unknowinglyinfringed. andregulation.Theauthors,editorsandpublisherthereforedisclaim ThepublisherhasuseditsbestendeavorstoensurethattheURLsfor allliabilityfordirectorconsequentialdamagesresultingfromtheuse externalwebsitesreferredtointhisbookarecorrectandactiveatthe ofmaterialcontainedinthisbook.Readersarestronglyadvisedtopay timeofgoingtopress.However,thepublisherhasnoresponsibilityfor carefulattentiontoinformationprovidedbythemanufacturerofany thewebsitesandcanmakenoguaranteethatasitewillremainliveor drugsorequipmentthattheyplantouse. thatthecontentisorwillremainappropriate. Contents Contributors vii Preface xiii PartI Normaldevelopment 1 Embryologyofthefemalegenitaltract 3 FergusCameronandCraigSmith 2 Moleculargeneticsofgonaddevelopment 9 AndrewSinclairandFergusCameron 3 Gonadotrophinreceptors 22 ManuelTena-Sempere,JeromeLevallet andIlpoHuhtaniemi 4 Normalchildhood,pubertyandadolescence 44 ClementinaLaRosa,CristinaTraggiaiand RichardStanhope 5 Controlofthemenstrualcycleand fertility 51 GillianLockwood 6 Nutritionandreproductivefunction 59 HowardS.Jacobs 7 Normalbladdercontrolandfunction 65 NikeshThiruchelvamandPeterM.Cuckow 8 Developmentofsexuality:psychological perspectives 77 LihMeiLiao PartII Managementofdevelopmental abnormalitiesofthegenitaltract 9 Managementofambiguousgenitaliaatbirth 97 GaryL.Warne v vi Contents 10 Imagingofthefemalepelvisinthe 25 Long-termsequelaeofgenitalsurgery 327 evaluationofdevelopmentalanomalies 104 SarahCreighton ChristopherSchelvan,MargaretA.Hall-Craggsand 26 Amenorrhoea 334 RosedeBruyn AdamH.Balen 11 Surgicalcorrectionofvaginalandother 27 Thepolycysticovarysyndromeand anomalies 120 adolescentwomen 342 JaneMacDougallandSarahCreighton AdamH.BalenandDavidDunger 12 Laparoscopictechniques 131 28 Menstrualdisordersinadolescentgirls 354 AzadS.NajmaldinandAlfredCutner EleonoraPorcuandStefanoVenturoli 13 Anonsurgicalapproachtothetreatment 29 Pelvicpain,ovariancystsand ofvaginalagenesis 147 endometriosisinadolescentgirls 359 JulieAldersonandJulieGlanville PaulL.Wood 14 Psychologicalcareindisordersofsexual 30 Prematureovarianfailureandovarianageing 373 differentiationanddetermination 158 ColinJ.DavisandGerardS.Conway PollyCarmichaelandJulieAlderson 31 Gynaecologicalcancersinchildhood 389 15 Theneedsoftheadolescentpatientand TitoLopes herparentsintheclinic 179 JaneMacDougall 32 Latereproductivesequelaeoftreatment forchildhoodcancer 397 16 Communicatingadiagnosis 193 AngelaB.Thomson,HilaryO.D.Critchley, GillianLockwood,AlanCooklinandSandraRamsden ChristopherJ.H.KelnarandW.HamishB.Wallace 17 Patientsandparentsindecisionmaking 33 Preservationoffertilitybeforecancertherapy 416 andmanagement 205 HelenM.PictonandAnthonyJ.Rutherford MargaretSimmonds 34 Themanagementofinfertilitywith surrogacyandeggdonation 428 PartIII Managementofspecificdisorders PeterR.BrinsdenandMelanieC.Davies 35 Dermatologicalconditionsofthefemale 18 Disordersofgrowthandpuberty 231 genitalia 444 CristinaTraggiaiandRichardStanhope LeithA.BanneyandJaneC.Sterling 19 Turner’ssyndrome 242 36 Vaginaldischarge 473 Per-OlofJanson,Marie-LouiseBarrena¨s,BeritKristro¨m, RosamundCoxandPaulWood CharlesHanson,AndersMo¨ller,Kerstin Wilhelmsen-LandinandKerstinAlbertsson-Wikland 37 Psychologicalgenderdevelopmentin individualsbornwithambiguousgenitalia 492 20 Androgeninsensitivitysyndromes 253 MelissaHines JarmoJa¨a¨skela¨inenandIeuanA.Hughes 38 Eatingdisordersinadolescence 509 21 RokitanskysyndromeandotherMu¨llerian NadiaMicali,PeterWebsterandJanetTreasure anomalies 267 D.KeithEdmonds 39 Nutritionalamenorrhoea:long-term sequelae 522 22 TheXYfemale 275 JoannaL.Fried,RussalindRamos CatherineL.Minto andMichelleP.Warren 23 Thegynaecologyofthemajor 40 Howtosetupaservice:howtoteachandtrain 533 genitourinaryanomalies 293 JaneMacDougall ChristopherR.J.Woodhouse 24 Congenitaladrenalhyperplasia 310 Index 541 GerardS.ConwayandPierreD.E.Mouriquand Colourplatesectionbetweenpages274and275 Contributors KerstinAlbertsson-Wikland EndocrineDivision SahlgrenskaUniversityHospital Go¨teborg Sweden JulieAlderson DepartmentofAdolescentPsychology AshleyWing StJames’Hospital LeedsLS97TF UK AdamH.Balen DepartmentofReproductiveMedicine LeedsGeneralInfirmary LeedsLS29NS UK LeithA.Banney DepartmentofDermatology Addenbrooke’sHospital CambridgeCB22SW UK Marie-LouiseBarrena¨s DepartmentofPaediatrics UniversityofGo¨teborg EastHospital 41685Go¨teborg Sweden vii viii Contributors PeterR.Brinsden SarahCreighton BournHallClinic TheElizabethGarrettAnderson Bourn andObstetricHospital CambsCB37TR UniversityCollegeLondonHospitals UK LondonWC1E6AU UK FergusCameron DepartmentofEndocrinologyandDiabetes HilaryO.D.Critchley andCentreforHormoneResearch SectionofObstetricsandGynaecology MurdochChildren’sResearchInstitute DepartmentofDevelopmental RoyalChildren’sHospital andReproductiveSciences FlemingtonRd UniversityofEdinburgh Parkville 37Chalmer’sSt Melbourne EdinburghEH39ET Victoria3052 UK Australia PeterCuckow GreatOrmondStreetHospitalforChildren PollyCarmichael andTheInstituteofUrology DepartmentofPsychologicalMedicine TheMiddlesexHospital GreatOrmondStreetHospital LondonW1N8AA GreatOrmondSt UK LondonWC1N3JH UK AlfredCutner ElizabethGarrettAndersonHospital AlanCooklin HuntleySt DepartmentofChildand LondonWC1E6AU AdolescentPsychiatricServices UK NorthHouse TheMiddlesexHospital MelanieC.Davies ClevelandSt ReproductiveMedicineUnit LondonW1T3AA UniversityCollegeLondonHospitals UK LondonWC1E6DH UK GerardS.Conway UniversityCollegeHospitalLondon ColinDavis HuntleySt DepartmentofGynaecology LondonWC1E6AU StBartholomew’sandtheRoyalLondonHospitals UK LondonE11BB UK SophieChristin-Maitre HospitalSaint-Antione RosedeBrun 184rueduFaubourgSaint-Antoine DepartmentofRadiology 75012Paris GreatOrmondStreetHospitalforChildren France LondonWC1N3JH UK RosamundCox KetteringGeneralHospital DavidDunger RothwellRd DepartmentofPaediatrics Kettering Addenbrooke’sHospital NorthantsNN168UZ CambridgeCB22SW UK UK Contributors ix D.KeithEdmonds IlpoHuhtaniemi DepartmentofGynaecology DepartmentofPhysiology InstituteofObstetricsandGynaecology UniversityofTurku HammersmithHospital Kiinamyllynkatu10 LondonW120NN 20520Turku UK Finland JarmoJa¨a¨skela¨inen JoannaL.Fried DepartmentofPaediatrics ColumbiaPresbyterianMedicalCenter Addenbrooke’sHospital 622West168thSt CambridgeCB22SW NewYork UK NY10032 USA HowardS.Jacobs EmeritusProfessorofReproductiveEndocrinology JulieGlanville MiddlesexHospital DepartmentofReproductiveMedicine LondonW1N8AA ClarendonWing UK LeedsGeneralInfirmary LeedsLS29NS Per-OlafJanson UK DepartmentofObstetricsandGynaecologyand InstituteoftheHealthoftheWomanandChild MargaretHall-Craggs UniversityofGo¨teborg DepartmentofRadiology EastHospital UCHHospitalsTrust 41685Go¨teborg MortimerSt Sweden LondonW1N8AA UK ChristopherJ.H.Kelnar SectionofChildLifeandHealth CharlesHanson DepartmentofDevelopmental DepartmentofObstetricsandGynaecologyand andReproductiveSciences InstituteoftheHealthoftheWomanandChild UniversityofEdinburgh UniversityofGo¨teborg 20SylvanPlace EastHospital EdinburghEH91UW 41685Go¨teborg UK Sweden BeritKristo¨m Go¨teborgPaediatricGrowthResearchCentre MelissaHines InstituteoftheHealthoftheWomanandChild DepartmentofPsychology UniversityofGo¨teborg CityUniversity EastHospital NorthamptonSquare 41685Go¨teborg LondonEC1V0HB Sweden UK ClementinaLaRosa IeuanA.Hughes DepartmentofPaediatricEndocrinology DepartmentofPaediatrics GreatOrmondStreetHospitalfor Addenbrooke’sHospital ChildrenandTheMiddlesexHospital CambridgeCB22SW LondonW1N8AA UK UK
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