PACES for the MRCP Senior Content Strategist: Pauline Graham Senior Content Development Specialist: Ailsa Laing Project Manager: Sruthi Viswam Designer: Christian Bilbow Illustration Manager: Jennifer Rose Illustrator: Oxford Illustrators PACES for the MRCP With 250 clinical cases Third edition Tim HallMBChB FRCP MRCGP DipClinEd FHEA Consultant in Geriatric Medicine and Acute and General (Internal) Medicine, Plymouth Hospitals NHS Trust/South West Peninsula Deanery, Plymouth, UK Edinburgh London New York Oxford Philadelphia St Louis Sydney Toronto 2013 An imprint of Elsevier Ltd. © 2013, Timothy Hall. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions. First edition 2003 Second edition 2008 Reprinted 2009 Third edition 2013 ISBN 978-0-7020-5141-8 E-book ISBN 978-0-7020-5466-2 British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging in Publication Data A catalog record for this book is available from the Library of Congress Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. The publisher’s policy is to use paper manufactured from sustainable forests Printed in China Contents Acknowledgements..............................................xi 1.11 Kartagener’s syndrome...........................38 Preface................................................................xiii 1.12 Tuberculosis ..........................................39 1.13 Idiopathic pulmonary fibrosis and interstitial lung disease .........................43 Introduction 1.14 Rheumatoid lung ..................................50 1.15 Hypersensitivity pneumonitis The Practical Assessment of Clinical (extrinsic allergic alveolitis) .................50 Examination Skills (PACES) ...........................1 1.16 Asbestos-related lung disease and PACES for the MRCP .......................................5 pneumoconiosis .....................................52 Further reading ...............................................8 1.17 Pulmonary sarcoidosis ...........................55 1.18 Pulmonary hypertension ........................58 1.19 Cor pulmonale .....................................60 Station 1 Respiratory and 1.20 Pulmonary embolism .............................61 abdominal system 1.21 Pleural effusion ....................................66 1.22 Pleural rub ..........................................71 1.23 Pneumothorax ......................................71 RESPIRATORY SYSTEM 1.24 Obstructive sleep apnoea–hypopnoea Examination of the respiratory system ........10 syndrome .............................................74 Cases 1.25 Lung transplant ....................................76 1.1 Chronic obstructive pulmonary disease ....14 ABDOMINAL SYSTEM 1.2 Consolidation .......................................21 Examination of the abdominal system ........77 1.3 Dullness at the lung base ......................22 Cases 1.4 Pneumonia ...........................................23 1.5 Lung cancer .........................................26 1.26 Chronic liver disease .............................81 1.6 Pancoast’s syndrome ..............................31 1.27 Jaundice ..............................................90 1.7 Superior vena cava obstruction ..............32 1.28 Ascites .................................................92 1.8 Collapse / pneumonectomy / lobectomy ......33 1.29 Alcoholic liver disease ...........................94 1.9 Bronchiectasis .......................................34 1.30 Viral hepatitis ......................................96 1.10 Cystic fibrosis .......................................36 1.31 Autoimmune hepatitis .........................100 v Contents Contents 1.32 Primary biliary cirrhosis .......................101 Abdominal problems ..................................158 1.33 Genetic haemochromatosis ...................103 2.3 Dyspepsia and upper gastrointestinal 1.34 Wilson’s disease ..................................105 bleeding .............................................158 1.35 Hepatomegaly.....................................106 2.4 Dysphagia ..........................................166 1.36 Splenomegaly .....................................108 2.5 Abdominal pain ..................................168 1.37 Hepatosplenomegaly ............................109 2.6 Altered bowel habit and lower 1.38 Felty’s syndrome ..................................109 gastrointestinal bleeding ......................171 1.39 Abdominal mass ..................................110 Cardiovascular problems ............................177 1.40 Crohn’s disease ....................................111 2.7 Weight gain, obesity, and prevention 1.41 Ulcerative colitis ..................................114 of cardiovascular disease .....................177 1.42 Enteric and urinary stomas...................117 2.8 Chest pain and stable angina ..............183 1.43 Carcinoid syndrome .............................118 2.9 Acute coronary syndrome .....................189 1.44 Chronic myeloid leukaemia .................120 2.10 Heart failure ......................................199 1.45 Polycythaemia vera, 2.11 Palpitations ........................................207 myeloproliferative disorders 2.12 Atrial fibrillation .................................211 and myelodysplasia .............................124 2.13 Dyslipidaemia ....................................218 1.46 Chronic lymphocytic leukaemia ............128 2.14 Hypertension ......................................227 1.47 Lymphadenopathy and lymphoma .........129 1.48 Polycystic kidney disease ......................133 Neurological problems ...............................234 1.49 Nephrotic syndrome ............................134 2.15 Headache ...........................................234 1.50 Renal transplant .................................135 2.16 Transient ischaemic attack ...................241 Further reading ...........................................138 2.17 Weakness and wasting ........................246 2.18 Multiple sclerosis ................................248 2.19 Tremor ...............................................252 Station 2 History-taking skills Rheumatological problems ........................254 INTRODUCTION TO HISTORY-TAKING SKILLS 2.20 Back pain and osteoporosis ..................254 2.21 Joint pain ..........................................261 Clinical reasoning .......................................142 Endocrine problems ...................................263 The traditional medical history model ......143 2.22 Type 1 diabetes mellitus ......................263 Incorporating the patient’s perspective – 2.23 Type 2 diabetes mellitus ......................271 ideas, concerns and expectations ...............143 Eye problems ..............................................278 History-taking skills – the communication 2.24 Visual loss .........................................278 skills that make history taking effective ....144 Renal and metabolic problems ..................279 The traditional model and communication skills – putting these together ....................147 2.25 Acute kidney injury .............................279 2.26 Chronic kidney disease ........................287 Cases 2.27 Glomerulonephritis .............................296 Respiratory problems ..................................149 2.28 Systemic vasculitis ...............................301 2.1 Breathlessness and other respiratory 2.29 Hypercalcaemia ..................................308 symptoms ...........................................149 2.30 Hyponatraemia ...................................315 2.2 Asthma ..............................................153 2.31 Poisoning and metabolic disturbance ....322 vi Contents Haematological problems ..........................327 3.6 Other right-sided heart murmurs .........472 3.7 Mixed valve disease .............................473 2.32 Anaemia ............................................327 3.8 Mitral valve prolapse ..........................474 2.33 Sickle cell disease and thalassaemia .....333 3.9 Prosthetic valves .................................475 2.34 Purpura .............................................338 3.10 Permanent pacemaker and cardiac 2.35 Haemophilia ......................................342 device therapies ..................................476 2.36 Deep vein thrombosis ..........................344 3.11 Infective endocarditis ..........................477 2.37 Thrombophilic tendency .......................347 3.12 Congenital acyanotic heart disease .......481 2.38 Myeloma ............................................351 3.13 Cyanotic heart disease .........................483 Other problems in acute and general 3.14 Hypertrophic (obstructive) medicine and elderly care ..........................357 cardiomyopathy ..................................484 2.39 Human immunodeficiency virus 3.15 Pericardial rub and pericardial infection ............................................357 disease ...............................................487 2.40 Falls ..................................................368 NERVOUS SYSTEM 2.41 Syncope ..............................................372 Examination of the nervous system ...........488 2.42 Seizures .............................................383 2.43 Delirium and acute confusion ..............391 Examination of the nervous system – 2.44 Mild cognitive impairment and overview ......................................................488 dementia ............................................396 Examination of the cranial nerves .............489 2.45 Incontinence .......................................408 Examination of higher cortical function 2.46 Raised inflammatory markers ................411 and specific lobes .......................................496 2.47 Polymyalgia and giant cell arteritis ......421 2.48 Pyrexia and sepsis ...............................425 Examination of speech and language ........498 2.49 Weight loss and malignancy ................435 Examination of coordination .....................501 2.50 Tiredness ............................................440 Examination of power and sensation – Further reading ...........................................442 overview ......................................................503 Examination of the upper limbs ................508 Station 3 Cardiovascular and Examination of the lower limbs .................512 nervous system Examination of gait ....................................514 Cases CARDIOVASCULAR SYSTEM 3.16 Visual field defects ..............................516 Examination of the cardiovascular 3.17 Ocular nerve lesions ...........................518 system ..........................................................452 3.18 Internuclear ophthalmoplegia ..............520 Cases 3.19 Nystagmus .........................................521 3.1 Mitral stenosis ....................................462 3.20 Ptosis .................................................523 3.2 Mitral regurgitation ............................465 3.21 Large pupil ........................................524 3.3 Aortic stenosis ....................................467 3.22 Small pupil ........................................525 3.4 Aortic regurgitation ............................469 3.23 Horner’s syndrome ..............................526 3.5 Tricuspid regurgitation and 3.24 Cerebellopontine angle syndrome..........527 Ebstein’s anomaly ...............................471 3.25 Facial nerve palsy ...............................529 vii Contents Contents 3.26 Bulbar palsy .......................................531 Cases 3.27 Anterior circulation stroke Discussing clinical management ................618 syndromes ..........................................532 4.1 Explaining a diagnosis ........................618 3.28 Dysphasia and dysarthria ....................548 4.2 Explaining an investigation .................619 3.29 Pseudobulbar palsy .............................549 4.3 Discussing treatment ...........................622 3.30 Agnosias and apraxias .........................550 4.4 Discussing management, prognosis 3.31 Posterior circulation stroke syndromes ...553 and possible complications in a 3.32 Parkinson’s disease ..............................556 patient with multiple problems.............625 3.33 Cerebellar disease ...............................565 4.5 Discussing diagnostic uncertainty .........626 3.34 Spastic paraparesis and 4.6 Discussing risk and treatment effect .....628 Brown–Séquard syndrome ....................566 4.7 Negotiating a management plan 3.35 Syringomyelia .....................................569 for a chronic disease / long-term 3.36 Absent ankle jerks and extensor condition ...........................................631 plantars .............................................569 4.8 Encouraging concordance with 3.37 Motor neurone disease ........................573 treatment and prevention ....................633 3.38 Cervical myeloradiculopathy ................577 Communication in special 3.39 Cauda equina syndrome ......................578 circumstances ..............................................635 3.40 Carpal tunnel syndrome (median nerve lesion) .....................................581 4.9 Cross-cultural communication ..............635 3.41 Ulnar nerve lesion ..............................583 4.10 Communicating with angry patients 3.42 Radial nerve lesion .............................585 or relatives .........................................636 3.43 Wasting of the small (intrinsic) 4.11 Communicating with upset or muscles of the hand ............................586 distressed relatives ..............................638 3.44 Common peroneal nerve lesion.............588 4.12 Discharge against medical advice .........639 3.45 Peripheral neuropathy .........................589 4.13 Delayed discharge ...............................641 3.46 Charcot–Marie–Tooth disease and Breaking bad news ......................................643 hereditary neuropathies .......................597 4.14 Cancer – potentially curable ................643 3.47 Guillain–Barré syndrome.....................598 4.15 Cancer – probably incurable ................646 3.48 Myasthenia gravis ...............................602 4.16 Cancer – patient not fit for active 3.49 Myopathy and myositis ........................604 treatment ...........................................648 3.50 Myotonic dystrophy ..............................610 4.17 Chronic disease ..................................650 Further reading ...........................................612 4.18 Discussing an acutely terminal situation with relatives ........................651 Confidentiality, consent and capacity ........653 Station 4 Communication skills and ethics 4.19 Legal points in confidentiality ..............653 4.20 Breaching confidentiality when a third party may be at risk ...................654 INTRODUCTION TO COMMUNICATION 4.21 Breaching confidentiality in the SKILLS AND ETHICS public interest ....................................656 Communication skills ................................616 4.22 Confidentiality when talking with Ethics ...........................................................617 relatives and other third parties ...........658 viii Contents 4.23 Consent for investigation or 4.46 HIV testing ........................................729 treatment ...........................................660 4.47 Needlestick injury ...............................730 4.24 Consent and capacity ..........................663 4.48 Medical opinion on fitness for 4.25 Refusal of consent ...............................668 anaesthesia ........................................732 4.26 Deliberate self-harm ...........................670 4.49 Fitness to drive ...................................734 End-of-life issues .........................................673 4.50 Industrial injury benefits .....................735 Further reading ...........................................737 4.27 End of life and palliative care ..............673 4.28 Advance decision making .....................681 4.29 Resuscitation status decision-making – Station 5 Integrated clinical discussion with patient ........................683 assessment 4.30 Resuscitation status decision-making – discussion with relative .......................688 SKIN PROBLEMS 4.31 Appropriateness of intensive therapy unit transfer .......................................690 Examination of the skin .............................740 4.32 Withholding and withdrawing Cases life-prolonging treatments – antibiotics 5.1 Psoriasis ............................................742 and drugs ..........................................692 5.2 Dermatitis .........................................746 4.33 Withholding and withdrawing 5.3 Lichen planus .....................................749 life-prolonging treatments – clinically 5.4 Blistering skin disorders ......................751 assisted nutrition and hydration ...........693 5.5 Facial rash .........................................756 4.34 Percutaneous endoscopic gastrostomy 5.6 Scleroderma, vitiligo and feeding ..............................................697 autoimmune skin disease .....................759 4.35 Vegetative state ...................................701 5.7 Oral lesions and nail lesions ................761 4.36 Brainstem death .................................705 5.8 Shin lesions ........................................764 4.37 Discussing live organ donation.............707 5.9 Neurofibromatosis and tuberose 4.38 Requesting an autopsy (post mortem) ..709 sclerosis .............................................767 Clinical governance .....................................711 5.10 Neoplastic skin lesions .........................771 4.39 Critical incident ..................................711 RHEUMATOLOGICAL PROBLEMS 4.40 Managing a complaint and the Examination of the joints ...........................774 question of negligence .........................714 4.41 Fitness to practise – poor performance Examination of the joints – overview ........774 in a colleague .....................................717 Examination of the hands and arms ..........777 4.42 Fitness to practise – misconduct in Examination of the legs ..............................782 a colleague .........................................720 4.43 Fitness to practise – health problems Examination of the spine ...........................784 in a colleague .....................................722 Cases 4.44 Recruitment to a randomised 5.11 Rheumatoid hands and rheumatoid controlled trial ...................................723 arthritis .............................................786 Other communication, ethical and 5.12 Ankylosing spondylitis and legal scenarios .............................................727 spondyloarthropathies ..........................793 4.45 Genetic testing ...................................727 5.13 Systemic lupus erythematosus ...............797 ix