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Oxford Handbook of Rheumatology PDF

832 Pages·2018·6.16 MB·English
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OXFORD MEDICAL PUBLICATIONS Oxford Handbook of Rheumatology Published and forthcoming Oxford Handbooks Oxford Handbook for the Foundation Programme 3e Oxford Handbook of Acute Medicine 3e Oxford Handbook of Anaesthesia 2e Oxford Handbook of Applied Dental Sciences Oxford Handbook of Cardiology Oxford Handbook of Clinical and Laboratory Investigation 3e Oxford Handbook of Clinical Dentistry 4e Oxford Handbook of Clinical Diagnosis 2e Oxford Handbook of Clinical Examination and Practical Skills Oxford Handbook of Clinical Haematology 3e Oxford Handbook of Clinical Immunology and Allergy 2e Oxford Handbook of Clinical Medicine—Mini Edition 8e Oxford Handbook of Clinical Medicine 8e Oxford Handbook of Clinical Pharmacy Oxford Handbook of Clinical Rehabilitation 2e Oxford Handbook of Clinical Specialties 8e Oxford Handbook of Clinical Surgery 3e Oxford Handbook of Complementary Medicine Oxford Handbook of Critical Care 3e Oxford Handbook of Dental Patient Care 2e Oxford Handbook of Dialysis 3e Oxford Handbook of Emergency Medicine 4e Oxford Handbook of Endocrinology and Diabetes 2e Oxford Handbook of ENT and Head and Neck Surgery Oxford Handbook of Expedition and Wilderness Medicine Oxford Handbook of Gastroenterology and Hepatology Oxford Handbook of General Practice 3e Oxford Handbook of Genitourinary Medicine, HIV, and Sexual Health 2e Oxford Handbook of Geriatric Medicine Oxford Handbook of Infectious Diseases and Microbiology Oxford Handbook of Key Clinical Evidence Oxford Handbook of Medical Sciences Oxford Handbook of Nephrology and Hypertension Oxford Handbook of Neurology Oxford Handbook of Nutrition and Dietetics Oxford Handbook of Obstetrics and Gynaecology 2e Oxford Handbook of Occupational Health Oxford Handbook of Oncology 3e Oxford Handbook of Ophthalmology Oxford Handbook of Paediatrics Oxford Handbook of Palliative Care 2e Oxford Handbook of Practical Drug Therapy 2e Oxford Handbook of Pre-Hospital Care Oxford Handbook of Psychiatry 2e Oxford Handbook of Public Health Practice 2e Oxford Handbook of Reproductive Medicine and Family Planning Oxford Handbook of Respiratory Medicine 2e Oxford Handbook of Rheumatology 3e Oxford Handbook of Sport and Exercise Medicine Oxford Handbook of Tropical Medicine 3e Oxford Handbook of Urology 2e Oxford Handbook of Rheumatology Fourth Edition Gavin Clunie Consultant Rheumatologist and Metabolic Bone Physician, Addenbrooke’s Hospital, Cambridge, UK Nick Wilkinson Consultant Paediatric and Adolescent Rheumatologist, Evelina London Children’s Hospital, London, UK Elena Nikiphorou Consultant Rheumatologist, Whittington Hospital; Clinical Researcher, Academic Rheumatology Department, King’s College London, UK Deepak Jadon Consultant Rheumatologist and Director of the Rheumatology Research Unit, Addenbrooke’s Hospital, Cambridge, UK Great Clarendon Street, Oxford, OX2 6DP, United Kingdom Oxford University Press is a department of the University of Oxford. It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. Oxford is a registered trade mark of Oxford University Press in the UK and in certain other countries © Oxford University Press 2018 The moral rights of the authors have been asserted First Edition published in 2002 Second Edition published in 2006 Third Edition published in 2011 Fourth Edition published in 2018 Impression: 1 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of Oxford University Press, or as expressly permitted by law, by licence or under terms agreed with the appropriate reprographics rights organization. Enquiries concerning reproduction outside the scope of the above should be sent to the Rights Department, Oxford University Press, at the address above You must not circulate this work in any other form and you must impose this same condition on any acquirer Published in the United States of America by Oxford University Press 198 Madison Avenue, New York, NY 10016, United States of America British Library Cataloguing in Publication Data Data available Library of Congress Control Number: 2017960672 ISBN 978–0–19–872825–2 eISBN 978–0–19–104394–9 Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up-to-date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breast-feeding Links to third party websites are provided by Oxford in good faith and for information only. Oxford disclaims any responsibility for the materials contained in any third party website referenced in this work. Foreword I am pleased to introduce you to the 4th edition of the Oxford Handbook of Rheumatology. This edition has increased in size, but continues to be just as accessible. It presents the reader with a pragmatic approach to making a differential diagnosis. The approach to thinking about how to make sense of the history and clinical findings is clear. The common rheumatological conditions are covered well, and the new edition incorporates relevant sections on paediatric and adolescent rheumatology. From the days of Sir William Osler, the art of listening to and observing the patient has been a key focus of what defines a good doctor. Medicine has advanced considerably since his day, but the core values of a physician have not changed. The focus on good clinical history taking and examination technique is a reminder of the core skill set that we use as physicians. When all else fails, go back to the basic principles, and back to the patient. This book shows us how important that skill set is. Professor Jane Dacre MD, PRCP President Royal College of Physicians London, UK Preface Rheumatic musculoskeletal conditions are common both in general and hospital practice. Musculoskeletal symptoms are a primary feature of many multisystem illnesses, not only in the autoimmune joint and connective tissue diseases, but also metabolic, endocrine, neoplastic, and infectious conditions. Symptoms are also common in the context of injury, age-related change, and psychological distress. Many conditions in rheumatology are a major source of morbidity and mortality. We have kept the format of the previous edition for this version but importantly have updated the text to include paediatric and adolescent rheumatology. Part I remains as a guide to evaluation of rheumatic and musculoskeletal disease from the point of referral and reflects the way clinical problems/symptoms present to the clinician in real life. We have considered how this happens for adults, and new in this version, for children and adolescents, affected by rheumatological and musculoskeletal disease. The reader will find detail on musculoskeletal anatomy and functional anatomy in this part of the book. Part II remains as the section of the book where the reader can find disease- specific information (e.g. spondyloarthritis, vasculitis, back pain, and so on). We have included paediatric sections in each chapter where there is relevance for disease occurring in children and adolescents, noting the difference in disease and its management in children and adolescents compared with adults. Part III remains as medicine management and contains chapters on drugs used in rheumatology practice, glucocorticoid injection therapy, and rheumatological emergencies. We have tried to avoid duplication but cross reference between chapters. We hope this book is helpful and informative for all doctors, physiotherapists, and specialist nursing practitioners who are faced with managing people and patients with undiagnosed musculoskeletal symptoms or established rheumatic musculoskeletal diseases. Acknowledgements The authors would like to acknowledge the work of the co-founder author-editor of the textbook Dr Alan Hakim for his contribution, whom together with Dr Clunie, devised and wrote the book from the first edition and co-author-editor Dr Inam Haq (who joined for the 2nd and 3rd editions), in helping to establish the Oxford Handbook of Rheumatology as the market leader small textbook for rheumatology.

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The Oxford Handbook of Rheumatology, 4th edition has been fully reviewed and updated to make it into an invaluable guide for students, trainees, consultant rheumatologists, and everyone caring for patients with musculoskeletal disease. With the addition of a paediatric rheumatologist to the editor t
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