Overview on Biocompatibilities of Implantable Biomaterials.

568 Pages·2013·85.683 MB·English

by  Rosario Pignatello

ADVANCES IN
BIOMATERIALS SCIENCE
AND BIOMEDICAL
APPLICATIONS
Edited by Rosario Pignatello
ADVANCES IN
BIOMATERIALS SCIENCE
AND BIOMEDICAL
APPLICATIONS
Edited by Rosario Pignatello
Advances in Biomaterials Science and Biomedical Applications
http://dx.doi.org/10.5772/56420
Edited by Rosario Pignatello
Contributors
Chowdhury, Xiaohong Wang, Irene Tereshko, Valery Tereshko, Patrick Frayssinet, Ben Ayed Foued, Shaojun Yuan,
Gordon Xiong, Ariel Roguin, Swee Hin Teoh, Cleo Choong, Tiago Pereira, Andrea Gartner, Paulo Armada-Da-Silva,
Cátia Pereira, Miguel França, Diana Morais, Miguel Rodrigues, Ascenção Lopes, José Domingos, Ana Lúcia Luís, Ana
Colette Maurício, Irina Amorim, Raquel Gomes, Xiongbiao Chen, Mituso Niinomi, Ylenia Zambito, Masaru Murata,
Young-Kyun Kim, Kyung-Wook Kim, Jeong Keun Lee, In-Woong Um, Stefano Geuna, Frank Xue Jiang, Yan-Ru Lou,
Carmen Escobedo-Lucea, Arto Urtti, Marjo Yliperttula, Juan Valerio Cauich-Rodríguez, Juliana Carvalho, Mhamdi Lotfi,
M. Nejib, M. Naceur, Lucie Germain, Jean-Michel Bourget, Maxime Guillemette, Teodor Veres, François A. Auger,
Ruggero Bettini, Susan Scholes, Thomas Joyce
Published by InTeOpP
Copyright © 2013 InTeOpP
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Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those
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Publishing Process Manager Oliver Kurelic
First published March, 2013
Printed in Croatia
Advances in Biomaterials Science and Biomedical Applications, Edited by Rosario Pignatello
p. cm.
ISBN-10 953-51-1051-9
ISBN-13 978-953-51-1051-4

Contents
Preface IX
Section 1 Characterization of Novel Biomaterials 1
Chapter 1 Biomedical Applications of Materials Processed in Glow
Discharge Plasma 3
V. Tereshko, A. Gorchakov, I. Tereshko, V. Abidzina and V. Red’ko
Chapter 2 Mechanical Properties of Biomaterials Based on Calcium
Phosphates and Bioinert Oxides for Applications in
Biomedicine 23
Siwar Sakka, Jamel Bouaziz and Foued Ben Ayed
Chapter 3 Degradation of Polyurethanes for Cardiovascular
Applications 51
Juan V. Cauich-Rodríguez, Lerma H. Chan-Chan, Fernando
Hernandez-Sánchez and José M. Cervantes-Uc
Chapter 4 Substrates with Changing Properties for Extracellular
Matrix Mimicry 83
Frank Xue Jiang
Section 2 Biocompatibility Studies 109
Chapter 5 Overview on Biocompatibilities of Implantable
Biomaterials 111
Xiaohong Wang
Chapter 6 In Vitro Blood Compatibility of Novel Hydrophilic Chitosan
Films for Vessel Regeneration and Repair 157
Antonello A. Romani, Luigi Ippolito, Federica Riccardi, Silvia
Pipitone, Marina Morganti, Maria Cristina Baroni, Angelo F.
Borghetti and Ruggero Bettini
VI Contents
Chapter 7 Amelioration of Blood Compatibility and Endothelialization of
Polycaprolactone Substrates by Surface-Initiated Atom Transfer
Radical Polymerization 177
Shaojun Yuan, Gordon Xiong, Ariel Roguin, Swee Hin Teoh and
Cleo Choong
Chapter 8 Cell Adhesion to Biomaterials: Concept of
Biocompatibility 207
M. Lotfi, M. Nejib and M. Naceur
Section 3 Drug and Gene Delivery 241
Chapter 9 Nanoparticles Based on Chitosan Derivatives 243
Ylenia Zambito
Chapter 10 pH-Sensitive Nanocrystals of Carbonate Apatite- a Powerful
and Versatile Tool for Efficient Delivery of Genetic Materials to
Mammalian Cells 265
Ezharul Hoque Chowdhury
Section 4 Biomaterials for Tissue Engineering and Regeneration 293
Chapter 11 Innovative Strategies for Tissue Engineering 295
Juliana Lott Carvalho, Pablo Herthel de Carvalho, Dawidson Assis
Gomes and Alfredo Miranda de Goes
Chapter 12 Biofabrication of Tissue Scaffolds 315
Ning Zhu and Xiongbiao Chen
Chapter 13 Biomaterials and Stem Cell Therapies for Injuries Associated to
Skeletal Muscular Tissues 329
Tiago Pereira, Andrea Gärtner, Irina Amorim, Paulo Armada-da-
Silva, Raquel Gomes, Cátia Pereira, Miguel L. França, Diana M.
Morais, Miguel A. Rodrigues, Maria A. Lopes, José D. Santos, Ana
Lúcia Luís and Ana Colette Maurício
Chapter 14 Alignment of Cells and Extracellular Matrix Within Tissue-
Engineered Substitutes 365
Jean-Michel Bourget, François A. Auger, Lucie Germain, Maxime
Guillemette and Teodor Veres
Contents VII
Chapter 15 Autograft of Dentin Materials for Bone Regeneration 391
Masaru Murata, Toshiyuki Akazawa, Masaharu Mitsugi, Md Arafat
Kabir, In-Woong Um, Yasuhito Minamida, Kyung-Wook Kim,
Young-Kyun Kim, Yao Sun and Chunlin Qin
Chapter 16 Healing Mechanism and Clinical Application of Autogenous
Tooth Bone Graft Material 405
Young-Kyun Kim, Jeong Keun Lee, Kyung-Wook Kim, In-Woong
Um and Masaru Murata
Chapter 17 The Integrations of Biomaterials and Rapid Prototyping
Techniques for Intelligent Manufacturing of
Complex Organs 437
Xiaohong Wang, Jukka Tuomi, Antti A. Mäkitie, Kaija-Stiina
Paloheimo, Jouni Partanen and Marjo Yliperttula
Chapter 18 Mesenchymal Stem Cells from Extra-Embryonic Tissues for
Tissue Engineering – Regeneration of the
Peripheral Nerve 465
Andrea Gärtner, Tiago Pereira, Raquel Gomes, Ana Lúcia Luís,
Miguel Lacueva França, Stefano Geuna, Paulo Armada-da-Silva and
Ana Colette Maurício
Section 5 Special Applications of Biomaterials 499
Chapter 19 Hydroxylapatite (HA) Powder for Autovaccination Against
Canine Non Hodgkin’s Lymphoma 501
Michel Simonet, Nicole Rouquet and Patrick Frayssinet
Chapter 20 Dental Materials 515
Junko Hieda, Mitsuo Niinomi, Masaaki Nakai and Ken Cho
Chapter 21 Ceramic-On-Ceramic Joints: A Suitable Alternative Material
Combination? 539
Susan C. Scholes and Thomas J. Joyce

Preface
A recent editorial production from InTech resulted in the publication of three volumes focused
on biomaterials. In those books, also edited by myself, the fundamental and applicative aspects
of biomaterials, in the wide connotation of the word, have been reviewed and supported by the
experimental work of many scientists, who from many years have dedicated their research to
this fascinating world, composed of many different skills, techniques and competencies.
When I was invited by the Publisher to coordinate a further editorial task on Biomaterials, I
was glad to help in collecting new contributions in this area of research and science. The scien‐
tific production in the field is, in fact, rapidly growing and updating, mainly on the fronts of
new and original applications of already known or novel compounds and polymers. As proof,
we easily received a high number of articles to be selected for composition of this new volume.
The chosen title gives a clear suggestion to the need of focusing all the basic studies, for in‐
stance the physico-chemical characterization of biomaterials, towards their potential applica‐
tions in biomedicine and drug delivery, or in any other relevant area of diagnosis, therapy,
surgical manipulation, and rehabilitation. Traditional, or ‘known’, biomaterials can now be
handled to meet specific medical needs, based on the large experience of their chemical, physi‐
cal and biological properties. Conversely, newly produced materials can be directly designed
and tailored to such requirements, so that novel and somewhat unexpected areas of applica‐
tion are continuously disclosed.
These considerations have been the basis of this editorial product. The contribution presented
consists of review articles, original researches and experimental reports from eminent interna‐
tional experts of the multidisciplinary world, which is required for an effective development
and utility of biomaterials. 21 chapters have been organized to explore different aspects of bio‐
materials science. From advanced means for the characterization and toxicological assessment
of new materials, passing through some ‘classical’ applications in nanotechnology and tissue
engineering, toward novel specific uses of these products, the volume is intended to give read‐
ers a view of the wide range of disciplines and methodologies that have been exploited to de‐
velop biomaterials with the physical and biological features needed for specific clinical and
medical purposes.
I hope that you reading these interesting chapters will prompt your interest research towards
the exciting field of biomaterials science and applications
Rosario Pignatello
Universita degli Studi di Catania, Italy