Table Of Content

ORGAN ALLOCATION Transplantation and Clinical Immunology Symposia Fondation Marcel Merieux VOLUME 30 Organ Allocation Proceedings of the 30th Conference on Transplantation and Clinical Immunology, 2-4 June, 1998 Edited by J.L. Touraine J. Traeger H. Betuel J.M. Dubernard J.P. Revillard C. Dupuy SPRINGER SCIENCE+ BUSINESS MEDIA, B.V. A C.I.P. Catalogue record for this book is available from the Library of Congress ISBN 978-94-010-6091-2 ISBN 978-94-011-4984-6 (eBook) DOI 10.1007/978-94-011-4984-6 Printed an acid-free paper AII Rights Reserved © 1998 by Springer Science+Business Media Dordrecht Originally published by Kluwer Academic Publishers in 1998 No part of the material protected by this copyright notice may be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or by any other information storage and retrieval system, without written permission from the copyright owner. Table of contents List ofcontributors IX Part 1: Overview oforgan allocation policies and strategies in different countries 1. Principles for allocation ofcadaver organs to transplant recipients and coordinating procedures in Spain 3 B. Miranda and J.M. Gonuilez-Posada 2. Principles and practice ofcadaver organ allocation in France 23 C. Jacquelinet and D. l;foussin 3. Principles for allocation ofcadaver organs to transplant recipients in Italy 29 M. Cardillo, M. Scalamogna, F. Poli and G. Sirchia 4. Allocation ofcadaver organs to transplant recipients in Scandiatransplant 37 M. Madsen, P. Asmundsson, I.B. Brekke, K. Hockerstedt, P. Kirkegaard, N.H. Persson and G. Tufveson 5. Principles for allocation ofcadaver organs to transplant recipients in the USA (UNOS) 45 WW Pfaff 6. Allocation ofkidneys in the UK 51 PJ. Morris and S.V Fuggle on behalfofthe Kidney Advisory Group ofUKTSSA Part 2: Principles underlying current policies in organ allocation 7. What to expect from a good kidney allocation system 57 G. Opelz and T. Wujciak 8. Allocation ofcadaver organs to transplant recipients in Eurotransplant: principles and policies, Anno 1998 61 J. De Meester and G.G. Persijn 9. Increasing kidney supply as the best solution to the allocation problem 67 PI. Terasaki, J.M. Cecka, D.W Gjertson, Y. Cho and S. Takemoto VI Table ofContents 10. Strategies in organ donation 73 R.A. Sells 11. World Health Organization guidelines on transplantation and the WHO Task Force 83 B.M. Dickens Part 3: Waiting list 12. The French liver transplant waiting list: 5-year analysis (1992-1996) 97 B. Suc 13. Predictors ofmultiple listing for cadaver kidney transplantation and the effects ofa ban on multiple listing in the United States - a summary 117 R.J. Ozminkowski, A.J. White, A. Hassol and M. Murphy 14. Allocation ofkidneys to patients on the transplant waiting list: a simulation-based policy model 133 S.A. Zenios, G.M. Chertow and L.M. Wein 15. Factors influencing early placement on the kidney transplant waiting list in the United States 135 B.L. Kasiske, W London and M. Ellison 16. The organ transplant waiting list in France 139 P. Romano, B. Boutin, J.-L. Golmard and D. Houssin Part 4: At-risk donors 17. Expanded donor pool 147 M. Manyalich, C. Cabrer, J. Sanchez, R. Valero, S. Lopez-Coli and D. Paredes 18. Non heart-beating donors 167 J.-P. Squif.fiet 19. How to reconcile viral safety and efficacy in organ procurement 169 H. Agut 20. The problem ofinfectious transmission from donors in organ transplantation 175 A. Pahissa 21. Further readings on allocation oforgans from at-risk donors 177 Table ofContents VB Part 5: Ischemia reperfusion and organ allocation 22. The inflammatory cascade ofliver ischemia and reperfusion: from the donor to the recipient 181 O. Le Moine, J. Deviere and M. Goldman 23. The role ofT-cell costimulatory pathways in ischemia-reperfusion injury 209 A. Chandraker and M.H. Sayegh 24. Interest in an anti-LFA-1 monoclonal antibody in the prevention ofreperfusion injury in kidney transplantation 215 M. Hourmant and J.P. Soulillou 25. Preservation solution in heart transplantation 225 P. Menasche 26. The impact ofischemia-reperfusion injury on specific and non-specific, early and late chronic events after organ transplantation 233 W Land and K. MejJmer 27. Pharmacological intervention to decrease ischemia-reperfusion injury 261 J.M. Grinyo Part 6: Living donors and organ allocation 28. Organ transplantation in Islam 269 M.A. Mahmoud 29. Liver donor transplantation in Sweden and other Nordic countries with emphasis on the benefits ofthe procedure 273 G. Tufveson, J. Wadstrom, A. Berstzel, I. Fehrman-Ekholm, M. Madsen and G. Tyden 30. Kidney exchange programs: an expanded view ofthe ethical issues 285 L.F. Ross and E.S. Woodle 31. Unconventional living kidney donors 297 A. Spital Index ofnames 311 List of contributors H. AGUT C. JACQUELINET Laboratoire de Virologie du CERVI Departement medical et scientifique Groupe Hospitalier Pitie-Salpt:triere Etablissement Franr;ais Des Greffes 83 bd de I'H6pitai 5rue Lacuee 75651 Paris Cedex 13 F-75012 Paris France France B.M. DICKENS B.L. KASISKE Faculty ofLaw Department ofMedicine University ofToronto Hennepin Country Medical Center 84 Queen's Park Crescent 701 Park Avenue Toronto Minneapolis Ontario MN 55415 M5S 2C5 USA Canada W. LAND L.F. ROSS University ofChicago Division ofTransplantation Surgery MacLean Center for Clinical Medical Klinikum Grosshadern Ethics University ofMunich (LMU) 5841 SMaryland Ave MC 6098 Marchioninistrasse 15 Chicago D-81377 Munich IL 60637 Germany USA O. LE MOINE J.M. GRINYO Department ofGastroenterology Hospital Bellvitge 808 route de Lennik Institut Catala de la Salut 1070 Brussels Feixa Llarga Belgium 08907 Barcelona Spain M. MADSEN Scandiatransplant M. HOURMANT Aarhus University Hospital Department ofNephrology and Clinical Skejby Sygehus Immunology and ITERT DK-8200 Aarhus N H6tel-Dieu Denmark University Hospital 44035 Nantes Cedex M.A. MAHMOUD France Consultant in Pediatric Nephrology D. HOUSSIN National Institute ofNephrology Etablissement Franr;ais Des Greffes and Urology, Cairo 28 rue de Charenton 148 Tahrir Street 75012 Paris Dokki, Giza France Egypt x List ofcontributors M. MANYALICH-VIDAL W.W. PFAFF Coordinacio de trasplantaments Department ofSurgery Hospital Clinic University ofFlorida Villarroel 170 PO Box 100286 08036 Barcelona Gainesville Spain FL 32610-0286 USA P. MENASCHE Department ofCardiovascular Surgery M.H. SAYEGH and INSERM U 127 Laboratory ofImmunogenetics Hopital Lariboisiere Renal Division 2rue Ambroise Pare Brigham and Women's Hospital 75475 Paris Cedex 10 Harvard Medical School France 75 Francis Street Boston B. MIRANDA MA 02115 Organizaci6n Nacional de Trasplantes USA (ONT) CjSinesio Delgado, no.8 M. SCALAMOGNA 28029 Madrid Ospedale MaggiorejPoliclinico Milano Spain Centro Trasfusionale Centro Interegionale di Riferimento P. MORRIS Nord Italia Transplant Nuffield Department ofSurgery via Francesco Sforza 35 University ofOxford Milano Oxford Radcliffe Hospital Italy Headington Oxford R.A. SELLS OX39DU Renal Transplant Unit UK Royal Liverpool University Hospital Liverpool G.OPELZ L78XP Institute ofImmunology UK University ofHeidelberg 1m Neuenheimer Feld 305 A. SPITAL D-69120 Heidelberg The Genesee Hospital Germany Division ofNephrology 224 Alexander Street A. PAHISSA Rochester Hospital General Vall D'Hebron NY 14607 Head ofInfectious Diseases Department USA Pg. Vall d'Hebron 119-12-08035 J.-P. SQUIFFLET Barcelona Department ofRenal and Pancreatic Spain Transplantation G.G. PERSIJN University ofLouvain Medical School Eurotransplant International Foundation Saint-Luc Hospital PO Box 2304 10 Hippocrate Ave 2301 CH Leiden B-1200 Brussels The Netherlands Belgium List ofcontributors xi B. SUC A.J. WHITE Centre Hospitalier Rangueil Abt Health Care Research Foundation Service de Chirurgie Digestive 55 Wheeler Street 1Avenue Jean Poulhes Cambridge 31403 Toulouse Cedex 4 MA 02138 France USA P.I. TERASAKI SA ZENIOS University ofCalifornia Assistant Professor ofOperations, UCLA Tissue Typing Laboratory Information and Technology Department ofSurgery Standford Graduate School ofBusiness 950 Veteran Avenue Stanford University Los Angeles 518 Memorial Way CA 90024-1652 Stanford USA CA 94305-5015 USA G. TUFVESON Department ofTransplantation Surgery Uppsala University Hospital S-751 85 Uppsala Sweden

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Over the last few years, transplantation knowledge and techniques, as well as insights into pharmacology, have improved, thus enabling greater access to transplantation for patients. The pool of organs for transplantation is stable, and therefore insufficient to cope with the growing demand. To adju
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Organ Allocation: Proceedings of the 30th Conference on Transplantation and Clinical Immunology, 2–4 June, 1998 PDF

304 Pages·1998·20.01 MB·English
by  B. Miranda
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ORGAN ALLOCATION Transplantation and Clinical Immunology Symposia Fondation Marcel Merieux VOLUME 30 Organ Allocation Proceedings of the 30th Conference on Transplantation and Clinical Immunology, 2-4 June, 1998 Edited by J.L. Touraine J. Traeger H. Betuel J.M. Dubernard J.P. Revillard C. Dupuy SPRINGER SCIENCE+ BUSINESS MEDIA, B.V. A C.I.P. Catalogue record for this book is available from the Library of Congress ISBN 978-94-010-6091-2 ISBN 978-94-011-4984-6 (eBook) DOI 10.1007/978-94-011-4984-6 Printed an acid-free paper AII Rights Reserved © 1998 by Springer Science+Business Media Dordrecht Originally published by Kluwer Academic Publishers in 1998 No part of the material protected by this copyright notice may be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or by any other information storage and retrieval system, without written permission from the copyright owner. Table of contents List ofcontributors IX Part 1: Overview oforgan allocation policies and strategies in different countries 1. Principles for allocation ofcadaver organs to transplant recipients and coordinating procedures in Spain 3 B. Miranda and J.M. Gonuilez-Posada 2. Principles and practice ofcadaver organ allocation in France 23 C. Jacquelinet and D. l;foussin 3. Principles for allocation ofcadaver organs to transplant recipients in Italy 29 M. Cardillo, M. Scalamogna, F. Poli and G. Sirchia 4. Allocation ofcadaver organs to transplant recipients in Scandiatransplant 37 M. Madsen, P. Asmundsson, I.B. Brekke, K. Hockerstedt, P. Kirkegaard, N.H. Persson and G. Tufveson 5. Principles for allocation ofcadaver organs to transplant recipients in the USA (UNOS) 45 WW Pfaff 6. Allocation ofkidneys in the UK 51 PJ. Morris and S.V Fuggle on behalfofthe Kidney Advisory Group ofUKTSSA Part 2: Principles underlying current policies in organ allocation 7. What to expect from a good kidney allocation system 57 G. Opelz and T. Wujciak 8. Allocation ofcadaver organs to transplant recipients in Eurotransplant: principles and policies, Anno 1998 61 J. De Meester and G.G. Persijn 9. Increasing kidney supply as the best solution to the allocation problem 67 PI. Terasaki, J.M. Cecka, D.W Gjertson, Y. Cho and S. Takemoto VI Table ofContents 10. Strategies in organ donation 73 R.A. Sells 11. World Health Organization guidelines on transplantation and the WHO Task Force 83 B.M. Dickens Part 3: Waiting list 12. The French liver transplant waiting list: 5-year analysis (1992-1996) 97 B. Suc 13. Predictors ofmultiple listing for cadaver kidney transplantation and the effects ofa ban on multiple listing in the United States - a summary 117 R.J. Ozminkowski, A.J. White, A. Hassol and M. Murphy 14. Allocation ofkidneys to patients on the transplant waiting list: a simulation-based policy model 133 S.A. Zenios, G.M. Chertow and L.M. Wein 15. Factors influencing early placement on the kidney transplant waiting list in the United States 135 B.L. Kasiske, W London and M. Ellison 16. The organ transplant waiting list in France 139 P. Romano, B. Boutin, J.-L. Golmard and D. Houssin Part 4: At-risk donors 17. Expanded donor pool 147 M. Manyalich, C. Cabrer, J. Sanchez, R. Valero, S. Lopez-Coli and D. Paredes 18. Non heart-beating donors 167 J.-P. Squif.fiet 19. How to reconcile viral safety and efficacy in organ procurement 169 H. Agut 20. The problem ofinfectious transmission from donors in organ transplantation 175 A. Pahissa 21. Further readings on allocation oforgans from at-risk donors 177 Table ofContents VB Part 5: Ischemia reperfusion and organ allocation 22. The inflammatory cascade ofliver ischemia and reperfusion: from the donor to the recipient 181 O. Le Moine, J. Deviere and M. Goldman 23. The role ofT-cell costimulatory pathways in ischemia-reperfusion injury 209 A. Chandraker and M.H. Sayegh 24. Interest in an anti-LFA-1 monoclonal antibody in the prevention ofreperfusion injury in kidney transplantation 215 M. Hourmant and J.P. Soulillou 25. Preservation solution in heart transplantation 225 P. Menasche 26. The impact ofischemia-reperfusion injury on specific and non-specific, early and late chronic events after organ transplantation 233 W Land and K. MejJmer 27. Pharmacological intervention to decrease ischemia-reperfusion injury 261 J.M. Grinyo Part 6: Living donors and organ allocation 28. Organ transplantation in Islam 269 M.A. Mahmoud 29. Liver donor transplantation in Sweden and other Nordic countries with emphasis on the benefits ofthe procedure 273 G. Tufveson, J. Wadstrom, A. Berstzel, I. Fehrman-Ekholm, M. Madsen and G. Tyden 30. Kidney exchange programs: an expanded view ofthe ethical issues 285 L.F. Ross and E.S. Woodle 31. Unconventional living kidney donors 297 A. Spital Index ofnames 311 List of contributors H. AGUT C. JACQUELINET Laboratoire de Virologie du CERVI Departement medical et scientifique Groupe Hospitalier Pitie-Salpt:triere Etablissement Franr;ais Des Greffes 83 bd de I'H6pitai 5rue Lacuee 75651 Paris Cedex 13 F-75012 Paris France France B.M. DICKENS B.L. KASISKE Faculty ofLaw Department ofMedicine University ofToronto Hennepin Country Medical Center 84 Queen's Park Crescent 701 Park Avenue Toronto Minneapolis Ontario MN 55415 M5S 2C5 USA Canada W. LAND L.F. ROSS University ofChicago Division ofTransplantation Surgery MacLean Center for Clinical Medical Klinikum Grosshadern Ethics University ofMunich (LMU) 5841 SMaryland Ave MC 6098 Marchioninistrasse 15 Chicago D-81377 Munich IL 60637 Germany USA O. LE MOINE J.M. GRINYO Department ofGastroenterology Hospital Bellvitge 808 route de Lennik Institut Catala de la Salut 1070 Brussels Feixa Llarga Belgium 08907 Barcelona Spain M. MADSEN Scandiatransplant M. HOURMANT Aarhus University Hospital Department ofNephrology and Clinical Skejby Sygehus Immunology and ITERT DK-8200 Aarhus N H6tel-Dieu Denmark University Hospital 44035 Nantes Cedex M.A. MAHMOUD France Consultant in Pediatric Nephrology D. HOUSSIN National Institute ofNephrology Etablissement Franr;ais Des Greffes and Urology, Cairo 28 rue de Charenton 148 Tahrir Street 75012 Paris Dokki, Giza France Egypt x List ofcontributors M. MANYALICH-VIDAL W.W. PFAFF Coordinacio de trasplantaments Department ofSurgery Hospital Clinic University ofFlorida Villarroel 170 PO Box 100286 08036 Barcelona Gainesville Spain FL 32610-0286 USA P. MENASCHE Department ofCardiovascular Surgery M.H. SAYEGH and INSERM U 127 Laboratory ofImmunogenetics Hopital Lariboisiere Renal Division 2rue Ambroise Pare Brigham and Women's Hospital 75475 Paris Cedex 10 Harvard Medical School France 75 Francis Street Boston B. MIRANDA MA 02115 Organizaci6n Nacional de Trasplantes USA (ONT) CjSinesio Delgado, no.8 M. SCALAMOGNA 28029 Madrid Ospedale MaggiorejPoliclinico Milano Spain Centro Trasfusionale Centro Interegionale di Riferimento P. MORRIS Nord Italia Transplant Nuffield Department ofSurgery via Francesco Sforza 35 University ofOxford Milano Oxford Radcliffe Hospital Italy Headington Oxford R.A. SELLS OX39DU Renal Transplant Unit UK Royal Liverpool University Hospital Liverpool G.OPELZ L78XP Institute ofImmunology UK University ofHeidelberg 1m Neuenheimer Feld 305 A. SPITAL D-69120 Heidelberg The Genesee Hospital Germany Division ofNephrology 224 Alexander Street A. PAHISSA Rochester Hospital General Vall D'Hebron NY 14607 Head ofInfectious Diseases Department USA Pg. Vall d'Hebron 119-12-08035 J.-P. SQUIFFLET Barcelona Department ofRenal and Pancreatic Spain Transplantation G.G. PERSIJN University ofLouvain Medical School Eurotransplant International Foundation Saint-Luc Hospital PO Box 2304 10 Hippocrate Ave 2301 CH Leiden B-1200 Brussels The Netherlands Belgium List ofcontributors xi B. SUC A.J. WHITE Centre Hospitalier Rangueil Abt Health Care Research Foundation Service de Chirurgie Digestive 55 Wheeler Street 1Avenue Jean Poulhes Cambridge 31403 Toulouse Cedex 4 MA 02138 France USA P.I. TERASAKI SA ZENIOS University ofCalifornia Assistant Professor ofOperations, UCLA Tissue Typing Laboratory Information and Technology Department ofSurgery Standford Graduate School ofBusiness 950 Veteran Avenue Stanford University Los Angeles 518 Memorial Way CA 90024-1652 Stanford USA CA 94305-5015 USA G. TUFVESON Department ofTransplantation Surgery Uppsala University Hospital S-751 85 Uppsala Sweden

Description:
Over the last few years, transplantation knowledge and techniques, as well as insights into pharmacology, have improved, thus enabling greater access to transplantation for patients. The pool of organs for transplantation is stable, and therefore insufficient to cope with the growing demand. To adju
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