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Occupational Exposure Assessment for Air Contaminants PDF

357 Pages·2005·9.155 MB·\357
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Occupational Exposure Assessment Air for Contaminants L1609_C000.fm Page ii Tuesday, February 15, 2005 10:13 AM Occupational Exposure Assessment Air for Contaminants Gurumurthy Ramachandran L1609 disclaimer Page 1 Friday, February 18, 2005 12:15 PM Published in 2005 by CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2005 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group No claim to original U.S. Government works Printed in the United States of America on acid-free paper 10 9 8 7 6 5 4 3 2 1 International Standard Book Number-10: 1-5667-0609-2 (Hardcover) International Standard Book Number-13: 978-1-5667-0609-4 (Hardcover) This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. No part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc. (CCC) 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. Library of Congress Cataloging-in-Publication Data Catalog record is available from the Library of Congress Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com Taylor & Francis Group and the CRC Press Web site at is the Academic Division of T&F Informa plc. http://www.crcpress.com L1609_C000.fm Page v Tuesday, February 15, 2005 10:13 AM Abstract Exposure assessment is a key responsibility for most practicing occupational hygien- ists and forms the basis for a required course in most graduate programs in industrial hygiene. Over the last three decades, significant progress has been made, not only in the technology of measuring air contaminants, but also in the statistical descrip- tions of exposure distributions and exposure assessment strategies. This book addresses the various aspects of occupational exposure assessment for air contami- nants as a coherent body of knowledge. The first few sections of the book describe the process of obtaining a number that represents the value of exposure to an air contaminant (gas, vapor, or aerosol) and the science and technology underlying this process. This necessarily involves a discussion of the physical properties of the contaminants and the way in which measurement technologies take advantage of these properties. Respiratory tract deposition of aerosols is treated in sufficient depth. Concepts of measurement uncer- tainty and error and the propagation of error in physical measurements are also addressed. The last section describes sources of variability in exposures, including a discussion of between- and within-worker variability, the statistics of exposure distributions, and exposure assessment strategies for routine monitoring as well as occupational epidemiology. This integrated approach is intended for use in a graduate or upper-level under- graduate course on occupational exposure assessment to airborne contaminants. The book targets students and practitioners in occupational hygiene and other environ- mental health disciplines. L1609_C000.fm Page vi Tuesday, February 15, 2005 10:13 AM L1609_C000.fm Page vii Tuesday, February 15, 2005 10:13 AM Author Gurumurthy Ramachandran is associate professor in the Division of Environmental Health Sciences of the School of Public Health at the University of Minnesota. Dr. Ramachandran has a Bachelor’s degree in electrical engineering from the Indian Institute of Technology, Mumbai, a Master’s degree in environmental engi- neering from the Virginia Institute of Technology, and a Ph.D. from the University of North Carolina, Chapel Hill. He is a Certified Industrial Hygienist (CIH). L1609_C000.fm Page viii Tuesday, February 15, 2005 10:13 AM L1609_C000.fm Page ix Tuesday, February 15, 2005 10:13 AM Preface I have been teaching a graduate course on occupational exposure assessment for air contaminants for almost a decade now. Occupational hygiene has lacked a book that addressed all aspects of exposure assessment for air contaminants as a coherent body of knowledge. This is despite the fact that exposure assessment is a key responsibility for most practicing occupational hygienists and forms the basis for a required course in most graduate programs in industrial hygiene. Although there are several books available on the measurement of air contaminants, they deal solely with the descrip- tion of the technology involved in monitoring air contaminants (again focusing only on gases and vapors or only on aerosols). Some of the books, although excellent reference books, are not suitable as textbooks for teaching. A good example is Air Sampling for Evaluation of Atmospheric Contaminants, published by the American Council of Governmental Industrial Hygienists (ACGIH) and updated every few years. Several excellent textbooks are available for teaching aerosol science, e.g., those by Hinds (1999) and Vincent (1995). However, they do not address gas and vapor monitoring. Another limitation of these books is that they fail to cover the context in which exposures are measured, the design of exposure assessment strat- egies, and the statistical interpretation of exposure measurements. Only one book (Mulhausen and Damiano, 1998), to my knowledge, deals with this important topic. I continue to recommend this excellent reference book to students. However, it does not describe the different schools of thought regarding exposure assessment strate- gies. It also does not describe the actual measurement methods. I wrote this book with the intention of addressing all of these important themes in one textbook. It is intended for use in a graduate or upper-level undergraduate course on occupational exposure assessment to airborne contaminants. It targets students and practitioners in occupational hygiene and other environmental health disciplines. The book covers not only the technological aspects of measuring air contaminants — gases, vapors, and aerosols — but also the occupational hygiene framework within which such measurements take place. Hence, it includes a solid treatment of exposure assessment strategies and statistics. The book is divided into four broad sections: (1) a short introduction that describes the framework for studying air pollutants in occupational environments, (2) properties and measurement of gases and vapors, (3) properties and measurement of aerosols, and (4) sources of variability in exposures and exposure assessment strategies. The first chapter provides the context of exposure in the continuum between contaminant sources and the final biologically relevant dose. Given that the focus is only on the measurement of exposures and not the measurement of dose, Section II and Section III deal with the measurement of air contaminants — gases, vapors, and aerosols. This portion of the book deals with the process of obtaining a number that represents the value of exposure to a con-

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