Second Edition Obstetrics and Gynaecology First edition authors: Nick Panay, Ruma Dutta, Audrey Ryan and J A Mark Broadbent Second Edition Obstetrics Series editor Daniel Horton-Szar, BSc(Hons), MBBS(Hons), MRCGP Northgate Medical Practice, Canterbury, Kent, UK and Gynaecology Maryam Parisaei, DFFP MRCOG Specialist Registrar in Obstetrics & Gynaecology, Barnet Hospital, London, UK Archana Shailendra, MBBS DGO Senior House Officer, Obstetrics & Gynaecology, Darent Valley Hospital, Dartford, Kent, UK Ruma Dutta, BSc MBBS MRCOG Consultant Obstetrician & Gynaecologist, Hillingdon Hospital NHS Trust, Uxbridge, Middlesex, UK J A Mark Broadbent, BSc FRCOG MFFP Consultant Obstetrician & Gynaecologist, Barnet and Chase Farm NHS Trust, Hertfordshire, UK Edinburgh • London • New York • Oxford • Philadelphia • St Louis • Sydney • Toronto 2008 Commissioning Editor: Alison Taylor Development Editor: Lulu Stader Project Manager: Andrew Palfreyman Page design: Sarah Russell Icon illustrations: Geo Parkin Cover design: Stewart Larking Illustration management: Merlyn Harvey © 2004, Elsevier Limited. © 2008, Elsevier Limited. 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First edition 2004 Second edition 2008 ISBN: 978-0-7234-3472-6 British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging in Publication Data A catalog record for this book is available from the Library of Congress Notice Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the/Authors assumes any liability for any injury and/or damage to persons or property arising out or related to any use of the material contained in this book. The Publisher The Publisher's policy is to use paper manufactured from sustainable forests Printed in China Preface It can be difficult for the contemporary medical student to gain a true insight into the careers of Obstetricians and Gynaecologists when some Foundation Schools proide as little as eight weeks’ training in Obstetrics and Gynaecology. With an eer increasing and oerwhelming body of medical knowledge, it is difficult enough to grasp a basic academic knowledge let alone be expected to gain important clinical experience in such a short period of time. This is compounded by the fact that O&G has medical, surgical and obstetric components all requiring different skills and thought processes. Learning from reference texts may allow the student to memorise the facts but not necessarily how to assimilate these facts in a clinical setting. This book presents the theory of O&G in a more clinically orientated manner, as the patient would present in the real life situation, that is, by symptoms. This should focus the student to help deelop an insight into the thought processes that will be necessary when they start seeing and managing patients. A good clinical history will focus on releant posities and negaties and proide a differential diagnosis on which to base releant inestigations and Part one is written with this in mind. Part two is presented with a focus on disease processes and proides insight into the diagnosis and management of common disorders. The use of algorithms, diagrams, ‘Hints and Tips’ boxes and the newly introduced ‘Communication’ boxes gies a clearer understanding of the processes inoled in managing patients as well as some of the more common pitfalls. The text is written not only by consultants but also by registrars so combining the wisdom of experience with the latest changes in modern practice. To reflect the latest assessment methods the self-assessment section has been altered for the second edition. More extended matching questions (EMQ’s) hae been added. These hae been shown to better assess the ability of the student to assimilate the information proided rather than just rely on a good memory, skills that will hopefully produce a better quality of doctor. Many students see the final MBBS examination as a huge hurdle. The Crash Course philosophy is to proide the student with the releant clinical knowledge and assessment techniques to be better able to oercome this hurdle with less fear and more confidence. J A Mark Broadbent BSc FRCOG MFFP More than a decade has now passed since work began on the Crash Course series. Medicine neer stands still, and the work of keeping this series releant for today’s students is an ongoing process. This second edition builds upon the success of the preceding books and incorporates a great deal of new and reised material, keeping the series up to date with the latest medical research and deelopments in pharma- cology and current best practice. As always, we listen to feedback from the thousands of students who use Crash Course and hae made further improements to the layout and structure of the books. Each chapter now starts with a set of learning objecties, and the self-assessment sections hae been enhanced and brought up to date with modern exam formats. We hae also worked to integrate material on communication skills and gems of clinical Preface wisdom from practising doctors. This will not only add to the interest of the text but will reinforce the principles being described. Despite fully reising the books, we hold fast to the principles on which we first deeloped the series: Crash Course will always bring you all the information you need to reise in compact, manageable olumes that integrate pathology and therapeutics with best clinical practice. The books still maintain the balance between clarity and conciseness, and proiding sufficient depth for those aiming at distinction. The authors are junior doctors who hae recent experience of the exams you are now facing, and the accuracy of the material is checked by senior clinicians and faculty members from across the UK. I wish you all the best for your future careers! Dr Dan Horton-Szar Series Editor i Dedications To my mum, dad, Golnaz and Behzad for their incredible love and support. MP To my teachers for training me in this wonderful speciality; to my parents and Shailu for their encouragement and support. AS To my dad, who would have been proud to see my name in print, and to my mum, who is. Also to Paul and Jack for all their patience and love. RD With thanks to Tim for all his support during the preparation of this second edition MB vii This page intentionally left blank Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .v Examination for prolapse . . . . . . . . . . . . .30 Dedications. . . . . . . . . . . . . . . . . . . . . . . . . . . . .vii Investigation of prolapse . . . . . . . . . . . . .31 Glossary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xv .7 .. .The.menopause. . . . . . . . . . . . . . . . . . . . . .33 Part I The Patient Presents Presentation and differential with . . . . . . . . . . . . . . . . . . . . . . 1 diagnosis . . . . . . . . . . . . . . . . . . . . . . . . .33 Bleeding disturbances . . . . . . . . . . . . . . .33 .1 .. Abnormal.uterine.bleeding. . . . . . . . . . . . . . .3 Vasomotor symptoms . . . . . . . . . . . . . . .33 Absent periods . . . . . . . . . . . . . . . . . . . . . .3 Psychological symptoms . . . . . . . . . . . . .34 Heavy periods . . . . . . . . . . . . . . . . . . . . . .6 Intermediate menopause Intermenstrual and postcoital bleeding . . . .7 symptoms . . . . . . . . . . . . . . . . . . . . . . . .34 Painful periods . . . . . . . . . . . . . . . . . . . . . .7 Long-term symptoms of the Examination . . . . . . . . . . . . . . . . . . . . . . .8 menopause . . . . . . . . . . . . . . . . . . . . . .35 Postmenopausal bleeding . . . . . . . . . . . . .8 .8 .. Subfertility. . . . . . . . . . . . . . . . . . . . . . . . . .37 .2 .. .Pelvic.pain.and.dyspareunia. . . . . . . . . . . . .11 Taking the history . . . . . . . . . . . . . . . . . .37 Differential diagnosis . . . . . . . . . . . . . . . .11 Examination . . . . . . . . . . . . . . . . . . . . . .39 History to focus on the differential Investigation of subfertility . . . . . . . . . . . .39 diagnosis of pelvic pain and dyspareunia . . . . . . . . . . . . . . . . . . . . . . .11 .9 .. .Bleeding.and/or.pain.in.early.. Examination of patients with pelvic pregnancy. . . . . . . . . . . . . . . . . . . . . . . . . . .43 pain and dyspareunia . . . . . . . . . . . . . . . .13 History for bleeding/pain Investigations of patients who have in early pregnancy . . . . . . . . . . . . . . . . . .43 pelvic pain and dyspareunia . . . . . . . . . . .14 Examining women with pain and/ or bleeding in early pregnancy . . . . . . . . .44 .3 .. Vaginal.discharge. . . . . . . . . . . . . . . . . . . . .17 Differential diagnosis . . . . . . . . . . . . . . . .17 Investigation of bleeding and/ Examination of patients with or pain in early pregnancy . . . . . . . . . . . .45 vaginal discharge . . . . . . . . . . . . . . . . . . .18 Recurrent miscarriage . . . . . . . . . . . . . . .46 Investigation of patients with Trophoblastic disease . . . . . . . . . . . . . . . .47 vaginal discharge . . . . . . . . . . . . . . . . . . .19 10 .. .Bleeding.in.the.second.and.third.. .4 .. Vulval.symptoms. . . . . . . . . . . . . . . . . . . . .21 trimesters.of.pregnancy. . . . . . . . . . . . . . . .49 History . . . . . . . . . . . . . . . . . . . . . . . . . .21 Differential diagnosis of bleeding . . . . . . .49 Examination . . . . . . . . . . . . . . . . . . . . . .21 History to focus on the differential diagnosis of bleeding . . . . . . . . . . . . . . . .49 .5 .. Urinary.incontinence. . . . . . . . . . . . . . . . . . .25 Examination of patients who have History . . . . . . . . . . . . . . . . . . . . . . . . . .25 bleeding in the second and Examination . . . . . . . . . . . . . . . . . . . . . .26 third trimesters . . . . . . . . . . . . . . . . . . . .50 Investigations . . . . . . . . . . . . . . . . . . . . .27 Investigation of patients who have bleeding in the second and .6 .. Prolapse. . . . . . . . . . . . . . . . . . . . . . . . . . . .29 third trimesters . . . . . . . . . . . . . . . . . . . .50 Differential diagnosis . . . . . . . . . . . . . . . .29 Management of patients who have History to focus on the differential bleeding in the second and diagnosis of prolapse . . . . . . . . . . . . . . . .29 third trimesters . . . . . . . . . . . . . . . . . . . .51 ix
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